| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caio E G Reis, Cicília L R Dos S Paiva, Angélica A Amato, Adriana Lofrano-Porto, Sara Wassell, Leslie J C Bluck, José G Dórea, Teresa H M da Cost. Decaffeinated coffee improves insulin sensitivity in healthy men. The British journal of nutrition. vol 119. issue 9. 2019-04-03. PMID:29514721. |
glucose, insulin, c-peptide, glp-1 and gip levels were not statistically different after regular and decaffeinated coffee compared with water. |
2019-04-03 |
2023-08-13 |
human |
| Bayissa Hatew, Yudai Inabu, Toshihisa Sugino, Michael Steel. Effects of pulse-dose ruminal infusion of butyrate on plasma glucagon-like peptide 1 and 2 concentrations in dairy calves. Journal of dairy science. vol 102. issue 3. 2019-03-29. PMID:30660418. |
ruminal and plasma butyrate, β-hydroxybutyrate, glp-1, glp-2, insulin, and glucose concentrations were all affected by treatment, time (except glp-2), and interaction of treatment with time (except glp-1). |
2019-03-29 |
2023-08-13 |
Not clear |
| Aurore Quinault, Blandine Gausseres, Danielle Bailbe, Nella Chebbah, Bernard Portha, Jamileh Movassat, Cecile Tourrel-Cuzi. Disrupted dynamics of F-actin and insulin granule fusion in INS-1 832/13 beta-cells exposed to glucotoxicity: partial restoration by glucagon-like peptide 1. Biochimica et biophysica acta. vol 1862. issue 8. 2019-03-28. PMID:27101990. |
the most interesting in our results is the partial restoration by glp-1 of the insulin secretion ability from high-glucose treated ins-1 832/13 cells. |
2019-03-28 |
2023-08-13 |
Not clear |
| Jia Ying Cheang, Peter M Moyl. Glucagon-Like Peptide-1 (GLP-1)-Based Therapeutics: Current Status and Future Opportunities beyond Type 2 Diabetes. ChemMedChem. vol 13. issue 7. 2019-03-18. PMID:29430842. |
glucagon-like peptide-1 (glp-1) is secreted by intestinal l-cells following food intake, and plays an important role in glucose homeostasis due to its stimulation of glucose-dependent insulin secretion. |
2019-03-18 |
2023-08-13 |
Not clear |
| J Malik, N Rooh. GLP-1, a powerful physiological incretin: an update. Journal of biological regulators and homeostatic agents. vol 32. issue 5. 2019-03-15. PMID:30334409. |
among the various endocrine modulators, glucagon-like peptide 1 (glp-1) is more effective in stimulating the release of insulin and more powerful regulator of physiological functions. |
2019-03-15 |
2023-08-13 |
human |
| T Dung Nguyen, Yasushige Shingu, Paulo A Amorim, Christina Schenkl, Michael Schwarzer, Torsten Doens. GLP-1 Improves Diastolic Function and Survival in Heart Failure with Preserved Ejection Fraction. Journal of cardiovascular translational research. vol 11. issue 3. 2019-03-14. PMID:29464655. |
while glp-1 may boost insulin secretion and responsiveness, the protective effects were not related to cardiac insulin action. |
2019-03-14 |
2023-08-13 |
rat |
| A J Scheen, N Paquo. [Management of hyperglycaemia of type 2 diabetes. Paradigm change according to the ADA-EASD consensus report 2018]. Revue medicale de Liege. vol 73. issue 12. 2019-03-12. PMID:30570234. |
if oral treatment is insufficient, the preference is now given to a glp-1 receptor agonist rather than basal insulin. |
2019-03-12 |
2023-08-13 |
Not clear |
| Agnese Filippello, Francesca Urbano, Stefania Di Mauro, Alessandra Scamporrino, Antonino Di Pino, Roberto Scicali, Agata Maria Rabuazzo, Francesco Purrello, Salvatore Pir. Chronic Exposure to Palmitate Impairs Insulin Signaling in an Intestinal L-cell Line: A Possible Shift from GLP-1 to Glucagon Production. International journal of molecular sciences. vol 19. issue 12. 2019-03-11. PMID:30487448. |
chronic exposure to palmitate impairs insulin signaling in an intestinal l-cell line: a possible shift from glp-1 to glucagon production. |
2019-03-11 |
2023-08-13 |
Not clear |
| Agnese Filippello, Francesca Urbano, Stefania Di Mauro, Alessandra Scamporrino, Antonino Di Pino, Roberto Scicali, Agata Maria Rabuazzo, Francesco Purrello, Salvatore Pir. Chronic Exposure to Palmitate Impairs Insulin Signaling in an Intestinal L-cell Line: A Possible Shift from GLP-1 to Glucagon Production. International journal of molecular sciences. vol 19. issue 12. 2019-03-11. PMID:30487448. |
obesity and type 2 diabetes mellitus (t2dm) are characterized by insulin resistance and impaired glucagon-like peptide-1 (glp-1) secretion/function. |
2019-03-11 |
2023-08-13 |
Not clear |
| Agnese Filippello, Francesca Urbano, Stefania Di Mauro, Alessandra Scamporrino, Antonino Di Pino, Roberto Scicali, Agata Maria Rabuazzo, Francesco Purrello, Salvatore Pir. Chronic Exposure to Palmitate Impairs Insulin Signaling in an Intestinal L-cell Line: A Possible Shift from GLP-1 to Glucagon Production. International journal of molecular sciences. vol 19. issue 12. 2019-03-11. PMID:30487448. |
the aim of this study was to investigate the effects of chronic palmitate exposure on insulin pathways, glp-1 secretion and glucagon synthesis in the glutag l-cell line. |
2019-03-11 |
2023-08-13 |
Not clear |
| Noppadol Kietsiriroje, Krisana Kanjanahirun, Jirateep Kwankaew, Ratikorn Ponrak, Supamai Soonthornpu. Phytosterols and inulin-enriched soymilk increases glucagon-like peptide-1 secretion in healthy men: double-blind randomized controlled trial, subgroup study. BMC research notes. vol 11. issue 1. 2019-03-08. PMID:30497507. |
the study aimed to determine the effect of phytosterols and inulin on plasma glucose, insulin, and glp-1 levels among healthy men after consuming phytosterols and inulin-enriched soymilk for 8 weeks. |
2019-03-08 |
2023-08-13 |
Not clear |
| Preeti Pathak, Cen Xie, Robert G Nichols, Jessica M Ferrell, Shannon Boehme, Kristopher W Krausz, Andrew D Patterson, Frank J Gonzalez, John Y L Chian. Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism. Hepatology (Baltimore, Md.). vol 68. issue 4. 2019-03-07. PMID:29486523. |
we reported recently that activation of fxr induces tgr5 to stimulate glucagon-like peptide-1 (glp-1) secretion to improve insulin sensitivity and hepatic metabolism. |
2019-03-07 |
2023-08-13 |
mouse |
| Preeti Pathak, Cen Xie, Robert G Nichols, Jessica M Ferrell, Shannon Boehme, Kristopher W Krausz, Andrew D Patterson, Frank J Gonzalez, John Y L Chian. Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism. Hepatology (Baltimore, Md.). vol 68. issue 4. 2019-03-07. PMID:29486523. |
the current study revealed that fex markedly increased taurolithocholic acid, increased secretion of fibroblast growth factors 15 and 21 and glp-1, improved insulin and glucose tolerance, and promoted white adipose tissue browning in mice. |
2019-03-07 |
2023-08-13 |
mouse |
| Preeti Pathak, Cen Xie, Robert G Nichols, Jessica M Ferrell, Shannon Boehme, Kristopher W Krausz, Andrew D Patterson, Frank J Gonzalez, John Y L Chian. Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism. Hepatology (Baltimore, Md.). vol 68. issue 4. 2019-03-07. PMID:29486523. |
fex treatment effectively improved lipid profiles, increased glp-1 secretion, improved glucose and insulin tolerance, and promoted adipose tissue browning, while antibiotic treatment reversed the beneficial metabolic effects of fex in obese and diabetic mice. |
2019-03-07 |
2023-08-13 |
mouse |
| Y Inabu, A Fischer, Y Song, L L Guan, M Oba, M A Steele, T Sugin. Short communication: The effect of delayed colostrum feeding on plasma concentrations of glucagon-like peptide 1 and 2 in newborn calves. Journal of dairy science. vol 101. issue 7. 2019-02-27. PMID:29680641. |
blood samples were obtained before the colostrum feeding and every 3 h after each colostrum feeding for a 36-h period, and plasma concentrations of glp-1, glp-2, insulin, and glucose were measured. |
2019-02-27 |
2023-08-13 |
Not clear |
| Y Inabu, A Fischer, Y Song, L L Guan, M Oba, M A Steele, T Sugin. Short communication: The effect of delayed colostrum feeding on plasma concentrations of glucagon-like peptide 1 and 2 in newborn calves. Journal of dairy science. vol 101. issue 7. 2019-02-27. PMID:29680641. |
these results indicate that delayed colostrum feeding can decrease plasma glp-1 and insulin concentrations without affecting glucose or glp-2 concentration. |
2019-02-27 |
2023-08-13 |
Not clear |
| Emanuel Candeias, Inês Sebastião, Susana Cardoso, Cristina Carvalho, Maria Sancha Santos, Catarina Resende Oliveira, Paula I Moreira, Ana I Duart. Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats. Molecular neurobiology. vol 55. issue 5. 2019-02-26. PMID:28573460. |
glp-1, insulin, and igf-1, their downstream signaling and autophagic markers were evaluated by specific elisa kits and western blotting. |
2019-02-26 |
2023-08-13 |
rat |
| Michael G Spelios, Lauren A Afinowicz, Regine C Tipon, Eitan M Akira. Human EndoC-βH1 β-cells form pseudoislets with improved glucose sensitivity and enhanced GLP-1 signaling in the presence of islet-derived endothelial cells. American journal of physiology. Endocrinology and metabolism. vol 314. issue 5. 2019-02-21. PMID:29351476. |
iec-induced pis demonstrated reduced dysregulated insulin release under low glucose levels and higher insulin secretion in response to high glucose and exendin-4 [a glucagon-like peptide-1 (glp-1) analog] compared with monolayer cells cultured alone. |
2019-02-21 |
2023-08-13 |
human |
| Michael G Spelios, Lauren A Afinowicz, Regine C Tipon, Eitan M Akira. Human EndoC-βH1 β-cells form pseudoislets with improved glucose sensitivity and enhanced GLP-1 signaling in the presence of islet-derived endothelial cells. American journal of physiology. Endocrinology and metabolism. vol 314. issue 5. 2019-02-21. PMID:29351476. |
this rapid coculture system provides an unlimited number of human pis with improved insulin secretion and glp-1 responsiveness for the study of β-cell biology. |
2019-02-21 |
2023-08-13 |
human |
| Hisae Ando, Koro Gotoh, Kansuke Fujiwara, Manabu Anai, Seiichi Chiba, Takayuki Masaki, Tetsuya Kakuma, Hirotaka Shibat. Glucagon-like peptide-1 reduces pancreatic β-cell mass through hypothalamic neural pathways in high-fat diet-induced obese rats. Scientific reports. vol 7. issue 1. 2019-02-20. PMID:28717164. |
chronic glp-1 (7-36) administration to hfd-induced obese rats elevated c-fos expression and bdnf content in the hypothalamus, followed by a reduction in pancreatic β-cell hyperplasia and insulin content, thus resulting in improved glucose tolerance. |
2019-02-20 |
2023-08-13 |
rat |