All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Natalia Dos Santos Tramontin, Sabrina da Silva, Rychard Arruda, Kellen Simon Ugioni, Paula Bortuluzzi Canteiro, Gustavo de Bem Silveira, Carolini Mendes, Paulo Cesar Lock Silveira, Alexandre Pastoris Mulle. Gold Nanoparticles Treatment Reverses Brain Damage in Alzheimer's Disease Model. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31612296. oa increases tau phosphorylation in the cortex and hippocampus, while aunp treatment maintained it as normal. 2020-11-25 2023-08-13 rat
Ryszard Pluta, Marzena Ułamek-Kozioł, Janusz Kocki, Jacek Bogucki, Sławomir Januszewski, Anna Bogucka-Kocka, Stanisław J Czuczwa. Expression of the Tau Protein and Amyloid Protein Precursor Processing Genes in the CA3 Area of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31713815. expression of the tau protein and amyloid protein precursor processing genes in the ca3 area of the hippocampus in the ischemic model of alzheimer's disease in the rat. 2020-11-25 2023-08-13 rat
Ryszard Pluta, Marzena Ułamek-Kozioł, Janusz Kocki, Jacek Bogucki, Sławomir Januszewski, Anna Bogucka-Kocka, Stanisław J Czuczwa. Expression of the Tau Protein and Amyloid Protein Precursor Processing Genes in the CA3 Area of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31713815. data show that brain ischemia activates neuronal changes and death in the ca3 region of the hippocampus in a manner dependent on amyloid and tau protein, thus determining a new and important way to regulate the survival and/or death of ischemic neurons. 2020-11-25 2023-08-13 rat
Brent Aulston, Qing Liu, Michael Mante, Jazmin Florio, Robert A Rissman, Shauna H Yua. Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain. Journal of Alzheimer's disease : JAD. vol 72. issue 2. 2020-11-17. PMID:31594233. moreover, fad ev injected hippocampi contained significantly more tau inclusions in the ca1 hippocampal neuronal field than controls. 2020-11-17 2023-08-13 mouse
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. brain derived neurotrophic factor (bdnf), synaptophysin, and tau hyperphosphorylation (t396) in the hippocampus were also examined. 2020-11-17 2023-08-13 mouse
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. following partial hepatectomy, the levels of phosphorylated mtor, phosphorylated 70s6k, and phosphorylated tau were all increased in the hippocampus. 2020-11-17 2023-08-13 mouse
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. rapamycin treatment restored autophagy function, attenuated phosphorylation of tau protein, and increased bdnf and synaptophysin expression in the hippocampus of surgical mice. 2020-11-17 2023-08-13 mouse
Mona Khalifa, Marwa M Safar, Rania M Abdelsalam, Hala F Zak. Telmisartan Protects Against Aluminum-Induced Alzheimer-like Pathological Changes in Rats. Neurotoxicity research. vol 37. issue 2. 2020-11-12. PMID:31332715. it reversed the increase in hippocampal amyloid beta protein, phosphorylated tau protein contents together with augmentation of neprilysin level, it also diminished levels of nuclear factor kappa-b, fas ligand, tumor necrosis factor-alpha, malondialdehyde, and acetylcholinesterase content.these findings show the protective action of telmisartan against ad-like pathological alterations. 2020-11-12 2023-08-13 rat
Yanchong Zhang, Feng Wu, Khalid Iqbal, Cheng-Xin Gong, Wen Hu, Fei Li. Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice. Scientific reports. vol 9. issue 1. 2020-11-10. PMID:30846870. we detected hyperphosphorylation of tau at multiple sites in ipsilateral hippocampus 6 weeks but not 7 months after cci. 2020-11-10 2023-08-13 mouse
Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. data show that brain ischemia activates neuronal changes and death in the hippocampus in a manner dependent on tau protein, thus determining a new and important way to regulate the survival and/or death of post-ischemic neurons. 2020-11-09 2023-08-13 Not clear
Arnaud Charil, Sergey Shcherbinin, Sudeepti Southekal, Michael D Devous, Mark Mintun, Melissa E Murray, Bradley B Miller, Adam J Schwar. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476153. worse performance on delayed recall was associated with increased hippocampal tau signal, and worse performance on the trail making test b-a was associated with lower values of the hippocampus to cortex ratio. 2020-11-05 2023-08-13 human
Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukaw. [Neuroprotective effects of the peel of Citrus kawachiensis (Kawachi Bankan) and auraptene in the hippocampus of hyperglycemia mice and global cerebral ischemia/reperfusion injury mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 155. issue 4. 2020-11-02. PMID:32612031. the c. kawachiensis treatment inhibited astroglial activation in the hippocampus and the hyperphosphorylation of tau protein in hippocampal neurons, and also relieved the suppression of neurogenesis in the dentate gyrus of the hippocampus in the type 2 diabetic db/db mice. 2020-11-02 2023-08-13 mouse
Océane Guillemaud, Kelly Ceyzériat, Thomas Saint-Georges, Karine Cambon, Fanny Petit, Lucile Ben Haim, Maria-Angeles Carrillo-de Sauvage, Martine Guillermier, Sueva Bernier, Anne-Sophie Hérard, Charlène Joséphine, Alexis Pierre Bémelmans, Emmanuel Brouillet, Philippe Hantraye, Gilles Bonvento, Carole Escarti. Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease. Neurobiology of aging. vol 90. 2020-10-29. PMID:32171592. we aimed to evaluate whether reactive astrocytes contribute to tau as well as amyloid pathologies in the hippocampus of 3xtg-ad mice, an ad model that develops tau hyper-phosphorylation and amyloid deposition. 2020-10-29 2023-08-13 mouse
Océane Guillemaud, Kelly Ceyzériat, Thomas Saint-Georges, Karine Cambon, Fanny Petit, Lucile Ben Haim, Maria-Angeles Carrillo-de Sauvage, Martine Guillermier, Sueva Bernier, Anne-Sophie Hérard, Charlène Joséphine, Alexis Pierre Bémelmans, Emmanuel Brouillet, Philippe Hantraye, Gilles Bonvento, Carole Escarti. Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease. Neurobiology of aging. vol 90. 2020-10-29. PMID:32171592. jak2-stat3 pathway-mediated modulation of reactive astrocytes in 25% of the hippocampus of 3xtg-ad mice did not significantly influence tau phosphorylation or amyloid processing and deposition at early, advanced, and terminal disease stage. 2020-10-29 2023-08-13 mouse
Anna L Svenningsson, Erik Stomrud, Philip S Insel, Niklas Mattsson, Sebastian Palmqvist, Oskar Hansso. β-amyloid pathology and hippocampal atrophy are independently associated with memory function in cognitively healthy elderly. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31371787. using cognition as outcome we studied the effects of cerebrospinal fluid biomarkers for amyloid-β (aβ42/40), neuroinflammation (ykl-40), and neurodegeneration and tau pathology (t-tau and p-tau) as well as mri measures of white-matter lesions, hippocampal volume (hv), and regional cortical thickness. 2020-10-27 2023-08-13 human
Juyong Kim, Siyoung Lee, Jaekyoon Kim, Sangwoo Ham, Jung Han Yoon Park, Seungbong Han, Yong-Keun Jung, Insop Shim, Jung-Soo Han, Ki Won Lee, Jiyoung Ki. Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer's disease. Human molecular genetics. vol 29. issue 2. 2020-10-19. PMID:31814000. we analyzed the animals' memory function, hippocampal ca2+ levels and amyloid-β (aβ) and tau pathologies when they were 12 months old. 2020-10-19 2023-08-13 mouse
Juyong Kim, Siyoung Lee, Jaekyoon Kim, Sangwoo Ham, Jung Han Yoon Park, Seungbong Han, Yong-Keun Jung, Insop Shim, Jung-Soo Han, Ki Won Lee, Jiyoung Ki. Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer's disease. Human molecular genetics. vol 29. issue 2. 2020-10-19. PMID:31814000. we found that compared with 3xtg-ad-/-/trpv1+/+ mice, 3xtg-ad+/+/trpv1+/+ mice had memory impairment and increased levels of hippocampal ca2+, aβ and total and phosphorylated tau. 2020-10-19 2023-08-13 mouse
Juyong Kim, Siyoung Lee, Jaekyoon Kim, Sangwoo Ham, Jung Han Yoon Park, Seungbong Han, Yong-Keun Jung, Insop Shim, Jung-Soo Han, Ki Won Lee, Jiyoung Ki. Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer's disease. Human molecular genetics. vol 29. issue 2. 2020-10-19. PMID:31814000. however, 3xtg-ad+/+/trpv1-/- mice had better memory function and lower levels of hippocampal ca2+, aβ, tau and p-tau, compared with 3xtg-ad+/+/trpv1+/+ mice. 2020-10-19 2023-08-13 mouse
Onder Albayram, Bryce MacIver, John Mathai, Anne Verstegen, Sean Baxley, Chenxi Qiu, Carter Bell, Barbara J Caldarone, Xiao Zhen Zhou, Kun Ping Lu, Mark Zeide. Traumatic Brain Injury-related voiding dysfunction in mice is caused by damage to rostral pathways, altering inputs to the reflex pathways. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:31201348. hyperphosphorylated tau deposition and neural tangle-like pathology occurred in cortical and hippocampal regions only of igg control mice accompanied with post-traumatic neuroinflammation and was not seen in midbrain and hindbrain regions associated with bladder filling and voiding reflex arcs. 2020-10-15 2023-08-13 mouse
Beibei Wu, Yujing Wang, Chenggang Shi, Yao Chen, Lexiang Yu, Juan Li, Weiwei Li, Yan Wei, Rongqiao H. Ribosylation-Derived Advanced Glycation End Products Induce Tau Hyperphosphorylation Through Brain-Derived Neurotrophic Factor Reduction. Journal of Alzheimer's disease : JAD. vol 71. issue 1. 2020-10-13. PMID:31381511. injections of rrsa were found to trigger tau hyperphosphorylation in the rat hippocampus via gsk-3β activation. 2020-10-13 2023-08-13 rat