| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel P Ankeny, Phillip G Popovic. Central nervous system and non-central nervous system antigen vaccines exacerbate neuropathology caused by nerve injury. The European journal of neuroscience. vol 25. issue 7. 2007-06-21. PMID:17439492. |
prior to axotomy, c57bl/6 mice were immunized with myelin basic protein, myelin oligodendrocyte glycoprotein (mog) or ovalbumin (a non-self antigen) emulsified in complete freund's adjuvant (cfa). |
2007-06-21 |
2023-08-12 |
mouse |
| Koen Venken, Marielle Thewissen, Niels Hellings, Veerle Somers, Karen Hensen, Jean-Luc Rummens, Piet Stinisse. A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses. Journal of immunological methods. vol 322. issue 1-2. 2007-06-14. PMID:17368474. |
our results indicate that, in healthy individuals, cd4(+) t cell responses against the multiple sclerosis (ms) auto-antigens, myelin basic protein (mbp) and myelin oligodendrocyte glycoprotein (mog), were increased in treg depleted cd4(+) t cells as compared to total cd4(+) t cells. |
2007-06-14 |
2023-08-12 |
Not clear |
| Jillian E Adams, Matthew S Webb, Xianchen Hu, Don Staunton, Scott R Barnu. Disruption of the beta2-integrin CD11d (alphaDbeta2) gene fails to protect against experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 184. issue 1-2. 2007-06-01. PMID:17254640. |
we induced eae in wild-type and cd11d(-/-) c57bl/6 mice using myelin oligodendrocyte glycoprotein (mog(35-55)) peptide. |
2007-06-01 |
2023-08-12 |
mouse |
| Marina Zafranskaya, Patrick Oschmann, Rosel Engel, Andreas Weishaupt, Johannes M van Noort, Hassan Jomaa, Matthias Eber. Interferon-beta therapy reduces CD4+ and CD8+ T-cell reactivity in multiple sclerosis. Immunology. vol 121. issue 1. 2007-05-29. PMID:17239199. |
we assessed the prevalence and functional capacity of cd4+ and cd8+ t cells in healthy donors, and in untreated and ifn-beta-treated ms patients, in response to myelin oligodendrocyte glycoprotein (mog). |
2007-05-29 |
2023-08-12 |
Not clear |
| Nicolas Fazilleau, Cécile Delarasse, Iris Motta, Simon Fillatreau, Marie-Lise Gougeon, Philippe Kourilsky, Danielle Pham-Dinh, Jean M Kanellopoulo. T cell repertoire diversity is required for relapses in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 8. 2007-05-21. PMID:17404267. |
comparison of tcralphabeta repertoires of myelin oligodendrocyte glycoprotein (mog)-specific t lymphocytes in c57bl/6 and tdt-deficient littermates (tdt(-/-)) generated during experimental autoimmune encephalomyelitis (eae) highlights a link between a diversified tcralphabeta repertoire and eae relapses. |
2007-05-21 |
2023-08-12 |
mouse |
| Katharina Maier, Doron Merkler, Joachim Gerber, Naimeh Taheri, Antje V Kuhnert, Sarah K Williams, Clemens Neusch, Mathias Bähr, Ricarda Die. Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation. Neurobiology of disease. vol 25. issue 3. 2007-05-17. PMID:17239606. |
to investigate the effect of minocycline on the survival of retinal ganglion cells (rgcs), the neurons that form the axons of the optic nerve, we used a rat model of myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis. |
2007-05-17 |
2023-08-12 |
rat |
| Justin P Rubio, Melanie Bahlo, Jim Stankovich, Rachel K Burfoot, Laura J Johnson, Stewart Huxtable, Helmut Butzkueven, Ling Lin, Bruce V Taylor, Terence P Speed, Trevor J Kilpatrick, Emmanuel Mignot, Simon J Foot. Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients. Immunogenetics. vol 59. issue 3. 2007-05-08. PMID:17256150. |
complementary approaches were used to investigate residual predisposing effects of microsatellite alleles comprising the extended drb1*15 haplotype taking into account the strong predisposing effect of drb1*15: (1) disease association of the extended drb1*15 haplotype was compared for ms and narcolepsy families--predisposing effects were observed for extended class i microsatellite marker alleles in ms families, but not narcolepsy families; (2) disease association of the extended drb1*15 haplotype was investigated after conditioning ms and control haplotypes on the absence of drb1*15--a significant predisposing effect was observed for a 627-kb haplotype (d6s258 allele 8-mogca allele 4; mog, myelin oligodendrocyte glycoprotein) spanning the extended class i region. |
2007-05-08 |
2023-08-12 |
human |
| Kevin C O'Connor, Katherine A McLaughlin, Philip L De Jager, Tanuja Chitnis, Estelle Bettelli, Chenqi Xu, William H Robinson, Sunil V Cherry, Amit Bar-Or, Brenda Banwell, Hikoaki Fukaura, Toshiyuki Fukazawa, Silvia Tenembaum, Susan J Wong, Norma P Tavakoli, Zhannat Idrissova, Vissia Viglietta, Kevin Rostasy, Daniela Pohl, Russell C Dale, Mark Freedman, Lawrence Steinman, Guy J Buckle, Vijay K Kuchroo, David A Hafler, Kai W Wucherpfenni. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nature medicine. vol 13. issue 2. 2007-04-30. PMID:17237795. |
we developed a sensitive assay based on self-assembling radiolabeled tetramers that allows discrimination of antibodies against folded or denatured myelin oligodendrocyte glycoprotein (mog) by selective unfolding of the antigen domain. |
2007-04-30 |
2023-08-12 |
mouse |
| Jean-François Jégou, Philippe Chan, Marie-Thérèse Schouft, Mark R Griffiths, James W Neal, Philippe Gasque, Hubert Vaudry, Marc Fontain. C3d binding to the myelin oligodendrocyte glycoprotein results in an exacerbated experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 5. 2007-04-24. PMID:17312184. |
this study addresses the effect of c3d binding to the myelin oligodendrocyte glycoprotein (mog) in the induction of experimental autoimmune encephalomyelitis in c57bl/6j mice. |
2007-04-24 |
2023-08-12 |
mouse |
| Yinan Wang, Hirayasu Kai, Fei Chang, Kai Shibata, Satoko Tahara-Hanaoka, Shin-ichiro Honda, Akira Shibuya, Kazuko Shibuy. A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis. Biochemical and biophysical research communications. vol 353. issue 4. 2007-04-10. PMID:17207459. |
here, we demonstrate that the incidence and clinical scores of eae in lfa-1-/- mice induced by the immunization with the myelin oligodendrocyte glycoprotein (mog)-peptide antigen were significantly lower than those in wild type mice. |
2007-04-10 |
2023-08-12 |
mouse |
| Claire H Sweenie, Karen J Mackenzie, Alero Rone-Orugboh, Michael Liu, Stephen M Anderto. Distinct T cell recognition of naturally processed and cryptic epitopes within the immunodominant 35-55 region of myelin oligodendrocyte glycoprotein. Journal of neuroimmunology. vol 183. issue 1-2. 2007-04-05. PMID:17157925. |
we have assessed the complexity in t cell recognition of the immunodominant 35-55 region of myelin oligodendrocyte glycoprotein (mog) in c57bl/6 mice. |
2007-04-05 |
2023-08-12 |
mouse |
| Mehryar Zargari, Abdolamir Allameh, Mohammad Hossein Sanati, Taki Tiraihi, Shahram Lavasani, Omid Emadya. Relationship between the clinical scoring and demyelination in central nervous system with total antioxidant capacity of plasma during experimental autoimmune encephalomyelitis development in mice. Neuroscience letters. vol 412. issue 1. 2007-03-27. PMID:17157437. |
for this purpose, blood, brain and spinal cord samples from eae mice were collected and examined at different scores following post-immunization with myelin oligodendrocyte glycoprotein (mog). |
2007-03-27 |
2023-08-12 |
mouse |
| S J Pittock, M Reindl, S Achenbach, T Berger, W Bruck, F Konig, Y Morales, H Lassmann, S Bryant, S B Moore, B M Keegan, C F Lucchinett. Myelin oligodendrocyte glycoprotein antibodies in pathologically proven multiple sclerosis: frequency, stability and clinicopathologic correlations. Multiple sclerosis (Houndmills, Basingstoke, England). vol 13. issue 1. 2007-03-27. PMID:17294606. |
controversy exists regarding the pathogenic or predictive role of anti-myelin oligodendrocyte glycoprotein (mog) antibodies in patients with multiple sclerosis (ms). |
2007-03-27 |
2023-08-12 |
human |
| Ivana Zadro, Vesna Brinar, Gordana Horvat, Marko Brina. Clinical relevance of antibodies against myelin oligodendrocyte glycoprotein in different clinical types of multiple sclerosis. Clinical neurology and neurosurgery. vol 109. issue 1. 2007-03-20. PMID:16750597. |
myelin oligodendrocyte glycoprotein (mog) is a highly immunogenic minor component on the outside surface of cns myelin which is believed to be one of the autoantigens in multiple sclerosis. |
2007-03-20 |
2023-08-12 |
Not clear |
| Paresh Thakker, Michael W Leach, Wen Kuang, Stephen E Benoit, John P Leonard, Suzana Marusi. IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 4. 2007-03-20. PMID:17277169. |
in this study, we show that encephalitogenic t cells from myelin oligodendrocyte glycopeptide (mog)-immunized wild-type (wt) mice caused indistinguishable disease when adoptively transferred to wt or il-23-deficient (p19 knockout (ko)) recipient mice, demonstrating that once encephalitogenic cells have been generated, eae can develop in the complete absence of il-23. |
2007-03-20 |
2023-08-12 |
mouse |
| Yijun Carrier, Jing Yuan, Vijay K Kuchroo, Howard L Weine. Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 1. 2007-03-06. PMID:17182553. |
we found that repeated antigenic stimulation of pathogenic myelin oligodendrocyte glycoprotein (mog)-specific cd4(+)cd25(-) t cells from tgf-beta tg mice crossed to mog tcr-tg mice induced foxp3 expression in both cd25(+) and cd25(-) populations. |
2007-03-06 |
2023-08-12 |
mouse |
| Shinya Hirata, Hidetake Matsuyoshi, Daiki Fukuma, Akari Kurisaki, Yasushi Uemura, Yasuharu Nishimura, Satoru Senj. Involvement of regulatory T cells in the experimental autoimmune encephalomyelitis-preventive effect of dendritic cells expressing myelin oligodendrocyte glycoprotein plus TRAIL. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 2. 2007-02-22. PMID:17202353. |
we previously reported the protection from myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) by the adoptive transfer of genetically modified embryonic stem cell-derived dendritic cells (es-dc) presenting mog peptide in the context of mhc class ii molecules and simultaneously expressing trail (es-dc-trail/mog). |
2007-02-22 |
2023-08-12 |
mouse |
| Ikuo Tsunoda, Tomoko Tanaka, Emily Jane Terry, Robert S Fujinam. Contrasting roles for axonal degeneration in an autoimmune versus viral model of multiple sclerosis: When can axonal injury be beneficial? The American journal of pathology. vol 170. issue 1. 2007-02-21. PMID:17200195. |
in eae, both mouse strains were sensitized with myelin oligodendrocyte glycoprotein (mog)(35-55) peptide and showed a similar disease onset, mog-specific lymphoproliferative responses, and inflammation during the acute stage of eae. |
2007-02-21 |
2023-08-12 |
mouse |
| Jens Kuhle, Christoph Pohl, Matthias Mehling, Gilles Edan, Mark S Freedman, Hans-Peter Hartung, Chris H Polman, David H Miller, Xavier Montalban, Frederik Barkhof, Lars Bauer, Susanne Dahms, Raija Lindberg, Ludwig Kappos, Rupert Sandbrin. Lack of association between antimyelin antibodies and progression to multiple sclerosis. The New England journal of medicine. vol 356. issue 4. 2007-01-30. PMID:17251533. |
an increased risk of progression to clinically definite multiple sclerosis in patients with serum antibodies against myelin oligodendrocyte glycoprotein (mog) and myelin basic protein (mbp) has been reported. |
2007-01-30 |
2023-08-12 |
Not clear |
| Dun Zhou, Rajneesh Srivastava, Stefan Nessler, Verena Grummel, Norbert Sommer, Wolfgang Brück, Hans-Peter Hartung, Christine Stadelmann, Bernhard Hemme. Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 50. 2007-01-22. PMID:17142321. |
because of its location on the outer surface of the myelin sheath and its pathogenicity in the experimental autoimmune encephalomyelitis model, myelin oligodendrocyte glycoprotein (mog) is one of the potential disease-causing self antigens in ms. |
2007-01-22 |
2023-08-12 |
rat |