| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Apoorva Sethi, Hamendra S Parmar, Anil Kuma. The effect of aspirin on atherogenic diet-induced diabetes mellitus. Basic & clinical pharmacology & toxicology. vol 108. issue 6. 2012-01-09. PMID:21205219. |
in response to cct diet, a decrease in serum insulin, α-amylase activity, hepatic glycogen, pancreatic calcium with a concomitant increase in serum glucose, lipid profile (except high-density lipoprotein cholesterol (hdl-c)), pancreatic nitrite and lipid peroxidation and the size of adipocytes along with macrophages infiltration were observed. |
2012-01-09 |
2023-08-12 |
rat |
| Apoorva Sethi, Hamendra S Parmar, Anil Kuma. The effect of aspirin on atherogenic diet-induced diabetes mellitus. Basic & clinical pharmacology & toxicology. vol 108. issue 6. 2012-01-09. PMID:21205219. |
in experiment 2, aspirin administration decreased the serum glucose, total cholesterol, triglycerides, low-density lipoprotein cholesterol (ldl-c) and vldl-c with concomitantly increased hdl-c and insulin; however, it increased hepatic glycogen and pancreatic calcium concentration with a decrease in pancreatic and adipose lipid peroxidation. |
2012-01-09 |
2023-08-12 |
rat |
| Chinnapaiyan Srinivasan, Adam Ismail Khan, Venkataraman Balaji, Jayaraman Selvaraj, Karundevi Balasubramania. Diethyl hexyl phthalate-induced changes in insulin signaling molecules and the protective role of antioxidant vitamins in gastrocnemius muscle of adult male rat. Toxicology and applied pharmacology. vol 257. issue 2. 2012-01-09. PMID:21911000. |
the present study suggests that dehp exposure affects glucose oxidation in skeletal muscle and is mediated through enhanced lipid peroxidation, impaired insulin signaling and glut4 expression in plasma membrane. |
2012-01-09 |
2023-08-12 |
human |
| P Pettinelli, A M Obregón, L A Videl. Molecular mechanisms of steatosis in nonalcoholic fatty liver disease. Nutricion hospitalaria. vol 26. issue 3. 2012-01-06. PMID:21892559. |
however, metabolic changes such as insulin resistance (ir) are developed, being a common factor in the retention of fatty acids (fa) within the hepatocytes with oxidation and production of free radicals at the mitochondrial level, which are capable of causing lipid peroxidation, cytokine production, and necrosis. |
2012-01-06 |
2023-08-12 |
Not clear |
| Sangbin Lim, Hyeran Won, Yeonghwan Kim, Miran Jang, K R Jyothi, Youngseol Kim, Paresh Dandona, Joohun Ha, Sung Soo Ki. Antioxidant enzymes induced by repeated intake of excess energy in the form of high-fat, high-carbohydrate meals are not sufficient to block oxidative stress in healthy lean individuals. The British journal of nutrition. vol 106. issue 10. 2012-01-03. PMID:21676280. |
repeated intake of hfhc meals induced cellular antioxidant mechanisms, which in turn increased lipid peroxidation (mda) and socs-3 expression levels, induced hyperinsulinaemia and increased homa-ir, an index of insulin resistance. |
2012-01-03 |
2023-08-12 |
Not clear |
| Guy Cohen, Yael Riahi, Ofer Shamni, Michel Guichardant, Chryssostomos Chatgilialoglu, Carla Ferreri, Nurit Kaiser, Shlomo Sasso. Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion. Diabetes. vol 60. issue 11. 2011-12-14. PMID:21896929. |
role of lipid peroxidation and ppar-δ in amplifying glucose-stimulated insulin secretion. |
2011-12-14 |
2023-08-12 |
Not clear |
| Chin-Shiu Huang, Mei-Chin Yin, Lan-Chi Chi. Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 9. 2011-12-07. PMID:21679740. |
mechanistically, pg protected pancreatic tissues, including islet β-cells, against lipid peroxidation and dna strand breaks induced by stz, and thus reduced the loss of insulin-positive β-cells and insulin secretion. |
2011-12-07 |
2023-08-12 |
rat |
| Amr M Abbas, Ayman Z Elsamanoud. Effects of 17β-estradiol and antioxidant administration on oxidative stress and insulin resistance in ovariectomized rats. Canadian journal of physiology and pharmacology. vol 89. issue 7. 2011-11-29. PMID:21812527. |
therefore, we investigated the effects of 17β-estradiol (e(2)) and vitamin e, as an antioxidant, on lipid peroxidation and antioxidant levels in the brain cortex and liver of ovariectomized rats as well as on insulin resistance in those rats. |
2011-11-29 |
2023-08-12 |
rat |
| Amr M Abbas, Ayman Z Elsamanoud. Effects of 17β-estradiol and antioxidant administration on oxidative stress and insulin resistance in ovariectomized rats. Canadian journal of physiology and pharmacology. vol 89. issue 7. 2011-11-29. PMID:21812527. |
this study demonstrates that e(2) and e(2) plus vitamin e supplementation to ovx rats may improve insulin resistance, strengthen the antioxidant system, and reduce lipid peroxidation. |
2011-11-29 |
2023-08-12 |
rat |
| Ramesh Bellamkonda, Karuna Rasineni, Sreenivasa Reddy Singareddy, Ramesh Babu Kasetti, Ramatholisamma Pasurla, Appa Rao Chippada, Saralakumari Desiredd. Antihyperglycemic and antioxidant activities of alcoholic extract of Commiphora mukul gum resin in streptozotocin induced diabetic rats. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 18. issue 4. 2011-11-10. PMID:21767936. |
the present study investigated the effect of commiphora mukul ethanol extract gum resin (cmeet) on streptozotocin (stz) induced diabetic rats by measuring fasting blood glucose, plasma insulin, plasma lipid profile, atherogenic index, hepatic lipid peroxidation (lpo), protein oxidation (po) and activities of enzymatic antioxidants. |
2011-11-10 |
2023-08-12 |
rat |
| Yara Haddad, Diane Vallerand, Antoine Brault, Jean Spénard, Pierre S Hadda. NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA. International journal of hepatology. vol 2011. 2011-11-10. PMID:22013536. |
treatments with n30 improved liver histology, decreased lipid peroxidation, and completely suppressed increases in ldh release, plasma insulin, and tnf-α. |
2011-11-10 |
2023-08-12 |
rat |
| Giridhar Kanuri, Astrid Spruss, Sabine Wagnerberger, Stephan C Bischoff, Ina Berghei. Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice. The Journal of nutritional biochemistry. vol 22. issue 6. 2011-10-21. PMID:20801629. |
furthermore, lipid peroxidation and indices of insulin resistance were determined in liver tissue and plasma. |
2011-10-21 |
2023-08-12 |
mouse |
| Rosa María Vigueras-Villaseñor, Julio César Rojas-Castañeda, Margarita Chávez-Saldaña, Oscar Gutiérrez-Pérez, Mercedes Edna García-Cruz, Osvaldo Cuevas-Alpuche, Marcos Manuel Reyes-Romero, Elena Zambran. Alterations in the spermatic function generated by obesity in rats. Acta histochemica. vol 113. issue 2. 2011-10-10. PMID:20149418. |
in order to assess the effect of obesity on epididymal and germinal epithelia in control rats and obese rats induced by a high fat diet, we evaluated the epididymal and testicular morphologies, lipid peroxidation in the epididymis, leptin serum levels, steroid hormones, insulin, cholesterol, triglycerides, glycemia and some spermatobioscopic parameters. |
2011-10-10 |
2023-08-12 |
rat |
| Nicolas J Pillon, Roxane E Vella, Laurent Souleere, Michel Becchi, Michel Lagarde, Christophe O Soulag. Structural and functional changes in human insulin induced by the lipid peroxidation byproducts 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal. Chemical research in toxicology. vol 24. issue 5. 2011-09-09. PMID:21462967. |
structural and functional changes in human insulin induced by the lipid peroxidation byproducts 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal. |
2011-09-09 |
2023-08-12 |
mouse |
| Shallu Gupta, Tarun Kumar Sharma, G G Kaushik, V P S Shekhawa. Vitamin E supplementation may ameliorate oxidative stress in type 1 diabetes mellitus patients. Clinical laboratory. vol 57. issue 5-6. 2011-08-09. PMID:21755829. |
in this study we evaluated oxidative stress in type 1 diabetes mellitus (insulin dependent diabetes mellitus, iddm) patients by estimating lipid peroxidation and the effect of vitamin e on oxidative stress and metabolic parameters. |
2011-08-09 |
2023-08-12 |
Not clear |
| Iu I Ragino, A M Cherniavskiĭ, N V Eremenko, E V Shakhtshneĭder, Ia V Polonskaia, S Iu Tsymbal, M V Ivanova, M I Voevod. [Key laboratory diagnostic biomarkers of coronary atherosclerosis]. Kardiologiia. vol 51. issue 3. 2011-07-27. PMID:21627612. |
laboratory lipid and lipoprotein biomarkers (total cholesterol - ch, triglycerides - tg, low-density and high-density lipoprotein cholesterol- ldl-ch, hdl-ch, apolipoproteins b and a1 - apob, apoa1), carbohydrate biomarkers (plasma glucose, basal insulin), high sensitive c-reactive protein (hscrp) and oxidative biomarkers (basal level of lipid peroxidation [lpo] products in ldl, ldl resistance to oxidation in vitro, oxidative modification of apoldl and level of ldl lipophilic antioxidants) were studied in 388 men aged 42-70 years: 96 citizens of western siberia with angiographically documented coronary atherosclerosis and coronary heart disease (chd); 292 men of population sample of citizens of novosibirsk, including 44 men with chd confirmed by standardized criteria and methods. |
2011-07-27 |
2023-08-12 |
Not clear |
| Iu I Ragino, A M Cherniavskiĭ, N V Eremenko, E V Shakhtshneĭder, Ia V Polonskaia, S Iu Tsymbal, M V Ivanova, M I Voevod. [Key laboratory diagnostic biomarkers of coronary atherosclerosis]. Kardiologiia. vol 51. issue 3. 2011-07-27. PMID:21627612. |
significant associations were found of coronary atherosclerosis and chd with laboratory diagnostic biomarkers like blood levels of hdl-ch, tg, apob, apoa1, basal insulin, hscrp and basal level of lpo products in ldl and ldl resistance to oxidation. |
2011-07-27 |
2023-08-12 |
Not clear |
| Chandrasekaran Sankaranarayanan, Leelavinothan Par. Thymoquinone ameliorates chemical induced oxidative stress and β-cell damage in experimental hyperglycemic rats. Chemico-biological interactions. vol 190. issue 2-3. 2011-07-26. PMID:21382363. |
the present study was aimed to investigate the effect of thymoquinone (tq) on pancreatic insulin levels, tissue antioxidant and lipid peroxidation (lpo) status in streptozotocin (stz) nicotinamide (na) induced diabetic rats. |
2011-07-26 |
2023-08-12 |
rat |
| V R Punithavathi, P Stanely Mainzen Prince, M R Kumar, C J Selvakumar. Protective effects of gallic acid on hepatic lipid peroxide metabolism, glycoprotein components and lipids in streptozotocin-induced type II diabetic Wistar rats. Journal of biochemical and molecular toxicology. vol 25. issue 2. 2011-07-25. PMID:21472896. |
streptozotocin-induced diabetic rats showed a significant increase in the levels of blood glucose, hepatic lipid peroxidation products, glycoprotein components, lipids, and the activity of hmg-coa reductase and a significant decrease in the levels of plasma insulin and liver glycogen. |
2011-07-25 |
2023-08-12 |
rat |
| L A Olatunji, A O Soladoy. Increased magnesium intake prevents hyperlipidemia and insulin resistance and reduces lipid peroxidation in fructose-fed rats. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 14. issue 1. 2011-07-14. PMID:17187968. |
increased magnesium intake prevents hyperlipidemia and insulin resistance and reduces lipid peroxidation in fructose-fed rats. |
2011-07-14 |
2023-08-12 |
rat |