| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niina Matikainen, Leonie H Bogl, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Jaakko Kaprio, Aila Rissanen, Jens J Holst, Kirsi H Pietiläine. GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance. Diabetes care. vol 37. issue 1. 2015-04-22. PMID:23990519. |
in contrast, higher insulin responses and blunted 60-min glp-1 responses during the ogtt were observed in the heavier as compared with leaner mz cotwins discordant for bmi, liver fat, and insulin sensitivity. |
2015-04-22 |
2023-08-12 |
Not clear |
| Niina Matikainen, Leonie H Bogl, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Jaakko Kaprio, Aila Rissanen, Jens J Holst, Kirsi H Pietiläine. GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance. Diabetes care. vol 37. issue 1. 2015-04-22. PMID:23990519. |
blunted glp-1 response to ogtt was observed in heavier as compared with leaner dz cotwins discordant for obesity and insulin sensitivity. |
2015-04-22 |
2023-08-12 |
Not clear |
| Niina Matikainen, Leonie H Bogl, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Jaakko Kaprio, Aila Rissanen, Jens J Holst, Kirsi H Pietiläine. GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance. Diabetes care. vol 37. issue 1. 2015-04-22. PMID:23990519. |
conclusions whereas the glp-1 response to the ogtt is heritable, an acquired unhealthy pattern of obesity characterized by liver fat accumulation and insulin resistance is closely related to impaired glp-1 response in young adults. |
2015-04-22 |
2023-08-12 |
Not clear |
| Jacqueline A Koehler, Laurie L Baggio, Xiemin Cao, Tahmid Abdulla, Jonathan E Campbell, Thomas Secher, Jacob Jelsing, Brett Larsen, Daniel J Drucke. Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis. Diabetes. vol 64. issue 3. 2015-04-22. PMID:25277394. |
glucagon-like peptide-1 (glp-1) controls glucose homeostasis by regulating secretion of insulin and glucagon through a single glp-1 receptor (glp-1r). |
2015-04-22 |
2023-08-13 |
mouse |
| Lucy S Jun, Rohn L Millican, Eric D Hawkins, Debra L Konkol, Aaron D Showalter, Michael E Christe, M Dodson Michael, Kyle W Sloo. Absence of glucagon and insulin action reveals a role for the GLP-1 receptor in endogenous glucose production. Diabetes. vol 64. issue 3. 2015-04-22. PMID:25288673. |
absence of glucagon and insulin action reveals a role for the glp-1 receptor in endogenous glucose production. |
2015-04-22 |
2023-08-13 |
mouse |
| Annette Plesner, Joris T Ten Holder, C Bruce Vercher. Islet remodeling in female mice with spontaneous autoimmune and streptozotocin-induced diabetes. PloS one. vol 9. issue 8. 2015-04-21. PMID:25101835. |
serum levels of insulin, glucagon and glp-1 were measured to compare hormone levels with respect to disease state. |
2015-04-21 |
2023-08-13 |
mouse |
| Natalia Petersen, Frank Reimann, Johan H van Es, Bernard M van den Berg, Chantal Kroone, Ramona Pais, Erik Jansen, Hans Clevers, Fiona M Gribble, Eelco J P de Konin. Targeting development of incretin-producing cells increases insulin secretion. The Journal of clinical investigation. vol 125. issue 1. 2015-04-21. PMID:25500886. |
while these agents augment insulin secretion, they do not mimic the physiological meal-related rise and fall of glp-1 concentrations. |
2015-04-21 |
2023-08-13 |
mouse |
| Natalia Petersen, Frank Reimann, Johan H van Es, Bernard M van den Berg, Chantal Kroone, Ramona Pais, Erik Jansen, Hans Clevers, Fiona M Gribble, Eelco J P de Konin. Targeting development of incretin-producing cells increases insulin secretion. The Journal of clinical investigation. vol 125. issue 1. 2015-04-21. PMID:25500886. |
here, we tested the hypothesis that increasing the number of intestinal l cells, which produce glp-1, is an alternative strategy to augment insulin responses and improve glucose tolerance. |
2015-04-21 |
2023-08-13 |
mouse |
| Andrew S Rhinehar. Adding GLP-1 Receptor Agonist Therapy to Basal Insulin for Postprandial Glucose Control. Clinical diabetes : a publication of the American Diabetes Association. vol 33. issue 2. 2015-04-21. PMID:25897187. |
adding glp-1 receptor agonist therapy to basal insulin for postprandial glucose control. |
2015-04-21 |
2023-08-13 |
Not clear |
| Okan Bakiner, Emre Bozkirli, Semih Giray, Zulfikar Arlier, Ilknur Kozanoglu, Nurzen Sezgin, Cagla Sariturk, Eda Ertore. Impact of early versus late enteral nutrition on cell mediated immunity and its relationship with glucagon like peptide-1 in intensive care unit patients: a prospective study. Critical care (London, England). vol 17. issue 3. 2015-04-20. PMID:23786864. |
glucagon-like peptide-1 (glp-1) originates from the gastrointestinal system in response to the presence of nutrition in the intestinal lumen and potentiates postprandial insulin secretion. |
2015-04-20 |
2023-08-12 |
Not clear |
| Takafumi Watanabe, Kei Nishimura, Yoshinao Z Hosaka, Takeshi Shimosato, Shinichi Yonekura, Daisuke Suzuki, Chihiro Takemoto, Mohammad Moniruzzaman Monir, Kohzy Hiramats. Histological analysis of glucagon-like peptide-1 receptor expression in chicken pancreas. Cell and tissue research. vol 357. issue 1. 2015-04-17. PMID:24797838. |
the main biological effect of glp-1 is the stimulation of insulin secretion (thereby fulfilling the criterion for an incretin hormone) in order to reduce blood glucose levels in mammalian species. |
2015-04-17 |
2023-08-13 |
chicken |
| John Wildin. Managing patients with type 2 diabetes and obesity. The Practitioner. vol 259. issue 1778. 2015-04-17. PMID:25726618. |
adjunctive treatment with metformin, sglt2 inhibitors, dpp-iv inhibitors and glp-1 analogues can help keep insulin doses lower and limit weight gain. |
2015-04-17 |
2023-08-13 |
Not clear |
| Caroline Montelius, Daniel Erlandsson, Egzona Vitija, Eva-Lena Stenblom, Emil Egecioglu, Charlotte Erlanson-Albertsso. Body weight loss, reduced urge for palatable food and increased release of GLP-1 through daily supplementation with green-plant membranes for three months in overweight women. Appetite. vol 81. 2015-04-14. PMID:24993695. |
on days 1 and 90, following intake of a standardized breakfast, glucose, insulin and glucagon-like peptide 1 (glp-1) in plasma were measured, as well as subjective ratings of hunger, satiety and urge for different palatable foods, using visual analogue scales. |
2015-04-14 |
2023-08-13 |
human |
| Wathik Alsalim, Bilal Omar, Giovanni Pacini, Roberto Bizzotto, Andrea Mari, Bo Ahré. Incretin and islet hormone responses to meals of increasing size in healthy subjects. The Journal of clinical endocrinology and metabolism. vol 100. issue 2. 2015-04-14. PMID:25375983. |
postprandial glucose homeostasis is regulated through the secretion of glucagon-like peptide 1 (glp-1) through the stimulation of insulin secretion and inhibition of glucagon secretion. |
2015-04-14 |
2023-08-13 |
human |
| Paresh Dandona, Husam Ghanim, Sanaa Abuaysheh, Kelly Green, Manav Batra, Sandeep Dhindsa, Antoine Makdissi, Reema Patel, Ajay Chaudhur. Decreased insulin secretion and incretin concentrations and increased glucagon concentrations after a high-fat meal when compared with a high-fruit and -fiber meal. American journal of physiology. Endocrinology and metabolism. vol 308. issue 3. 2015-04-14. PMID:25406260. |
this study was conducted to investigate whether a high-fat/high-carbohydrate (hfhc) meal induces an increase in plasma concentrations of glucagon, dipeptidyl peptidase-iv (dpp-iv), and cd26 expression in mononuclear cells (mnc) while reducing insulin, c-peptide, proinsulin, gip, and glp-1 concentrations. |
2015-04-14 |
2023-08-13 |
human |
| Kristina Blaslov, Tomislav Bulum, Karin Zibar, Lea Duvnja. Incretin based therapies: a novel treatment approach for non-alcoholic fatty liver disease. World journal of gastroenterology. vol 20. issue 23. 2015-04-13. PMID:24966606. |
they suggest that glp-1 analogues might have beneficial effect on hepatic steatosis acting as insulin sensitizers and directly by stimulating glp-1 receptors expressed on hepatocytes. |
2015-04-13 |
2023-08-13 |
Not clear |
| Rika Nagamine, Shiori Ueno, Masahito Tsubata, Kazuya Yamaguchi, Kinya Takagaki, Tohru Hira, Hiroshi Hara, Takanori Tsud. Dietary sweet potato (Ipomoea batatas L.) leaf extract attenuates hyperglycaemia by enhancing the secretion of glucagon-like peptide-1 (GLP-1). Food & function. vol 5. issue 9. 2015-04-13. PMID:25066255. |
third, pre-administration of sp significantly stimulated glp-1 secretion and was accompanied by enhanced insulin secretion in rats, which resulted in a reduced glycaemic response after glucose injection. |
2015-04-13 |
2023-08-13 |
mouse |
| Noemi González-Abuín, Neus Martínez-Micaelo, Maria Margalef, Mayte Blay, Anna Arola-Arnal, Begoña Muguerza, Anna Ardévol, Montserrat Pinen. A grape seed extract increases active glucagon-like peptide-1 levels after an oral glucose load in rats. Food & function. vol 5. issue 9. 2015-04-13. PMID:25088664. |
in conclusion, our results show that gspe improves glycemia through its action on glp-1 secretion and on the inhibition of the inner intestinal dpp4 activity, leading to an increase in active glp-1 levels, which, in turn, may affect the insulin release. |
2015-04-13 |
2023-08-13 |
rat |
| Kristy M Heppner, Diego Perez-Tilv. GLP-1 based therapeutics: simultaneously combating T2DM and obesity. Frontiers in neuroscience. vol 9. 2015-04-08. PMID:25852463. |
glucagon-like peptide-1 (glp-1) enhances meal-related insulin secretion, which lowers blood glucose excursions. |
2015-04-08 |
2023-08-13 |
Not clear |
| H Frances J Bligh, Ian F Godsland, Gary Frost, Karl J Hunter, Peter Murray, Katrina MacAulay, Della Hyliands, Duncan C S Talbot, John Casey, Theo P J Mulder, Mark J Berr. Plant-rich mixed meals based on Palaeolithic diet principles have a dramatic impact on incretin, peptide YY and satiety response, but show little effect on glucose and insulin homeostasis: an acute-effects randomised study. The British journal of nutrition. vol 113. issue 4. 2015-04-06. PMID:25661189. |
plasma glucose, insulin, glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic peptide (gip) and peptide yy (pyy) concentrations were measured over a period of 180 min. |
2015-04-06 |
2023-08-13 |
human |