| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsung-Chih Tsai, Yi-Syuan Fang, Yu-Chieh Hung, Ling-Chien Hung, Kuei-Sen Hs. A dorsal CA2 to ventral CA1 circuit contributes to oxytocinergic modulation of long-term social recognition memory. Journal of biomedical science. vol 29. issue 1. 2022-07-10. PMID:35811321. |
we previously reported that oxytocin (oxt) receptor (oxtr) signaling in the ca2/ca3a of dorsal hippocampus is essential to promote the persistence of long-term srm, yet how the endogenous oxt system influences ca2 outputs to regulate long-term srm formation remains unclear. |
2022-07-10 |
2023-08-14 |
Not clear |
| Lindsey M Biggs, Elizabeth A D Hammoc. Oxytocin via oxytocin receptor excites neurons in the endopiriform nucleus of juvenile mice. Scientific reports. vol 12. issue 1. 2022-07-06. PMID:35794163. |
based on high levels of oxtr ligand binding in epn, we hypothesized that oxytocin application would modulate activity in these cells as measured by whole-cell patch-clamp electrophysiology. |
2022-07-06 |
2023-08-14 |
mouse |
| Michelle Jin Yee Neoh, Peipei Setoh, Andrea Bizzego, Moses Tandiono, Jia Nee Foo, Albert Lee, Marc H Bornstein, Gianluca Esposit. Gene-Environment Interactions in Face Categorization: Oxytocin Receptor Genotype x Childcare Experience Shortens Reaction Time. Frontiers in psychology. vol 13. 2022-06-27. PMID:35756198. |
this study investigated how oxytocin receptor gene (oxtr) genotypes and childcare experience interacted to regulate face categorization in adults. |
2022-06-27 |
2023-08-14 |
human |
| Miriam Saiz-Rodríguez, Cecilia Gil-Polo, Mónica Diez-Fairen, Saul-Indra Martinez-Horta, Frederic Sampedro Santalo, Sara Calvo, Esther Alonso-García, Esther Riñones-Mena, Laura Aguado, Natividad Mariscal, Ignacio Muñoz-Siscart, Dolores Piñeiro, Jessica Rivadeneyra, Esther Cub. Polymorphisms in the oxytocin receptor and their association with apathy and impaired social cognition in Huntington's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-06-21. PMID:35725858. |
genetic variation of oxytocin receptor (oxtr) might interact in the etiology and development of several impaired social behaviors. |
2022-06-21 |
2023-08-14 |
Not clear |
| Yuling Li, Yuan Wang, Xin Guan, Jingyan Yue, Hanjing Emily Wu, Shiqian Zhen, Shu-Chang He, Xiang-Yang Zhan. Genotype-genotype interactions of the OXTR gene polymorphisms are associated with self-reported daytime dysfunction, sleep latency and personal distress. Journal of sleep research. 2022-06-16. PMID:35706410. |
the objective of this study was to examine the main and genotype-genotype interactive effects of the oxytocin receptor gene (oxtr) polymorphisms on sleep quality. |
2022-06-16 |
2023-08-14 |
human |
| Hannah M Heseding, Kirsten Jahn, Christian K Eberlein, Jelte Wieting, Hannah B Maier, Phileas J Proskynitopoulos, Alexander Glahn, Stefan Bleich, Helge Frieling, Maximilian Dees. Distinct promoter regions of the oxytocin receptor gene are hypomethylated in Prader-Willi syndrome and in Prader-Willi syndrome associated psychosis. Translational psychiatry. vol 12. issue 1. 2022-06-10. PMID:35688807. |
recent studies have pointed out altered methylation patterns of the oxytocin receptor gene (oxtr) in various psychiatric disorders, including psychosis. |
2022-06-10 |
2023-08-14 |
human |
| Stephanie Cahill, Tarani Chandola, Reinmar Hage. Genetic Variants Associated With Resilience in Human and Animal Studies. Frontiers in psychiatry. vol 13. 2022-06-07. PMID:35669264. |
further, for oprm1, oxtr (oxytocin receptor), crhr1 (corticotropin-releasing hormone receptor 1), comt (catechol-o-methyltransferase), bdnf (brain-derived neurotrophic factor), apoe (apolipoprotein e), and slc6a4 (solute carrier family 6 member 4), the same allele was associated with resilience across divergent resilience definitions, which suggests these genes may therefore provide a starting point for further research examining commonality in resilience pathways. |
2022-06-07 |
2023-08-14 |
human |
| Birgit Ludwig, Laura Carlberg, Klemens Kienesberger, Patrick Swoboda, Marleen M M Swoboda, Alexandra Bernegger, Romina Koller, Michelle Inaner, Monika Fuxjäger, Melanie Zotter, Nicolas Schmelzle, Birgit Senft, Lisa Meisner, Daniela Fischer-Hansal, Jasmin Huber, Silvia Schoenthaler, Nestor D Kapusta, Helmuth Haslacher, Martin Aigner, Andreas Weinhaeusel, Siegfried Kasper, Alexandra Schosse. Oxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients. BMC psychiatry. vol 22. issue 1. 2022-06-07. PMID:35672748. |
both preclinical and clinical studies point to an increased methylation status of the oxytocin receptor (oxtr) promoter region with concomitant deficits in social, cognitive and emotional functioning. |
2022-06-07 |
2023-08-14 |
Not clear |
| Vincenzo Paolo Senese, Kazuyuki Shinohara, Paola Venuti, Marc H Bornstein, Vittorio Rosanio, Carla Nasti, Michelle Jin-Yee Neoh, Marzia Maresca, Gianluca Esposit. The Interaction Effect of Parental Rejection and Oxytocin Receptor Gene Polymorphism on Depression: A Cross-Cultural Study in Non-Clinical Samples. International journal of environmental research and public health. vol 19. issue 9. 2022-05-14. PMID:35564961. |
the present study aimed to investigate gene-environment interaction effects between parental rejection (maternal and paternal) and oxytocin receptor (oxtr) gene polymorphisms (rs53576 and rs2254298) on depressive symptoms in adults in different cultural contexts. |
2022-05-14 |
2023-08-13 |
Not clear |
| Jesus D Penaloza Aponte, Karen A Scott, Dominique N Johnson, Caeley M Reever, Justin A Smith, Guillaume de Lartigue, Annette D de Kloet, Eric G Kraus. Gastrointestinal mechanosensation affects the activity of prefrontal cortical neurons mediating social behavior in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554409. |
oxytocin is a neuropeptide that shapes the perception of social stimuli by activating the oxytocin receptor (oxtr). |
2022-05-13 |
2023-08-13 |
mouse |
| Karolina Pierzynowska, Magdalena Żabińska, Lidia Gaffke, Zuzanna Cyske, Grzegorz Węgrzy. Changes in expression of signal transduction-related genes, and formation of aggregates of GPER1 and OXTR receptors in mucopolysaccharidosis cells. European journal of cell biology. vol 101. issue 3. 2022-05-10. PMID:35537249. |
when studying membrane estrogen receptor 1 (gper1) and oxytocin receptor (oxtr) in more detail, we unexpectedly found formation of aggregates of gper1 in mps i, and those of oxtr in both mps i and mps ii cells. |
2022-05-10 |
2023-08-13 |
Not clear |
| Justin A Smith, Sophia A Eikenberry, Karen A Scott, Caitlin B Harrison, Guillaume de Lartigue, Annette D de Kloet, Eric G Kraus. Oxytocin and cardiometabolic interoception: Knowing oneself affects ingestive and social behaviors. Appetite. 2022-04-21. PMID:35447163. |
oxytocin is an evolutionarily conserved peptide that regulates attention to exteroceptive and interoceptive stimuli in a social environment by functioning in the brain as a modulatory neuropeptide to control social behavior, but also in the periphery as a hormone acting at oxytocin receptors (oxtr) expressed in the heart, gut, and peripheral ganglia. |
2022-04-21 |
2023-08-13 |
Not clear |
| Mengmeng Wang, Xuqin Guo, Man Yang, Yawen Zhang, Fanyi Meng, Yinshuang Chen, Mengxi Chen, Tian Qiu, Jiawei Li, Zhi Li, Qi Zhang, Fang Xu, Haiyang Zhang, Weipeng Wan. Synergistic antitumor activity of 5-fluorouracil and atosiban against microsatellite stable colorectal cancer through restoring GATA3. Biochemical pharmacology. 2022-04-03. PMID:35367196. |
since the sensitivity of 5-fu is negatively correlated with oxytocin receptor (oxtr) expression in mss crc cell lines, our current study aimed to investigate the synergistic antitumor activity of 5-fu combined with atosiban, an antagonist of oxtr. |
2022-04-03 |
2023-08-13 |
Not clear |
| Jaroslav Rokicki, Tobias Kaufmann, Ann-Marie G de Lange, Dennis van der Meer, Shahram Bahrami, Alina M Sartorius, Unn K Haukvik, Nils Eiel Steen, Emanuel Schwarz, Dan J Stein, Terje Nærland, Ole A Andreassen, Lars T Westlye, Daniel S Quintan. Oxytocin receptor expression patterns in the human brain across development. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-03-29. PMID:35347267. |
oxytocin plays a vital role in social behavior and homeostatic processes, with animal models indicating that oxytocin receptor (oxtr) expression patterns in the brain influence behavior and physiology. |
2022-03-29 |
2023-08-13 |
human |
| Hyun Seo Lee, Aeran Kwon, Seung Hwan Le. Oxytocin receptor genes moderate BDNF epigenetic methylation by childhood trauma. Journal of affective disorders. 2022-03-22. PMID:35314247. |
this study investigated the interaction effect of childhood traumatic experience and epigenetic methylation of brain-derived neurotrophic factor (bdnf) and a possible moderating effect of oxytocin receptor (oxtr) gene rs53576. |
2022-03-22 |
2023-08-13 |
Not clear |
| Lauren E Granata, Alissa Valentine, Jason L Hirsch, Heather C Brenhous. Infant ultrasonic vocalizations predict adolescent social behavior in rats: Effects of early life adversity. Developmental psychobiology. vol 64. issue 3. 2022-03-21. PMID:35312059. |
adolescent oxytocin receptor (oxtr) and arginine-vasopressin receptor 1a mrna were measured in the pfc. |
2022-03-21 |
2023-08-13 |
rat |
| Anja Gemmer, Kristina Mirkes, Lukas Anneser, Tim Eilers, Caroline Kibat, Ajay Mathuru, Soojin Ryu, Erin Schuma. Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio). Scientific reports. vol 12. issue 1. 2022-03-13. PMID:35279678. |
in this study we investigated the role of the two oxytocin receptors, oxtr and oxtrl, in the development and maintenance of social preference and shoaling behavior in 2- to 8-week-old zebrafish. |
2022-03-13 |
2023-08-13 |
zebrafish |
| Anja Gemmer, Kristina Mirkes, Lukas Anneser, Tim Eilers, Caroline Kibat, Ajay Mathuru, Soojin Ryu, Erin Schuma. Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio). Scientific reports. vol 12. issue 1. 2022-03-13. PMID:35279678. |
using crispr/cas9 mediated oxtr and oxtrl knock-out fish, we found that the development of social preference is accelerated if one of the oxytocin receptors is knocked-out and that the knock-out fish reach significantly higher levels of social preference. |
2022-03-13 |
2023-08-13 |
zebrafish |
| Linlin He, Jinting Liu, Yuhe Fan, Junhui Leng, Quanhe Wang, Cuimei Yang, Rui Zhang, Wenxuan Guo, Jieting Zhang, Pingyuan Gon. The OXTR rs53576 impacts moral permissibility of attempted but failed harms in populations of students and prisoners. Social cognitive and affective neuroscience. 2022-03-11. PMID:35275212. |
based on these findings, recent studies have examined the association between the oxytocin receptor gene (oxtr) and outcome-based moral judgment with sacrificial dilemmas (e.g. |
2022-03-11 |
2023-08-13 |
Not clear |
| Jane Kohlhoff, Sara Cibralic, David Hawes, Valsamma Eape. Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review. Neuroscience and biobehavioral reviews. 2022-02-12. PMID:35149102. |
oxytocin receptor gene (oxtr) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review. |
2022-02-12 |
2023-08-13 |
Not clear |