| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Achiron, G Lavie, I Kishner, Y Stern, I Sarova-Pinhas, T Ben-Aharon, Y Barak, H Raz, M Lavie, T Barliya, M Faibel, I R Cohen, M Mande. T cell vaccination in multiple sclerosis relapsing-remitting nonresponders patients. Clinical immunology (Orlando, Fla.). vol 113. issue 2. 2004-11-19. PMID:15451472. |
twenty nonresponders relapsing-remitting ms patients were immunized with autologous attenuated t cell lines after activation with synthetic myelin basic protein (mbp) and myelin oligodendrocyte glycoprotein (mog) encephalitogenic peptides. |
2004-11-19 |
2023-08-12 |
Not clear |
| Eric Birgbauer, Tadimeti S Rao, Michael Web. Lysolecithin induces demyelination in vitro in a cerebellar slice culture system. Journal of neuroscience research. vol 78. issue 2. 2004-11-15. PMID:15378614. |
this demyelination was observed by immunostaining for the myelin components myelin basic protein (mbp), myelin oligodendrocyte glycoprotein (mog), and 2', 3'-cyclic nucleotide 3'-phosphodiesterase (cnpase). |
2004-11-15 |
2023-08-12 |
human |
| Eric Birgbauer, Tadimeti S Rao, Michael Web. Lysolecithin induces demyelination in vitro in a cerebellar slice culture system. Journal of neuroscience research. vol 78. issue 2. 2004-11-15. PMID:15378614. |
after a transient demyelinating insult with lysolecithin in vitro, the cultures recovered with oligodendrocyte differentiation recapitulating a normal time course; there was initially re-expression of cnpase and mbp during this recovery, and this was followed by mog. |
2004-11-15 |
2023-08-12 |
human |
| Maria Ngu-Schwemlein, Michele Corzett, Kevin H Thornton, Rod Balhorn, Monique Cosma. Extracellular domain of myelin oligodendrocyte glycoprotein (MOG) exhibits solvent-dependent conformational transitions. Protein and peptide letters. vol 10. issue 5. 2004-11-09. PMID:14561137. |
extracellular domain of myelin oligodendrocyte glycoprotein (mog) exhibits solvent-dependent conformational transitions. |
2004-11-09 |
2023-08-12 |
rat |
| Estelle Bettelli, Brandon Sullivan, Susanne J Szabo, Raymond A Sobel, Laurie H Glimcher, Vijay K Kuchro. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of experimental medicine. vol 200. issue 1. 2004-10-26. PMID:15238607. |
t-bet-deficient mice immunized with myelin oligodendrocyte glycoprotein (mog) were resistant to the development of eae. |
2004-10-26 |
2023-08-12 |
mouse |
| Hiroshi Sakuma, Kuniko Kohyama, Il-Kwon Park, Akira Miyakoshi, Naoyuki Tanuma, Yoh Matsumot. Clinicopathological study of a myelin oligodendrocyte glycoprotein-induced demyelinating disease in LEW.1AV1 rats. Brain : a journal of neurology. vol 127. issue Pt 10. 2004-10-15. PMID:15282218. |
here, we have successfully induced various subtypes of experimental autoimmune encephalitis (eae) in lew.1av1 rats carrying rt1(av1) on the lewis background genes by immunization with recombinant rat myelin oligodendrocyte glycoprotein (mog) in various solutions with adjuvants. |
2004-10-15 |
2023-08-12 |
rat |
| Paula Mañá, Melinda Goodyear, Claude Bernard, Ryo Tomioka, Manuel Freire-Garabal, David Liñare. Tolerance induction by molecular mimicry: prevention and suppression of experimental autoimmune encephalomyelitis with the milk protein butyrophilin. International immunology. vol 16. issue 3. 2004-09-28. PMID:14978022. |
in this study, we investigate the molecular mimicry between the extracellular ig-like domain of the cow's milk protein butyrophilin (btn) and the extracellular domain of myelin oligodendrocyte glycoprotein (mog), a candidate autoantigen in ms. interestingly, we found that as a result of a non-pathogenic cross-reactivity that is localized to a subdominant region of mog, treatment of c57bl/6 mice with btn either before or after immunization with mog was shown to prevent and also suppress the clinical manifestations of eae. |
2004-09-28 |
2023-08-12 |
mouse |
| Roberto Furlan, AslI Kurne, Alessandra Bergami, Elena Brambilla, Raffaella Maucci, Laura Gasparini, Erica Butti, Giancarlo Comi, Ennio Ongini, Gianvito Martin. A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 150. issue 1-2. 2004-09-14. PMID:15081244. |
preventive treatment of experimental autoimmune encephalomyelitis (eae)-induced in c57bl/6 mice by immunization with myelin oligodendrocyte glycoprotein (mog) peptide 35-55-with the no-releasing derivative of flurbiprofen hct1026 delayed disease onset and significantly decreased disease severity. |
2004-09-14 |
2023-08-12 |
mouse |
| Tracey L Papenfuss, Connie J Rogers, Ingrid Gienapp, Maria Yurrita, Melanie McClain, Nicole Damico, Janie Valo, Fei Song, Caroline C Whitacr. Sex differences in experimental autoimmune encephalomyelitis in multiple murine strains. Journal of neuroimmunology. vol 150. issue 1-2. 2004-09-14. PMID:15081249. |
greater severity of eae was observed in the female sjl immunized with two different peptides of myelin proteolipid protein (plp) and myelin oligodendrocyte glycoprotein (mog) as well as in the female asw relative to males. |
2004-09-14 |
2023-08-12 |
mouse |
| Michael J Haas, Amjad Mreyoud, Miriam Fishman, Arshag D Mooradia. Microarray analysis of thyroid hormone-induced changes in mRNA expression in the adult rat brain. Neuroscience letters. vol 365. issue 1. 2004-09-14. PMID:15234464. |
the expression of the phosphodiesterase enpp2, myelin oligodendrocyte glycoprotein (mog), microtubule-associated protein 2 (map2), growth hormone (gh), ca(2+)/calmodulin-dependent protein kinase beta-subunit (camk2b), neuron-specific protein pep-19 (pcp4), a sodium-dependent neurotransmitter, and the myelin-associated glycoprotein (s-mag) was significantly increased. |
2004-09-14 |
2023-08-12 |
rat |
| Emily Mathey, Constanze Breithaupt, Anna S Schubart, Christopher Liningto. Commentary: Sorting the wheat from the chaff: identifying demyelinating components of the myelin oligodendrocyte glycoprotein (MOG)-specific autoantibody repertoire. European journal of immunology. vol 34. issue 8. 2004-09-14. PMID:15259003. |
commentary: sorting the wheat from the chaff: identifying demyelinating components of the myelin oligodendrocyte glycoprotein (mog)-specific autoantibody repertoire. |
2004-09-14 |
2023-08-12 |
human |
| Emily Mathey, Constanze Breithaupt, Anna S Schubart, Christopher Liningto. Commentary: Sorting the wheat from the chaff: identifying demyelinating components of the myelin oligodendrocyte glycoprotein (MOG)-specific autoantibody repertoire. European journal of immunology. vol 34. issue 8. 2004-09-14. PMID:15259003. |
myelin oligodendrocyte glycoprotein (mog) is the only myelin protein known to initiate a demyelinating autoantibody response in eae, an animal model for multiple sclerosis (ms). |
2004-09-14 |
2023-08-12 |
human |
| Hans-Christian von Büdingen, Stephen L Hauser, Jean-Christophe Ouallet, Naoyuki Tanuma, Til Menge, Claude P Genai. Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. European journal of immunology. vol 34. issue 8. 2004-09-14. PMID:15259004. |
preliminary observations of humoral immunity against the myelin oligodendrocyte glycoprotein (mog) in experimental allergic encephalomyelitis (eae) and human multiple sclerosis (ms) suggest that a subset of anti-mog autoantibodies directed against conformational epitopes is of pathogenic predominance. |
2004-09-14 |
2023-08-12 |
human |
| Naoto Kawakami, Silke Lassmann, Zhaoxia Li, Francesca Odoardi, Thomas Ritter, Tjalf Ziemssen, Wolfgang E F Klinkert, Joachim W Ellwart, Monika Bradl, Kimberly Krivacic, Hans Lassmann, Richard M Ransohoff, Hans-Dieter Volk, Hartmut Wekerle, Christopher Linington, Alexander Flüge. The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. The Journal of experimental medicine. vol 199. issue 2. 2004-09-03. PMID:14734524. |
potentially lethal eae is mediated by myelin basic protein (mbp)-specific t cells in lewis rats, whereas transfer of s100beta- or myelin oligodendrocyte glycoprotein (mog)-specific t cells causes intense inflammatory response in the central nervous system (cns) with minimal disease. |
2004-09-03 |
2023-08-12 |
rat |
| Eilhard Mix, Saleh Ibrahim, Jens Pahnke, Dirk Koczan, Christian Sina, Tobias Böttcher, Hans-Jürgen Thiesen, Arndt Rolf. Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process. Journal of neuroimmunology. vol 151. issue 1-2. 2004-08-18. PMID:15145614. |
experimental autoimmune encephalomyelitis (eae) induced by myelin oligodendrocyte glycoprotein (mog) is a well-established animal model of multiple sclerosis (ms) in rodents. |
2004-08-18 |
2023-08-12 |
mouse |
| Marcel Zocher, Patrick A Baeuerl. A bispecific single-chain antibody fusion protein for targeted depletion of autoreactive B cells via unstimulated human T lymphocytes. Molecular immunology. vol 41. issue 5. 2004-08-17. PMID:15183929. |
we describe the design, purification and characterization of mogxanti-cd3, a single-chain bispecific antibody fusion protein recognizing b cell receptors specific for the human myelin oligodendrocyte glycoprotein (mog) and to cd3 on human t cells. |
2004-08-17 |
2023-08-12 |
human |
| Kamruz Darabi, Alexey Y Karulin, Bernhard O Boehm, Harald H Hofstetter, Zsuzsa Fabry, Joseph C LaManna, Juan C Chavez, Magdalena Tary-Lehmann, Paul V Lehman. The third signal in T cell-mediated autoimmune disease? Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 1. 2004-08-17. PMID:15210763. |
this situation is reflected after the immunization of c57bl/6 mice with the neuroantigen myelin oligodendrocyte glycoprotein (mog) with cfa, which primes a type 1 t cell response but does not lead to clinical or histological manifestation of experimental allergic encephalomyelitis unless pertussis toxin is injected in addition. |
2004-08-17 |
2023-08-12 |
mouse |
| Felix Bischof, Adriaan Bins, Michael Dürr, Yinka Zevering, Arthur Melms, Ada M Kruisbee. A structurally available encephalitogenic epitope of myelin oligodendrocyte glycoprotein specifically induces a diversified pathogenic autoimmune response. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 1. 2004-08-17. PMID:15210822. |
multiple sclerosis is an inflammatory disease of the cns that involves immune reactivity against myelin oligodendrocyte glycoprotein (mog), a type i transmembrane protein located at the outer surface of cns myelin. |
2004-08-17 |
2023-08-12 |
mouse |
| David Liñares, Paula Mañá, Melinda Goodyear, Anne M Chow, Chelsea Clavarino, Nicholas D Huntington, Louise Barnett, Frank Koentgen, Ryo Tomioka, Claude C A Bernard, Manuel Freire-Garabal, Hugh H Rei. The magnitude and encephalogenic potential of autoimmune response to MOG is enhanced in MOG deficient mice. Journal of autoimmunity. vol 21. issue 4. 2004-08-10. PMID:14624757. |
myelin oligodendrocyte glycoprotein (mog) is a minor component of central nervous system myelin presumably implicated in the pathogenesis of multiple sclerosis (ms). |
2004-08-10 |
2023-08-12 |
mouse |
| Joan M Boggs, Huimin Wan. Co-clustering of galactosylceramide and membrane proteins in oligodendrocyte membranes on interaction with polyvalent carbohydrate and prevention by an intact cytoskeleton. Journal of neuroscience research. vol 76. issue 3. 2004-07-29. PMID:15079863. |
myelin oligodendrocyte glycoprotein (mog), proteolipid protein (plp), mapk, and some phosphotyrosine-containing proteins were found to co-cluster with galc and mbp, but myelin-associated glycoprotein (mag) and phosphatidylinositol-4,5-bisphosphate (pip(2)) did not. |
2004-07-29 |
2023-08-12 |
cattle |