| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Archana Vijayakumar, YingJie Wu, Nicholas J Buffin, Xiaosong Li, Hui Sun, Ronald E Gordon, Shoshana Yakar, Derek LeRoit. Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation. PloS one. vol 7. issue 9. 2013-02-15. PMID:23024761. |
mice with a skeletal muscle-specific knockout of the gh receptor (mghrko model) are protected from high fat diet (hfd)-induced insulin resistance and display increased whole-body carbohydrate utilization. |
2013-02-15 |
2023-08-12 |
mouse |
| Sebahat Turgut, Fulya Akın, Ceylan Ayada, Senay Topsakal, Emrah Yerlikaya, Günfer Turgu. The growth hormone receptor polymorphism in patients with acromegaly: relationship to BMI and glucose metabolism. Pituitary. vol 15. issue 3. 2013-02-05. PMID:21744231. |
the levels of systolic and diastolic blood pressure, bmi, fasting plasma glucose (fpg), fasting insulin, homa-ir, igf-i, gh, igfbp3, triglyceride, hdl and ldl cholesterol concentrations were evaluated. |
2013-02-05 |
2023-08-12 |
human |
| L Boero, M Manavela, T Meroño, P Maidana, L Gómez Rosso, F Brite. GH levels and insulin sensitivity are differently associated with biomarkers of cardiovascular disease in active acromegaly. Clinical endocrinology. vol 77. issue 4. 2013-02-04. PMID:22510144. |
gh levels and insulin sensitivity are differently associated with biomarkers of cardiovascular disease in active acromegaly. |
2013-02-04 |
2023-08-12 |
Not clear |
| L Boero, M Manavela, T Meroño, P Maidana, L Gómez Rosso, F Brite. GH levels and insulin sensitivity are differently associated with biomarkers of cardiovascular disease in active acromegaly. Clinical endocrinology. vol 77. issue 4. 2013-02-04. PMID:22510144. |
acromegaly is characterized by gh excess and insulin resistance. |
2013-02-04 |
2023-08-12 |
Not clear |
| Valentina Gasco, Guglielmo Beccuti, Chiara Baldini, Nunzia Prencipe, Stellina Di Giacomo, Alessandro Berton, Federica Guaraldi, Isabella Tabaro, Mauro Maccario, Ezio Ghigo, Silvia Grottol. Acylated ghrelin as a provocative test for the diagnosis of GH deficiency in adults. European journal of endocrinology. vol 168. issue 1. 2013-02-04. PMID:23082006. |
insulin tolerance test (itt) is the test of reference for the diagnosis of adult gh deficiency (ghd), although ghrh in combination with arginine (arg) or gh secretagogues are considered equally reliable tests. |
2013-02-04 |
2023-08-12 |
Not clear |
| Michael E Doche, Elena G Bochukova, Hsiao-Wen Su, Laura R Pearce, Julia M Keogh, Elana Henning, Joel M Cline, Sadia Saeed, Anne Dale, Tim Cheetham, Inês Barroso, Lawrence S Argetsinger, Stephen O'Rahilly, Liangyou Rui, Christin Carter-Su, I Sadaf Farooq. Human SH2B1 mutations are associated with maladaptive behaviors and obesity. The Journal of clinical investigation. vol 122. issue 12. 2013-02-04. PMID:23160192. |
src homology 2 b adapter protein 1 (sh2b1) modulates signaling by a variety of ligands that bind to receptor tyrosine kinases or jak-associated cytokine receptors, including leptin, insulin, growth hormone (gh), and nerve growth factor (ngf). |
2013-02-04 |
2023-08-12 |
mouse |
| Valeria Calcaterra, Annachiara Malvezzi, Rossana Toglia, Angela Berardinelli, Elena Bozzola, Mauro Bozzola, Daniela Larizz. Growth hormone deficiency in a patient with becker muscular dystrophy: a pediatric case report. Case reports in endocrinology. vol 2013. 2013-02-01. PMID:23365767. |
gh peak was evaluated after response to arginine and insulin. |
2013-02-01 |
2023-08-12 |
Not clear |
| Fumi Murata, Ichiro Horie, Takao Ando, Eriko Isomoto, Hideyuki Hayashi, Satoru Akazawa, Ikuko Ueki, Kan Nakamura, Masakazu Kobayashi, Hironaga Kuwahara, Norio Abiru, Eiji Kawasaki, Hironori Yamasaki, Atsushi Kawakam. A case of glycogenic hepatopathy developed in a patient with new-onset fulminant type 1 diabetes: the role of image modalities in diagnosing hepatic glycogen deposition including gradient-dual-echo MRI. Endocrine journal. vol 59. issue 8. 2013-01-30. PMID:22673296. |
we here demonstrate a 21-year-old male patient with new-onset fulminant t1d complicated with diabetic ketoacidosis who subsequently developed gh just after the initiation of insulin treatment. |
2013-01-30 |
2023-08-12 |
Not clear |
| Fumi Murata, Ichiro Horie, Takao Ando, Eriko Isomoto, Hideyuki Hayashi, Satoru Akazawa, Ikuko Ueki, Kan Nakamura, Masakazu Kobayashi, Hironaga Kuwahara, Norio Abiru, Eiji Kawasaki, Hironori Yamasaki, Atsushi Kawakam. A case of glycogenic hepatopathy developed in a patient with new-onset fulminant type 1 diabetes: the role of image modalities in diagnosing hepatic glycogen deposition including gradient-dual-echo MRI. Endocrine journal. vol 59. issue 8. 2013-01-30. PMID:22673296. |
moreover, the insulin requirement dramatically decreased from 168 to 80 units per day as gh improved, suggesting a potential role of gh in insulin resistance. |
2013-01-30 |
2023-08-12 |
Not clear |
| Miburge B Gois, Roberto Salvatori, Manuel H Aguiar-Oliveira, Francisco A Pereira, Carla R P Oliveira, Luiz A Oliveira-Neto, Rossana M C Pereira, Anita H O Souza, Enaldo V Melo, Francisco J A de Paul. The consequences of growth hormone-releasing hormone receptor haploinsufficiency for bone quality and insulin resistance. Clinical endocrinology. vol 77. issue 3. 2013-01-17. PMID:21995288. |
growth hormone (gh)/insulin-like growth factor (igf) axis and insulin are key determinants of bone remodelling. |
2013-01-17 |
2023-08-12 |
human |
| Ralph Decker, Kerstin Albertsson-Wikland, Berit Kriström, Maria Halldin, Jovanna Dahlgre. Decreased GH dose after the catch-up growth period maintains metabolic outcome in short prepubertal children with and without classic GH deficiency. Clinical endocrinology. vol 77. issue 3. 2013-01-17. PMID:22417085. |
previously, we found that individualized gh dosing in the catch-up period reduced the variation in fasting insulin levels by 34% compared with those receiving a standard gh dose. |
2013-01-17 |
2023-08-12 |
Not clear |
| Maja Marinkovic, Ron S Newfiel. Self-limiting hematuria following growth hormone provocative testing with arginine hydrochloride. Journal of pediatric endocrinology & metabolism : JPEM. vol 25. issue 7-8. 2013-01-15. PMID:23155712. |
evaluation of growth hormone (gh) deficiency often involves use of agents that stimulate gh secretion, such as clonidine, glucagon, insulin, levo-dopa or arginine hydrochloride. |
2013-01-15 |
2023-08-12 |
Not clear |
| D C Wathe. Mechanisms linking metabolic status and disease with reproductive outcome in the dairy cow. Reproduction in domestic animals = Zuchthygiene. vol 47 Suppl 4. 2013-01-10. PMID:22827385. |
evidence is presented for the involvement of the somatotrophic axis (gh, igf1, insulin, igfbp2) and leptin as key metabolic signalling molecules. |
2013-01-10 |
2023-08-12 |
Not clear |
| Inge Gies, Muriel Thomas, Sylvie Tenoutasse, Kathleen De Waele, Marie-Christine Lebrethon, Dominique Beckers, Inge Francois, Marc Maes, Raoul Rooman, Carine de Beaufort, Guy Massa, Jean De Scheppe. Insulin sensitivity modulates the growth response during the first year of high-dose growth hormone treatment in short prepubertal children born small for gestational age. Hormone research in paediatrics. vol 78. issue 1. 2013-01-10. PMID:22832126. |
to study the relationship between insulin sensitivity and growth response in short children born small for gestational age (sga) treated with growth hormone (gh). |
2013-01-10 |
2023-08-12 |
Not clear |
| Evangelos P Daskalopoulos, Matti A Lang, Marios Marselos, Foteini Malliou, Maria Konstand. D₂-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D. Molecular pharmacology. vol 82. issue 4. 2012-12-21. PMID:22772593. |
growth hormone (gh), prolactin, and insulin are involved in p450 regulation, and their release is under dopaminergic control. |
2012-12-21 |
2023-08-12 |
rat |
| Andrzej Bartke, Reyhan Westbroo. Metabolic characteristics of long-lived mice. Frontiers in genetics. vol 3. 2012-12-19. PMID:23248643. |
long-lived gh-resistant ghr-ko mice with targeted disruption of the gh receptor gene, as well as ames dwarf (prop1(df)) and snell dwarf (pit1(dw)) mice lacking gh (along with prolactin and tsh), are diminutive in size and have major alterations in body composition and metabolic parameters including increased subcutaneous adiposity, increased relative brain weight, small liver, hypoinsulinemia, mild hypoglycemia, increased adiponectin levels and insulin sensitivity, and reduced serum lipids. |
2012-12-19 |
2023-08-12 |
mouse |
| Caroline Barner, Maria Petersson, Britt Edén Engström, Charlotte Höyby. Effects on insulin sensitivity and body composition of combination therapy with GH and IGF1 in GH deficient adults with type 2 diabetes. European journal of endocrinology. vol 167. issue 5. 2012-12-17. PMID:22945298. |
effects on insulin sensitivity and body composition of combination therapy with gh and igf1 in gh deficient adults with type 2 diabetes. |
2012-12-17 |
2023-08-12 |
Not clear |
| Caroline Barner, Maria Petersson, Britt Edén Engström, Charlotte Höyby. Effects on insulin sensitivity and body composition of combination therapy with GH and IGF1 in GH deficient adults with type 2 diabetes. European journal of endocrinology. vol 167. issue 5. 2012-12-17. PMID:22945298. |
the aim of this trial was to evaluate the effect on insulin sensitivity and body composition of combination therapy with gh and igf1 in adults with gh deficiency (ghd) and diabetes. |
2012-12-17 |
2023-08-12 |
Not clear |
| Hana Vakili, Yan Jin, Peter A Cattin. Negative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells. The Journal of biological chemistry. vol 287. issue 40. 2012-12-14. PMID:22833680. |
insulin controls growth hormone (gh) production at multiple levels, including via a direct effect on pituitary somatotrophs. |
2012-12-14 |
2023-08-12 |
mouse |
| Hana Vakili, Yan Jin, Peter A Cattin. Negative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells. The Journal of biological chemistry. vol 287. issue 40. 2012-12-14. PMID:22833680. |
there are no data, however, on the regulation of the intact human (h) gh gene (hgh1) by insulin in non-tumor pituitary cells, but the proximal promoter region (nucleotides -496/+1) responds negatively to insulin in transfected pituitary tumor cells. |
2012-12-14 |
2023-08-12 |
mouse |