| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin-Ling Fang, Gang Shu, Zhi-Qi Zhang, Song-Bo Wang, Xiao-Tong Zhu, Ping Gao, Qian-Yun Xi, Yong-Liang Zhang, Qing-Yan Jian. Roles of α-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes. Molecular biology reports. vol 39. issue 12. 2013-04-04. PMID:23053988. |
the main purposes of this study were to investigate the effects of α-linolenic acid (ala) on the insulin-like growth factor (igf) system of porcine primary hepatocytes with or without growth hormone (gh) or insulin and the potential role of peroxisome proliferator-activated receptor α and -γ (pparα/γ) pathway. |
2013-04-04 |
2023-08-12 |
Not clear |
| V Gasco, G Beccuti, F Marotta, N Prencipe, M Maccario, J Janssen, A J van der Lely, E Ghigo, S Grottol. Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients. Journal of endocrinological investigation. vol 35. issue 4. 2013-04-02. PMID:21642764. |
somatostatin (ss) reduces insulin secretion by acting on pancreatic β-cell and also by decreasing gh secretion. |
2013-04-02 |
2023-08-12 |
Not clear |
| V Gasco, G Beccuti, F Marotta, N Prencipe, M Maccario, J Janssen, A J van der Lely, E Ghigo, S Grottol. Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients. Journal of endocrinological investigation. vol 35. issue 4. 2013-04-02. PMID:21642764. |
ss analogues in acromegaly reduce total igf-i levels inhibiting gh hypersecretion, but they also reduce free igf-i bioactivity increasing igfbp-1 levels by inducing insulin decrease. |
2013-04-02 |
2023-08-12 |
Not clear |
| V Gasco, G Beccuti, F Marotta, N Prencipe, M Maccario, J Janssen, A J van der Lely, E Ghigo, S Grottol. Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients. Journal of endocrinological investigation. vol 35. issue 4. 2013-04-02. PMID:21642764. |
in 13 acromegalic patients we studied gh, igf system, insulin, and glucagon levels at baseline and at 7 days, 1 and 6 months under treatment with slow release (sr)-lanreotide (lan) (60 mg im monthly). |
2013-04-02 |
2023-08-12 |
Not clear |
| V Gasco, G Beccuti, F Marotta, N Prencipe, M Maccario, J Janssen, A J van der Lely, E Ghigo, S Grottol. Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients. Journal of endocrinological investigation. vol 35. issue 4. 2013-04-02. PMID:21642764. |
lan did not modify the gh, insulin, glucagon, glucose, and igfbp-1 responses to arg. |
2013-04-02 |
2023-08-12 |
Not clear |
| V Gasco, G Beccuti, F Marotta, N Prencipe, M Maccario, J Janssen, A J van der Lely, E Ghigo, S Grottol. Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients. Journal of endocrinological investigation. vol 35. issue 4. 2013-04-02. PMID:21642764. |
this study shows that acromegalic patients under chronic treatment with lan display: a) inhibition of gh and total igf-i levels, not coupled to persistent decrease in free igf-i levels; b) persistent decrease in igfbp- 3 but transient decrease and increase in insulin and igfbp- 1, respectively; c) unchanged hormonal and metabolic response to arg. |
2013-04-02 |
2023-08-12 |
Not clear |
| A L Pierce, J P Breves, S Moriyama, K Uchida, E G Gra. Regulation of growth hormone (GH) receptor (GHR1 and GHR2) mRNA level by GH and metabolic hormones in primary cultured tilapia hepatocytes. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22820350. |
we investigated the effects of gh, insulin, glucagon, cortisol and triiodothyronine on ghr1 and ghr2 mrna levels in primary cultured tilapia hepatocytes. |
2013-03-21 |
2023-08-12 |
Not clear |
| A L Pierce, J P Breves, S Moriyama, K Uchida, E G Gra. Regulation of growth hormone (GH) receptor (GHR1 and GHR2) mRNA level by GH and metabolic hormones in primary cultured tilapia hepatocytes. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22820350. |
insulin suppressed stimulation of ghr2 mrna level by gh (10(-8)-10(-6) m). |
2013-03-21 |
2023-08-12 |
Not clear |
| A L Pierce, J P Breves, S Moriyama, K Uchida, E G Gra. Regulation of growth hormone (GH) receptor (GHR1 and GHR2) mRNA level by GH and metabolic hormones in primary cultured tilapia hepatocytes. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22820350. |
a single injection of gh (5 μg/g) increased liver ghr2 mrna level, and insulin injection (5 μg/g) decreased both basal and gh-stimulated ghr2 mrna levels after 6 h. in contrast, insulin and gh injection had little effect on liver ghr1 mrna level. |
2013-03-21 |
2023-08-12 |
Not clear |
| A L Pierce, J P Breves, S Moriyama, K Uchida, E G Gra. Regulation of growth hormone (GH) receptor (GHR1 and GHR2) mRNA level by GH and metabolic hormones in primary cultured tilapia hepatocytes. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22820350. |
this study shows that ghr1 and ghr2 gene expression are differentially regulated by physiological levels of gh and insulin in tilapia primary hepatocytes. |
2013-03-21 |
2023-08-12 |
Not clear |
| Naisong Chen, Lina Jin, Hengyong Zhou, Xiaojie Qi. Effects of dietary arginine levels and carbohydrate-to-lipid ratios on mRNA expression of growth-related hormones in largemouth bass, Micropterus salmoides. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22906421. |
utilizing the tissue samples and growth data collected from our two preceding researches in largemouth bass (lmb), we have investigated effects of dietary arginine (arg) levels and carbohydrate-to-lipid (cho/lip) ratios on the gh, igf-i and insulin expression in related tissues to find possible relationships between the nutrient intake, growth performance and transcript level. |
2013-03-21 |
2023-08-12 |
Not clear |
| Naisong Chen, Lina Jin, Hengyong Zhou, Xiaojie Qi. Effects of dietary arginine levels and carbohydrate-to-lipid ratios on mRNA expression of growth-related hormones in largemouth bass, Micropterus salmoides. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22906421. |
hepatic igf-i and pituitary gh mrna levels were significantly up-regulated by lower dietary arg levels from 1.94% to 3.01% and by higher levels from 2.76% to 3.01%, respectively, while brockmann body (bb)-containing tissue insulin mrna expression was not affected. |
2013-03-21 |
2023-08-12 |
Not clear |
| Naisong Chen, Lina Jin, Hengyong Zhou, Xiaojie Qi. Effects of dietary arginine levels and carbohydrate-to-lipid ratios on mRNA expression of growth-related hormones in largemouth bass, Micropterus salmoides. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22906421. |
dietary cho/lip ratios ranging from 0.32 to 5.17 (w/w) affected pituitary gh, liver igf-i and bb-containing tissue insulin mrna expression in a ratio-specific pattern. |
2013-03-21 |
2023-08-12 |
Not clear |
| Naisong Chen, Lina Jin, Hengyong Zhou, Xiaojie Qi. Effects of dietary arginine levels and carbohydrate-to-lipid ratios on mRNA expression of growth-related hormones in largemouth bass, Micropterus salmoides. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22906421. |
the lower ratios from 0.32 to 2.36 significantly up-regulated gh and insulin transcript levels, but significantly down-regulated igf-i transcript levels; the higher ratios did no longer exert any further effects on them. |
2013-03-21 |
2023-08-12 |
Not clear |
| Naisong Chen, Lina Jin, Hengyong Zhou, Xiaojie Qi. Effects of dietary arginine levels and carbohydrate-to-lipid ratios on mRNA expression of growth-related hormones in largemouth bass, Micropterus salmoides. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22906421. |
these findings indicate that in lmb dietary arg levels and cho/lip ratios regulate differentially the endocrine system of gh, igf-i and insulin at transcription level; this system, in turn, plays a fundamental role in the regulation of the nutrient metabolism and somatic growth; and that hepatic igf-i mrna abundance should be a more reliable index to assess growth and nutritional fitness than the others, at least in lmb. |
2013-03-21 |
2023-08-12 |
Not clear |
| Archana Vijayakumar, YingJie Wu, Nicholas J Buffin, Xiaosong Li, Hui Sun, Ronald E Gordon, Shoshana Yakar, Derek LeRoit. Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation. PloS one. vol 7. issue 9. 2013-02-15. PMID:23024761. |
mice with a skeletal muscle-specific knockout of the gh receptor (mghrko model) are protected from high fat diet (hfd)-induced insulin resistance and display increased whole-body carbohydrate utilization. |
2013-02-15 |
2023-08-12 |
mouse |
| Sebahat Turgut, Fulya Akın, Ceylan Ayada, Senay Topsakal, Emrah Yerlikaya, Günfer Turgu. The growth hormone receptor polymorphism in patients with acromegaly: relationship to BMI and glucose metabolism. Pituitary. vol 15. issue 3. 2013-02-05. PMID:21744231. |
the levels of systolic and diastolic blood pressure, bmi, fasting plasma glucose (fpg), fasting insulin, homa-ir, igf-i, gh, igfbp3, triglyceride, hdl and ldl cholesterol concentrations were evaluated. |
2013-02-05 |
2023-08-12 |
human |
| L Boero, M Manavela, T Meroño, P Maidana, L Gómez Rosso, F Brite. GH levels and insulin sensitivity are differently associated with biomarkers of cardiovascular disease in active acromegaly. Clinical endocrinology. vol 77. issue 4. 2013-02-04. PMID:22510144. |
gh levels and insulin sensitivity are differently associated with biomarkers of cardiovascular disease in active acromegaly. |
2013-02-04 |
2023-08-12 |
Not clear |
| L Boero, M Manavela, T Meroño, P Maidana, L Gómez Rosso, F Brite. GH levels and insulin sensitivity are differently associated with biomarkers of cardiovascular disease in active acromegaly. Clinical endocrinology. vol 77. issue 4. 2013-02-04. PMID:22510144. |
acromegaly is characterized by gh excess and insulin resistance. |
2013-02-04 |
2023-08-12 |
Not clear |
| Valentina Gasco, Guglielmo Beccuti, Chiara Baldini, Nunzia Prencipe, Stellina Di Giacomo, Alessandro Berton, Federica Guaraldi, Isabella Tabaro, Mauro Maccario, Ezio Ghigo, Silvia Grottol. Acylated ghrelin as a provocative test for the diagnosis of GH deficiency in adults. European journal of endocrinology. vol 168. issue 1. 2013-02-04. PMID:23082006. |
insulin tolerance test (itt) is the test of reference for the diagnosis of adult gh deficiency (ghd), although ghrh in combination with arginine (arg) or gh secretagogues are considered equally reliable tests. |
2013-02-04 |
2023-08-12 |
Not clear |