| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian-Wen Ruan, Jie-Fang Zhao, Xue-Li Li, Bo Liao, Li Pan, Ke-Zhang Zhu, Qi-Miao Feng, Jin-Xin Liu, Zi-E Yu, Jia Song, Hai Wang, Zheng Li. Characterizing the Neutrophilic Inflammation in Chronic Rhinosinusitis With Nasal Polyps. Frontiers in cell and developmental biology. vol 9. 2022-01-03. PMID:34977034. |
the 95th percentile of tissue neutrophil numbers in control subjects was selected as a cut-off to define neutrophil-high (neu-high) or neutrophil-low (neu-low) nasal polyps (nps). |
2022-01-03 |
2023-08-13 |
human |
| Hussein Akel, Ildikó Csóka, Rita Ambrus, Alexandra Bocsik, Ilona Gróf, Mária Mészáros, Anikó Szecskó, Gábor Kozma, Szilvia Veszelka, Mária A Deli, Zoltán Kónya, Gábor Katon. In Vitro Comparative Study of Solid Lipid and PLGA Nanoparticles Designed to Facilitate Nose-to-Brain Delivery of Insulin. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948054. |
encapsulating insulin into chitosan-coated nps can be beneficial for ensuring structural stability, enhancing nasal absorption, followed by sustained drug release. |
2021-12-24 |
2023-08-13 |
human |
| Brian J Lipworth, Rory Cha. The Choice of Biologics in Patients with Severe Chronic Rhinosinusitis with Nasal Polyps. The journal of allergy and clinical immunology. In practice. vol 9. issue 12. 2021-12-11. PMID:34332173. |
an indirect comparison from phase 3 placebo-controlled trials has shown relative improvements in the coprimary end point of nasal polyp score (nps) ranging from a 15% reduction (-0.8 units) with mepolizumab, 18% with omalizumab (-1.14 units), and 35% (-2.06 units) with dupilumab. |
2021-12-11 |
2023-08-13 |
Not clear |
| Joseph K Han, Claus Bachert, Stella E Lee, Claire Hopkins, Enrico Heffler, Peter W Hellings, Anju T Peters, Siddhesh Kamat, Diane Whalley, Shanshan Qin, Lauren Nelson, Shahid Siddiqui, Asif H Khan, Yongtao Li, Leda P Mannent, Isabelle Guillemin, Chien-Chia Chuan. Estimating Clinically Meaningful Change of Efficacy Outcomes in Inadequately Controlled Chronic Rhinosinusitis with Nasal Polyposis. The Laryngoscope. 2021-12-01. PMID:34850966. |
clinical trials of biologics to treat chronic rhinosinusitis with nasal polyposis (crswnp) have evaluated objective outcomes (e.g., university of pennsylvania smell identification test [upsit], nasal polyps score [nps], and computed tomography lund-mackay score [ct-lmk]) and patient-reported symptoms (e.g., nasal congestion/obstruction [nc], loss of smell [los], and total symptom score [tss]). |
2021-12-01 |
2023-08-13 |
Not clear |
| Maria E Di Cicco, Francesca Bizzoco, Elena Morelli, Veronica Seccia, Vincenzo Ragazzo, Diego G Peroni, Pasquale Comberiat. Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition. Children (Basel, Switzerland). vol 8. issue 11. 2021-11-29. PMID:34828710. |
nasal polyps (nps) are benign inflammatory masses causing chronic nasal obstruction, usually associated with underlying chronic rhinosinusitis (crs), which are rarely reported in childhood. |
2021-11-29 |
2023-08-13 |
Not clear |
| Yara Zoabi, Fidan Rahimli Alekberli, Yael Minai-Fleminger, Ron Eliashar, Francesca Levi-Schaffe. CD48 Expression on Eosinophils in Nasal Polyps of Chronic Rhinosinusitis Patients. International archives of allergy and immunology. vol 182. issue 10. 2021-11-12. PMID:33910197. |
based on current knowledge, the infiltration of mast cells and eosinophils in nasal polyps (nps) plays an important role. |
2021-11-12 |
2023-08-13 |
Not clear |
| Rory Chan, Brian Lipwort. Impact of nasal polyps on endotype and phenotype in patients with moderate to severe asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. vol 127. issue 5. 2021-11-10. PMID:34153444. |
nasal polyps (nps) are a common comorbidity of asthma. |
2021-11-10 |
2023-08-13 |
Not clear |
| Thawaree Nukpook, Tipaya Ekalaksananan, Tohru Kiyono, Pornthep Kasemsiri, Watchareporn Teeramatwanich, Patravoot Vatanasapt, Surachat Chaiwiriyakul, Piti Ungarreevittaya, Jureeporn Kampan, Kanha Muisuk, Chamsai Pienton. Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas. Scientific reports. vol 11. issue 1. 2021-11-02. PMID:34429452. |
to better understand the pathogenesis of nasal polyps (nps) and sinonasal inverted papillomas (sips), we aimed to establish cell lines from fresh tissues of nps and sips and characterize them. |
2021-11-02 |
2023-08-13 |
Not clear |
| Natália N Ferreira, Sara Granja, Fernanda I Boni, Fabíola G Prezotti, Leonardo M B Ferreira, Beatriz S F Cury, Rui M Reis, Fátima Baltazar, Maria Palmira D Gremiã. Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route. Drug delivery and translational research. vol 10. issue 6. 2021-11-01. PMID:32683647. |
mucoadhesive nanoparticles (nps) based on poly(lactic-co-glycolic acid) (plga) and oligomeric chitosan (ocs) were designed as a rational strategy and potential platform to co-deliver alpha-cyano-4-hydroxycinnamic acid (chc) and the monoclonal antibody cetuximab (ctx) into the brain, by nasal administration. |
2021-11-01 |
2023-08-13 |
Not clear |
| Won Woo Ban, Yoon Jin Lee, Sang Han Lee, Jae Yeop Jung, Byoung Joon Bae. Expression of Estrogen Receptor-alpha in Nasal Polyps and the Effects of Dexamethasone on Estrogen Receptor-alpha Expression in RPMI 2650 Cells. Journal of Korean medical science. vol 35. issue 50. 2021-11-01. PMID:33372422. |
studies have reported that epithelial cell proliferation may be involved in the pathogenesis of nasal polyps (nps). |
2021-11-01 |
2023-08-13 |
Not clear |
| Mahsa Ghasemzad, Seyed Mohammad Reza Hashemian, Arash Memarnejadian, Iman Akbarzadeh, Nikoo Hossein-Khannazer, Massoud Vosoug. The nano-based theranostics for respiratory complications of COVID-19. Drug development and industrial pharmacy. 2021-10-29. PMID:34666567. |
inhalable nps could be delivered through nasal sprays, inhalers, and nebulizers. |
2021-10-29 |
2023-08-13 |
Not clear |
| A J Gadenstaetter, C D Mayer, L D Landegge. Nasopharyngeal versus nasal swabs for detection of SARS-CoV-2: a systematic review. Rhinology. vol 59. issue 5. 2021-10-26. PMID:34666340. |
however, numerous studies have recently demonstrated the advantages of alternative nasal specimen collection approaches over nps specifically for covid-19 diagnosis. |
2021-10-26 |
2023-08-13 |
Not clear |
| A J Gadenstaetter, C D Mayer, L D Landegge. Nasopharyngeal versus nasal swabs for detection of SARS-CoV-2: a systematic review. Rhinology. vol 59. issue 5. 2021-10-26. PMID:34666340. |
publications investigating nps and at least one other form of nasal specimen collection in combination with rt-pcr for viral detection in the context of covid-19 were assessed. |
2021-10-26 |
2023-08-13 |
Not clear |
| Sung-Woo Cho, Dong-Young Kim, Sungmi Choi, Sungho Won, Hye-Ryun Kang, Hana Y. Microbiome profiling of uncinate tissue and nasal polyps in patients with chronic rhinosinusitis using swab and tissue biopsy. PloS one. vol 16. issue 4. 2021-09-17. PMID:33831071. |
chronic rhinosinusitis (crs) is characterized according to the presence or absence of nasal polyps (nps) and displays nasal microbiota dysbiosis. |
2021-09-17 |
2023-08-13 |
Not clear |
| b' Aleksandar Peri\\xc4\\x87, Marko Stoiljkov, Danijela \\xc4\\x90oki\\xc4\\x87, Biserka Vukomanovi\\xc4\\x87 \\xc4\\x90ur\\xc4\\x91evi\\xc4\\x8. Epithelial Squamous Metaplasia and Dysplasia in Inflammatory Nasal Polyps: An Observational Study. Ear, nose, & throat journal. vol 100. issue 2. 2021-09-02. PMID:31309847.' |
the presence of squamous metaplasia and dysplasia on the mucosal surface of nasal polyps (nps) represents different manifestations of epithelial atypia. |
2021-09-02 |
2023-08-13 |
Not clear |
| Ting Zhang, Yong Zhou, Bo You, Yiwen You, Yongbing Yan, Jie Zhang, Yinyin Pei, Wei Zhang, Jing Che. miR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition by Targeting CDK6 in Nasal Polyps. American journal of rhinology & allergy. vol 35. issue 2. 2021-08-18. PMID:32623901. |
although aberrant expression of mirnas and occurrence of emt were previously reported in nasal polyps (nps), the role of mir-30a-5p in emt of nps is still remains unclear. |
2021-08-18 |
2023-08-13 |
human |
| Mengjie Sun, Di Qin, Pengsheng Fan, Xiguang Chen, Ya Li. Chitosan-centered nanosystems as sustained therapeutics for allergic rhinitis intervention: Inhibition of histamine-induced cascades. Journal of controlled release : official journal of the Controlled Release Society. vol 335. 2021-08-11. PMID:34087247. |
in this regard, kt incorporated and ctz decorated hydroxybutyl chitosan nanoparticles (k ⊂ ch nps) were fabricated as nasal adaptive sequential release dual drug system for long-term ar therapy. |
2021-08-11 |
2023-08-13 |
Not clear |
| Ahmet Oguzhan Bicakci, Pei-Ling Tsai, Evelyn Kahl, Dana Mayer, Markus Fend. Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning. Pharmaceuticals (Basel, Switzerland). vol 14. issue 7. 2021-08-09. PMID:34358069. |
in the second experiment, c57bl/6j mice were tested in the t-maze after nasal administration of nps. |
2021-08-09 |
2023-08-13 |
mouse |
| Ahmet Oguzhan Bicakci, Pei-Ling Tsai, Evelyn Kahl, Dana Mayer, Markus Fend. Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning. Pharmaceuticals (Basel, Switzerland). vol 14. issue 7. 2021-08-09. PMID:34358069. |
finally, the effect of nasal nps on locomotor activity was evaluated. |
2021-08-09 |
2023-08-13 |
mouse |
| Ahmet Oguzhan Bicakci, Pei-Ling Tsai, Evelyn Kahl, Dana Mayer, Markus Fend. Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning. Pharmaceuticals (Basel, Switzerland). vol 14. issue 7. 2021-08-09. PMID:34358069. |
nasal nps administration facilitated reversal learning and supported an allocentric learning strategy without affecting acquisition of the task or locomotor activity. |
2021-08-09 |
2023-08-13 |
mouse |