| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ximing Bao, Bin Liu, Yongquan Jiang, Tingting Feng, Wanxin Cao, Jiali Shi, Yiming Jiang, Xiaorui Chen, Jie Yang, Jiping Li, Zheng Zho. Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage. Immunity, inflammation and disease. vol 11. issue 2. 2023-02-25. PMID:36840491. |
however, the role of ros and senp3 in the formation of nasal polyps (nps) remains unclear. |
2023-02-25 |
2023-08-14 |
Not clear |
| Kasper Daugaard Larsen, Mads Mose Jensen, Anne-Sophie Homøe, Elisabeth Arndal, Grethe Badsberg Samuelsen, Anders Koch, Xiaohui Chen Nielsen, Preben Homøe, Tobias Todse. Head-to-Head Comparison of Nasopharyngeal, Oropharyngeal and Nasal Swabs for SARS-CoV-2 Molecular Testing. Diagnostics (Basel, Switzerland). vol 13. issue 2. 2023-01-21. PMID:36673094. |
we conducted a head-to-head prospective study to compare the sensitivity of nps, ops and nasal swabs specimens for sars-cov-2 molecular testing. |
2023-01-21 |
2023-08-14 |
human |
| Kasper Daugaard Larsen, Mads Mose Jensen, Anne-Sophie Homøe, Elisabeth Arndal, Grethe Badsberg Samuelsen, Anders Koch, Xiaohui Chen Nielsen, Preben Homøe, Tobias Todse. Head-to-Head Comparison of Nasopharyngeal, Oropharyngeal and Nasal Swabs for SARS-CoV-2 Molecular Testing. Diagnostics (Basel, Switzerland). vol 13. issue 2. 2023-01-21. PMID:36673094. |
all participants had ops, nps and nasal swab performed by an otorhinolaryngologist. |
2023-01-21 |
2023-08-14 |
human |
| Peng Jin, Qiuliang Zhao, Yiran Zang, Qinqin Zhang, Chaofan Shen, Hongyang Zhang, Hongping Zhang, Lili Zh. A Google Trends analysis revealed global public interest and awareness of nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2023-01-15. PMID:36642736. |
nasal polyps (nps) is a common upper airway inflammatory disorder with a huge negative burden on both the quality of life and costs to patients. |
2023-01-15 |
2023-08-14 |
Not clear |
| Vaishnavi Gattani, Shilpa Dawr. Development of favipiravir loaded PLGA nanoparticles entrapped in in-situ gel for treatment of Covid-19 via nasal route. Journal of drug delivery science and technology. 2022-12-19. PMID:36530548. |
moreover, these nps were entrapped in thermosensitive gel to increase the permeation through nasal route. |
2022-12-19 |
2023-08-14 |
Not clear |
| Geng-He Chang, Pei-Rung Yang, Yu-Ching Cheng, Ke-Hsin Hsu, Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Cheng-Ming Hsu, Ming-Shao Tsai, Yao-Te Tsai, Pey-Jium Chan. Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study. BMC complementary medicine and therapies. vol 22. issue 1. 2022-11-29. PMID:36447209. |
to date, treating nasal polyps (nps) is still a medical challenge. |
2022-11-29 |
2023-08-14 |
Not clear |
| Geng-He Chang, Pei-Rung Yang, Yu-Ching Cheng, Ke-Hsin Hsu, Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Cheng-Ming Hsu, Ming-Shao Tsai, Yao-Te Tsai, Pey-Jium Chan. Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study. BMC complementary medicine and therapies. vol 22. issue 1. 2022-11-29. PMID:36447209. |
however, we have developed an innovative therapy using licorice extract (le: glycyrrhiza glabra) to treat rhinitis and sinusitis via nasal irrigation and have discovered that it significantly affects treatment of nps. |
2022-11-29 |
2023-08-14 |
Not clear |
| Yih-Jeng Tsai, Yu-Ting Hsu, Ming-Chieh Ma, Chun-Kuang Wu, Sheng-Dean Luo, Wen-Bin W. Transcriptomic Analysis of Genes Associated with Oxidative Stress in Chronic Rhinosinusitis Patients with Nasal Polyps: Identifying Novel Genes Involved in Nasal Polyposis. Antioxidants (Basel, Switzerland). vol 11. issue 10. 2022-10-27. PMID:36290622. |
the distribution and expression of 4-hydroxynonenal and 3-nitrotyrosine as markers of oxidative stress-which is represented by lipid peroxidation and the protein nitration of tyrosine residues in crswnp nasal polyps (nps)-were more apparently increased than those found in the control nasal mucosae, as determined by immunohistochemistry (ihc). |
2022-10-27 |
2023-08-14 |
Not clear |
| Federica De Gaetano, Nicola d'Avanzo, Antonia Mancuso, Anna De Gaetano, Giuseppe Paladini, Francesco Caridi, Valentina Venuti, Donatella Paolino, Cinzia Anna Ventur. Chitosan/Cyclodextrin Nanospheres for Potential Nose-to-Brain Targeting of Idebenone. Pharmaceuticals (Basel, Switzerland). vol 15. issue 10. 2022-10-27. PMID:36297318. |
furthermore, fourier transform infrared spectroscopy (ft-ir) demonstrated the ability of cs nps to interact with the excised bovine nasal mucosa, improving the permeation of the drug and potentially favoring its accumulation in the brain. |
2022-10-27 |
2023-08-14 |
cattle |
| Rinada H Hassan, Heba A Gad, Sahar Badr El-Din, Dalia S Shaker, Rania A H Isha. Chitosan Nanoparticles for Intranasal Delivery of Olmesartan Medoxomil: Pharmacokinetic and Pharmacodynamic Perspectives. International journal of pharmaceutics. 2022-10-15. PMID:36243325. |
in this context, the goal of this work was to synthesize chitosan nanoparticles (cs nps) loaded with olm using the ionotropic gelation method to enhance the bioavailability and decrease oral side effects through nasal route. |
2022-10-15 |
2023-08-14 |
rat |
| Rinada H Hassan, Heba A Gad, Sahar Badr El-Din, Dalia S Shaker, Rania A H Isha. Chitosan Nanoparticles for Intranasal Delivery of Olmesartan Medoxomil: Pharmacokinetic and Pharmacodynamic Perspectives. International journal of pharmaceutics. 2022-10-15. PMID:36243325. |
the ability of olm cs nps to permeate efficiently across the nasal mucosa was proven in an ex vivo permeation experiment. |
2022-10-15 |
2023-08-14 |
rat |
| Ahmet Bedir, Abdulkadir Özgür, Mustafa Bakırtaş, Doğukan Özdemir, Dursun Mehmet Mehel, Gökhan Akgül, Mehmet Çeleb. Mucin receptors in chronic rhinosinusitis with nasal polyps. Acta oto-laryngologica. 2022-09-15. PMID:36106988. |
nasal polyps (nps) are non-neoplastic, painless inflammatory lesions of the sino-nasal mucosa. |
2022-09-15 |
2023-08-14 |
Not clear |
| Greg E Davis, Robert S Zeiger, Benjamin Emmanuel, Yen Chung, Trung N Tran, Kristin A Evans, Stephanie Chen, Rohit Katial, James L Kreindler, Joseph Tkac. Systemic Corticosteroid-related Adverse Outcomes and Health Care Resource Utilization and Costs Among Patients with Chronic Rhinosinusitis with Nasal Polyposis. Clinical therapeutics. 2022-09-03. PMID:36057475. |
nasal polyps (nps) develop in 20% to 30% of patients with chronic rhinosinusitis. |
2022-09-03 |
2023-08-14 |
Not clear |
| Yoshihiro Fujiya, Yuki Sato, Yuki Katayama, Shinya Nirasawa, Mikako Moriai, Masachika Saeki, Yuki Yakuwa, Ikumi Kitayama, Koichi Asanuma, Koji Kuronuma, Satoshi Takahash. Viral load may impact the diagnostic performance of nasal swabs in nucleic acid amplification test and quantitative antigen test for SARS-CoV-2 detection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022-08-11. PMID:35953013. |
compared to nasopharyngeal swabs (nps), there has been insufficient evaluation of the diagnostic performance of nasal swabs (ns) for the detection of severe acute respiratory coronavirus 2 (sars-cov-2) in the nucleic acid amplification test (naat) and quantitative sars-cov-2 antigen test (qat). |
2022-08-11 |
2023-08-14 |
Not clear |
| Elena Cantone, Eugenio De Corso, Filippo Ricciardiello, Claudio Di Nola, Giusi Grimaldi, Viviana Allocca, Gaetano Mott. Olfaction Recovery following Dupilumab Is Independent of Nasal Polyp Reduction in CRSwNP. Journal of personalized medicine. vol 12. issue 8. 2022-07-27. PMID:35893310. |
we observed improvement in all clinical outcomes with a significant correlation between vas-ss-i/snot22, whereas we did not find a correlation between nasal polyp score (nps) and ss-i or vas. |
2022-07-27 |
2023-08-14 |
Not clear |
| Carlo Cavaliere, Marco Segatto, Andrea Ciofalo, Andrea Colizza, Antonio Minni, Daniela Messineo, Alessandro Lambiase, Antonio Greco, Marco de Vincentiis, Simonetta Masier. BENRALIZUMAB REDUCES EOSINOPHILS AND INFLAMMATORY MARKERS IN PATIENTS WITH SEVERE EOSINOPHILIC ASTHMA AND CHRONIC RHINOSINUSITIS WITH NASAL POLYPS: A PILOT REAL-LIFE STUDY. Immunology letters. 2022-06-25. PMID:35752279. |
we retrospectively observe 11 patients with severe crswnp and concomitant sea under add-on therapy with benralizumab evaluating symptoms using sino nasal outcome test-22 (snot-22), visual analogue scale (vas), and asthma control test (act) and nasal polyp size by endoscopic and radiological score by nasal polyp score (nps) and lund-mackay score (lms). |
2022-06-25 |
2023-08-14 |
human |
| Tze-Wen Chung, Ting-Ya Wu, Zheng-Yu Siah, Der-Zen Li. Antioxidative NAC-Loaded Silk Nanoparticles with Opening Mucosal Tight Junctions for Nasal Drug Delivery: An In Vitro and In Vivo Study. Pharmaceutics. vol 14. issue 6. 2022-06-24. PMID:35745861. |
using nasal routes to deliver drugs to the brain using multifunctional nanoparticles (nps) to bypass the blood-brain barrier (bbb) might enhance the delivery efficacy. |
2022-06-24 |
2023-08-14 |
Not clear |
| Tze-Wen Chung, Ting-Ya Wu, Zheng-Yu Siah, Der-Zen Li. Antioxidative NAC-Loaded Silk Nanoparticles with Opening Mucosal Tight Junctions for Nasal Drug Delivery: An In Vitro and In Vivo Study. Pharmaceutics. vol 14. issue 6. 2022-06-24. PMID:35745861. |
anti-oxidative n-acetyl-l-cysteine (nac)-loaded silk fibroin (sf/nac) nps are produced, characterized and studied as a potential delivery vehicle for nac delivered to the brain via nasal for both in vitro and in vivo studies. |
2022-06-24 |
2023-08-14 |
Not clear |
| Juan Carlos Vizuet-de-Rueda, Josaphat Miguel Montero-Vargas, Miguel Ángel Galván-Morales, Raúl Porras-Gutiérrez-de-Velasco, Luis M Tera. Current Insights on the Impact of Proteomics in Respiratory Allergies. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628512. |
they include allergic rhinitis (ar), asthma, pollen food allergy syndrome (pfas), aspirin-exacerbated respiratory disease (aerd), and nasal polyps (nps). |
2022-05-28 |
2023-08-13 |
Not clear |
| Claus Bachert, Asif H Khan, Claire Hopkins, Michael S Blaiss, Zachary M Soler, Scott Nash, Shahid Siddiqui, Amy Praestgaard, Yamo Deniz, Paul J Rowe, Juby A Jacob-Nar. Rapid and Continuing Improvements in Nasal Symptoms with Dupilumab in Patients with Severe CRSwNP. Journal of asthma and allergy. vol 15. 2022-05-13. PMID:35548056. |
in the phase 3 sinus-24 (nct02912468) and sinus-52 (nct02898454) studies in adults with severe chronic rhinosinusitis with nasal polyps (crswnp), dupilumab significantly improved the co-primary endpoints of change from baseline to week 24 in nasal polyp score (nps) and nasal congestion/obstruction (nc) vs placebo on background intranasal corticosteroids (standard of care [soc]). |
2022-05-13 |
2023-08-13 |
Not clear |