| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L A Olatunji, A O Soladoy. Increased magnesium intake prevents hyperlipidemia and insulin resistance and reduces lipid peroxidation in fructose-fed rats. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 14. issue 1. 2011-07-14. PMID:17187968. |
therefore, the present study investigated the influence of increasing dietary magnesium from 0.1% to 1.0% for 4 weeks on plasma lipids, lipid peroxidation, l-ascorbic acid and insulin sensitivity in male wistar rats fed a high-fructose diet. |
2011-07-14 |
2023-08-12 |
rat |
| L A Olatunji, A O Soladoy. Increased magnesium intake prevents hyperlipidemia and insulin resistance and reduces lipid peroxidation in fructose-fed rats. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 14. issue 1. 2011-07-14. PMID:17187968. |
homeostasis model assessment for insulin resistance (homa-ir) and plasma thiobarbituric acid-reactive substances (tbars) were used as indices of insulin sensitivity and lipid peroxidation, respectively. |
2011-07-14 |
2023-08-12 |
rat |
| Silvia Mirandola, David Bowman, Mahmood M Hussain, Alfredo Albert. Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP). Nutrition & metabolism. vol 7. 2011-07-14. PMID:20178560. |
in vivo and in vitro studies have shown that hcv can alter intrahepatic lipid metabolism by affecting lipid synthesis, oxidative stress, lipid peroxidation, insulin resistance and the assembly and secretion of vldl. |
2011-07-14 |
2023-08-12 |
Not clear |
| M Gayathri, K Kannabira. Effect of 2-Hydroxy-4-Methoxy Benzoic Acid from the Roots of Hemidesmus indicus on Streptozotocin-induced Diabetic Rats. Indian journal of pharmaceutical sciences. vol 71. issue 5. 2011-07-14. PMID:20502585. |
in our study, diabetic rats had increased levels of blood glucose and lipid peroxidation in plasma, erythrocytes and erythrocyte membrane and decreased level of plasma insulin and decreased activity of low affinity ca(2+) atpase in erythrocytes. |
2011-07-14 |
2023-08-12 |
rat |
| M Gayathri, K Kannabira. Effect of 2-Hydroxy-4-Methoxy Benzoic Acid from the Roots of Hemidesmus indicus on Streptozotocin-induced Diabetic Rats. Indian journal of pharmaceutical sciences. vol 71. issue 5. 2011-07-14. PMID:20502585. |
restoration of plasma insulin and glucose in diabetic rats indicates the effect of hmba on insulin, glucose and lipid peroxidation. |
2011-07-14 |
2023-08-12 |
rat |
| Parisa Sarkhail, Mohammad Abdollahi, Sedigheh Fadayevatan, Abbas Shafiee, Azadeh Mohammadirad, Gholamreza Dehghan, Hadi Esmaily, Gholamreza Ami. Effect of Phlomis persica on glucose levels and hepatic enzymatic antioxidants in streptozotocin-induced diabetic rats. Pharmacognosy magazine. vol 6. issue 23. 2011-07-14. PMID:20931083. |
(lamiaceae) (ppe) was studied to evaluate the effects of antidiabetic potential, by measuring fasting blood glucose, insulin, total antioxidant power (tap), using ferric reducing antioxidant power (frap), lipid peroxidation (using thiobarbituric acid reactive substances, tbars), superoxide dismutase (sod), catalase (cat), and glutathione peroxidase (gpx) on streptozotocin-induced diabetes in rats. |
2011-07-14 |
2023-08-12 |
rat |
| S Panda, A Ka. Periplogenin, isolated from Lagenaria siceraria, ameliorates L-T₄-induced hyperthyroidism and associated cardiovascular problems. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 43. issue 3. 2011-07-12. PMID:21287437. |
l-t₄ (500 μg/kg, s. c./d) administration for 12 days significantly increased serum concentrations of thyroxine (t₄), triidothyronine (t₃), and hepatic 5'-deiodinase i (5'-di) activity with a parallel increase in lipid peroxidation (lpo) in different organs such as heart, liver and kidney; serum glucose and insulin concentrations and a decrease in cardiac na (+)-k (+)-atpase activity as well as serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol and triglycerides. |
2011-07-12 |
2023-08-12 |
rat |
| S Panda, A Ka. Periplogenin, isolated from Lagenaria siceraria, ameliorates L-T₄-induced hyperthyroidism and associated cardiovascular problems. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 43. issue 3. 2011-07-12. PMID:21287437. |
however, out of its 3 different concentrations (5.0, 10, and 25 mg/kg), 5 mg/kg appeared to be the most effective one as it could nearly normalize the level of t₃, glucose, insulin, na (+)-k (+)-atpase activity, tissue lpo and different serum lipids suggesting the protective role of periplogenin against thyrotoxicosis and associated cardiovascular problems. |
2011-07-12 |
2023-08-12 |
rat |
| I A Volchegorskii, L M Rassokhina, I Yu Miroshnichenko, K M Mester, P N Novoselov, T V Astakhov. Effect of pro- and antioxidants on insulin sensitivity and glucose tolerance. Bulletin of experimental biology and medicine. vol 150. issue 3. 2011-05-20. PMID:21240346. |
we studied the correlation between the effect of α-lipoic acid, emoxipin, reamberin, and mexidol on lpo in vitro and the action of these drugs on insulin sensitivity and tolerance to glucose load in vivo. |
2011-05-20 |
2023-08-12 |
Not clear |
| Hafez R Madkor, Sherif W Mansour, Gamal Ramada. Modulatory effects of garlic, ginger, turmeric and their mixture on hyperglycaemia, dyslipidaemia and oxidative stress in streptozotocin-nicotinamide diabetic rats. The British journal of nutrition. vol 105. issue 8. 2011-05-19. PMID:21144104. |
the results showed that these spices and their mixture significantly alleviated (80-97 %, p < 0·05-0·001) signs of the metabolic syndrome (hyperglycaemia and dyslipidaemia), the elevation in atherogenic indices and cellular toxicity in stz-nicotinamide diabetic rats by increasing the production of insulin (26-37 %), enhancing the antioxidant defence system (31-52 %, especially gsh) and decreasing lipid peroxidation (60-97 %). |
2011-05-19 |
2023-08-12 |
rat |
| Tien-Hui Lu, Chin-Chuan Su, Ya-Wen Chen, Ching-Yao Yang, Chin-Ching Wu, Dong-Zong Hung, Chun-Hung Chen, Po-Wen Cheng, Shing-Hwa Liu, Chun-Fa Huan. Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways. Toxicology letters. vol 201. issue 1. 2011-03-30. PMID:21145380. |
we next observed that exposure of mice to ias in drinking water for 6 consecutive weeks significantly decreased decreased the plasma insulin, elevated glucose intolerance and plasma lipid peroxidation, and induced islet cells apoptosis, which accompanied with arsenic accumulation in the whole blood and pancreas. |
2011-03-30 |
2023-08-12 |
mouse |
| Yamini Dixit, Anand Ka. Protective role of three vegetable peels in alloxan induced diabetes mellitus in male mice. Plant foods for human nutrition (Dordrecht, Netherlands). vol 65. issue 3. 2011-01-31. PMID:20614191. |
at the end, alterations in serum glucose, insulin, triiodothyronine, thyroxine, total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, very low density lipoprotein, hepatic lipid peroxidation, superoxide dismutase and catalase were studied. |
2011-01-31 |
2023-08-12 |
mouse |
| Rameshwar Jatwa, Anand Ka. Effect of metformin on renal microsomal proteins, lipid peroxidation and antioxidant status in dexamethasone-induced type-2 diabetic mice. Indian journal of biochemistry & biophysics. vol 47. issue 1. 2010-12-10. PMID:21086754. |
while dexamethasone administration (1.0 mg/kg for 21 days) expressed two renal proteins (43 kda and 63.23 kda), in addition to the increased fasting serum levels of glucose and insulin, renal lpo, rsi and daily rate of water consumption, a parallel decrease in renal sod, cat and gsh was also observed. |
2010-12-10 |
2023-08-12 |
mouse |
| b' G A Pusyreva, V K Frolkov, I P Bobrovnitski\\xc4\\xa. [Metabolic mechanisms underlying reparative action of metal-dependent spectral light flux from a hollow cathode lamp (experimental study)]. Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury. issue 3. 2010-10-27. PMID:20734864.' |
specifically, it accelerated reduction of the wound surface area and optimized regulation of carbohydrate metabolism in the lipid peroxidation system by insulin and cotisol. |
2010-10-27 |
2023-08-12 |
Not clear |
| Tânia Regina Beraldo Battistini, Roseli Oselka Saccardo Sarni, Fabíola Isabel Suano de Souza, Tassiana Sacchi Pitta, Ana Paula Fernandes, Sonia Hix, Fernando Luiz Affonso Fonseca, Priscila Chemiotti Tardini, Valter Pinho dos Santos, Fábio Ancona Lope. Lipodystrophy, lipid profile changes, and low serum retinol and carotenoid levels in children and adolescents with acquired immunodeficiency syndrome. Nutrition (Burbank, Los Angeles County, Calif.). vol 26. issue 6. 2010-10-12. PMID:20116215. |
to assess serum retinol and levels of carotenoids in children and adolescents with acquired immunodeficiency syndrome (aids) and to correlate low serum retinol and carotenoid levels with the presence of lipodystrophy, lipid profile changes, lipid peroxidation, and insulin resistance. |
2010-10-12 |
2023-08-12 |
Not clear |
| Ming Tong, Alexander Neusner, Lisa Longato, Margot Lawton, Jack R Wands, Suzanne M de la Mont. Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 17. issue 4. 2010-09-22. PMID:20387270. |
ndea treatment caused t2dm, nash, deficits in motor function and spatial learning, and neurodegeneration characterized by insulin resistance and deficiency, lipid peroxidation, cell loss, increased levels of amyloid-beta protein precursor/amyloid-beta, phospho-tau, and ubiquitin immunoreactivities, and upregulated expression of pro-inflammatory cytokine and pro-ceramide genes, which together promote insulin resistance. |
2010-09-22 |
2023-08-12 |
human |
| Brent A Neuschwander-Tetr. Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. Hepatology (Baltimore, Md.). vol 52. issue 2. 2010-09-07. PMID:20683968. |
once thought to be a disease caused by triglyceride accumulation in hepatocytes with subsequent oxidant stress and lipid peroxidation causing inflammation and fibrosis, new data from animal studies and a limited number of human studies now provide convincing evidence that triglyceride accumulation does not cause insulin resistance or cellular injury in the liver. |
2010-09-07 |
2023-08-12 |
human |
| Fangdi Hu, Xiaodong Li, Lianggong Zhao, Shilan Feng, Chunming Wan. Antidiabetic properties of purified polysaccharide from Hedysarum polybotrys. Canadian journal of physiology and pharmacology. vol 88. issue 1. 2010-08-31. PMID:20130740. |
therefore, these results suggest that hps3 may partly ameliorate hyperglycemia and hyperlipidemia associated with type 2 diabetes through increased insulin secretion, inhibition of lipid peroxidation, promotion of sensitivity to insulin, suppression of gluconeogenesis and reduction in the biosynthesis fatty acid, cholesterol and cell cytokines related to insulin resistance, and it could be a useful adjunct therapy to a proven first-line therapy for type 2 diabetes using metformin. |
2010-08-31 |
2023-08-12 |
mouse |
| Wu Li, Yong-hui Shi, Rui-li Yang, Jue Cui, Ying Xiao, Bin Wang, Guo-wei L. Effect of somatostatin analog on high-fat diet-induced metabolic syndrome: involvement of reactive oxygen species. Peptides. vol 31. issue 4. 2010-07-01. PMID:19931331. |
plasma lipid, glucose, insulin, sst, the levels of ros and gsh/gssg, and lipid peroxidation in the stomach, small intestine, pancreas, and liver were also evaluated. |
2010-07-01 |
2023-08-12 |
mouse |
| Yan Li, Lijuan Xu, Jie Shen, Jianmin Ran, Yang Zhang, Min Wang, Li Yan, Hua Cheng, Zuzhi F. Effects of short-term therapy with different insulin secretagogues on glucose metabolism, lipid parameters and oxidative stress in newly diagnosed Type 2 Diabetes Mellitus. Diabetes research and clinical practice. vol 88. issue 1. 2010-06-28. PMID:20060192. |
to compare effects of three different insulin secretagogues on early-phase insulin secretion, metabolism of glucose and lipids, and lipid peroxidation in newly diagnosed type 2 diabetes mellitus (t2dm). |
2010-06-28 |
2023-08-12 |
Not clear |