| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susan Kralisch, Ulrike Lossner, Matthias Bluher, Ralf Paschke, Michael Stumvoll, Mathias Fasshaue. Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes. Regulatory peptides. vol 139. issue 1-3. 2007-04-16. PMID:17126924. |
interestingly, apelin synthesis was significantly upregulated by growth hormone (gh) and insulin in these cells whereas tnfalpha and isoproterenol did not have any effect. |
2007-04-16 |
2023-08-12 |
mouse |
| Morten B Krag, Lars C Gormsen, Zengkui Guo, Jens S Christiansen, Michael D Jensen, Søren Nielsen, Jens O L Jørgense. Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. American journal of physiology. Endocrinology and metabolism. vol 292. issue 3. 2007-04-13. PMID:17132823. |
the ability of growth hormone (gh) to stimulate lipolysis and cause insulin resistance in skeletal muscle may be causally linked, but the mechanisms remain obscure. |
2007-04-13 |
2023-08-12 |
Not clear |
| Morten B Krag, Lars C Gormsen, Zengkui Guo, Jens S Christiansen, Michael D Jensen, Søren Nielsen, Jens O L Jørgense. Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. American journal of physiology. Endocrinology and metabolism. vol 292. issue 3. 2007-04-13. PMID:17132823. |
we investigated the impact of gh on the turnover of ffa and vldl-tg, intramuscular triglyceride content (imtg), and insulin sensitivity (euglycemic clamp) in nine healthy men in a randomized double-blind placebo-controlled crossover study after 8 days treatment with (a) placebo+placebo, (b) gh (2 mg daily)+placebo, and (c) gh (2 mg daily)+acipimox (250 mgx3 daily). |
2007-04-13 |
2023-08-12 |
Not clear |
| Morten B Krag, Lars C Gormsen, Zengkui Guo, Jens S Christiansen, Michael D Jensen, Søren Nielsen, Jens O L Jørgense. Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. American journal of physiology. Endocrinology and metabolism. vol 292. issue 3. 2007-04-13. PMID:17132823. |
insulin resistance was induced by gh irrespective of concomitant acipimox (p<0.001). |
2007-04-13 |
2023-08-12 |
Not clear |
| Morten B Krag, Lars C Gormsen, Zengkui Guo, Jens S Christiansen, Michael D Jensen, Søren Nielsen, Jens O L Jørgense. Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. American journal of physiology. Endocrinology and metabolism. vol 292. issue 3. 2007-04-13. PMID:17132823. |
we conclude that these results show that gh-induced insulin resistance is associated with increased imtg and unaltered vldl-tg kinetics; we hypothesize that fat oxidation in muscle tissue is an important primary effect of gh and that circulating ffa rather than vldl-tg constitute the major source for this process; and the role of imtg in the development of gh-induced insulin resistance merits future research. |
2007-04-13 |
2023-08-12 |
Not clear |
| Raul M Luque, Manuel D Gahete, Rudy J Valentine, Rhonda D Kinema. Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. Journal of molecular endocrinology. vol 37. issue 1. 2007-04-10. PMID:16901921. |
therefore, this study examined the effects of glucocorticoids (dexamethasone (0.1-100 nm) and hydrocortisone (10 nm)), ffa (oleic and linoleic acid, 100 and 400 microm each), igf-i (0.5-50 nm), and insulin (0.5-50 nm) on gh release and gh, ghrh-receptor (ghrh-r) and ghrelin-receptor (ghs-r) mrna levels, in primary pituitary cell cultures of baboons (papio anubis) after 24 h treatment. |
2007-04-10 |
2023-08-12 |
rat |
| Raul M Luque, Manuel D Gahete, Rudy J Valentine, Rhonda D Kinema. Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. Journal of molecular endocrinology. vol 37. issue 1. 2007-04-10. PMID:16901921. |
however, as previously reported in the rat, glucocorticoids increased, while ffa, igf-i and insulin decreased gh release in baboon pituitary cell cultures, where changes in gh release were reflected by comparable changes in gh mrna levels. |
2007-04-10 |
2023-08-12 |
rat |
| Raul M Luque, Manuel D Gahete, Rudy J Valentine, Rhonda D Kinema. Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. Journal of molecular endocrinology. vol 37. issue 1. 2007-04-10. PMID:16901921. |
in addition, glucocorticoids increased, while ffa, igf-i and insulin decreased the expression of the gh stimulatory receptors, ghrh-r and ghs-r, without significantly altering cyclophilin a mrna levels. |
2007-04-10 |
2023-08-12 |
rat |
| E Kvaratskhelia, D Metreveli, K Koplatadze, D Virsaladze, R Willi. Growth hormone (GH) determinations by RIA and IFA during GH stimulation tests in children with short stature. Georgian medical news. issue 140. 2007-04-10. PMID:17179589. |
the aim of this study was to compare the results of gh determinations by radioimmunoassay (ria) and ifa, and to establish cut-off-levels for ifa in insulin tolerance test (itt). |
2007-04-10 |
2023-08-12 |
human |
| E Kvaratskhelia, D Metreveli, K Koplatadze, D Virsaladze, R Willi. Growth hormone (GH) determinations by RIA and IFA during GH stimulation tests in children with short stature. Georgian medical news. issue 140. 2007-04-10. PMID:17179589. |
all patients underwent insulin tolerance test (itt), gh was measured in duplicate by radioimmunoassay (ria, seria) and ifa (dsl). |
2007-04-10 |
2023-08-12 |
human |
| Mélanie J Chagnon, Mounib Elchebly, Noriko Uetani, Luce Dombrowski, Alan Cheng, Robert A Mooney, André Marette, Michel L Trembla. Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma. Canadian journal of physiology and pharmacology. vol 84. issue 7. 2007-03-16. PMID:16998539. |
since low dose injection of growth hormone (gh) normalized the response to exogenous insulin in rptpsigma-/- mice, we propose that the insulin hypersensitivity observed in rptpsigma-/- mice is secondary to their neuroendocrine dysplasia and gh/igf-1 deficiency. |
2007-03-16 |
2023-08-12 |
mouse |
| Y Feuermann, S J Mabjeesh, L Niv-Spector, D Levin, A Shama. Prolactin affects leptin action in the bovine mammary gland via the mammary fat pad. The Journal of endocrinology. vol 191. issue 2. 2007-03-05. PMID:17088410. |
metabolic hormones, such as gh, glucocorticoids, insulin, and leptin are responsible for coordinating the body's response to metabolic homeostasis. |
2007-03-05 |
2023-08-12 |
cattle |
| Ruben H Willemsen, Marije van Dijk, Yolanda B de Rijke, Albert W van Toorenenbergen, Paul G Mulder, Anita C Hokken-Koeleg. Effect of growth hormone therapy on serum adiponectin and resistin levels in short, small-for-gestational-age children and associations with cardiovascular risk parameters. The Journal of clinical endocrinology and metabolism. vol 92. issue 1. 2007-02-20. PMID:17003095. |
on the other hand, concern has been expressed about the effects of gh therapy on insulin sensitivity. |
2007-02-20 |
2023-08-12 |
Not clear |
| Zvi Laron, Shira Ginsberg, Pearl Lilos, Mira Arbiv, Nahum Vaisma. Body composition in untreated adult patients with Laron syndrome (primary GH insensitivity). Clinical endocrinology. vol 65. issue 1. 2007-02-16. PMID:16817829. |
to quantify body adiposity and its distribution in untreated adult patients with laron syndrome (ls; primary gh insensitivity) caused by molecular defects of the gh receptor gene or postreceptor pathways and characterized by dwarfism, obesity, insulin resistance and hyperlipidaemia. |
2007-02-16 |
2023-08-12 |
Not clear |
| Naohiko Ueno, Masaharu Uemoto, Yoshio Komatsu, Yoshiko Sato, Akio Inu. A motilin agonist, erythromycin, decreases circulating growth hormone levels in normal subjects but not in diabetic subjects. Journal of diabetes and its complications. vol 20. issue 6. 2007-02-16. PMID:17070443. |
blood glucose, plasma insulin, somatostatin (ss), and gh levels were determined. |
2007-02-16 |
2023-08-12 |
human |
| Naohiko Ueno, Masaharu Uemoto, Yoshio Komatsu, Yoshiko Sato, Akio Inu. A motilin agonist, erythromycin, decreases circulating growth hormone levels in normal subjects but not in diabetic subjects. Journal of diabetes and its complications. vol 20. issue 6. 2007-02-16. PMID:17070443. |
in diabetic subjects, there was an increase in insulin levels, but no change in blood glucose, ss, and gh levels. |
2007-02-16 |
2023-08-12 |
human |
| R Salvatori, M G Serpa, G Parmigiani, A V O Britto, J L M Oliveira, C R P Oliveira, C M Prado, C T Farias, J C Almeida, T A R Vicente, M H Aguiar-Oliveir. GH response to hypoglycemia and clonidine in the GH-releasing hormone resistance syndrome. Journal of endocrinological investigation. vol 29. issue 9. 2007-02-08. PMID:17114911. |
now, we sought to determine if we could detect a gh response to hypoglycemia (itt: insulin tolerance test) or clonidine (cl) in these patients. |
2007-02-08 |
2023-08-12 |
human |
| E Bilic, E Bilic, I Rudan, V Kusec, N Zurak, D Delimar, M Zaga. Comparison of the growth hormone, IGF-1 and insulin in cerebrospinal fluid and serum between patients with motor neuron disease and healthy controls. European journal of neurology. vol 13. issue 12. 2007-02-02. PMID:17116217. |
neurotrophic effects of the growth hormone (gh), insulin-like growth factor-1 (igf-1) and insulin on the central nervous system have become more apparent in the past decade. |
2007-02-02 |
2023-08-12 |
Not clear |
| E Bilic, E Bilic, I Rudan, V Kusec, N Zurak, D Delimar, M Zaga. Comparison of the growth hormone, IGF-1 and insulin in cerebrospinal fluid and serum between patients with motor neuron disease and healthy controls. European journal of neurology. vol 13. issue 12. 2007-02-02. PMID:17116217. |
in this study, we measured serum and cerebrospinal fluid (csf) concentrations of gh, igf-1 and insulin in 35 patients with motor neuron disease (mnd) [24 patients with definite amyotrophic lateral sclerosis (als) and 11 patients with progressive bulbar palsy] and in 40 healthy controls. |
2007-02-02 |
2023-08-12 |
Not clear |
| E Bilic, E Bilic, I Rudan, V Kusec, N Zurak, D Delimar, M Zaga. Comparison of the growth hormone, IGF-1 and insulin in cerebrospinal fluid and serum between patients with motor neuron disease and healthy controls. European journal of neurology. vol 13. issue 12. 2007-02-02. PMID:17116217. |
levels of serum concentrations of gh and igf-1 did not significantly differ between the mnd patient group and the healthy controls, while the level of insulin was significantly decreased (p = 0.0033) in the mnd patient group. |
2007-02-02 |
2023-08-12 |
Not clear |