All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Fangjie Li, Chengyong Liu, Shan Qin, Xiaoqiu Wang, Qingyun Wan, Zhuoyuan Li, Luyao Wang, Huayuan Yang, Jiehui Jiang, Wenzhong W. The nucleus accumbens functional connectivity in patients with insomnia using resting-state fMRI. Frontiers in neuroscience. vol 17. 2023-08-31. PMID:37650097. the aim of this study was to investigate the functional abnormalities between the nucleus accumbens (nac) and the whole brain in individuals with insomnia disorder (id) using resting-state functional magnetic resonance imaging (fmri). 2023-08-31 2023-09-07 Not clear
Ivette L Gonzalez, Christopher A Turner, Paras R Patel, Noah B Leonardo, Brandon D Luma, Julianna M Richie, Dawen Cai, Cynthia A Chestek, Jill B Becke. Sex Dependent Regional Differences in Dopamine Release Determined by Chronic Fast-Scan Cyclic Voltammetry in Nucleus Accumbens and Dorsal Striatum. bioRxiv : the preprint server for biology. 2023-08-30. PMID:37645814. dopamine (da) signaling in the nucleus accumbens (nac) and dorsolateral striatum (dls) is thought to contribute to sex differences in motivated behaviors. 2023-08-30 2023-09-07 rat
Kyle Duffer, Zachary S Gillis, Sara E Morriso. Excitatory and Inhibitory Signaling in the Nucleus Accumbens Encode Different Aspects of a Pavlovian Cue in Sign Tracking and Goal Tracking Rats. eNeuro. 2023-08-29. PMID:37643864. we have previously shown that cue-evoked excitations in the nucleus accumbens (nac) encode the vigor of both behaviors; in contrast, reward-related responses diverge over the course of training, possibly reflecting neurochemical differences between sign tracker and goal tracker individuals. 2023-08-29 2023-09-07 rat
Ana Verónica Domingues, Ana João Rodrigues, Carina Soares-Cunh. A novel perspective on the role of nucleus accumbens neurons in encoding associative learning. FEBS letters. 2023-08-29. PMID:37643893. the nucleus accumbens (nac) has been considered a key brain region for encoding reward/aversion and cue-outcome associations. 2023-08-29 2023-09-07 Not clear
Jinyu Zhang, Ye Lu, Min Jia, Yuying Bai, Lulu Sun, Ziqing Dong, Wenrong Tian, Fangyuan Yin, Shuguang Wei, Yunpeng Wan. Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice. iScience. vol 26. issue 9. 2023-08-28. PMID:37636073. the number of c-fos positive cells and the expression of kor in the nucleus accumbens (nac), were significantly increased in the prolonged morphine withdrawal mice. 2023-08-28 2023-09-07 mouse
Kenneth D Carr, Sydney P Weiner, Carolina Vasquez, Ann Marie Schmid. Involvement of the Receptor for Advanced Glycation End Products (RAGE) in High Fat-High Sugar Diet-Induced Anhedonia in Rats. Physiology & behavior. 2023-08-25. PMID:37625475. previous results of this laboratory point to impaired nucleus accumbens (nac) insulin signaling as an underpinning of diet-induced anhedonia, based on use of a glucose lick microstructure assay. 2023-08-25 2023-09-07 human
Dengfeng Liu, Zhengyu Xie, Panyang Gu, Xiangyu Li, Yichun Zhang, Xinying Wang, Zhiheng Chen, Suixin Deng, Yousheng Shu, Jia-Da L. Cry1Δ11 mutation induces ADHD-like symptoms through hyperactive dopamine D1 receptor signaling. JCI insight. vol 8. issue 16. 2023-08-22. PMID:37606043. a hyperactive camp signaling pathway was found in the nucleus accumbens (nac) of cry1Δ11 mice. 2023-08-22 2023-09-07 mouse
Michael Okas, Abigail Kastner, Dominic Gioia, John J Woodwar. A brief exposure to toluene vapor alters the intrinsic excitability of D2 medium spiny neurons in the rat ventral striatum. Frontiers in neuroscience. vol 17. 2023-08-21. PMID:37600018. in the present study, we recorded current-evoked spiking of medium spiny neurons (msns) in the nucleus accumbens (nac) core and shell in adolescent rats exposed to an intoxicating concentration of toluene vapor. 2023-08-21 2023-09-07 rat
Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Sophie Holtkamp, Diego Echevarría, István Adorján, Ágota Ádám, András Csilla. Early cellular and synaptic changes in dopaminoceptive forebrain regions of juvenile mice following gestational exposure to valproate. Frontiers in neuroanatomy. vol 17. 2023-08-21. PMID:37603782. we observed a surge of apoptosis on vpa treatment in nearly all investigated subpallial and pallial regions; with a non-significant trend of similar increase the nucleus accumbens (nac) at p7, the age at which the mt pathway reduction has been reported (also supplemented by current findings). 2023-08-21 2023-09-07 mouse
Margaret P Schmill, Zoe Thompson, Daisy Lee, Laurence Haddadin, Shaarang Mitra, Raymond Ezzat, Samantha Shelton, Phillip Levin, Sogol Behnam, Kelly J Huffman, Theodore Garlan. Hippocampal, whole midbrain, red nucleus, and ventral tegmental area volumes are increased by selective breeding for high voluntary wheel-running behavior. Brain, behavior and evolution. 2023-08-21. PMID:37604130. neither linetype nor wheel access affected volumes of the substantia nigra (sn), ventral tegmental area (vta), nucleus accumbens (nac), ventral pallidum (vp) or basolateral amygdala (bla). 2023-08-21 2023-09-07 mouse
Mohammad Akhoondian, Samira Rashtiani, Behrooz Khakpour Taleghani, Mohammad Rostampour, Adele Jafari, Kambiz Rohampou. Lateral habenula deep brain stimulation alleviates depression-like behaviors and reverses the oscillatory pattern in the nucleus accumbens in an animal model of depression. Brain research bulletin. 2023-08-20. PMID:37598800. after surgery and electrode placement in the lateral habenula (lhb), nucleus accumbens (nac), and prelimbic cortex (prl), the cms protocol was applied for 3 weeks to create depression-like models. 2023-08-20 2023-09-07 rat
Veronika Kondev, Mustafa Najeed, Niharika Loomba, Jordan Brown, Danny G Winder, Brad A Grueter, Sachin Pate. Synaptic and cellular endocannabinoid signaling mechanisms regulate stress-induced plasticity of nucleus accumbens somatostatin neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 34. 2023-08-17. PMID:37590414. interneuron populations within the nucleus accumbens (nac) orchestrate excitatory-inhibitory balance, undergo experience-dependent plasticity, and gate-motivated behavior, all biobehavioral processes heavily modulated by endogenous cannabinoid (ecb) signaling. 2023-08-17 2023-09-07 Not clear
Pingping Zhao, Xing Chen, Arash Bellafard, Avaneesh Murugesan, Jonathan Quan, Daniel Aharoni, Peyman Golshan. Accelerated social representational drift in the nucleus accumbens in a model of autism. bioRxiv : the preprint server for biology. 2023-08-14. PMID:37577515. how the nucleus accumbens (nac), as a key hub of reward circuitry, encodes social interaction and whether these representations are altered in asd remain poorly understood. 2023-08-14 2023-08-16 Not clear
Azam Notaj, Amir Erfanparast, Esmaeal Tamaddonfard, Farhad Soltanalinejad-Taghiaba. Exogenous histamine and H 2 receptor activation and H 3 receptor inhibition in nucleus accumbens modulate formalin-induced orofacial nociception through opioid receptors. Behavioural pharmacology. 2023-08-14. PMID:37578392. it has been demonstrated that the nucleus accumbens (nac) plays an important role in modulation of nociception due to its extensive connections with different regions of the brain. 2023-08-14 2023-08-16 rat
Enrica Montalban, Albert Giralt, Lieng Taing, Yuki Nakamura, Assunta Pelosi, Mallory Brown, Benoit de Pins, Emmanuel Valjent, Miquel Martin, Angus C Nairn, Paul Greengard, Marc Flajolet, Denis Hervé, Nicolas Gambardella, Jean-Pierre Roussarie, Jean-Antoine Giraul. Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin. Biological psychiatry. 2023-08-14. PMID:37579933. these effects involve the reward system and dopamine neurons, which modulate neurons in the nucleus accumbens (nac). 2023-08-14 2023-09-07 Not clear
Huanhuan Wang, Yukie Yamahashi, Marcel Riedl, Mutsuki Amano, Kozo Kaibuch. The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569255. we have recently shown that the alzheimer's disease (ad) therapeutic drug donepezil activates the rac1-pak pathway in the nucleus accumbens (nac) for enhanced aversive learning. 2023-08-12 2023-08-16 mouse
Hailei Yu, Boyang Wen, Yun Lu, Bing Xie, Feng Yu, Minglong Zhang, Chunling Ma, Bin Cong, Di Wen, Haitao B. The Role of circTmeff-1 in Morphine Addiction Memory of Mice. Cells. vol 12. issue 15. 2023-08-11. PMID:37566064. here, we trained mice on a conditional place preference (cpp) model and collected nucleus accumbens (nac) tissues from day 1 (t0) and day 8 (t1) for high-throughput rna sequencing. 2023-08-11 2023-08-16 mouse
Yongsheng Zhu, Kejia Wang, Tengfei Ma, Yuanyuan Ji, Yin Lou, Xiaoyu Fu, Ye Lu, Yige Liu, Wei Dang, Qian Zhang, Fangyuan Yin, Kena Wang, Bing Yu, Hongbo Zhang, Jianghua Lai, Yunpeng Wan. Nucleus accumbens D1/D2 circuits control opioid withdrawal symptoms in mice. The Journal of clinical investigation. 2023-08-10. PMID:37561576. the nucleus accumbens (nac) is the most promising target for drug use disorder treatment. 2023-08-10 2023-08-16 mouse
Munir Gunes Kutlu, Jennifer Tat, Brooke A Christensen, Jennifer E Zachry, Erin S Calipar. Dopamine release at the time of a predicted aversive outcome causally controls the trajectory and expression of conditioned behavior. Cell reports. vol 42. issue 8. 2023-08-06. PMID:37543945. dopamine release in the nucleus accumbens (nac) is causally linked to adaptive aversive learning, and its dysregulation is a core phenotype in anxiety and stress disorders. 2023-08-06 2023-08-14 mouse
Haiyan Sun, Zhilin Li, Zhentong Qiu, Yu Shen, Qingchen Guo, Su-Wan Hu, Hai-Lei Ding, Shuming An, Jun-Li Ca. A common neuronal ensemble in nucleus accumbens regulates pain-like behaviour and sleep. Nature communications. vol 14. issue 1. 2023-08-05. PMID:37543693. here, we identify a dual-functional ensemble that regulates both pain-like behaviour induced by chronic constrictive injury or complete freund's adjuvant, and sleep wakefulness, in the nucleus accumbens (nac) in mice. 2023-08-05 2023-08-14 mouse