| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reinout Raijmakers, Judith Vogelzangs, Jos Raats, Maret Panzenbeck, Maureen Corby, Huiping Jiang, Michael Thibodeau, Nancy Haynes, Walther J van Venrooij, Ger J M Pruijn, Brian Wernebur. Experimental autoimmune encephalomyelitis induction in peptidylarginine deiminase 2 knockout mice. The Journal of comparative neurology. vol 498. issue 2. 2007-01-16. PMID:16856138. |
to study the role of cns protein citrullination in eae development, we induced eae with a peptide derived from myelin oligodendrocyte glycoprotein (mog(35-55)) in mice lacking the peptidylarginine deiminase 2 (pad2) protein, because this enzyme was the most likely candidate to be involved in catalyzing cns protein citrullination in the diseased state. |
2007-01-16 |
2023-08-12 |
mouse |
| Nicholas D Huntington, Ryo Tomioka, Chelsea Clavarino, Anne M Chow, David Liñares, Paula Maña, Jamie Rossjohn, Teresa G Cachero, Fang Qian, Susan L Kalled, Claude C A Bernard, Hugh H Rei. A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses. International immunology. vol 18. issue 10. 2007-01-16. PMID:16914508. |
using a b and t cell-mediated mouse model of multiple sclerosis (ms), myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), we observed that a baff/april antagonist (soluble bcma-fc) inhibited central nervous system inflammation and demyelination such that it suppressed the onset and progression of clinical symptoms of eae. |
2007-01-16 |
2023-08-12 |
mouse |
| Maria K Storch, Jan Bauer, Christopher Linington, Tomas Olsson, Robert Weissert, Hans Lassman. Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related. Journal of neuropathology and experimental neurology. vol 65. issue 12. 2007-01-16. PMID:17146287. |
in this study, we analyzed a large spectrum of different rat strains actively immunized with myelin oligodendrocyte glycoprotein (mog), a model strongly mimicking ms for cortical demyelination. |
2007-01-16 |
2023-08-12 |
rat |
| Peter Bannerman, Ashleigh Hahn, Athena Soulika, Vittorio Gallo, David Pleasur. Astrogliosis in EAE spinal cord: derivation from radial glia, and relationships to oligodendroglia. Glia. vol 55. issue 1. 2007-01-05. PMID:17009237. |
we now report that coincident with the first appearance of inflammation and clinical deficits in mice with myelin oligodendrocyte glycoprotein peptide (mog peptide)-induced eae, the radially oriented, bipolar, gfap, and blbp positive cells (adult radial glia) present in normal spinal cord white matter undergo mitosis and phenotypic transformation to hypertrophic astroglia. |
2007-01-05 |
2023-08-12 |
mouse |
| Karen M Spach, Faye E Nashold, Bonnie N Dittel, Colleen E Haye. IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 9. 2006-12-13. PMID:17056528. |
we report that vitamin d(3) and 1,25-(oh)(2)d(3) strongly inhibited myelin oligodendrocyte peptide (mog(35-55))-induced eae in c57bl/6 mice, but completely failed to inhibit eae in mice with a disrupted il-10 or il-10r gene. |
2006-12-13 |
2023-08-12 |
mouse |
| Yun-Feng Fu, Yi-Na Zhu, Jia Ni, Xiang-Gen Zhong, Wei Tang, Yu-Dan Re, Li-Ping Shi, Jin Wan, Yi-Fu Yang, Chong Yuan, Fa-Jun Nan, Brian R Lawson, Jian-Ping Zu. A reversible S-adenosyl-L-homocysteine hydrolase inhibitor ameliorates experimental autoimmune encephalomyelitis by inhibiting T cell activation. The Journal of pharmacology and experimental therapeutics. vol 319. issue 2. 2006-12-04. PMID:16914558. |
in this study, we examined the effects of dz2002 on active eae induced by myelin oligodendrocyte glycoprotein (mog) 35-55 in female c57bl/6 mice. |
2006-12-04 |
2023-08-12 |
mouse |
| Dimitrios Papadopoulos, Lisa Ewans, Danielle Pham-Dinh, Johanna Knott, Richard Reynold. Upregulation of alpha-synuclein in neurons and glia in inflammatory demyelinating disease. Molecular and cellular neurosciences. vol 31. issue 4. 2006-11-22. PMID:16503161. |
alpha-synuclein expression was examined in the spinal cord of myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) in rats using immunofluorescence and in situ hybridization and in postmortem tissues from cases of secondary progressive ms using immunohistochemistry. |
2006-11-22 |
2023-08-12 |
rat |
| Muriel B Sättler, Iris Demmer, Sarah K Williams, Katharina Maier, Doron Merkler, Ivana Gadjanski, Christine Stadelmann, Mathias Bähr, Ricarda Die. Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764858. |
we have characterized previously time course and mechanisms of neuronal apoptosis in a rat model of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2006-11-14 |
2023-08-12 |
rat |
| Yangtai Guan, Kenneth S Shindler, Philomela Tabuena, A M Rostam. Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice. Journal of neuroimmunology. vol 178. issue 1-2. 2006-11-14. PMID:16828169. |
recently, myelin oligodendrocyte glycoprotein (mog)-specific tcr transgenic mice were found to develop spontaneous isolated optic neuritis in the absence of eae. |
2006-11-14 |
2023-08-12 |
mouse |
| Cécile Delarasse, Bruno Della Gaspera, Chuan Wei Lu, François Lachapelle, Antoinette Gelot, Diana Rodriguez, André Dautigny, Claude Genain, Danielle Pham-Din. Complex alternative splicing of the myelin oligodendrocyte glycoprotein gene is unique to human and non-human primates. Journal of neurochemistry. vol 98. issue 6. 2006-11-07. PMID:16903876. |
we performed transcriptomic analyses for a gene expressed only in mammalian cns, myelin oligodendrocyte glycoprotein (mog). |
2006-11-07 |
2023-08-12 |
mouse |
| A Pahuja, R A Maki, P A Hevezi, A Chen, G M Verge, S M Lechner, R B Roth, A Zlotnik, D G Allev. Experimental autoimmune encephalomyelitis develops in CC chemokine receptor 7-deficient mice with altered T-cell responses. Scandinavian journal of immunology. vol 64. issue 4. 2006-10-31. PMID:16970675. |
to address whether ccr7 plays a role in the development of autoimmunity, we induced experimental autoimmune encephalomyelitis in ccr7-deficient mice on a c57bl/6 background (ccr7(-/-)) using the neuroantigen, myelin oligodendrocyte glycoprotein 35-55 amino acid peptide (mog((35-55))) and bordetella pertussis toxin (ptx). |
2006-10-31 |
2023-08-12 |
mouse |
| Gurumoorthy Krishnamoorthy, Hans Lassmann, Hartmut Wekerle, Andreas Hol. Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation. The Journal of clinical investigation. vol 116. issue 9. 2006-10-30. PMID:16955140. |
ose mice have recombination-competent immune cells expressing a tcr-alphabeta specific for myelin oligodendrocyte glycoprotein (mog) aa 35-55 peptide in the context of i-ab along with an ig j region replaced by the recombined heavy chain of a monoclonal antibody binding to a conformational epitope on mog. |
2006-10-30 |
2023-08-12 |
mouse |
| Yi-Na Zhu, Xiang-Gen Zhong, Jia-Quan Feng, Yi-Fu Yang, Yun-Feng Fu, Jia Ni, Qun-Fang Liu, Wei Tang, Wei-Min Zhao, Jian-Ping Zu. Periplocoside E inhibits experimental allergic encephalomyelitis by suppressing interleukin 12-dependent CCR5 expression and interferon-gamma-dependent CXCR3 expression in T lymphocytes. The Journal of pharmacology and experimental therapeutics. vol 318. issue 3. 2006-10-10. PMID:16751252. |
c57bl/6 mice immunized with myelin oligodendrocyte glyco-protein (mog) were treated with pse following immunization and continued throughout the study. |
2006-10-10 |
2023-08-12 |
mouse |
| Doron Merkler, Tristan Ernsting, Martin Kerschensteiner, Wolfgang Brück, Christine Stadelman. A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination. Brain : a journal of neurology. vol 129. issue Pt 8. 2006-09-29. PMID:16714315. |
lesions were stereotactically targeted to the cerebral cortex by injection of pro-inflammatory mediators in animals that were immunized subclinically with myelin oligodendrocyte glycoprotein (mog). |
2006-09-29 |
2023-08-12 |
rat |
| Katsuichi Miyamoto, Sachiko Miyake, Miho Mizuno, Nobuyuki Oka, Susumu Kusunoki, Takashi Yamamur. Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway. Brain : a journal of neurology. vol 129. issue Pt 8. 2006-09-29. PMID:16835249. |
celecoxib, but not other cox-2 inhibitors such as nimesulid, prevented myelin oligodendrocyte glycoprotein (mog) induced eae when administrated orally on the day of disease induction. |
2006-09-29 |
2023-08-12 |
mouse |
| Doron Merkler, Robert Böscke, Barthel Schmelting, Boldizsár Czéh, Eberhard Fuchs, Wolfgang Brück, Christine Stadelman. Differential macrophage/microglia activation in neocortical EAE lesions in the marmoset monkey. Brain pathology (Zurich, Switzerland). vol 16. issue 2. 2006-09-21. PMID:16768751. |
in the present study we investigated the presence and detailed cellular composition of cortical inflammatory demyelinating pathology in the common marmoset upon immunization with myelin oligodendrocyte glycoprotein (mog). |
2006-09-21 |
2023-08-12 |
monkey |
| D Merkler, B Schmelting, B Czéh, E Fuchs, C Stadelmann, W Brüc. Myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the common marmoset reflects the immunopathology of pattern II multiple sclerosis lesions. Multiple sclerosis (Houndmills, Basingstoke, England). vol 12. issue 4. 2006-09-21. PMID:16900750. |
the present report shows that myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) in common marmoset monkeys reflects one specific lesional subtype of ms, namely ms pattern ii lesions with antibody/complement-mediated damage. |
2006-09-21 |
2023-08-12 |
monkey |
| Jorge Correale, Silvia N Tenembau. Myelin basic protein and myelin oligodendrocyte glycoprotein T-cell repertoire in childhood and juvenile multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). vol 12. issue 4. 2006-09-21. PMID:16900754. |
in order to gain further insight into the t-cell repertoire present in this particular group of patients myelin basic protein (mbp)-, mbp exon-2- and myelin oligodendrocyte glycoprotein (mog)igd-specific t-cell lines (tcls) were isolated from 18 patients whose symptoms had started before the age of 16. |
2006-09-21 |
2023-08-12 |
Not clear |
| Isabel Herrmann, Markus Kellert, Hauke Schmidt, Alexander Mildner, Uwe K Hanisch, Wolfgang Brück, Marco Prinz, Roland Na. Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infection and immunity. vol 74. issue 8. 2006-08-29. PMID:16861672. |
mice were immunized with myelin oligodendrocyte glycoprotein 35-55 (mog(35-55)) peptide, challenged intraperitoneally with live s. pneumoniae type 3, and then treated with ceftriaxone. |
2006-08-29 |
2023-08-12 |
mouse |
| Taizo Matsuki, Susumu Nakae, Katsuko Sudo, Reiko Horai, Yoichiro Iwakur. Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis. International immunology. vol 18. issue 2. 2006-08-23. PMID:16415102. |
to explore the role of the il-1/il-1ra system in autoimmune disease, we analyzed myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) in mice bearing targeted disruptions of the il-1alpha, il-1beta, il-1alpha and il-1beta (il-1) or il-1ra genes. |
2006-08-23 |
2023-08-12 |
mouse |