| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hailei Yu, Boyang Wen, Yun Lu, Bing Xie, Feng Yu, Minglong Zhang, Chunling Ma, Bin Cong, Di Wen, Haitao B. The Role of circTmeff-1 in Morphine Addiction Memory of Mice. Cells. vol 12. issue 15. 2023-08-11. PMID:37566064. |
here, we trained mice on a conditional place preference (cpp) model and collected nucleus accumbens (nac) tissues from day 1 (t0) and day 8 (t1) for high-throughput rna sequencing. |
2023-08-11 |
2023-08-16 |
mouse |
| Yongsheng Zhu, Kejia Wang, Tengfei Ma, Yuanyuan Ji, Yin Lou, Xiaoyu Fu, Ye Lu, Yige Liu, Wei Dang, Qian Zhang, Fangyuan Yin, Kena Wang, Bing Yu, Hongbo Zhang, Jianghua Lai, Yunpeng Wan. Nucleus accumbens D1/D2 circuits control opioid withdrawal symptoms in mice. The Journal of clinical investigation. 2023-08-10. PMID:37561576. |
the nucleus accumbens (nac) is the most promising target for drug use disorder treatment. |
2023-08-10 |
2023-08-16 |
mouse |
| Munir Gunes Kutlu, Jennifer Tat, Brooke A Christensen, Jennifer E Zachry, Erin S Calipar. Dopamine release at the time of a predicted aversive outcome causally controls the trajectory and expression of conditioned behavior. Cell reports. vol 42. issue 8. 2023-08-06. PMID:37543945. |
dopamine release in the nucleus accumbens (nac) is causally linked to adaptive aversive learning, and its dysregulation is a core phenotype in anxiety and stress disorders. |
2023-08-06 |
2023-08-14 |
mouse |
| Haiyan Sun, Zhilin Li, Zhentong Qiu, Yu Shen, Qingchen Guo, Su-Wan Hu, Hai-Lei Ding, Shuming An, Jun-Li Ca. A common neuronal ensemble in nucleus accumbens regulates pain-like behaviour and sleep. Nature communications. vol 14. issue 1. 2023-08-05. PMID:37543693. |
here, we identify a dual-functional ensemble that regulates both pain-like behaviour induced by chronic constrictive injury or complete freund's adjuvant, and sleep wakefulness, in the nucleus accumbens (nac) in mice. |
2023-08-05 |
2023-08-14 |
mouse |
| Yiling Wang, Lirong Tang, Miao Wang, Guowei Wu, Weihua Li, Xuemei Wang, Jiani Wang, Zhenghan Yang, Xiaohong Li, Zhanjiang Li, Qian Chen, Peng Zhang, Zhenchang Wan. The role of functional and structural properties of the nucleus accumbens subregions in eating behavior regulation of bulimia nervosa. The International journal of eating disorders. 2023-08-02. PMID:37530570. |
although studies have demonstrated the involvement of the nucleus accumbens (nac) in the neurobiology of eating disorders, its alterations in bulimia nervosa (bn) remain largely unknown. |
2023-08-02 |
2023-08-14 |
Not clear |
| Giuseppe Tringali, Gianluca Lavanco, Valentina Castelli, Giuseppe Pizzolanti, Martin Kuchar, Diego Currò, Carla Cannizzaro, Anna Brancat. Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking adolescent rats. Focus on calcitonin gene-related peptide's brain levels. Phytotherapy research : PTR. 2023-08-01. PMID:37525534. |
adolescent male rats underwent the intermittent 20% alcohol two-bottle choice paradigm; at the binge day (bd) and the 24 h withdrawal day (wd), we assessed cgrp expression in medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala, hypothalamus and brainstem; in addition, we evaluated sucrose preference, social motivation and drive, nociceptive response, and serum corticosterone levels. |
2023-08-01 |
2023-08-14 |
rat |
| Erika M Vitale, Adrianna Kirckof, Adam S Smit. Partner-seeking and limbic dopamine system are enhanced following social loss in male prairie voles (Microtus ochrogaster). Genes, brain, and behavior. 2023-07-31. PMID:37519035. |
furthermore, we examined dopamine (da) receptor mrna expression in the anterior insula cortex (aic), nucleus accumbens (nac), and anterior cingulate (acc), regions with higher activation in grieving humans. |
2023-07-31 |
2023-08-14 |
Not clear |
| Samah Shahen-Zoabi, Reem Smoum, Alexey Bingor, Etty Grad, Alina Nemirovski, Tawfeeq Shekh-Ahmad, Raphael Mechoulam, Rami Yak. N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice. Translational psychiatry. vol 13. issue 1. 2023-07-31. PMID:37524707. |
we first measured the ecbs and ecb-ls levels in different brain reward system regions following chronic alcohol self-administration using lc-ms. we have found that following chronic intermittent alcohol consumption, n-oleoyl glycine (olgly) levels were significantly elevated in the prefrontal cortex (pfc), and n-oleoyl alanine (olala) was significantly elevated in the pfc, nucleus accumbens (nac) and ventral tegmental area (vta) in a region-specific manner. |
2023-07-31 |
2023-08-14 |
mouse |
| Marion Sourty, Md Taufiq Nasseef, Cédric Champagnol-Di Liberti, Mary Mondino, Vincent Noblet, Eric M Parise, Tamara Markovic, Caleb J Browne, Emmanuel Darcq, Eric J Nestler, Brigitte L Kieffe. Manipulating ΔFOSB in D1-type Medium Spiny Neurons of the nucleus accumbens reshapes whole brain functional connectivity. Biological psychiatry. 2023-07-30. PMID:37517704. |
the transcription factor, Δfosb, acting in the nucleus accumbens (nac), has been shown to control transcriptional and behavioral responses to opioids and other drugs of abuse. |
2023-07-30 |
2023-08-14 |
Not clear |
| Courtney S Wilkinson, Harrison L Blount, Marek Schwendt, Lori A Knacksted. Brain Monoamine Dysfunction in Response to Predator Scent Stress Accompanies Stress-Susceptibility in Female Rats. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509091. |
using a predator scent stress (pss) rodent model of ptsd, we sought to determine if stress-susceptible female rats show altered monoamine concentrations in brain regions associated with ptsd: the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and dorsal (dhipp) and ventral (vhipp) hippocampus. |
2023-07-29 |
2023-08-14 |
rat |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Cody Sargent, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37502884. |
however, vp glut neurons evoked da in reward-associated ventromedial nucleus accumbens (nac), but reduced da in aversion-associated dorsomedial nac. |
2023-07-28 |
2023-08-14 |
human |
| Oyku Dinckol, Jennifer E Zachry, Munir Gunes Kutl. Nucleus accumbens core single cell ensembles bidirectionally respond to experienced versus observed aversive events. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37503203. |
in this study, we recorded single cell activity patterns of nucleus accumbens (nac) core neurons using in vivo optical imaging of calcium transients via miniature scopes. |
2023-07-28 |
2023-08-14 |
Not clear |
| Zhanglei Dong, Saiqiong Xiang, Chi Pan, Chenchen Jiang, Suhao Bao, Wangning Shangguan, Ruifeng Zeng, Jun Li, Qingquan Lian, Binbin W. The excitatory transmission from basolateral nuclues of amygdala to nucleus accumbens shell regulates propofol self-administration through AMPA receptors. Addiction biology. vol 28. issue 8. 2023-07-27. PMID:37500486. |
the glutamatergic transmission from basolateral nucleus of amygdala (bla) to the nucleus accumbens (nac) modulates reward-seeking behaviour; especially, nac shell (nash) is implicated in reward-seeking response. |
2023-07-27 |
2023-08-14 |
rat |
| Michael W Gongwer, Cassandra B Klune, João Couto, Benita Jin, Alexander S Enos, Rita Chen, Drew Friedmann, Laura A DeNard. Brain-wide projections and differential encoding of prefrontal neuronal classes underlying learned and innate threat avoidance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-25. PMID:37491314. |
using tissue clearing and light sheet fluorescence microscopy, we mapped the brain-wide axon collaterals of populations of mpfc neurons that project to nucleus accumbens (nac), ventral tegmental area (vta), or contralateral mpfc (cmpfc). |
2023-07-25 |
2023-08-14 |
mouse |
| Joakim W Ronström, Stephanie B Williams, Andrew Payne, Daniel J Obray, Caylor Hafen, Matthew Burris, K Scott Weber, Scott C Steffensen, Jordan T Yorgaso. Interleukin-10 enhances activity of ventral tegmental area dopamine neurons resulting in increased dopamine release. Brain, behavior, and immunity. 2023-07-15. PMID:37453452. |
dopamine transmission from the ventral tegmental area (vta) to the nucleus accumbens (nac) regulates important aspects of motivation and is influenced by the neuroimmune system. |
2023-07-15 |
2023-08-14 |
Not clear |
| Sriparna Ghosal, Elias Gebara, Eva Ramos-Fernández, Alessandro Chioino, Jocelyn Grosse, Isabelle Guillot de Suduiraut, Olivia Zanoletti, Bernard Schneider, Antonio Zorzano, Simone Astori, Carmen Sand. Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function. Cell reports. vol 42. issue 7. 2023-07-13. PMID:37440411. |
the nucleus accumbens (nac) is a brain hub regulating motivated behaviors, including social competitiveness. |
2023-07-13 |
2023-08-14 |
mouse |
| Juan Enriquez-Traba, Hector E Yarur-Castillo, Rodolfo J Flores, Tenley Weil, Snehashis Roy, Ted B Usdin, Christina T LaGamma, Miguel Arenivar, Huikun Wang, Valerie S Tsai, Amy E Moritz, David R Sibley, Rosario Moratalla, Zachary Z Freyberg, Hugo A Tejed. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. bioRxiv : the preprint server for biology. 2023-07-10. PMID:37425766. |
dopamine release in striatal circuits, including the nucleus accumbens (nac), tracks separable features of reward such as motivation and reinforcement. |
2023-07-10 |
2023-08-14 |
Not clear |
| Julie-Anne Balouek, Christabel A Mclain, Adelaide R Minerva, Rebekah L Rashford, Shannon N Bennett, Forrest D Rogers, Catherine Jensen Peñ. Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-10. PMID:37429717. |
we found that in both male and female mice, els-activated neurons within the nucleus accumbens (nac), and to a lesser-extent the medial prefrontal cortex, were preferentially reactivated by adult stress. |
2023-07-10 |
2023-08-14 |
mouse |
| Daniela Neuhofer, Peter Kaliva. Differential modulation of GABAergic and glutamatergic neurons in the ventral pallidum by GABA and neuropeptides. eNeuro. 2023-07-06. PMID:37414552. |
the ventral pallidum (vp) is an integral locus in the reward circuitry and a major target of gabaergic innervation of both d1-medium spiny neurons (msns) and d2-msns from the nucleus accumbens (nac). |
2023-07-06 |
2023-08-14 |
mouse |
| Astrid M Cardona-Acosta, Omar K Sial, Lyonna F Parise, Tamara Gnecco, Giselle Enriquez Marti, Carlos A Bolaños-Guzmá. Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc pathway. Scientific reports. vol 13. issue 1. 2023-07-05. PMID:37407659. |
in a separate experiment, mice received alp (0, 0.5 mg/kg) and then sacrificed 24-h or 1-month after treatment to assess levels of extracellular signal regulated kinase 1/2 (erk1/2) gene expression, protein phosphorylation, and downstream targets (creb, akt) within the ventral tegmental area (vta) and nucleus accumbens (nac). |
2023-07-05 |
2023-08-14 |
mouse |