Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J Albrecht, M Simmons, G R Dutton, M D Norenber. Aluminum chloride stimulates the release of endogenous glutamate, taurine and adenosine from cultured rat cortical astrocytes. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679221. |
primary astrocyte cultures derived from neonatal rat cerebral cortex were treated for 5 min with 0.5 mm or 5.0 mm alcl3, and the incubation medium was analyzed by hplc for the content of released glutamate (glu), taurine (tau), serine (ser) and the nucleoside adenosine (ade). |
1991-09-30 |
2023-08-11 |
rat |
M Puka, K Sundell, J W Lazarewicz, A Lehman. Species differences in cerebral taurine concentrations correlate with brain water content. Brain research. vol 548. issue 1-2. 1991-09-19. PMID:1868339. |
there was a correlation between these measures and cortical tau levels which were 10.31 +/- 0.36 mmol/kg in mouse cortex, 6.31 +/- 0.18 in rat cortex and 1.37 +/- 0.06 in guinea pig cortex. |
1991-09-19 |
2023-08-11 |
mouse |
S C Papasozomenos, Y S. Altered phosphorylation of tau protein in heat-shocked rats and patients with Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 10. 1991-06-25. PMID:1903545. |
in addition, quantitative immunoblot analysis of cortex and the underlying white matter with tau-1 and 125i-labeled protein a showed that the amount of phosphorylated tau progressively increased in the alzheimer disease-affected cerebral cortex, while concurrently a proportionally lesser amount of tau entered the white matter axons. |
1991-06-25 |
2023-08-11 |
rat |
G H Caines, T Schleich, C F Morgan, P N Farnswort. Off-resonance rotating frame spin-lattice NMR relaxation studies of phosphorus metabolite rotational diffusion in bovine lens homogenates. Biochemistry. vol 29. issue 33. 1991-02-25. PMID:2271517. |
values of tau 0,eff for phosphorus metabolites present in the cortex varied from a low of ca. |
1991-02-25 |
2023-08-11 |
cattle |
M Goedert, R Jake. Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization. The EMBO journal. vol 9. issue 13. 1991-02-14. PMID:2124967. |
four of these bands aligned with the major tau bands found in adult human cerebral cortex following perchloric acid extraction and alkaline phosphatase treatment. |
1991-02-14 |
2023-08-11 |
human |
D J Selko. Molecular pathology of amyloidogenic proteins and the role of vascular amyloidosis in Alzheimer's disease. Neurobiology of aging. vol 10. issue 5. 1989-12-18. PMID:2510035. |
antibodies to tau detect an extensive neuritic dystrophy in ad cerebral cortex that includes aberrant somatodendritic sprouting, suggesting a role for local growth-promoting molecules in the pathogenesis of ad. |
1989-12-18 |
2023-08-11 |
human |
C Viereck, R P Tucker, A Matu. The adult rat olfactory system expresses microtubule-associated proteins found in the developing brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 10. 1989-11-14. PMID:2507752. |
we have compared the expression and localization of neuronal microtubule-associated proteins (maps) map5, map2, and tau in the adult rat olfactory system and cerebral cortex. |
1989-11-14 |
2023-08-11 |
rat |
K S Kosik, J E Crandall, E J Mufson, R L Nev. Tau in situ hybridization in normal and Alzheimer brain: localization in the somatodendritic compartment. Annals of neurology. vol 26. issue 3. 1989-11-08. PMID:2508535. |
the distribution of the tau rna is abundant throughout the neuronal somata and into the proximal parts of dendrites of pyramidal cells in the cerebral cortex and the hippocampus. |
1989-11-08 |
2023-08-11 |
human |
P G Galloway, C Bergeron, G Perr. The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease. Neuroscience letters. vol 100. issue 1-3. 1989-09-15. PMID:2548130. |
the antigenic components of lewy bodies in the cerebral cortex and substantia nigra in 5 cases of diffuse lewy body disease were examined by immunocytochemistry, using antibodies to neurofilaments (in the phosphorylated or non-phosphorylated forms); to ubiquitin; to the microtubule-associated proteins map1, map2 and tau; to isolated alzheimer paired helical filaments, and to tubulin, in the tyrosinated and non-tyrosinated forms. |
1989-09-15 |
2023-08-11 |
Not clear |
P G Galloway, C Bergeron, G Perr. The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease. Neuroscience letters. vol 100. issue 1-3. 1989-09-15. PMID:2548130. |
immunoreactivity with antibodies to cytoskeletal components was identical to that previously described for lewy bodies of idiopathic parkinson disease, with the exception that the inclusions of diffuse lewy body disease (in both cortex and substantia nigra) were stained by an antibody to tau protein. |
1989-09-15 |
2023-08-11 |
Not clear |
H Murofushi, M Suzuki, H Sakai, S Kobayash. Immunohistochemical localization of microtubule-associated proteins in the nervous system of the small intestine of guinea pig. Cell and tissue research. vol 255. issue 2. 1989-05-11. PMID:2924335. |
layers containing auerbach's and meissner's plexuses were dissected from the small intestine of guinea pig and immunostained with affinity-purified antibodies against brain-specific microtubule-associated proteins (maps): map1, map2 and tau and a map with a molecular weight of 190,000 dalton purified from bovine adrenal cortex (190-kda map). |
1989-05-11 |
2023-08-11 |
cattle |
M Parent, A Delacourte, A Défossez, B Hémon, K K Han, H Peti. [Alzheimer's disease: study of the distribution of tau proteins constituting helical filament pairs in human central nervous tissue]. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. vol 306. issue 13. 1988-09-30. PMID:3136867. |
the normal cortical distribution of tau in the human brain correlates well with the distribution of histological lesions that contain phf (neurofibrillary tangles and neuritic plaques) in the alzheimer cortex. |
1988-09-30 |
2023-08-11 |
human |
A Defossez, J C Beauvillain, A Delacourte, M Mazzuc. Alzheimer's disease: a new evidence for common epitopes between microtubule associated protein Tau and paired helical filaments (PHF): demonstration at the electron microscope level by a double immunogold labelling. Virchows Archiv. A, Pathological anatomy and histopathology. vol 413. issue 2. 1988-08-05. PMID:2455379. |
two rabbit immune sera were used: one was raised against phf isolated from alzheimer cortex; the other against tau proteins extracted from bovine cortex. |
1988-08-05 |
2023-08-11 |
rabbit |
S C Papasozomenos, L I Binde. Phosphorylation determines two distinct species of Tau in the central nervous system. Cell motility and the cytoskeleton. vol 8. issue 3. 1988-02-20. PMID:2446784. |
treatment of immunoblots of extracts of whole cerebral cortex with phosphatase confirmed the immunohistochemical results in that a 50-65% increase in tau-1 binding to the tau region of the blot was noted. |
1988-02-20 |
2023-08-11 |
Not clear |
N W Kowall, K S Kosi. Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease. Annals of neurology. vol 22. issue 5. 1988-02-20. PMID:3122646. |
with optimal fixation and histochemical methods, we show the normal axonal location of tau protein in human cerebral cortex and the striking alterations of tau distribution that affect the cortical neuropil in alzheimer's disease. |
1988-02-20 |
2023-08-11 |
human |
T Jean, P Poujeol, P Ripoch. Taurine transport in brush border membrane vesicles isolated from hyper- and normotaurinuric mouse kidney. Renal physiology. vol 7. issue 6. 1985-01-18. PMID:6505373. |
transport studies performed in brush border membrane vesicles, isolated from c57bl and c3h mouse renal cortex, showed that d-glucose uptake was similar in both strains while the taurine uptake appeared to be faster in tau(+) than in tau(-) mice. |
1985-01-18 |
2023-08-12 |
mouse |
M A Rea, W J McBride, B H Rohd. Levels of glutamate, aspartate, GABA, and taurine in different regions of the cerebellum after x-irradiation-induced neuronal loss. Neurochemical research. vol 6. issue 1. 1981-06-23. PMID:7219665. |
the levels of glutamate (glu), aspartate (asp), gamma-amino-n-butyric acid (gaba), and taurine (tau) were determined in the cortex, molecular layer, and deep nuclei of cerebella of adult rats exposed to x-irradiation at 12-15 days following birth (to prevent the acquisition of late-forming granule cells; 12-15x group) and 8-15 days following birth (to prevent the acquisition of granule and stellate cells; 8-15x group). |
1981-06-23 |
2023-08-12 |
rat |