| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marjan Mahdavi-Roshan, Nargeskhatoon Shoaibinobarian, Mehdi Evazalipour, Arsalan Salari, Zeinab Ghorbani, Amir Savarrakhsh, Zahra Ahmadni. An open label randomized controlled trial of the effects of rice bran oil on cardiometabolic risk factors, lipid peroxidation and antioxidant status in overweight/obese adults with metabolic syndrome. Lipids in health and disease. vol 23. issue 1. 2024-08-29. PMID:39198792. |
therefore, the existing evidence in this area aims to be expanded by investigating the impact of adding rbo to a daily standard diet on emerging insulin resistance surrogate markers, lipid peroxidation, antioxidant status, and metabolic disturbances in individuals with metabolic syndrome (metsyn) through an open-label controlled trial. |
2024-08-29 |
2024-09-01 |
Not clear |
| Qi Gao, Yingying Jiang, Zhenqiang Song, Huizhu Ren, Yan Kong, Cong Wang, Miaoyan Zheng, Chunyan Shan, Yanhui Yan. Dapagliflozin improves skeletal muscle insulin sensitivity through SIRT1 activation induced by nutrient deprivation state. Scientific reports. vol 14. issue 1. 2024-07-23. PMID:39043740. |
lipid peroxidation and mitochondrial damage impair insulin sensitivity in skeletal muscle. |
2024-07-23 |
2024-07-26 |
mouse |
| Nawel Kaddour, Farah Benyettou, Kawtar Moulai, Abdelouahab Mebarki, Katia Allal-Taouli, Rose Ghemrawi, Jamie Whelan, Hafida Merzouk, Ali Trabolsi, Nassima Amel Mokhtari-Souliman. Effects of subcutaneous vs. oral nanoparticle-mediated insulin delivery on hemostasis disorders in type 1 diabetes: A rat model study. Heliyon. vol 10. issue 9. 2024-05-08. PMID:38711655. |
traditional subcutaneous insulin injections exacerbated hemostasis disorder and vascular injuries in streptozotocin (stz)-induced diabetic rats through increasing plasma triglycerides and lipid peroxidation. |
2024-05-08 |
2024-05-27 |
rat |
| Enas A Saad, Hanaa A Hassan, Mamdooh H Ghoneum, Mai Alaa El-Dei. Edible wild plants, chicory and purslane, alleviated diabetic testicular dysfunction, and insulin resistance via suppression 8OHdg and oxidative stress in rats. PloS one. vol 19. issue 4. 2024-04-11. PMID:38603728. |
according to the collected data, the daily administration of chicory (ch) seed-extract (250 mg/kg) or purslane (pu) seed-extract (200 mg/kg) to streptozotocin (stz)-induced diabetic rats (50 mg/kg) for 30 days resulted in the normalization of fasting blood glucose (fbg), serum fructosamine, insulin levels, and insulin resistance (homa-ir), as well as reducing lipid peroxidation end-product malondialdehyde (mda) level, aldehyde oxidase (ao) and xanthene oxidase (xo) activities. |
2024-04-11 |
2024-04-14 |
rat |
| Biljana Bursać, Luisa Bellachioma, Ljupka Gligorovska, Mirna Jovanović, Ana Teofilović, Miloš Vratarić, Danijela Vojnović Milutinović, Alfonso Albacete, Purificación A Martínez-Melgarejo, Camilla Morresi, Elisabetta Damiani, Tiziana Bacchetti, Ana Djordjevi. Crocus sativus tepals extract suppresses subcutaneous adipose tissue hypertrophy and improves systemic insulin sensitivity in mice on high-fat diet. BioFactors (Oxford, England). 2024-02-06. PMID:38318672. |
the animal model confirmed that oral treatment with cr tepals extract results in weight loss, improved systemic insulin sensitivity, lower triglycerides, and improved lipid peroxidation. |
2024-02-06 |
2024-02-09 |
mouse |
| Angélica Marchesi Lira-Meriguete, Mayara Paes Santos, Vivian Cerqueira de Souza Viana, Nadmy Arrivabene Zavaris Gonçalves, Rodrigo Rezende Kitagawa, Lorena Carnielli-Queiroz, Daniela Amorim Melgaço Guimarães do Bem, Rita de Cássia Ribeiro Gonçalve. Can pharmaceutical care decrease the oxidative stress in type 2 diabetes mellitus? Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 171. 2024-01-24. PMID:38266624. |
therefore, the aim of this study was to evaluate whether pharmacotherapeutic follow-up in patients with t2d, users and non-users of insulin, interferes with the levels of oxidative stress, measuring lipid peroxidation and protein oxidation, nitric oxide and superoxide dismutase levels. |
2024-01-24 |
2024-01-27 |
Not clear |
| Bassel Eldeen Makki, Sarah Rahma. Alzheimer's Disease in Diabetic Patients: A Lipidomic Prospect. Neuroscience. 2023-08-31. PMID:37652288. |
insulin resistance is the tipping point beyond where advanced glycation end (age) products and free radicals are produced leading to oxidative stress and lipid peroxidation. |
2023-08-31 |
2023-09-07 |
Not clear |
| J M C R J Bertoldi, R Kindlovits, H N M Rocha, C Fernandes-Santos, J L P Gomes, E M Oliveira, I C Muniz, M M Santos, J F Pereira, N G Rocha, A C L da Nóbrega, R F Medeiro. Aerobic exercise prevents cardiomyocyte damage caused by oxidative stress in early cardiovascular disease by increasing vascularity while L-arginine supplementation prevents it by increasing activation of the enzyme nitric oxide synthase. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 56. 2023-08-16. PMID:37585913. |
body composition, blood glucose, insulin, lipid profile, lipid peroxidation, nitrite, metalloproteinase-2 (mmp-2) activity, left ventricle histological changes, microrna-126, -195, and -146, enos, p-enos, and tnf-α expressions were analyzed. |
2023-08-16 |
2023-09-07 |
rat |
| Miao Sun, Yang Li, Min Liu, Qingxiao Li, Likai Shi, Xianghan Ruan, Yuting Huo, Zhikang Zhou, Xiaoying Zhang, Yulong Ma, Weidong M. Insulin alleviates lipopolysaccharide-induced cognitive impairment via inhibiting neuroinflammation and ferroptosis. European journal of pharmacology. 2023-07-21. PMID:37479016. |
furthermore, insulin treatment inhibited lps-induced ferroptosis in the hippocampus by decreasing iron accumulation levels, regulating ferroptosis-related proteins including transferrin, glutathione peroxidase 4 (gpx4), ferritin heavy chin 1 (fth1) and cystine/glutamate antiporter (xct), inhibiting oxidative stress injuries and lipid peroxidation in the hippocampus. |
2023-07-21 |
2023-08-14 |
Not clear |
| Chan Hum Park, Jeong Sook Noh, Jin Pyeong Jeon, Takako Yokozaw. A systematic review on anti-diabetic action of 7-O-galloyl-D-sedoheptulose, a polyphenol from Corni Fructus, in type 2 diabetic mice with hepatic and pancreatic damage. Drug discoveries & therapeutics. 2023-05-28. PMID:37245985. |
in addition, gs suppressed the reactive oxygen species and lipid peroxidation in the serum, liver, and pancreas, but increased the pancreatic insulin and pancreatic c-peptide contents. |
2023-05-28 |
2023-08-14 |
mouse |
| Gabriela Maturana, Javiera Segovia, Claudio Olea-Azar, Ernesto Uribe-Oporto, Alejandra Espinosa, María Carolina Zúñiga-Lópe. Evaluation of the Effects of Chia ( Antioxidants (Basel, Switzerland). vol 12. issue 5. 2023-05-27. PMID:37237974. |
results show that the chia leaf extract positively affected insulin resistance and lipid peroxidation in the liver. |
2023-05-27 |
2023-08-14 |
mouse |
| Nursarah Syamimi Anuar, Syahirah Ain Shafie, Muhammad Aiman Faris Maznan, Noor Syaffinaz Noor Mohamad Zin, Nur Ain Sabrina Azmi, Rohaizad Abdul Raoof, Diyas Myrzakozha, Nurdiana Samsulriza. Lauric acid improves hormonal profiles, antioxidant properties, sperm quality and histomorphometric changes in testis and epididymis of streptozotocin-induced diabetic infertility rats. Toxicology and applied pharmacology. 2023-05-21. PMID:37211320. |
hormonal profiles (insulin and testosterone), lipid peroxidation (mda) and antioxidant enzyme (sod and cat) activities were measured in the serum, testis and epididymis. |
2023-05-21 |
2023-08-14 |
rat |
| Temitope Gabriel Adedeji, Sikirullai Olatunde Jeje, Tosan Peter Omayone, Boluwatife Olamide Dareowolab. Soda intake influences phenotype, antioxidants and inflammatory status in high protein-fed wistar rats. Heliyon. vol 9. issue 5. 2023-05-15. PMID:37180936. |
body measurements, blood glucose levels, serum insulin levels, lipid peroxidation, antioxidant activity, adipokines and inflammatory markers concentrations were all determined. |
2023-05-15 |
2023-08-14 |
rat |
| Qiyou Tan, Bin Wang, Zi Ye, Ge Mu, Wei Liu, Xiuquan Nie, Linling Yu, Min Zhou, Weihong Che. Cross-sectional and longitudinal relationships between ozone exposure and glucose homeostasis: Exploring the role of systemic inflammation and oxidative stress in a general Chinese urban population. Environmental pollution (Barking, Essex : 1987). 2023-04-26. PMID:37100372. |
fasting plasma glucose (fpg), insulin (fpi), plasma c-reactive protein (crp, biomarker for systemic inflammation), urinary 8-hydroxy-2'-deoxyguanosine (8-ohdg, biomarker for oxidative dna damage), and 8-isoprostane (biomarker for lipid peroxidation) were repeatedly measured. |
2023-04-26 |
2023-08-14 |
Not clear |
| Amira E Farage, Walied Abdo, Amira Osman, Mona A Abdel-Kareem, Zaki H Hakami, Ahmad Alsulimani, Albandari Bin-Ammar, Ashwag S Alanazi, Bader Alsuwayt, Mohammed M Alanazi, Samar A Antar, Emadeldin M Kamel, Ayman M Mahmou. Betulin prevents high fat diet-induced non-alcoholic fatty liver disease by mitigating oxidative stress and upregulating Nrf2 and SIRT1 in rats. Life sciences. 2023-04-08. PMID:37030617. |
hfd caused hyperlipidemia, cholesterol and triglycerides accumulation in the liver, hepatocellular ballooning, fibrosis, insulin resistance (ir), lipid peroxidation (lpo), and nf-kb p65 upregulation. |
2023-04-08 |
2023-08-14 |
rat |
| Amira E Farage, Walied Abdo, Amira Osman, Mona A Abdel-Kareem, Zaki H Hakami, Ahmad Alsulimani, Albandari Bin-Ammar, Ashwag S Alanazi, Bader Alsuwayt, Mohammed M Alanazi, Samar A Antar, Emadeldin M Kamel, Ayman M Mahmou. Betulin prevents high fat diet-induced non-alcoholic fatty liver disease by mitigating oxidative stress and upregulating Nrf2 and SIRT1 in rats. Life sciences. 2023-04-08. PMID:37030617. |
be ameliorated serum and liver lipids, blood glucose, and insulin, liver lpo, prevented steatosis and fibrosis, suppressed nf-kb p65 and enhanced antioxidants in hfd-fed rats. |
2023-04-08 |
2023-08-14 |
rat |
| Adewumi Oluwafemi Oyabambi, Kehinde Samuel Olaniy. Sodium butyrate aggravates glucose dysregulation and dyslipidemia in high fat-fed Wistar rats. Metabolism open. vol 17. 2023-01-06. PMID:36606023. |
sodium butyrate significantly decreased circulating nitric oxide (no) and ld while increasing ffa, tg, insulin resistance, aggravated lipid peroxidation and increased vegf in hfd rats (p < 0.05). |
2023-01-06 |
2023-08-14 |
rat |
| Ingrid Rivera-Iñiguez, Arturo Panduro, Sonia Roman, Karina González-Aldac. What do we know about nutrient-based strategies targeting molecular mechanisms associated with obesity-related fatty liver disease?: Running Title: Nutrient-based strategies and NAFLD. Annals of hepatology. 2022-11-12. PMID:36371078. |
obesity facilitates the onset of insulin resistance, lipidic abnormalities, hepatic fat accumulation, lipid peroxidation, mitochondrial dysfunction, excessive reactive oxygen species (ros) production, and inflammation, all related to further steatosis progression and fibrosis. |
2022-11-12 |
2023-08-14 |
Not clear |
| Hager H Shaaban, Ibrahim Alzaim, Ahmed El-Mallah, Rania G Aly, Ahmed F El-Yazbi, Ahmed Wahi. Metformin, pioglitazone, dapagliflozin and their combinations ameliorate manifestations associated with NAFLD in rats via anti-inflammatory, anti-fibrotic, anti-oxidant and anti-apoptotic mechanisms. Life sciences. 2022-09-14. PMID:36103959. |
rats were fed an atherogenic diet containing 1.25 % cholesterol, 0.5 % cholic acid and 60 % cocoa butter for 6 weeks causing a number of metabolic and hepatic alterations including insulin resistance, dyslipidemia, systemic inflammation, increased hepatic oxidative stress and lipid peroxidation, hepatic steatosis, lobular inflammation, as well as increased markers of liver inflammation and hepatocyte apoptosis. |
2022-09-14 |
2023-08-14 |
rat |
| Li Chen, Rui Xu, Joshua D McDonald, Richard S Bruno, Fouad Choueiry, Jiangjiang Zh. Dairy Milk Casein and Whey Proteins Differentially Alter the Postprandial Lipidome in Persons with Prediabetes: A Comparative Lipidomics Study. Journal of agricultural and food chemistry. 2022-08-10. PMID:35948437. |
meanwhile, the decreased acyl carnitines and fatty acid (fa) 16:0 levels could attenuate lipid peroxidation after protein intervention to protect insulin secretory capacity. |
2022-08-10 |
2023-08-14 |
human |