| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Swarup Mitra, Craig T Werner, Treefa Shwani, Ana Garcia Lopez, Dale Federico, Kate Higdon, Xiaofang Li, Pedro H Gobira, Shruthi A Thomas, Jennifer A Martin, Chunna An, Ramesh Chandra, Ian Maze, Rachel Neve, Mary Kay Lobo, Amy M Gancarz, David M Diet. A Novel Role for the Histone Demethylase JMJD3 in Mediating Heroin-induced Relapse-Like Behaviors. Biological psychiatry. 2024-07-17. PMID:39019389. |
we examined how histone demethylase jmjd3 in the nucleus accumbens (nac) influences heroin seeking after abstinence from self-administration. |
2024-07-17 |
2024-07-20 |
Not clear |
| Sarah Warren Gooding, Elinor Lewis, Christine Chau, Suhail Sandhu, Julianna Glienke, Jennifer L Whistle. Nucleus accumbens sub-regions experience distinct dopamine release responses following acute and chronic morphine exposure. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005415. |
recent work suggests that distinct vta projections that target the medial and lateral shell of the nucleus accumbens (nac), may play opposing roles in modulating behavior. |
2024-07-15 |
2024-07-18 |
mouse |
| Elizabeth A Eckenwiler, Anna E Ingebretson, Jeffrey J Stolley, Maxine A Fusaro, Alyssa M Romportl, Jack M Ross, Christopher L Petersen, Eera M Kale, Michael S Clark, Selena S Schattauer, Larry S Zweifel, Julia C Lemo. CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005420. |
the nucleus accumbens (nac) mediates reward learning and motivation. |
2024-07-15 |
2024-07-18 |
Not clear |
| Spencer B Huggett, Sharmila Selveraj, John E McGeary, Ami Ikeda, Emerald Yuan, Lauren B Loeffel, Rohan H C Palme. Bulk and Single-cell Transcriptomic Brain Data Identify Overlapping Processes and Cell-types with Human AUD and Mammalian Models of Alcohol Use. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005451. |
this study explores the neurobiological underpinnings of alcohol use disorder (aud) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions associated with addiction (i.e., prefrontal cortex (pfc), nucleus accumbens (nac), and central amygdala (cea)). |
2024-07-15 |
2024-07-18 |
mouse |
| Heather C Aziz, Regina A Mangier. Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice. Biology of sex differences. vol 15. issue 1. 2024-07-13. PMID:39003495. |
the nucleus accumbens (nac), a striatal brain region composed of the core (nacc) and shell (nacsh), has been linked to risk-taking behavior and implicated in reward seeking and evaluation. |
2024-07-13 |
2024-07-16 |
mouse |
| Alexandra Polyzou, Joachim Fuchs, Cristina Kroon, Androniki Kotoula, Foteini Delis, Paul Turko, Katerina Antoniou, Britta Eickholt, George Leondariti. Cell type-specific and subcellular expression of phospholipid phosphatase-related proteins to modulate lyso-phosphatidic acid synaptic signaling in the developing and adult CNS. Journal of neurochemistry. 2024-07-12. PMID:38994820. |
expression patterns of plppr2,4 and 5 were consistent with previous studies, whereas plppr3 and plppr1 exhibited a unique expression profile in nucleus accumbens (nac) and striatum in later developmental and adult stages, which we verified at the protein level for plppr3. |
2024-07-12 |
2024-07-14 |
mouse |
| Randal A Serafini, Zahra Farzinpour, Vishwendra Patel, Abigail M Kelley, Molly Estill, Kerri D Pryce, Farhana Sakloth, Collin D Teague, Angelica Torres-Berrio, Eric J Nestler, Li Shen, Schahram Akbarian, Anushree N Karkhanis, Robert D Blitzer, Venetia Zachario. Nucleus accumbens myocyte enhancer factor 2C mediates the maintenance of peripheral nerve injury-induced physiological and behavioral maladaptations. Pain. 2024-07-10. PMID:38985454. |
preclinical and clinical work has demonstrated altered plasticity and activity in the nucleus accumbens (nac) under chronic pain states, highlighting critical therapeutic avenues for the management of chronic pain conditions. |
2024-07-10 |
2024-07-12 |
mouse |
| Kimberly L P Long, Nerissa E G Hoglen, Alex J Keip, Robert M Klinkel, DéJenaé L See, Joseph Maa, Jenna C Wong, Michael Sherman, Devanand S Manol. Oxytocin receptor function regulates neural signatures of pair bonding and fidelity in the nucleus accumbens. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979148. |
signaling via the oxytocin receptor (oxtr) in the nucleus accumbens (nac) facilitates social reward as well as pair bond formation between mates in socially monogamous prairie voles |
2024-07-09 |
2024-07-12 |
Not clear |
| Gaojie Pan, Bing Zhao, Mutian Zhang, Yanan Guo, Yuhua Yan, Dan Dai, Xiaoxi Zhang, Hui Yang, Jinfei Ni, Zhili Huang, Xia Li, Shumin Dua. Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State. Neuroscience bulletin. 2024-07-09. PMID:38980648. |
the nucleus accumbens (nac) plays an important role in various emotional and motivational behaviors that rely on heightened wakefulness. |
2024-07-09 |
2024-07-12 |
Not clear |
| Angélica Torres-Berrío, Molly Estill, Vishwendra Patel, Aarthi Ramakrishnan, Hope Kronman, Angélica Minier-Toribio, Orna Issler, Caleb J Browne, Eric M Parise, Yentl Y van der Zee, Deena M Walker, Freddyson J Martínez-Rivera, Casey K Lardner, Romain Durand-de Cuttoli, Scott J Russo, Li Shen, Simone Sidoli, Eric J Nestle. Mono-methylation of lysine 27 at histone 3 confers lifelong susceptibility to stress. Neuron. 2024-07-03. PMID:38959894. |
specifically, mice susceptible to early life stress (els) or chronic social defeat stress (csds) displayed increased h3k27me1 enrichment in the nucleus accumbens (nac), a key brain-reward region. |
2024-07-03 |
2024-07-10 |
mouse |
| Danial Farmani, Seyed Mohammadmisagh Moteshakereh, Mohammad Nikoohemmat, Reyhaneh Askari, Sakineh Salehi, Abbas Haghparas. Restraint stress-induced antinociceptive effects in acute pain: Involvement of orexinergic system in the nucleus accumbens. Behavioural brain research. 2024-07-03. PMID:38960330. |
the studies demonstrated that the nucleus accumbens (nac) is critical in modulating pain. |
2024-07-03 |
2024-07-10 |
rat |
| Nur Abdel-Hay, Marina Kabirova, Rami Yak. A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Translational psychiatry. vol 14. issue 1. 2024-07-02. PMID:38956048. |
the pfc interacts with the brain's reward system, including the ventral tegmental area (vta) and nucleus accumbens (nac). |
2024-07-02 |
2024-07-06 |
Not clear |
| Kasey L Brida, Emily T Jorgensen, Robert A Phillips, Catherine E Newman, Jennifer J Tuscher, Emily K Morring, Morgan E Zipperly, Lara Ianov, Kelsey D Montgomery, Madhavi Tippani, Thomas M Hyde, Kristen R Maynard, Keri Martinowich, Jeremy J Da. Reelin marks cocaine-activated striatal ensembles, promotes neuronal excitability, and regulates cocaine reward. bioRxiv : the preprint server for biology. 2024-07-01. PMID:38948801. |
drugs of abuse activate defined neuronal ensembles in brain reward structures such as the nucleus accumbens (nac), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of drug exposure. |
2024-07-01 |
2024-07-03 |
Not clear |
| Natalia F Sardi, Ana C Pescador, Karla E Torres-Chavez, Luana Fische. Revealing a role of brainstem monoaminergic nuclei on the pronociceptive effect of sleep restriction. Neuropharmacology. 2024-07-01. PMID:38950692. |
we have recently demonstrated the involvement of nucleus accumbens (nac) and anterior cingulate cortex (acc) in the pronociceptive effect of sleep restriction. |
2024-07-01 |
2024-07-04 |
rat |
| Liv Engel, Amy R Wolff, Madelyn Blake, Val L Collins, Sonal Sinha, Benjamin T Saunder. Dopamine neurons drive spatiotemporally heterogeneous striatal dopamine signals during learning. Current biology : CB. 2024-06-26. PMID:38925117. |
we used a fluorescent biosensor to monitor dopamine in the nucleus accumbens (nac) core and shell, dorsomedial striatum (dms), and dorsolateral striatum (dls). |
2024-06-26 |
2024-06-29 |
Not clear |
| M Flavia Barbano, Jia Qi, Emma Chen, Uzma Mohammad, Orlando Espinoza, Marcos Candido, Huiling Wang, Bing Liu, Suyun Hahn, François Vautier, Marisela Morale. VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-06-26. PMID:38926603. |
converging evidence indicates that both dopamine and glutamate neurotransmission within the nucleus accumbens (nac) play a role in psychostimulant self-administration and relapse in rodent models. |
2024-06-26 |
2024-06-29 |
mouse |
| V H Azocar, P Petersson, R Fuentes, J A Fuentealb. Differential phase-amplitude coupling in nucleus accumbens and orbitofrontal cortex reflects decision-making during a delay discounting task. Progress in neuro-psychopharmacology & biological psychiatry. 2024-06-25. PMID:38917880. |
the mechanisms underlying impulsive choices are linked to the activity in the nucleus accumbens (nac), the orbitofrontal cortex (ofc), and the dorsolateral striatum (dls). |
2024-06-25 |
2024-06-29 |
Not clear |
| Hui Shen, Zilu Ma, Emma Hans, Ying Duan, Guo-Hua Bi, Yurim C Chae, Alessandro Bonifazi, Francisco O Battiti, Amy Hauck Newman, Zheng-Xiong Xi, Yihong Yan. Neuropharmacology Involvement of dopamine D3 receptor in impulsive choice decision-making in male rats. Neuropharmacology. 2024-06-25. PMID:38917939. |
we found that high-impulsive male rats exhibited lower levels of d2 and d3, and particularly d3, receptor expression in the nucleus accumbens (nac), with no significant changes in the insular, prelimbic, and infralimbic cortices. |
2024-06-25 |
2024-06-29 |
human |
| Bo Zhang, Minmin Guo, Ting Dong, Huajuan Yang, Qiujuan Zhang, Quanxin Yang, Xiaoqian Zhou, Cuiping Mao, Ming Zhan. Disrupted Resting-State Functional Connectivity and Effective Connectivity of the Nucleus Accumbens in Chronic Low Back Pain: A Cross-Sectional Study. Journal of pain research. vol 17. 2024-06-25. PMID:38915479. |
the nucleus accumbens (nac) plays an important role in mediating emotional and cognitive processes and analgesia. |
2024-06-25 |
2024-06-27 |
Not clear |
| Wan Li, Nan Li, Xin Wang, Lei Chen, Mingming Su, Chaohui Zheng, Jiaming Li, Xin Wang, Da Jing, Xuelian Wang, Shunnan G. Microelectrode recording characterization of the nucleus accumbens and the anterior limb of internal capsule in patients with addiction. Neuroscience letters. 2024-06-24. PMID:38914277. |
the nucleus accumbens (nac) and the anterior limb of internal capsule (alic) are effective targets for treating addiction using deep brain stimulation (dbs). |
2024-06-24 |
2024-06-27 |
Not clear |