| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P T Biessels, G A Berbers, G C Broeders, R Landsvater, H G Huisman, W K Bleeker, J C Bakke. Detection of erythrocyte membrane components in hemoglobin-based blood substitutes. Clinica chimica acta; international journal of clinical chemistry. vol 212. issue 3. 1993-02-05. PMID:1477974. |
hb solutions prepared by filtration of red blood cells, gradually swollen in hypotonic buffer, contained 0.25% of the original amount of phospholipid and no detectable glycophorin alpha. |
1993-02-05 |
2023-08-11 |
human |
| P T Biessels, G A Berbers, G C Broeders, R Landsvater, H G Huisman, W K Bleeker, J C Bakke. Detection of erythrocyte membrane components in hemoglobin-based blood substitutes. Clinica chimica acta; international journal of clinical chemistry. vol 212. issue 3. 1993-02-05. PMID:1477974. |
for hb solutions prepared in a similar way from red blood cells lysed in water, the values for phospholipid and glycophorin alpha were 2.5% and 0.06%, respectively. |
1993-02-05 |
2023-08-11 |
human |
| P T Biessels, G A Berbers, G C Broeders, R Landsvater, H G Huisman, W K Bleeker, J C Bakke. Detection of erythrocyte membrane components in hemoglobin-based blood substitutes. Clinica chimica acta; international journal of clinical chemistry. vol 212. issue 3. 1993-02-05. PMID:1477974. |
the determination of both glycophorin alpha and phospholipid gives a useful indication of the purity of hb solutions. |
1993-02-05 |
2023-08-11 |
human |
| M D Gross, S M Gapstur, J D Belcher, G Scanlan, J D Potte. The identification and partial characterization of acetaldehyde adducts of hemoglobin occurring in vivo: a possible marker of alcohol consumption. Alcoholism, clinical and experimental research. vol 16. issue 6. 1993-01-27. PMID:1471764. |
a comparison of the observed mass for the peptides with the theoretical masses for acetaldehyde-modified hb peptides suggested that the peptides were ach-modified alpha and beta chain n-termini of hb. |
1993-01-27 |
2023-08-11 |
Not clear |
| Y J Fei, R Oner, G Bözkurt, L H Gu, C Altay, A Gurgey, S Fattoum, E Baysal, T H Huisma. Hb H disease caused by a homozygosity for the AATAAA-->AATAAG mutation in the polyadenylation site of the alpha 2-globin gene: hematological observations. Acta haematologica. vol 88. issue 2-3. 1993-01-21. PMID:1281602. |
hb h disease caused by a homozygosity for the aataaa-->aataag mutation in the polyadenylation site of the alpha 2-globin gene: hematological observations. |
1993-01-21 |
2023-08-11 |
Not clear |
| V Divoky, E Bissé, J B Wilson, L H Gu, H Wieland, I Heinrichs, J F Prior, T H Huisma. Heterozygosity for the IVS-I-5 (G-->C) mutation with a G-->A change at codon 18 (Val-->Met; Hb Baden) in cis and a T-->G mutation at codon 126 (Val-->Gly; Hb Dhonburi) in trans resulting in a thalassemia intermedia. Biochimica et biophysica acta. vol 1180. issue 2. 1993-01-21. PMID:1463768. |
one chromosome of the propositus and one of his father's carried the gtg-->ggg mutation at codon 126 leading to the synthesis of hb dhonburi or alpha 2 beta (2)126(h4)val-->gly; this variant is slightly unstable and is associated with mild thalassemic features. |
1993-01-21 |
2023-08-11 |
Not clear |
| M E Fabry, R L Nagel, A Pachnis, S M Suzuka, F Costantin. High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 24. 1993-01-19. PMID:1465454. |
because mouse alpha chains inhibit hemoglobin (hb) s polymerization, we bred the mice to heterozygosity for a mouse alpha-globin deletion. |
1993-01-19 |
2023-08-11 |
mouse |
| M E Fabry, R L Nagel, A Pachnis, S M Suzuka, F Costantin. High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 24. 1993-01-19. PMID:1465454. |
transgenic alpha h beta s[beta mdd] mice had normal hematocrit and hb and somewhat elevated reticulocytes (6% vs. 3% for control), whereas the mice carrying the alpha-globin deletion (alpha h beta s[alpha md beta mdd]) had a normal hematocrit and hb and more elevated reticulocytes (10.3 +/- 7.6% vs. 3.4 +/- 1.0%). |
1993-01-19 |
2023-08-11 |
mouse |
| M E Fabry, R L Nagel, A Pachnis, S M Suzuka, F Costantin. High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 24. 1993-01-19. PMID:1465454. |
expression of the transgene restored a normal distribution of erythrocyte densities when compared to thalassemic mice; however, the average mean corpuscular hb concentration of alpha h beta s[beta mdd] mice increased to 35.7 g/dl (vs. control 33.7 g/dl) whereas that of alpha h beta s[alpha md beta mdd] mice was further elevated to 36.3 g/dl. |
1993-01-19 |
2023-08-11 |
mouse |
| M E Fabry, R L Nagel, A Pachnis, S M Suzuka, F Costantin. High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 24. 1993-01-19. PMID:1465454. |
the higher values of the mean corpuscular hb concentration and intrinsic po2 at midsaturation, which favor in vivo sickling, may explain the slightly more severe hematological picture in alpha h beta s[alpha md beta mdd] mice. |
1993-01-19 |
2023-08-11 |
mouse |
| T P Molchanova, J B Wilson, L H Gu, R D Hain, L S Chang, A O Poon, T H Huisma. A second observation of the fetal methemoglobin variant Hb F-M-Fort Ripley or alpha 2G gamma 2(92)(F8)His----Tyr. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1385361. |
a second observation of the fetal methemoglobin variant hb f-m-fort ripley or alpha 2g gamma 2(92)(f8)his----tyr. |
1992-12-14 |
2023-08-11 |
Not clear |
| S Abbes, A M'Rad, P A Fitzgerald, P Dormer, Y Blouquit, J Kister, F Galacteros, H Wajcma. HB Al-Ain Abu Dhabi [alpha 18(A16)Gly----Asp]: a new hemoglobin variant discovered in an Emiratee family. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428941. |
hb al-ain abu dhabi [alpha 18(a16)gly----asp]: a new hemoglobin variant discovered in an emiratee family. |
1992-12-14 |
2023-08-11 |
Not clear |
| S Abbes, A M'Rad, P A Fitzgerald, P Dormer, Y Blouquit, J Kister, F Galacteros, H Wajcma. HB Al-Ain Abu Dhabi [alpha 18(A16)Gly----Asp]: a new hemoglobin variant discovered in an Emiratee family. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428941. |
the structural determination, performed by reversed phase high performance liquid chromatography and amino acid sequencing, revealed a new variant that we named hb al-ain abu dhabi [alpha 18(a16) gly----asp]. |
1992-12-14 |
2023-08-11 |
Not clear |
| T C Liu, J S Yen, J S Shen, Y H Chen, L S Lee, P H Chen, J G Chan. Rapid molecular diagnosis of hemoglobin variants by RT-PCR of reticulocyte mRNA and direct sequencing. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428942. |
the amino acid substitution of hb g-taichung is due to a g----c mutation at codon 74 of the alpha 1-globin gene, that of hb j-meinung to a g----a substitution at codon 56 of the beta-globin gene, and that of hb kaohsiung (or new york) to a t----a substitution at codon 113 of the beta-globin gene. |
1992-12-14 |
2023-08-11 |
Not clear |
| C W Su, S Liang, R Liang, X J Wen, C N Tan. Hb H disease in association with the silent beta chain variant Hb Hamilton or alpha 2 beta 2(11)(A8)Val----Ile. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428944. |
hb h disease in association with the silent beta chain variant hb hamilton or alpha 2 beta 2(11)(a8)val----ile. |
1992-12-14 |
2023-08-11 |
Not clear |
| M A Cürük, A Kutlar, T H Huisma. Hb Shelby [alpha 2 beta 2(131)(H9)Gln----Lys]-beta zero-thalassemia [codon 15 (TGG----TGA)] identified by DNA sequencing. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428946. |
hb shelby [alpha 2 beta 2(131)(h9)gln----lys]-beta zero-thalassemia [codon 15 (tgg----tga)] identified by dna sequencing. |
1992-12-14 |
2023-08-11 |
Not clear |
| K Fujisawa, Y Hattori, Y Ohba, S And. Hb Yuda or alpha 130(H13)Ala----Asp; a new alpha chain variant with low oxygen affinity. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428950. |
hb yuda or alpha 130(h13)ala----asp; a new alpha chain variant with low oxygen affinity. |
1992-12-14 |
2023-08-11 |
Not clear |
| B B Webber, J B Wilson, L H Gu, T H Huisma. Hb Ethiopia or alpha 2(140)(HC2)Tyr----His beta 2. Hemoglobin. vol 16. issue 5. 1992-12-14. PMID:1428951. |
hb ethiopia or alpha 2(140)(hc2)tyr----his beta 2. |
1992-12-14 |
2023-08-11 |
Not clear |
| S G Condò, M Corda, M T Sanna, M G Pellegrini, M P Ruiz, M Castagnola, B Giardin. Molecular basis of low-temperature sensitivity in pig hemoglobins. European journal of biochemistry. vol 209. issue 2. 1992-12-03. PMID:1425681. |
here we report a detailed functional characterization of pig hb, which, interpreted on the basis of the amino acid sequence of the alpha and beta chains of the molecule, sheds some light on the molecular basis of the phenomenon. |
1992-12-03 |
2023-08-11 |
human |
| H Wajcman, J Kister, M Marden, A Lahary, M Monconduit, F Galactero. Hemoglobin Rouen (alpha-140 (HC2) Tyr-->His): alteration of the alpha-chain C-terminal region and moderate increase in oxygen affinity. Biochimica et biophysica acta. vol 1180. issue 1. 1992-11-19. PMID:1390944. |
hb rouen (alpha 140(hc2) tyr-->his) is a moderately high oxygen-affinity variant that was found in coincidence with polycythemia vera in a french patient. |
1992-11-19 |
2023-08-11 |
Not clear |