| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J McCullough, J B Marshall, C P Bingham, B L Rice, L D Manning, S C Kalha. Carbachol modulates GIP-mediated insulin release from rat pancreatic lobules in vitro. The American journal of physiology. vol 248. issue 3 Pt 1. 1985-04-08. PMID:3883800. |
rat pancreatic lobules were used to investigate the interaction of gastric inhibitory polypeptide (gip), carbachol, glucose, and an amino acid mixture on insulin secretion. |
1985-04-08 |
2023-08-11 |
rat |
| A J McCullough, J B Marshall, C P Bingham, B L Rice, L D Manning, S C Kalha. Carbachol modulates GIP-mediated insulin release from rat pancreatic lobules in vitro. The American journal of physiology. vol 248. issue 3 Pt 1. 1985-04-08. PMID:3883800. |
at 5 mm glucose, gip (1.1 ng/ml) did not augment insulin secretion in the presence or absence of carbachol (5 x 10(-5)m) during a 210-min incubation. |
1985-04-08 |
2023-08-11 |
rat |
| A J McCullough, J B Marshall, C P Bingham, B L Rice, L D Manning, S C Kalha. Carbachol modulates GIP-mediated insulin release from rat pancreatic lobules in vitro. The American journal of physiology. vol 248. issue 3 Pt 1. 1985-04-08. PMID:3883800. |
however, at 11 mm glucose, gip did augment insulin secretion in the presence (342.5 +/- 62.0 vs. 212.5 +/- 50.5 microu . |
1985-04-08 |
2023-08-11 |
rat |
| A J McCullough, J B Marshall, C P Bingham, B L Rice, L D Manning, S C Kalha. Carbachol modulates GIP-mediated insulin release from rat pancreatic lobules in vitro. The American journal of physiology. vol 248. issue 3 Pt 1. 1985-04-08. PMID:3883800. |
during subsequent 30-min incubations, gip was increased to a supra-physiological concentration of 11 ng/ml and again augmented insulin secretion with (65.8 +/- 10.8 vs. 27.8 +/- 2.4 microu . |
1985-04-08 |
2023-08-11 |
rat |
| A J McCullough, J B Marshall, C P Bingham, B L Rice, L D Manning, S C Kalha. Carbachol modulates GIP-mediated insulin release from rat pancreatic lobules in vitro. The American journal of physiology. vol 248. issue 3 Pt 1. 1985-04-08. PMID:3883800. |
at amino acid concentrations of 21 and 211 mm, but not 2.1 mm, gip augmented insulin release but again only with carbachol present. |
1985-04-08 |
2023-08-11 |
rat |
| A J McCullough, J B Marshall, C P Bingham, B L Rice, L D Manning, S C Kalha. Carbachol modulates GIP-mediated insulin release from rat pancreatic lobules in vitro. The American journal of physiology. vol 248. issue 3 Pt 1. 1985-04-08. PMID:3883800. |
in conclusion, porcine gip augments amino acid as well as glucose-mediated insulin secretion in vitro. |
1985-04-08 |
2023-08-11 |
rat |
| K O'Dea, J Turto. Optimum effectiveness of intestinal alpha-glucosidase inhibitors: importance of uniform distribution through a meal. The American journal of clinical nutrition. vol 41. issue 3. 1985-04-02. PMID:3883743. |
when acarbose was uniformly mixed through a ground rice meal prior to digestion it produced dose-dependent reductions in the postprandial glucose, insulin and gip responses which were evident at doses as low as 12.5 mg. |
1985-04-02 |
2023-08-11 |
Not clear |
| H S Koopmans, G L Ferri, D L Sarson, J M Polak, S R Bloo. The effects of ileal transposition and jejunoileal bypass on food intake and GI hormone levels in rats. Physiology & behavior. vol 33. issue 4. 1985-03-18. PMID:6522478. |
the total-integrated plasma levels of gastrin, gip, insulin and blood glucose were significantly reduced. |
1985-03-18 |
2023-08-12 |
rat |
| A Revhaug, I Lygren, T I Lundgren, R Jorde, P G Burhol, K E Giercksk. Release of gastrointestinal peptides during E. coli endotoxinaemia. Acta chirurgica Scandinavica. vol 150. issue 7. 1985-02-11. PMID:6151326. |
in the present study the plasma levels of pancreatic polypeptide (pp), somatostatin, gastric inhibitory peptide (gip) and insulin have been measured by sensitive ria methods during e. coli endotoxin (difco) shock in six anaesthetized pigs. |
1985-02-11 |
2023-08-12 |
Not clear |
| B Amiranoff, N Vauclin-Jacques, M Laburth. Functional GIP receptors in a hamster pancreatic beta cell line, In 111: specific binding and biological effects. Biochemical and biophysical research communications. vol 123. issue 2. 1984-11-19. PMID:6091638. |
gip (10(-10) to 10(-6) m) is able to potently stimulate insulin release in in 111 cells. |
1984-11-19 |
2023-08-12 |
Not clear |
| B Amiranoff, N Vauclin-Jacques, M Laburth. Functional GIP receptors in a hamster pancreatic beta cell line, In 111: specific binding and biological effects. Biochemical and biophysical research communications. vol 123. issue 2. 1984-11-19. PMID:6091638. |
half-maximal stimulation is elicited by 10 nm gip and maximal effect reaches 3 times the basal level of insulin release. |
1984-11-19 |
2023-08-12 |
Not clear |
| M R Lucey, P D Fairclough, J A Wass, P Kwasowski, S Medbak, J Webb, L H Ree. Response of circulating somatostatin, insulin, gastrin and GIP, to intraduodenal infusion of nutrients in normal man. Clinical endocrinology. vol 21. issue 3. 1984-11-19. PMID:6148162. |
response of circulating somatostatin, insulin, gastrin and gip, to intraduodenal infusion of nutrients in normal man. |
1984-11-19 |
2023-08-12 |
human |
| M R Lucey, P D Fairclough, J A Wass, P Kwasowski, S Medbak, J Webb, L H Ree. Response of circulating somatostatin, insulin, gastrin and GIP, to intraduodenal infusion of nutrients in normal man. Clinical endocrinology. vol 21. issue 3. 1984-11-19. PMID:6148162. |
we have studied the effect of direct infusion of nutrients into the duodenum of normal subjects on circulating plasma somatostatin, insulin, gastrin and gastric inhibitory polypeptide (gip) levels. |
1984-11-19 |
2023-08-12 |
human |
| M Maletti, B Portha, M Carlquist, M Kergoat, M Laburthe, J C Marie, G Rosseli. Evidence for and characterization of specific high affinity binding sites for the gastric inhibitory polypeptide in pancreatic beta-cells. Endocrinology. vol 115. issue 4. 1984-11-01. PMID:6383787. |
it was verified that peaks a iii and b iii stimulate insulin release from the isolated perfused rat pancreas to an extent at least equal to that obtained with unlabeled gip at 10(-9) m. natural gip competitively inhibited the binding of 125i-gip in the range of 10(-10) -10(-6) m and half-maximal inhibition was observed at 1.9 +/- 0.19 x 10(-9) m gip. |
1984-11-01 |
2023-08-12 |
rat |
| C Niederau, M Berger, W Stremmel, A Starke, G Strohmeyer, R Ebert, E Siegel, W Creutzfeld. Hyperinsulinaemia in non-cirrhotic haemochromatosis: impaired hepatic insulin degradation? Diabetologia. vol 26. issue 6. 1984-10-17. PMID:6381191. |
circulating concentrations of glucose, insulin, c-peptide, glucagon, and gastric inhibitory polypeptide (gip) were measured after a 100-g oral glucose load in 10 men with idiopathic haemochromatosis in the non-cirrhotic stage of the disease. |
1984-10-17 |
2023-08-12 |
human |
| C Niederau, M Berger, W Stremmel, A Starke, G Strohmeyer, R Ebert, E Siegel, W Creutzfeld. Hyperinsulinaemia in non-cirrhotic haemochromatosis: impaired hepatic insulin degradation? Diabetologia. vol 26. issue 6. 1984-10-17. PMID:6381191. |
since pancreatic insulin secretion (c-peptide), glucagon secretion, and the entero-insulinar axis (gip) are not impaired in these non-cirrhotic patients with idiopathic haemochromatosis, iron accumulation in the hepatocytes may be responsible for the impaired insulin effect and may cause impaired hepatic insulin extraction. |
1984-10-17 |
2023-08-12 |
human |
| J B Hanks, D K Andersen, J E Wise, W S Putnam, W C Meyers, R S Jone. The hepatic extraction of gastric inhibitory polypeptide and insulin. Endocrinology. vol 115. issue 3. 1984-09-20. PMID:6378600. |
the hepatic extractions of gastric inhibitory polypeptide (gip) and insulin were determined using in vitro and in vivo methods to assess the role of the liver in gip metabolism and the possible effect of gip on the hepatic extraction of insulin. |
1984-09-20 |
2023-08-12 |
rat |
| J B Hanks, D K Andersen, J E Wise, W S Putnam, W C Meyers, R S Jone. The hepatic extraction of gastric inhibitory polypeptide and insulin. Endocrinology. vol 115. issue 3. 1984-09-20. PMID:6378600. |
during in vitro studies using the isolated perfused rat liver, infusion of gip (2000 pg/ml) alone and in combination with porcine insulin (200 microu/ml) resulted in negligible hepatic extraction of immunoreactive gip (ir-gip) in both fed and fasted animals during either physiologically euglycemic or hyperglycemic perfusions. |
1984-09-20 |
2023-08-12 |
rat |
| J B Hanks, D K Andersen, J E Wise, W S Putnam, W C Meyers, R S Jone. The hepatic extraction of gastric inhibitory polypeptide and insulin. Endocrinology. vol 115. issue 3. 1984-09-20. PMID:6378600. |
hepatic extraction of insulin and net hepatic glucose appearance were minimally affected by gip. |
1984-09-20 |
2023-08-12 |
rat |
| J B Hanks, D K Andersen, J E Wise, W S Putnam, W C Meyers, R S Jone. The hepatic extraction of gastric inhibitory polypeptide and insulin. Endocrinology. vol 115. issue 3. 1984-09-20. PMID:6378600. |
in addition, while the fed state of the animal before infusion can result in changes in the in vitro hepatic extraction of insulin, gip does not mediate these changes. |
1984-09-20 |
2023-08-12 |
rat |