| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie A Poposki, Aiko I Klingler, Whitney W Stevens, Anju T Peters, Kathryn E Hulse, Leslie C Grammer, Robert P Schleimer, Kevin C Welch, Stephanie S Smith, Douglas M Sidle, David B Conley, Bruce K Tan, Robert C Kern, Atsushi Kat. Proprotein convertases generate a highly functional heterodimeric form of thymic stromal lymphopoietin in humans. The Journal of allergy and clinical immunology. vol 139. issue 5. 2017-08-18. PMID:27744031. |
thymic stromal lymphopoietin (tslp) is known to be elevated and truncated in nasal polyps (nps) of patients with chronic rhinosinusitis and might play a significant role in type 2 inflammation in this disease. |
2017-08-18 |
2023-08-13 |
Not clear |
| Justin A Edward, Mrinmoy Sanyal, Wei Le, Ethan Soudry, Vijay R Ramakrishnan, Dawn T Bravo, Alan L Nguyen, David Zarabanda, Todd T Kingdom, Peter H Hwang, C Garrison Fathman, Jayakar V Naya. Selective expansion of human regulatory T cells in nasal polyps, and not adjacent tissue microenvironments, in individual patients exposed to steroids. Clinical immunology (Orlando, Fla.). vol 179. 2017-08-18. PMID:28279811. |
severe forms of chronic rhinosinusitis (crs), a common upper airway inflammatory disorder, are associated with nasal polyps (nps). |
2017-08-18 |
2023-08-13 |
human |
| Dong-Young Kim, Sun Hye Lee, Roderick G Carter, Atsushi Kato, Robert P Schleimer, Seong H Ch. A Recently Established Murine Model of Nasal Polyps Demonstrates Activation of B Cells, as Occurs in Human Nasal Polyps. American journal of respiratory cell and molecular biology. vol 55. issue 2. 2017-06-30. PMID:27163839. |
our laboratory recently established a mouse model of nasal polyps (nps) and investigated similarities and differences between this mouse model and human nps. |
2017-06-30 |
2023-08-13 |
mouse |
| Dong-Young Kim, Sun Hye Lee, Roderick G Carter, Atsushi Kato, Robert P Schleimer, Seong H Ch. A Recently Established Murine Model of Nasal Polyps Demonstrates Activation of B Cells, as Occurs in Human Nasal Polyps. American journal of respiratory cell and molecular biology. vol 55. issue 2. 2017-06-30. PMID:27163839. |
similar to human nps, there were significant increases in gene expression of inflammatory cell markers, such as cd19, cd138, cd11c, and mast cell protease-6 in nasal tissue samples of the np group compared with those of the control group. |
2017-06-30 |
2023-08-13 |
mouse |
| Changzhi Sun, Hong Ouyang, Renzhong Lu. Distinct characteristics of nasal polyps with and without eosinophilia. Brazilian journal of otorhinolaryngology. vol 83. issue 1. 2017-05-03. PMID:27166273. |
eosinophilic and noneosinophilic nasal polyps (nps) are different subtypes of nps and require different treatment methods. |
2017-05-03 |
2023-08-13 |
Not clear |
| Zhuoping Liang, Ting Yang, Wei Xu, Ying Huang, Liang Jiang, Zedeng Yin, Gang Qi. The role of dendritic cells in immune regulation of nasal polyps. Histology and histopathology. vol 32. issue 1. 2017-04-14. PMID:27117506. |
nasal polyps (nps) are caused by a variety of immune cells and inflammatory cells. |
2017-04-14 |
2023-08-13 |
Not clear |
| Ida Genta, Claudia Colonna, Bice Conti, Paolo Caliceti, Stefano Salmaso, Pietro Speziale, Giampiero Pietrocola, Enrica Chiesa, Tiziana Modena, Rossella Dorat. CNA-loaded PLGA nanoparticles improve humoral response againstS. aureus-mediated infections in a mouse model: subcutaneous vs. nasal administration strategy. Journal of microencapsulation. vol 33. issue 8. 2017-04-13. PMID:27845595. |
"in vivo" immunogenicity studies were performed on mice: immunisation protocols encompassed subcutaneous and intranasal administration of cna19 formulated as nanoparticles (nps) and furthermore, cna19-loaded nps formulated in a set-up thermosetting chitosan-β-glycerolphosphate (chitosan-β-gp) solution for intranasal route in order to extend antigen exposure to nasal mucosa. |
2017-04-13 |
2023-08-13 |
mouse |
| Maryam Amirnasr, Tannan Fallah Tafti, Mojtaba Sankian, Abdorrahim Rezaei, Mohsen Tafaghod. Immunization against HTLV-I with chitosan and tri-methylchitosan nanoparticles loaded with recombinant env23 and env13 antigens of envelope protein gp46. Microbial pathogenesis. vol 97. 2017-03-27. PMID:27235335. |
the immunogenicity of nps loaded with antigens was studied after nasal and subcutaneous immunization in mice. |
2017-03-27 |
2023-08-13 |
mouse |
| T Panogeorgou, E Tserbini, S Filou, D H Vynios, S S Naxakis, T A Papadas, P D Goumas, N S Mastronikoli. Hyaluronan synthases and hyaluronidases in nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 273. issue 7. 2017-02-21. PMID:26661071. |
nasal polyps (nps) are benign lesions of nasal and paranasal sinuses mucosa affecting 1-4 % of all adults. |
2017-02-21 |
2023-08-13 |
Not clear |
| T Panogeorgou, E Tserbini, S Filou, D H Vynios, S S Naxakis, T A Papadas, P D Goumas, N S Mastronikoli. Hyaluronan synthases and hyaluronidases in nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 273. issue 7. 2017-02-21. PMID:26661071. |
the development of nps is caused by the hyperplasia of nasal or paranasal sinuses mucosa, and edema of extracellular matrix. |
2017-02-21 |
2023-08-13 |
Not clear |
| T Panogeorgou, E Tserbini, S Filou, D H Vynios, S S Naxakis, T A Papadas, P D Goumas, N S Mastronikoli. Hyaluronan synthases and hyaluronidases in nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 273. issue 7. 2017-02-21. PMID:26661071. |
the purpose of the present study was the investigation, in nps and normal nasal mucosa (nm), of the expression of the wild-type and alternatively spliced forms of hyaluronidases, their immunolocalization, and the expression of ha synthases to examine the isoform(s) responsible for the increased amounts of ha in nps. |
2017-02-21 |
2023-08-13 |
Not clear |
| Sandra Jesus, Edna Soares, João Costa, Gerrit Borchard, Olga Borge. Immune response elicited by an intranasally delivered HBsAg low-dose adsorbed to poly-ε-caprolactone based nanoparticles. International journal of pharmaceutics. vol 504. issue 1-2. 2017-01-19. PMID:26976502. |
nasal vaccination using polymeric nanoparticles (nps) constitutes a valid approach to this issue. |
2017-01-19 |
2023-08-13 |
mouse |
| Sandra Jesus, Edna Soares, João Costa, Gerrit Borchard, Olga Borge. Immune response elicited by an intranasally delivered HBsAg low-dose adsorbed to poly-ε-caprolactone based nanoparticles. International journal of pharmaceutics. vol 504. issue 1-2. 2017-01-19. PMID:26976502. |
the intranasal (in) administration of 3 different doses of hbsag (1.5 μg, 5 μg and 10 μg) adsorbed on a fixed amount of pcl/chitosan nps (1614 μg) generated identical titers of serum anti-hbsag igg and anti-hbsag siga in mice nasal secretions. |
2017-01-19 |
2023-08-13 |
mouse |
| Dilip Pawar, K S Jaganatha. Mucoadhesive glycol chitosan nanoparticles for intranasal delivery of hepatitis B vaccine: enhancement of mucosal and systemic immune response. Drug delivery. vol 23. issue 1. 2016-10-24. PMID:24825494. |
during in vivo studies, gc nps showed the lowest nasal clearance rate and better mucosal uptake when compared with chitosan (cs) nps. |
2016-10-24 |
2023-08-13 |
mouse |
| Chandrakantsing V Pardeshi, Veena S Belgamwa. Controlled synthesis of N,N,N-trimethyl chitosan for modulated bioadhesion and nasal membrane permeability. International journal of biological macromolecules. vol 82. 2016-10-13. PMID:26562548. |
increased bioadhesion of tmc nps over cht nps can be attributed to the strong electrostatic interactions between cationic amino groups with anionic sialic and sulfonic acid moieties contained in the mucin of the nasal mucus. |
2016-10-13 |
2023-08-13 |
cattle |
| Chandrakantsing V Pardeshi, Veena S Belgamwa. Controlled synthesis of N,N,N-trimethyl chitosan for modulated bioadhesion and nasal membrane permeability. International journal of biological macromolecules. vol 82. 2016-10-13. PMID:26562548. |
ex vivo permeation studies executed on excised cattle nasal mucosa illustrated improved permeability of tmc nps over cht nps. |
2016-10-13 |
2023-08-13 |
cattle |
| Li Xiao, Lei Jia, Yannan Zhang, Sifei Yu, Xingmei Wu, Binyan Yang, Huabin Li, Changyou W. Human IL-21+IFN-γ+CD4+ T cells in nasal polyps are regulated by IL-12. Scientific reports. vol 5. 2016-08-02. PMID:26239551. |
in the previous study, we found that the levels of il-21 in nasal polyps (nps) were significantly increased and associated with polyp size and recurrence. |
2016-08-02 |
2023-08-13 |
human |
| Dong-Kyu Kim, Hong Ryul Jin, Kyoung Mi Eun, Somasundran Mutusamy, Seong H Cho, Sohee Oh, Dae Woo Ki. Non-Eosinophilic Nasal Polyps Shows Increased Epithelial Proliferation and Localized Disease Pattern in the Early Stage. PloS one. vol 10. issue 10. 2016-06-01. PMID:26439628. |
non-eosinophilic nasal polyps (nps) show less inflammatory changes and are less commonly associated with lower airway inflammatory disorders such as asthma, compared with eosinophilic nps. |
2016-06-01 |
2023-08-13 |
Not clear |
| Yiming Jiang, Ji Xu, Yanqing Chen, Jiali Shi, Chun Zhang, Jiping L. Expression and distribution of epithelial sodium channel in nasal polyp and nasal mucosa. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 272. issue 11. 2016-05-25. PMID:25559464. |
to evaluate the expression and location of epithelial sodium channels (enacs) in human nasal polyp and normal nasal mucosa, and to characterize the relevance of enacs to the development of nps. |
2016-05-25 |
2023-08-13 |
human |
| Mingyu Lee, Dae Woo Kim, Haejin Yoon, Daeho So, Roza Khalmuratova, Chae-Seo Rhee, Jong-Wan Park, Hyun-Woo Shi. Sirtuin 1 attenuates nasal polypogenesis by suppressing epithelial-to-mesenchymal transition. The Journal of allergy and clinical immunology. vol 137. issue 1. 2016-05-23. PMID:26342525. |
nasal polyps (nps) imply a refractory clinical course in patients with chronic rhinosinusitis (crs). |
2016-05-23 |
2023-08-13 |
Not clear |