| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Florian Ehehalt, Klaus Knoch, Katja Erdmann, Christian Krautz, Melanie Jäger, Anja Steffen, Carolin Wegbrod, Ronny Meisterfeld, Stephan Kersting, Hendrik Bergert, E Kuhlisch, Stefan Bornstein, Ezio Bonifacio, Hans-Detlev Saeger, Michele Solimen. Impaired insulin turnover in islets from type 2 diabetic patients. Islets. vol 2. issue 1. 2011-03-31. PMID:21099291. |
in parallel, we also investigated the subcellular localization of polypyrimidine tract-binding protein 1 (ptbp1), whose nucleocytoplasmic translocation is involved in the rapid posttranscriptional up-regulation of insulin biosynthesis following islet stimulation with glucose and glp-1. |
2011-03-31 |
2023-08-12 |
human |
| Martins Kalis, Rajesh Kumar, Sabina Janciauskiene, Albert Salehi, Corrado M Cili. α 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells. Islets. vol 2. issue 3. 2011-03-31. PMID:21099312. |
ins-1e cells or primary rat pancreatic islets were used to study the effect of aat on insulin secretion after glucose, glucagon-like peptide-1 (glp-1) and forskolin stimulation and on cytokine-mediated apoptosis. |
2011-03-31 |
2023-08-12 |
rat |
| Martins Kalis, Rajesh Kumar, Sabina Janciauskiene, Albert Salehi, Corrado M Cili. α 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells. Islets. vol 2. issue 3. 2011-03-31. PMID:21099312. |
we found that aat increases insulin secretion in a glucose-dependent manner, potentiates the effect of glp-1 and forskolin and neutralizes the inhibitory effect of clonidine on insulin secretion. |
2011-03-31 |
2023-08-12 |
rat |
| D C Lubbs, B M Vester Boler, T K Ridge, J K Spears, T K Graves, K S Swanso. Dietary macronutrients and feeding frequency affect fasting and postprandial concentrations of hormones involved in appetite regulation in adult dogs. Journal of animal science. vol 88. issue 12. 2011-03-28. PMID:20729279. |
total ghrelin, active glucagon-like peptide-1 (glp-1), insulin, and glucose concentrations were measured. |
2011-03-28 |
2023-08-12 |
chicken |
| D C Lubbs, B M Vester Boler, T K Ridge, J K Spears, T K Graves, K S Swanso. Dietary macronutrients and feeding frequency affect fasting and postprandial concentrations of hormones involved in appetite regulation in adult dogs. Journal of animal science. vol 88. issue 12. 2011-03-28. PMID:20729279. |
1, all hormones were quite variable throughout the day, with a few insulin and glp-1 differences because of feeding frequency. |
2011-03-28 |
2023-08-12 |
chicken |
| D C Lubbs, B M Vester Boler, T K Ridge, J K Spears, T K Graves, K S Swanso. Dietary macronutrients and feeding frequency affect fasting and postprandial concentrations of hormones involved in appetite regulation in adult dogs. Journal of animal science. vol 88. issue 12. 2011-03-28. PMID:20729279. |
the circulating hormone data were highly variable and indicate that diet plays a role in insulin and glp-1 secretion, but more research is required to elucidate these effects. |
2011-03-28 |
2023-08-12 |
chicken |
| Roy Eldor, Miriam Kidron, Yael Greenberg-Shushlav, Ehud Arbi. Novel glucagon-like peptide-1 analog delivered orally reduces postprandial glucose excursions in porcine and canine models. Journal of diabetes science and technology. vol 4. issue 6. 2011-03-25. PMID:21129350. |
glucagon-like peptide-1 (glp-1) and its analogs are associated with a gamut of physiological processes, including induction of insulin release, support of normoglycemia, β-cell function preservation, improved lipid profiles, and increased insulin sensitivity. |
2011-03-25 |
2023-08-12 |
Not clear |
| R Burcelin, S Dejage. GLP-1: what is known, new and controversial in 2010? Diabetes & metabolism. vol 36. issue 6 Pt 1. 2011-03-23. PMID:21075654. |
glp-1 analogues would certainly be helpful in association with long-acting insulin (albeit off-label) in patients with impaired beta cells and glp-1 secretory potential. |
2011-03-23 |
2023-08-12 |
Not clear |
| Michael A Nauc. Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications. The American journal of medicine. vol 124. issue 1 Suppl. 2011-03-22. PMID:21194578. |
the incretin hormones, glucose-dependent insulinotropic polypeptide (gip) and glucagonlike peptide-1 (glp-1), which are secreted by cells of the gastrointestinal tract in response to meal ingestion, exercise important glucoregulatory effects, including the glucose-dependent potentiation of insulin secretion by pancreatic β-cells. |
2011-03-22 |
2023-08-12 |
Not clear |
| Katrine B Hansen, Tina Vilsbøll, Jonatan I Bagger, Jens J Holst, Filip K Kno. Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects. The Journal of clinical endocrinology and metabolism. vol 96. issue 2. 2011-03-21. PMID:21047927. |
we aimed to determine the impact of insulin resistance and reduced glucose tolerance on postprandial gip, glp-1, and glucagon responses in healthy subjects. |
2011-03-21 |
2023-08-12 |
human |
| M T Marino, J P Cassidy, R A Baughman, A H Boss, P C Richardso. A new C-Peptide correction model used to assess bioavailability of regular human insulin. Biopharmaceutics & drug disposition. vol 31. issue 7. 2011-03-03. PMID:20812342. |
these studies used hyper-insulinemic euglycemic clamps or meal challenges and subjects received insulin or glucagon-like peptide 1 (glp-1). |
2011-03-03 |
2023-08-12 |
human |
| Virginia Boccardi, Immacolata Ambrosino, Michela Papa, Daniela Fiore, Maria Rosaria Rizzo, Giuseppe Paolisso, Michelangela Barbier. Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity. European journal of human genetics : EJHG. vol 18. issue 12. 2011-02-28. PMID:20648057. |
we aimed to evaluate the potential role of tcf7l2 gene polymorphisms on sympathovagal response in relation to changes in plasma insulin and/or glp-1 concentration after glucose ingestion. |
2011-02-28 |
2023-08-12 |
human |
| Virginia Boccardi, Immacolata Ambrosino, Michela Papa, Daniela Fiore, Maria Rosaria Rizzo, Giuseppe Paolisso, Michelangela Barbier. Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity. European journal of human genetics : EJHG. vol 18. issue 12. 2011-02-28. PMID:20648057. |
at baseline, no differences in fasting plasma insulin, in glp-1 levels and in lf/hf (low frequency/high frequency) ratio between the three genotypes were found. |
2011-02-28 |
2023-08-12 |
human |
| Virginia Boccardi, Immacolata Ambrosino, Michela Papa, Daniela Fiore, Maria Rosaria Rizzo, Giuseppe Paolisso, Michelangela Barbier. Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity. European journal of human genetics : EJHG. vol 18. issue 12. 2011-02-28. PMID:20648057. |
moreover, such effect is independent of glp-1 and insulin plasma concentrations suggesting a potential role of such gene variants in increasing cardiovascular risk through enhanced sympathetic nervous system activity. |
2011-02-28 |
2023-08-12 |
human |
| Grace Flock, Dianne Holland, Yutaka Seino, Daniel J Drucke. GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms. Endocrinology. vol 152. issue 2. 2011-02-25. PMID:21068156. |
experimental endpoints included plasma glucose, insulin, glucagon, glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic peptide (gip), and peptide yy. |
2011-02-25 |
2023-08-12 |
mouse |
| Grace Flock, Dianne Holland, Yutaka Seino, Daniel J Drucke. GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms. Endocrinology. vol 152. issue 2. 2011-02-25. PMID:21068156. |
ar231453 stimulated insulin secretion from wt and dirko islets in a glucose-dependent manner, improved glucose homeostasis, and augmented plasma levels of glp-1, gip, and insulin in wt and gipr-/- mice. |
2011-02-25 |
2023-08-12 |
mouse |
| Grace Flock, Dianne Holland, Yutaka Seino, Daniel J Drucke. GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms. Endocrinology. vol 152. issue 2. 2011-02-25. PMID:21068156. |
in contrast, although ar231453 increased levels of glp-1, gip, and insulin, it failed to lower glucose in glp1r-/- and dirko mice. |
2011-02-25 |
2023-08-12 |
mouse |
| T Edholm, M Degerblad, P Grybäck, L Hilsted, J J Holst, H Jacobsson, S Efendic, P T Schmidt, P M Hellströ. Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 22. issue 11. 2011-02-08. PMID:20584260. |
the aim of this study was to investigate effects of gip and glp-1 on gastric emptying and appetite after a mixed meal, and effects on insulin secretion and glucose disposal in humans. |
2011-02-08 |
2023-08-12 |
Not clear |
| Mathias Nicolaus, Julia Brödl, Rainer Linke, Hans-Juergen Woerle, Burkhard Göke, Jörg Schirr. Endogenous GLP-1 regulates postprandial glycemia in humans: relative contributions of insulin, glucagon, and gastric emptying. The Journal of clinical endocrinology and metabolism. vol 96. issue 1. 2011-02-04. PMID:21047924. |
endogenous glp-1 regulates postprandial glycemia in humans: relative contributions of insulin, glucagon, and gastric emptying. |
2011-02-04 |
2023-08-12 |
Not clear |
| Mathias Nicolaus, Julia Brödl, Rainer Linke, Hans-Juergen Woerle, Burkhard Göke, Jörg Schirr. Endogenous GLP-1 regulates postprandial glycemia in humans: relative contributions of insulin, glucagon, and gastric emptying. The Journal of clinical endocrinology and metabolism. vol 96. issue 1. 2011-02-04. PMID:21047924. |
synthetic glucagon-like peptide-1 (7-36)amide (glp-1) lowers postprandial (pp) glycemia by stimulating insulin and inhibiting glucagon release and delaying gastric emptying (ge). |
2011-02-04 |
2023-08-12 |
Not clear |