All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Kazuaki Kawaura, Yukino Ogata, Sokichi Honda, Fumio Soeda, Tetsuya Shirasaki, Kazuo Takaham. Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats. Behavioural brain research. vol 302. 2016-12-13. PMID:26738969. increased the extracellular dopamine level of the nucleus accumbens (nac) in acth-treated rats. 2016-12-13 2023-08-13 rat
Amanda M Barkley-Levenson, Andrey E Ryabinin, John C Crabb. Neuropeptide Y response to alcohol is altered in nucleus accumbens of mice selectively bred for drinking to intoxication. Behavioural brain research. vol 302. 2016-12-13. PMID:26779672. hs mice showed a reduction in npy levels in the nucleus accumbens (nac) - especially in the shell - in ethanol-drinking animals vs. water-drinking controls. 2016-12-13 2023-08-13 mouse
Fawaz Alasmari, P S S Rao, Youssef Sar. Effects of cefazolin and cefoperazone on glutamate transporter 1 isoforms and cystine/glutamate exchanger as well as alcohol drinking behavior in male alcohol-preferring rats. Brain research. vol 1634. 2016-12-13. PMID:26790351. we found that cefazolin and cefoperazone treatments decreased ethanol intake and upregulated both glt-1 isoforms, glt-1a and glt-1b, in nucleus accumbens (nac) and prefrontal cortex (pfc) compared to saline treated group. 2016-12-13 2023-08-13 rat
Sujan C Das, Yusuf S Althobaiti, Fahad S Alshehri, Youssef Sar. Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model. Behavioural brain research. vol 303. 2016-12-13. PMID:26821293. in addition, the expression of glt-1, glast and xct were determined in both medial prefrontal cortex (mpfc) and nucleus accumbens (nac). 2016-12-13 2023-08-13 rat
D-L Jiao, Y Liu, J-D Long, J Du, Y-Y Ju, G-Y Zan, J-G Liu, M Zha. Involvement of dorsal striatal α1-containing GABAA receptors in methamphetamine-associated rewarding memories. Neuroscience. vol 320. 2016-12-13. PMID:26868969. in this study, using the rat-conditioned place preference (cpp) model, a classic animal model for the reward-associated effects of addictive drugs, we found that the expression level of gabaa α1 subunits was significantly decreased in the dorsal striatum (dstr) after conditioned methamphetamine (meth) pairing, and no significant differences were observed in the other four rewarding memory-associated areas (medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala (amy), and dorsal hippocampus (dh)). 2016-12-13 2023-08-13 Not clear
Chi-Ya Kao, Zhisong He, Anthony S Zannas, Oliver Hahn, Claudia Kühne, Judith M Reichel, Elisabeth B Binder, Carsten T Wotjak, Philipp Khaitovich, Christoph W Turc. Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder. Journal of psychiatric research. vol 76. 2016-12-13. PMID:26897419. we compared the transcriptomes of prelimbic cortex, anterior cingulate cortex (acc), basolateral amygdala, central nucleus of amygdala, nucleus accumbens (nac) and ca1 of the dorsal hippocampus between shocked and non-shocked (control) mice, with and without fluoxetine treatment by rna sequencing. 2016-12-13 2023-08-13 mouse
P R Burghardt, D M Krolewski, K E Dykhuis, J Ching, A M Pinawin, S L Britton, L G Koch, S J Watson, H Aki. Nucleus accumbens cocaine-amphetamine regulated transcript mediates food intake during novelty conflict. Physiology & behavior. vol 158. 2016-12-13. PMID:26926827. a 24-h fast differentially affected expression of cocaine-amphetamine regulated transcript (cart) mrna in the nucleus accumbens (nac), where 24-h of fasting reduced cart mrna in lcr rats. 2016-12-13 2023-08-13 rat
Sang Yun Yeom, Choong Hyun Son, Byung Sun Kim, Sung Hyun Tag, Eunjoo Nam, Hyogeun Shin, So Hyun Kim, Haemin Gang, Hyunjoo J Lee, Jungkyu Choi, Heh-In Im, Il-Joo Cho, Nakwon Cho. Multiplexed Detection of Epigenetic Markers Using Quantum Dot (QD)-Encoded Hydrogel Microparticles. Analytical chemistry. vol 88. issue 8. 2016-12-13. PMID:26974493. to demonstrate the potential of our methodology, we present the simultaneous detection of (1) acetylation of lysine 9 of histone 3 (ac-h3k9), (2) dimethylation of h3k9 (2me-h3k9), and (3) trimethylation of h3k9 (3me-h3k9) from three distinct regions in the brain [nucleus accumbens (nac), dorsal striatum (dst), and cerebellum (cbl)] of cocaine-exposed mice. 2016-12-13 2023-08-13 mouse
Bo Pan, Xu-Feng Huang, Chao Den. Aripiprazole and Haloperidol Activate GSK3β-Dependent Signalling Pathway Differentially in Various Brain Regions of Rats. International journal of molecular sciences. vol 17. issue 4. 2016-12-13. PMID:27043526. the present study examined whether aripiprazole differentially affects the gsk3β-dependent signalling pathways in the prefrontal cortex (pfc), nucleus accumbens (nac), and caudate putamen (cpu), in comparison with haloperidol (a d₂r antagonist) and bifeprunox (a d₂r partial agonist). 2016-12-13 2023-08-13 rat
Yao-Ying Ma, Xiusong Wang, Yanhua Huang, Helene Marie, Eric J Nestler, Oliver M Schlüter, Yan Don. Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 18. 2016-12-13. PMID:27091967. specifically, our previous results show that cocaine self-administration generates ampa receptor (ampar)-silent excitatory synapses within the basolateral amygdala (bla) to nucleus accumbens (nac) projection, and maturation of these silent synapses via recruiting calcium-permeable (cp) ampars contributes to incubation of cocaine craving. 2016-12-13 2023-08-13 rat
Reza Arezoomandan, Fariba Khodagholi, Abbas Haghparas. Administration of the Glial Condition Medium in the Nucleus Accumbens Prolong Maintenance and Intensify Reinstatement of Morphine-Seeking Behavior. Neurochemical research. vol 41. issue 4. 2016-11-10. PMID:26547198. the aim of present study was to investigate the direct role of glial cells in nucleus accumbens (nac) in the maintenance and reinstatement of mrp-seeking behavior. 2016-11-10 2023-08-13 Not clear
Elena H Chartoff, Shayla R Ebner, Angela Sparrow, David Potter, Phillip M Baker, Michael E Ragozzino, Mitchell F Roitma. Relative Timing Between Kappa Opioid Receptor Activation and Cocaine Determines the Impact on Reward and Dopamine Release. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26239494. chronic cocaine exposure increases levels of the neuropeptide dynorphin, an endogenous ligand at kappa opioid receptors (kor) that suppresses dopamine release in the nucleus accumbens (nac) and elicits negative affective states upon drug withdrawal. 2016-11-08 2023-08-13 rat
K A Kerstetter, A M Wunsch, K G Nakata, E Donckels, J F Neumaier, Susan M Ferguso. Corticostriatal Afferents Modulate Responsiveness to Psychostimulant Drugs and Drug-Associated Stimuli. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26289144. the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) are both integral components of the corticobasal ganglia-thalamic circuitry that regulates addiction-related behaviors. 2016-11-08 2023-08-13 Not clear
Amir Segev, Irit Akira. Cannabinoids and Glucocorticoids in the Basolateral Amygdala Modulate Hippocampal-Accumbens Plasticity After Stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26289146. growing attention has been focused on nucleus accumbens (nac) plasticity, which regulates mood and motivation. 2016-11-08 2023-08-13 Not clear
Zhi-Qiang Liu, Xun-Hu Gu, Yuan-Jian Yang, Xiao-ping Yin, Li-Jun Xu, Wei Wan. D-Serine in the nucleus accumbens region modulates behavioral sensitization and extinction of conditioned place preference. Pharmacology, biochemistry, and behavior. vol 143. 2016-11-07. PMID:26861675. the aim of the current investigation was to systematically evaluate the role of d-serine on addiction behaviors considered to be mediated by the nucleus accumbens (nac). 2016-11-07 2023-08-13 Not clear
Megan Dunbar Knowles, Patricia Barra de la Tremblaye, Idu Azogu, Hélène Plamondo. Endocannabinoid CB1 receptor activation upon global ischemia adversely impact recovery of reward and stress signaling molecules, neuronal survival and behavioral impulsivity. Progress in neuro-psychopharmacology & biological psychiatry. vol 66. 2016-11-04. PMID:26529486. am251-pretreatment also partially or completely reversed ischemia-induced alterations in th-ir expression at the hippocampus, ventral tegmental area (vta), nucleus accumbens (nac) and basolateral amygdala (bla), normalized drd1-ir at the medial forebrain bundle, and diminished bla and pvn-crh expression. 2016-11-04 2023-08-13 rat
Raj K Nangunoori, Nestor D Tomycz, Michael Y Oh, Donald M Whitin. Deep Brain Stimulation for Obesity: From a Theoretical Framework to Practical Application. Neural plasticity. vol 2016. 2016-11-04. PMID:26819774. in this review, the authors will review some of the work relating to feeding physiology and research surrounding two nodes involved in feeding homeostasis, nucleus accumbens (nac) and hypothalamus, and use this to provide a framework for future investigations of dbs as a viable therapeutic modality for obesity. 2016-11-04 2023-08-13 human
Mohammed Abul Kashem, Selina Ahmed, Nilufa Sultana, Eakhlas U Ahmed, Russell Pickford, Caroline Rae, Omar Šerý, Iain S McGregor, Vladimir J Balca. Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain. Neurochemical research. vol 41. issue 1-2. 2016-11-02. PMID:26801172. extracts from post mortem striatal tissue (dorsal striatum; ds comprising caudate nucleus; cn and putamen; p and ventral striatum; vs constituted by nucleus accumbens; nac) were analysed by high performance liquid chromatography coupled with tandem mass spectrometry. 2016-11-02 2023-08-13 human
Meriem Gaval-Cruz, Richard B Goertz, Daniel J Puttick, Dawn E Bowles, Rebecca C Meyer, Randy A Hall, Daijin Ko, Carlos A Paladini, David Weinshenke. Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. Addiction biology. vol 21. issue 1. 2016-11-01. PMID:25123018. we found a decrease in β-arrestin2 (βarr2) in the nucleus accumbens (nac) following chronic genetic or pharmacological dbh inhibition, and overexpression of βarr2 in the nac normalized cocaine-induced locomotion in dbh knockout (dbh -/-) mice. 2016-11-01 2023-08-13 mouse
Fatemeh Sadeghzadeh, Parastoo Namvar, Farzaneh Sadat Naghavi, Abbas Haghparas. Differential effects of intra-accumbal orexin-1 and -2 receptor antagonists on the expression and extinction of morphine-induced conditioned place preference in rats. Pharmacology, biochemistry, and behavior. vol 142. 2016-10-31. PMID:26704813. orexinergic neurons originate from the hypothalamic nuclei, sending projections toward mesolimbic regions such as the nucleus accumbens (nac). 2016-10-31 2023-08-13 rat