All Relations between oxtr and oxytocin

Publication Sentence Publish Date Extraction Date Species
V Lecompte, S Robins, L King, E Solomonova, N Khan, E Moss, C Nagy, N Feeley, I Gold, B Hayton, G Turecki, P Zelkowit. Examining the role of mother-child interactions and DNA methylation of the oxytocin receptor gene in understanding child controlling attachment behaviors. Attachment & human development. vol 23. issue 1. 2021-10-25. PMID:31900042. this study examined mother-child interactions and dna methylation of the oxytocin receptor (oxtr) gene in the child, in relation with controlling-attachment behaviors at early preschool age. 2021-10-25 2023-08-13 Not clear
Cheng-Qi Cao, Li Wang, Ruo-Jiao Fang, Gen Li, Ping Liu, Shu Luo, Xiang-Yang Zhan. Oxytocin receptor variant rs53576 genotype is associated with dysphoric arousal symptoms of DSM-5 posttraumatic stress disorder in Chinese earthquake survivors. Chinese journal of traumatology = Zhonghua chuang shang za zhi. vol 24. issue 4. 2021-10-25. PMID:33863620. evidence suggests that the oxytocin receptor (oxtr) gene may be involved in the psychopathology of posttraumatic stress disorder (ptsd). 2021-10-25 2023-08-13 Not clear
Carles Tapias-Espinosa, Toni Cañete, Daniel Sampedro-Viana, Tomasz Brudek, Anna Kaihøj, Ignasi Oliveras, Adolf Tobeña, Susana Aznar, Alberto Fernández-Terue. Oxytocin attenuates schizophrenia-like reduced sensorimotor gating in outbred and inbred rats in line with strain differences in CD38 gene expression. Physiology & behavior. vol 240. 2021-10-25. PMID:34364851. to explore whether these divergent effects were associated with differences in oxytocinergic mechanisms, we analyzed gene expression of the oxytocin receptor (oxtr) and the regulator of oxytocin release (cd38) in the mpfc of the roman rats. 2021-10-25 2023-08-13 rat
Carles Tapias-Espinosa, Toni Cañete, Daniel Sampedro-Viana, Tomasz Brudek, Anna Kaihøj, Ignasi Oliveras, Adolf Tobeña, Susana Aznar, Alberto Fernández-Terue. Oxytocin attenuates schizophrenia-like reduced sensorimotor gating in outbred and inbred rats in line with strain differences in CD38 gene expression. Physiology & behavior. vol 240. 2021-10-25. PMID:34364851. consistent with the differential oxytocin effects on ppi (rha > rla), constitutive cd38 expression was reduced in the rha rats compared to the rlas, while oxytocin administration increased oxtr expression in both strains. 2021-10-25 2023-08-13 rat
Nayna Sanathara, Lamees Alhassen, Ilias Marmouzi, Mohammad Khoudari, Joseph Phan, Wedad Alhassen, Olivier Civelli, Amal Alachka. Oxytocin-MCH circuit regulates monosynaptic inputs to MCH neurons and modulates social recognition memory. Neuropharmacology. vol 184. 2021-10-22. PMID:33290754. we selectively deleted oxytocin receptors (oxtr) from mch neurons (oxtr-cko mice) using a cre/loxp recombinase-technology, and used rabies-mediated circuit mapping technique to reveal the changes in the direct monosynaptic inputs to mch neurons. 2021-10-22 2023-08-13 mouse
Yi-Ju Lee, Hwai-Ting Lin, Muhammad Asad Chaudhary, Yi-Ching Lee, Dean-Chuan Wan. Effects of Prenatal Phthalate Exposure and Childhood Exercise on Maternal Behaviors in Female Rats at Postpartum: A Role of International journal of molecular sciences. vol 22. issue 18. 2021-10-21. PMID:34576011. epigenetic modification of the oxytocin receptor gene (oxtr) through dna methylation has been associated with the pathogenesis of neuropsychiatric disorders. 2021-10-21 2023-08-13 rat
Sara Palumbo, Veronica Mariotti, Teresa Anastasio, Giuseppina Rota, Laura Lucchi, Andrea Manfrinati, Rino Rumiati, Lorella Lotto, Michela Sarlo, Pietro Pietrini, Silvia Pellegrin. A genetic profile of oxytocin receptor improves moral acceptability of outcome-maximizing harm in male insurance brokers. Behavioural brain research. vol 392. 2021-10-13. PMID:32387223. here, we utilized a moral judgment paradigm to test the potential effects on moral choices of three polymorphisms of the oxytocin receptor (oxtr): rs53576, rs2268498 and rs1042770. 2021-10-13 2023-08-13 Not clear
Laura Lemel, Katarzyna Nieścierowicz, M Dolores García-Fernández, Leonardo Darré, Thierry Durroux, Marta Busnelli, Mylène Pezet, Fabrice Rébeillé, Juliette Jouhet, Bernard Mouillac, Carmen Domene, Bice Chini, Vadim Cherezov, Christophe J Morea. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules. Journal of lipid research. vol 62. 2021-10-12. PMID:33647276. the oxytocin receptor (oxtr) is involved in parturition and lactation of mammals and in their emotional and social behaviors. 2021-10-12 2023-08-13 Not clear
Sophie N Lee, Jenna Kraska, Melissa Papargiris, Linda Teng, Birunthi Niranjan, Johanna Hammar, Andrew Ryan, Mark Frydenberg, Nathan Lawrentschuk, Ralf Middendorff, Stuart J Ellem, Michael Whittaker, Gail P Risbridger, Betty Exintari. Oxytocin receptor antagonists as a novel pharmacological agent for reducing smooth muscle tone in the human prostate. Scientific reports. vol 11. issue 1. 2021-10-12. PMID:33737570. we show that the oxytocin receptor (oxtr) is widely expressed in the human prostate, and co-localises to contractile cells within the prostate stroma. 2021-10-12 2023-08-13 human
Julia Hofmann, Christine Huber, Bozidar Novak, Monika Schreckenbach, Christine F Schubert, Chadi Touma, Bart Pf Rutten, Ulrike Schmid. Oxytocin receptor is a potential biomarker of the hyporesponsive HPA axis subtype of PTSD and might be modulated by HPA axis reactivity traits in humans and mice. Psychoneuroendocrinology. vol 129. 2021-10-11. PMID:33975150. as, i, we recently discovered the intranasal neuropeptide oxytocin to reduce experimentally provoked ptsd symptoms, ii, expression of its receptor (oxtr) has hitherto not been assessed in ptsd patients, and iii, oxytocin and oxtr have previously been related to the hpa axis, we considered both as suitable candidates. 2021-10-11 2023-08-13 mouse
Julia Hofmann, Christine Huber, Bozidar Novak, Monika Schreckenbach, Christine F Schubert, Chadi Touma, Bart Pf Rutten, Ulrike Schmid. Oxytocin receptor is a potential biomarker of the hyporesponsive HPA axis subtype of PTSD and might be modulated by HPA axis reactivity traits in humans and mice. Psychoneuroendocrinology. vol 129. 2021-10-11. PMID:33975150. during a trier social stress test (tsst), we compared serum oxytocin and blood oxtr mrna concentrations between female ptsd patients, their hpa axis reactivity subtypes and sex and age-matched healthy controls (hc). 2021-10-11 2023-08-13 mouse
Julia Hofmann, Christine Huber, Bozidar Novak, Monika Schreckenbach, Christine F Schubert, Chadi Touma, Bart Pf Rutten, Ulrike Schmid. Oxytocin receptor is a potential biomarker of the hyporesponsive HPA axis subtype of PTSD and might be modulated by HPA axis reactivity traits in humans and mice. Psychoneuroendocrinology. vol 129. 2021-10-11. PMID:33975150. to assess the influence of (traumatic) stress on the cerebral expression of oxytocin and its receptor and to test their suitability as biomarkers for the mouse ptsd-like syndrome, we then analyzed oxytocin, its mrna (oxt) and oxtr mrna in three relevant brain regions and oxt in blood of a ptsd mouse model. 2021-10-11 2023-08-13 mouse
Laura Ramo-Fernández, Anja M Gumpp, Christina Boeck, Sabrina Krause, Alexandra M Bach, Christiane Waller, Iris-Tatjana Kolassa, Alexander Karabatsiaki. Associations between childhood maltreatment and DNA methylation of the oxytocin receptor gene in immune cells of mother-newborn dyads. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34471100. the neuropeptide oxytocin (oxt) and its receptor (oxtr) modulate interpersonal relationships, particularly mother-child interactions. 2021-10-11 2023-08-13 Not clear
Jin Liu, Siyuan Shang, Meng Pei, Yanjie S. Influence of Two Single-Nucleotide Polymorphisms of the Oxytocin Receptor Gene (OXTR) on Empathy: the Mediation Role of a Primary Emotion, CARE. Journal of molecular neuroscience : MN. vol 71. issue 2. 2021-10-05. PMID:32607757. influence of two single-nucleotide polymorphisms of the oxytocin receptor gene (oxtr) on empathy: the mediation role of a primary emotion, care. 2021-10-05 2023-08-13 human
Jin Liu, Siyuan Shang, Meng Pei, Yanjie S. Influence of Two Single-Nucleotide Polymorphisms of the Oxytocin Receptor Gene (OXTR) on Empathy: the Mediation Role of a Primary Emotion, CARE. Journal of molecular neuroscience : MN. vol 71. issue 2. 2021-10-05. PMID:32607757. these studies suggest that the maternal care instinct may mediate the effect of oxytocin receptor gene (oxtr) on empathy. 2021-10-05 2023-08-13 human
Corinne D Warrener, Edward M Valentin, Camilla Gallin, Lynnet Richey, Deanna B Ross, Chelsea J Hood, Adriana Lori, Joseph Cubells, Sheila A M Rauch, James K Rillin. The role of oxytocin signaling in depression and suicidality in returning war veterans. Psychoneuroendocrinology. vol 126. 2021-10-02. PMID:33582574. in this cross-sectional study, male veterans from the iraq and afghanistan wars (n = 86) provided blood and urine samples for measurement of peripheral oxytocin (ot) levels, as well as saliva samples for dna extraction followed by genotyping of oxytocin receptor gene (oxtr) single nucleotide polymorphisms, and cpg-methylation assessment. 2021-10-02 2023-08-13 human
Michelle T Siu, Sarah J Goodman, Isaac Yellan, Darci T Butcher, Maryam Jangjoo, Daria Grafodatskaya, Rageen Rajendram, Youliang Lou, Rujun Zhang, Chunhua Zhao, Rob Nicolson, Stelios Georgiades, Peter Szatmari, Stephen W Scherer, Wendy Roberts, Evdokia Anagnostou, Rosanna Weksber. DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders. Journal of autism and developmental disorders. vol 51. issue 10. 2021-09-27. PMID:33394241. here, we examined dna methylation (dnam) in the 1st intron of the oxytocin receptor gene, oxtr, in patients with autism spectrum (asd), attention deficit and hyperactivity (adhd) and obsessive compulsive (ocd) disorders. 2021-09-27 2023-08-13 Not clear
Christina N Rogers Flattery, Daniel J Coppeto, Kiyoshi Inoue, James K Rilling, Todd M Preuss, Larry J Youn. Distribution of brain oxytocin and vasopressin V1a receptors in chimpanzees (Pan troglodytes): comparison with humans and other primate species. Brain structure & function. 2021-09-23. PMID:34482474. here, we used receptor autoradiography to localize oxytocin and vasopressin v1a receptors, oxtr and avpr1a respectively, in seven chimpanzee brains. 2021-09-23 2023-08-13 human
Todd H Ahern, Sara Olsen, Ryan Tudino, Annaliese K Beer. Natural variation in the oxytocin receptor gene and rearing interact to influence reproductive and nonreproductive social behavior and receptor binding. Psychoneuroendocrinology. vol 128. 2021-09-16. PMID:33839431. in this study, we manipulated rearing (biparental versus dam-only), genotyped the intronic nt213739 single nucleotide polymorphism (snp) of the oxytocin receptor gene (oxtr), and then assessed how each factor and their interaction related to reciprocal interactions and partner preference in male and female adult prairie voles. 2021-09-16 2023-08-13 human
Todd H Ahern, Sara Olsen, Ryan Tudino, Annaliese K Beer. Natural variation in the oxytocin receptor gene and rearing interact to influence reproductive and nonreproductive social behavior and receptor binding. Psychoneuroendocrinology. vol 128. 2021-09-16. PMID:33839431. in line with previous literature, c/t animals exhibited higher densities of oxytocin receptor (oxtr) in the striatum (caudoputamen, nucleus accumbens) compared to t/t subjects. 2021-09-16 2023-08-13 human