| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohsen Sharifzadeh, Da-You Zhao, Paul S Bernstein, Werner Gellerman. Resonance Raman imaging of macular pigment distributions in the human retina. Journal of the Optical Society of America. A, Optics, image science, and vision. vol 25. issue 4. 2008-06-19. PMID:18382494. |
we demonstrate that rri is capable of quantifying and imaging the spatially strongly varying mp distribution in the human retina. |
2008-06-19 |
2023-08-12 |
human |
| Mohsen Sharifzadeh, Da-You Zhao, Paul S Bernstein, Werner Gellerman. Resonance Raman imaging of macular pigment distributions in the human retina. Journal of the Optical Society of America. A, Optics, image science, and vision. vol 25. issue 4. 2008-06-19. PMID:18382494. |
using laser excitation of the mp molecules at 488nm, and sequential camera detection of light emitted back from the retina at the mp's strongest raman peak position and at an off-peak position, rri maps of mp are obtained at a resolution below 50microm within a fraction of a second per exposure. |
2008-06-19 |
2023-08-12 |
human |
| John M Nolan, James M Stringham, Stephen Beatty, D Max Snodderl. Spatial profile of macular pigment and its relationship to foveal architecture. Investigative ophthalmology & visual science. vol 49. issue 5. 2008-06-09. PMID:18436846. |
macular pigment (mp) is composed of two dietary carotenoids, lutein and zeaxanthin, and a carotenoid generated by the retina, meso-zeaxanthin. |
2008-06-09 |
2023-08-12 |
Not clear |
| Richard A Bone, Betty Brener, Jorge C Giber. Macular pigment, photopigments, and melanin: distributions in young subjects determined by four-wavelength reflectometry. Vision research. vol 47. issue 26. 2008-03-19. PMID:17937965. |
we have developed an objective procedure, using a modified retinal camera, to determine macular pigment (mp) optical density distributions in the human retina. |
2008-03-19 |
2023-08-12 |
human |
| James M Stringham, Billy R Hammon. Compensation for light loss due to filtering by macular pigment: relation to hue cancellation. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists). vol 27. issue 3. 2007-08-13. PMID:17470235. |
such compensation must be required in order to maintain colour constancy across the retina where mp levels are changing quickly and dramatically. |
2007-08-13 |
2023-08-12 |
Not clear |
| Meike Trieschmann, Stephen Beatty, John M Nolan, Hans Werner Hense, Britta Heimes, Ulrike Austermann, Manfred Fobker, Daniel Pauleikhof. Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: the LUNA study. Experimental eye research. vol 84. issue 4. 2007-05-18. PMID:17306793. |
macular pigment (mp), consisting of lutein (l) and zeaxanthin (z), is believed to protect the retina from photo-oxidative damage. |
2007-05-18 |
2023-08-12 |
human |
| James M Stringham, Billy R Hammond, Billy R Wooten, D Max Snodderl. Compensation for light loss resulting from filtering by macular pigment: relation to the S-cone pathway. Optometry and vision science : official publication of the American Academy of Optometry. vol 83. issue 12. 2007-01-18. PMID:17164681. |
as a result of the uneven topographic distribution of mp, spatial nonuniformities in visual perception would result if the visual system did not compensate for filtering differences across the central retina. |
2007-01-18 |
2023-08-12 |
Not clear |
| Mohsen Sharifzadeh, Paul S Bernstein, Werner Gellerman. Nonmydriatic fluorescence-based quantitative imaging of human macular pigment distributions. Journal of the Optical Society of America. A, Optics, image science, and vision. vol 23. issue 10. 2006-12-21. PMID:16985523. |
projecting a large diameter, 488 nm excitation spot onto the retina, centered on the fovea, but extending into the macular periphery, and comparing lipofuscin fluorescence intensities outside and inside the foveal area, it is possible to spatially map out the distribution of mp. |
2006-12-21 |
2023-08-12 |
human |
| S H Melissa Liew, Clare E Gilbert, Tim D Spector, John Mellerio, Frederik J Van Kuijk, Stephen Beatty, Fred Fitzke, John Marshall, Christopher J Hammon. Central retinal thickness is positively correlated with macular pigment optical density. Experimental eye research. vol 82. issue 5. 2006-07-05. PMID:16380117. |
macular pigment (mp) has been suggested to have a protective role in age-related macular degeneration by reducing the amount of oxidative stress on the retina. |
2006-07-05 |
2023-08-12 |
human |
| S H Melissa Liew, Clare E Gilbert, Tim D Spector, John Mellerio, Frederik J Van Kuijk, Stephen Beatty, Fred Fitzke, John Marshall, Christopher J Hammon. Central retinal thickness is positively correlated with macular pigment optical density. Experimental eye research. vol 82. issue 5. 2006-07-05. PMID:16380117. |
mp levels peak at the foveal center, where it is found predominantly in the receptor axon and inner plexiform layers of the retina. |
2006-07-05 |
2023-08-12 |
human |
| K Neelam, N O'Gorman, J Nolan, O O'Donovan, K G Au Eong, S Beatt. Macular pigment levels following successful macular hole surgery. The British journal of ophthalmology. vol 89. issue 9. 2005-10-11. PMID:16113359. |
macular pigment (mp) is composed of two hydroxycarotenoids contained within the photoreceptors and the axons of the central neurosensory retina, with peak concentrations in the henle layer. |
2005-10-11 |
2023-08-12 |
Not clear |
| Joanne D Burke, Joanne Curran-Celentano, Adam J Wenze. Diet and serum carotenoid concentrations affect macular pigment optical density in adults 45 years and older. The Journal of nutrition. vol 135. issue 5. 2005-07-06. PMID:15867305. |
protection of the central retina by mp is suggested, but data are limited. |
2005-07-06 |
2023-08-12 |
human |
| Billy R Hammond, Billy R Wooten, Bill Smollo. Assessment of the validity of in vivo methods of measuring human macular pigment optical density. Optometry and vision science : official publication of the American Academy of Optometry. vol 82. issue 5. 2005-05-24. PMID:15894915. |
as a result of the putative protective role of lutein and zeaxanthin at the site of the retina (macular pigment [mp]), interest in the noninvasive measurement of these retinal carotenoids is increasing. |
2005-05-24 |
2023-08-12 |
human |
| Dao-Yi Yu, Stephen J Cringle, Erning Su, Paula K Yu, Mark S Humayun, Giorgio Dori. Laser-induced changes in intraretinal oxygen distribution in pigmented rabbits. Investigative ophthalmology & visual science. vol 46. issue 3. 2005-04-13. PMID:15728557. |
to make the first measurements of intraretinal oxygen distribution and consumption after laser photocoagulation of the retina and to compare the efficiency of micropulsed (mp) and continuous wave (cw) laser delivery in achieving an oxygen benefit in the treated area. |
2005-04-13 |
2023-08-12 |
Not clear |
| Stephen Beatty, John Nolan, Heather Kavanagh, Orla O'Donova. Macular pigment optical density and its relationship with serum and dietary levels of lutein and zeaxanthin. Archives of biochemistry and biophysics. vol 430. issue 1. 2004-09-23. PMID:15325913. |
it has been shown that mp is entirely of dietary origin, and that l and z levels in serum, diet, and retina correlate. |
2004-09-23 |
2023-08-12 |
Not clear |
| Igor Ermakov, Maia Ermakova, Werner Gellermann, Paul S Bernstei. Macular pigment Raman detector for clinical applications. Journal of biomedical optics. vol 9. issue 1. 2004-04-06. PMID:14715066. |
we introduce a novel noninvasive optical instrument, an mp raman detector, for assessment of the carotenoid status of the human retina in vivo. |
2004-04-06 |
2023-08-12 |
human |
| M Trieschmann, G Spital, A Lommatzsch, E van Kuijk, F Fitzke, A C Bird, D Pauleikhof. Macular pigment: quantitative analysis on autofluorescence images. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. vol 241. issue 12. 2004-02-26. PMID:14618343. |
macular pigment (mp) reduces oxidative damage in the central retina and can be quantified by flicker-photometric analysis (hfp) of mp optical density. |
2004-02-26 |
2023-08-12 |
Not clear |
| Yin Chang, Feng-Lih Lee, Shih-Jen Chen, Sheng-Fu Che. Optical measurement of human retinal macular pigment and its spatial distribution with age. Medical physics. vol 29. issue 11. 2003-06-16. PMID:12462729. |
however, the cause of the mp extension in the retina with age is unknown. |
2003-06-16 |
2023-08-12 |
human |
| Billy R Wooten, Billy R Hammon. Macular pigment: influences on visual acuity and visibility. Progress in retinal and eye research. vol 21. issue 2. 2002-11-13. PMID:12062535. |
there is increasing evidence that the macular pigment (mp) carotenoids lutein (l) and zeaxanthin (z) protect the retina and lens from age-related loss. |
2002-11-13 |
2023-08-12 |
human |
| Wendy M R Broekmans, Tos T J M Berendschot, Ineke A A Klöpping-Ketelaars, Arjan J de Vries, R Alexandra Goldbohm, Lilian B M Tijburg, Alwine F M Kardinaal, Geert van Poppe. Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin. The American journal of clinical nutrition. vol 76. issue 3. 2002-09-16. PMID:12198005. |
macular pigment (mp), concentrated in the central area of the retina, contains the carotenoids lutein and zeaxanthin. |
2002-09-16 |
2023-08-12 |
Not clear |