| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Immani Swapna, Brian Bondy, Hitoshi Morikaw. Differential Dopamine Regulation of Ca(2+) Signaling and Its Timing Dependence in the Nucleus Accumbens. Cell reports. vol 15. issue 3. 2017-01-10. PMID:27068462. |
dopamine action in the nucleus accumbens (nac) is thought to drive appetitive behavior and pavlovian reward learning. |
2017-01-10 |
2023-08-13 |
Not clear |
| Weiping Tian, Jiesi Wang, Ke Zhang, Huajing Teng, Chong Li, Moshe Szyf, Zhong Sheng Sun, Mei Zha. Demethylation of c-MYB binding site mediates upregulation of Bdnf IV in cocaine-conditioned place preference. Scientific reports. vol 6. 2017-01-03. PMID:26912258. |
in the present study, using the conditioned place preference (cpp) model, we showed that expression of bdnf iv is upregulated in the nucleus accumbens (nac) of conditioned animals while bdnf i is upregulated in cocaine-treated mice irrespective of conditioning. |
2017-01-03 |
2023-08-13 |
mouse |
| Amy Gancarz, Yan Jouroukhin, Atsushi Saito, Alexey Shevelkin, Lauren E Mueller, Atsushi Kamiya, David M Dietz, Mikhail V Pletniko. DISC1 signaling in cocaine addiction: Towards molecular mechanisms of co-morbidity. Neuroscience research. vol 105. 2016-12-30. PMID:26385055. |
cocaine sa significantly increased expression of disc1 in the nucleus accumbens (nac); while knockdown of disc1 in nac significantly increased cocaine sa and decreased phosphorylation of gsk-3β at ser9 compared to scrambled shrna. |
2016-12-30 |
2023-08-13 |
Not clear |
| Chung-Lung Chan, Daniel S Wheeler, Robert A Wheele. The neural encoding of cocaine-induced devaluation in the ventral pallidum. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26948120. |
cocaine experience affects motivation structures such as the nucleus accumbens (nac) and its major output target, the ventral pallidum (vp). |
2016-12-30 |
2023-08-13 |
rat |
| R Renteria, Z M Jeanes, R A Mangieri, E Y Maier, D M Kircher, T R Buske, R A Morriset. Using In Vitro Electrophysiology to Screen Medications: Accumbal Plasticity as an Engram of Alcohol Dependence. International review of neurobiology. vol 126. 2016-12-27. PMID:27055622. |
the nucleus accumbens (nac) is a central component of the mesocorticolimbic reward system. |
2016-12-27 |
2023-08-13 |
Not clear |
| Marzieh Molaei, Zahra Fatahi, Jalal Zaringhalam, Abbas Haghparas. CB1 Cannabinoid Agonist (WIN55,212-2) Within the Basolateral Amygdala Induced Sensitization to Morphine and Increased the Level of μ-Opioid Receptor and c-fos in the Nucleus Accumbens. Journal of molecular neuroscience : MN. vol 58. issue 4. 2016-12-26. PMID:26803309. |
the basolateral amygdala (bla) is rich of cb1 cannabinoid receptors (cb1r) and has reciprocal connections with the nucleus accumbens (nac) which is involved in opioid sensitization. |
2016-12-26 |
2023-08-13 |
Not clear |
| Takatoshi Hikida, Makiko Morita, Tom Macpherso. Neural mechanisms of the nucleus accumbens circuit in reward and aversive learning. Neuroscience research. vol 108. 2016-12-26. PMID:26827817. |
critical for these processes are the functional role played by two projection neurons within nucleus accumbens (nac); the d1- and d2-expressing neurons. |
2016-12-26 |
2023-08-13 |
Not clear |
| Gislaine Zilli Réus, Maria Augusta Bernardini Dos Santos, Helena Mendes Abelaira, Amanda Luis Maciel, Camila Orlandi Arent, Beatriz Iladi Matias, Lívia Bruchchen, Zuleide Maria Ignácio, Monique Michels, Felipe Dal-Pizzol, André Ferrer Carvalho, Alexandra Ioppi Zugno, João Queved. Antioxidant Therapy Alters Brain MAPK-JNK and BDNF Signaling Path-ways in Experimental Diabetes Mellitus. Current neurovascular research. vol 13. issue 2. 2016-12-26. PMID:26891662. |
following treatment completion, the immunocontent of c-jun n-terminal kinase (jnk), mitogen-activated protein kinase-38 (mapk38), brain-derived neurotrophic factor (bdnf), and protein kinases a and c (pka and pkc) were determined in the prefrontal cortex (pfc), hippocampus, amygdala and nucleus accumbens (nac). |
2016-12-26 |
2023-08-13 |
rat |
| Kristin Feltmann, Ida Fredriksson, Malin Wirf, Björn Schilström, Pia Steenslan. The monoamine stabilizer (-)-OSU6162 counteracts downregulated dopamine output in the nucleus accumbens of long-term drinking Wistar rats. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:26464265. |
we recently established that the monoamine stabilizer (-)-osu6162 (osu6162) decreased voluntary alcohol-mediated behaviors, including alcohol intake and cue/priming-induced reinstatement, in long-term drinking rats, while blunting alcohol-induced dopamine output in the nucleus accumbens (nac) of alcohol-naïve rats. |
2016-12-20 |
2023-08-13 |
rat |
| Sarah J Baracz, Nicholas A Everett, Iain S McGregor, Jennifer L Cornis. Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine-seeking behaviour in rats. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25399704. |
recent findings demonstrated a reduction in meth-induced reward by oxytocin administration into the nucleus accumbens (nac) core. |
2016-12-20 |
2023-08-13 |
rat |
| Bethania Mongi-Bragato, Emiliano Zamponi, Constanza García-Keller, María Amparo Assis, Miriam B Virgolini, Daniel H Mascó, Andreas Zimmer, Liliana M Cancel. Enkephalin is essential for the molecular and behavioral expression of cocaine sensitization. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25431310. |
we found that ko mice do not develop sensitization to the stimulating properties of cocaine on locomotor activity and on dopamine release in the nucleus accumbens (nac). |
2016-12-20 |
2023-08-13 |
mouse |
| Daniel García-Pérez, Cristina Núñez, M Luisa Laorden, M Victoria Milané. Regulation of dopaminergic markers expression in response to acute and chronic morphine and to morphine withdrawal. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25522207. |
using quantitative real-time polymerase chain reaction, immunofluorescence and western blotting, we studied the effects of single morphine administration, morphine dependence and withdrawal on the da markers da transporters (dat), vesicular monoamine transporters (vmat2) and da 2 receptor subtype (drd2), da 1 receptor subtype as well as tyrosine hydroxylase (th) in the ventral tegmental area (vta) and/or nucleus accumbens (nac). |
2016-12-20 |
2023-08-13 |
rat |
| Julia Morud, Louise Adermark, Marta Perez-Alcazar, Mia Ericson, Bo Söderpal. Nicotine produces chronic behavioral sensitization with changes in accumbal neurotransmission and increased sensitivity to re-exposure. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25581387. |
in vitro analysis of synaptic activity in the core and shell of the nucleus accumbens (nac) revealed a decrease in input/output function in both regions of nicotine-treated rats as compared to vehicle-treated control rats. |
2016-12-20 |
2023-08-13 |
rat |
| Ryan G Will, Julia R Martz, Juan M Domingue. The medial preoptic area modulates cocaine-induced locomotion in male rats. Behavioural brain research. vol 305. 2016-12-16. PMID:26947755. |
cocaine-induced locomotion is mediated by dopamine in the nucleus accumbens (nac). |
2016-12-16 |
2023-08-13 |
rat |
| In-Jee You, Sherie R Wright, Alvaro L Garcia-Garcia, Andrew R Tapper, Paul D Gardner, George F Koob, E David Leonardo, Laura M Bohn, Sunmee We. 5-HT1A Autoreceptors in the Dorsal Raphe Nucleus Convey Vulnerability to Compulsive Cocaine Seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 5. 2016-12-14. PMID:26324408. |
in addition, using designer receptors exclusively activated by designer drugs (dreadds) technology, we found that stimulation of the serotonergic dorsal raphe nucleus (drn) afferents to the nucleus accumbens (nac) abolishes cocaine reward and promotes antidepressive-like behaviors. |
2016-12-14 |
2023-08-13 |
mouse |
| Chenxi Cai, Kai Yuan, Junsen Yin, Dan Feng, Yanzhi Bi, Yangding Li, Dahua Yu, Chenwang Jin, Wei Qin, Jie Tia. Striatum morphometry is associated with cognitive control deficits and symptom severity in internet gaming disorder. Brain imaging and behavior. vol 10. issue 1. 2016-12-13. PMID:25720356. |
in addition, caudate volume was correlated with stroop task performance and nucleus accumbens (nac) volume was associated with the internet addiction test (iat) score in the igd group. |
2016-12-13 |
2023-08-13 |
Not clear |
| Petra Suchankova, Jörgen A Engel, Elisabet Jerlha. Sub-chronic Ghrelin Receptor Blockade Attenuates Alcohol- and Amphetamine-Induced Locomotor Stimulation in Mice. Alcohol and alcoholism (Oxford, Oxfordshire). vol 51. issue 2. 2016-12-13. PMID:26330568. |
the findings that ghrelin receptors (ghs-r1a) are expressed in reward-related areas, including the nucleus accumbens (nac) and ventral tegmental area (vta), suggest that ghrelin is a novel reward regulator. |
2016-12-13 |
2023-08-13 |
mouse |
| Laura E Been, Kelsey M Moore, Bruce C Kennedy, Robert L Meise. Metabotropic Glutamate Receptor and Fragile X Signaling in a Female Model of Escalated Aggression. Biological psychiatry. vol 79. issue 8. 2016-12-13. PMID:26342498. |
research in our laboratory demonstrated that repeated aggressive experience in female hamsters resulted in an escalated response to future aggressive encounters and an increase in dendritic spine density on nucleus accumbens (nac) neurons. |
2016-12-13 |
2023-08-13 |
Not clear |
| Bryan F Singer, Bipasha Guptaroy, Curtis J Austin, Isabella Wohl, Vedran Lovic, Jillian L Seiler, Roxanne A Vaughan, Margaret E Gnegy, Terry E Robinson, Brandon J Aragon. Individual variation in incentive salience attribution and accumbens dopamine transporter expression and function. The European journal of neuroscience. vol 43. issue 5. 2016-12-13. PMID:26613374. |
variation in dopamine (da) neurotransmission in the nucleus accumbens (nac) core is thought to contribute to such individual variation. |
2016-12-13 |
2023-08-13 |
rat |
| Luisa Lo Iacono, Alessandro Valzania, Federica Visco-Comandini, Maria Teresa Viscomi, Armando Felsani, Stefano Puglisi-Allegra, Valeria Carol. Regulation of nucleus accumbens transcript levels in mice by early-life social stress and cocaine. Neuropharmacology. vol 103. 2016-12-13. PMID:26706499. |
to this end, we performed genome-wide rna sequencing analysis in the nucleus accumbens (nac), which revealed that 89 transcripts were differentially expressed between s-s and ns-s mice. |
2016-12-13 |
2023-08-13 |
mouse |