| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Denice S Feig, Baiju R Shah, Lorraine L Lipscombe, C Fangyun Wu, Joel G Ray, Julia Lowe, Jeremiah Hwee, Gillian L Boot. Preeclampsia as a risk factor for diabetes: a population-based cohort study. PLoS medicine. vol 10. issue 4. 2013-09-19. PMID:23610560. |
women with preeclampsia (pec) and gestational hypertension (gh) exhibit insulin resistance during pregnancy, independent of obesity and glucose intolerance. |
2013-09-19 |
2023-08-12 |
Not clear |
| F J Steyn, T Y Xie, L Huang, S T Ngo, J D Veldhuis, M J Waters, C Che. Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain. The Journal of endocrinology. vol 218. issue 2. 2013-09-17. PMID:23708999. |
increased adiposity and insulin correlates with the progressive suppression of pulsatile gh secretion during weight gain. |
2013-09-17 |
2023-08-12 |
mouse |
| F J Steyn, T Y Xie, L Huang, S T Ngo, J D Veldhuis, M J Waters, C Che. Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain. The Journal of endocrinology. vol 218. issue 2. 2013-09-17. PMID:23708999. |
to clarify this association between adiposity and gh secretion, we investigated the relationship between pulsatile gh secretion and body weight; epididymal fat mass; and circulating levels of leptin, insulin, non-esterified free fatty acids (nefas), and glucose. |
2013-09-17 |
2023-08-12 |
mouse |
| F J Steyn, T Y Xie, L Huang, S T Ngo, J D Veldhuis, M J Waters, C Che. Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain. The Journal of endocrinology. vol 218. issue 2. 2013-09-17. PMID:23708999. |
moreover, we demonstrate an inverse relationship between measures of pulsatile gh secretion and circulating levels of leptin and insulin. |
2013-09-17 |
2023-08-12 |
mouse |
| F J Steyn, T Y Xie, L Huang, S T Ngo, J D Veldhuis, M J Waters, C Che. Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain. The Journal of endocrinology. vol 218. issue 2. 2013-09-17. PMID:23708999. |
moreover, data illustrate key interactions between gh secretion and circulating levels of insulin and reflect the potential physiological role of gh in modulation of insulin-induced lipogenesis throughout positive energy balance. |
2013-09-17 |
2023-08-12 |
mouse |
| F Samadi, N J Phillips, D Blache, G B Martin, M J D'Occhi. Interrelationships of nutrition, metabolic hormones and resumption of ovulation in multiparous suckled beef cows on subtropical pastures. Animal reproduction science. vol 137. issue 3-4. 2013-09-09. PMID:23352421. |
starting at 1 week after calving, cows were monitored for bw and body condition score (bcs, biweekly) and for circulating concentrations of insulin, glucose, igf-1, gh and leptin (weekly). |
2013-09-09 |
2023-08-12 |
Not clear |
| F Samadi, N J Phillips, D Blache, G B Martin, M J D'Occhi. Interrelationships of nutrition, metabolic hormones and resumption of ovulation in multiparous suckled beef cows on subtropical pastures. Animal reproduction science. vol 137. issue 3-4. 2013-09-09. PMID:23352421. |
plasma concentrations of insulin, glucose, igf-1 and leptin were all greater (p < 0.01) for cows on ip compared with cows on sp, whilst gh did not differ. |
2013-09-09 |
2023-08-12 |
Not clear |
| Sanda Tesanović, Maja Radman, Desa Tesanović, Dubravka Jurisić Erzen, Izet Hoz. Preliminary report of hypoglycemic response in obese metabolic syndrome males treated with metformin after weight loss intervention. Collegium antropologicum. vol 37. issue 2. 2013-09-03. PMID:23940976. |
values of cortisol and gh were compared upon changes in hypothalamo-pituitary-adrenal (hpa) response to insulin induced hypoglycemia initially and after weight loss of 5% for overweight and obese participants. |
2013-09-03 |
2023-08-12 |
human |
| Manuel D Gahete, José Córdoba-Chacón, Qing Lin, Jens C Brüning, C Ronald Kahn, Justo P Castaño, Helen Christian, Raúl M Luque, Rhonda D Kinema. Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23671263. |
insulin and igf-i inhibit gh synthesis and release in vitro and in vivo by separate mechanisms. |
2013-08-28 |
2023-08-12 |
mouse |
| Manuel D Gahete, José Córdoba-Chacón, Qing Lin, Jens C Brüning, C Ronald Kahn, Justo P Castaño, Helen Christian, Raúl M Luque, Rhonda D Kinema. Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23671263. |
insulin may also play an important role in regulating gh levels because insulin, like igf-i, can suppress gh synthesis and release in primary pituitary cell cultures and insulin is negatively correlated with gh levels in vivo. |
2013-08-28 |
2023-08-12 |
mouse |
| Manuel D Gahete, José Córdoba-Chacón, Qing Lin, Jens C Brüning, C Ronald Kahn, Justo P Castaño, Helen Christian, Raúl M Luque, Rhonda D Kinema. Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23671263. |
however, understanding the relative contribution insulin and igf-i exert on controlling gh secretion has been hampered by the fact that circulating insulin and igf-i are regulated in parallel and insulin (insr) and igf-i (igfir) receptors are structurally/functionally related and ubiquitously expressed. |
2013-08-28 |
2023-08-12 |
mouse |
| Manuel D Gahete, José Córdoba-Chacón, Qing Lin, Jens C Brüning, C Ronald Kahn, Justo P Castaño, Helen Christian, Raúl M Luque, Rhonda D Kinema. Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23671263. |
to evaluate the separate roles of insulin and igf-i in directly regulating gh secretion, we used the cre/loxp system to knock down the insr and igfir in primary mouse pituitary cell cultures and found insulin-mediated suppression of gh is independent of the igfir. |
2013-08-28 |
2023-08-12 |
mouse |
| Manuel D Gahete, José Córdoba-Chacón, Qing Lin, Jens C Brüning, C Ronald Kahn, Justo P Castaño, Helen Christian, Raúl M Luque, Rhonda D Kinema. Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23671263. |
in addition, pharmacological blockade of intracellular signals in both mouse and baboon cultures revealed insulin requires different pathways from igf-i to exert a maximal inhibitory effect on gh expression/release. |
2013-08-28 |
2023-08-12 |
mouse |
| Manuel D Gahete, José Córdoba-Chacón, Qing Lin, Jens C Brüning, C Ronald Kahn, Justo P Castaño, Helen Christian, Raúl M Luque, Rhonda D Kinema. Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23671263. |
however, comparison of the pattern of gh release, gh expression, somatotrope morphometry, and pituitary explant sensitivity to acute ghrh challenge in lean sirko and sigfrko mice strongly suggests the primary role of insulin in vivo is to suppress gh release, whereas igf-i serves to regulate gh synthesis. |
2013-08-28 |
2023-08-12 |
mouse |
| Jose Córdoba-Chacón, Manuel D Gahete, Ana I Pozo-Salas, Justo P Castaño, Rhonda D Kineman, Raul M Luqu. Endogenous somatostatin is critical in regulating the acute effects of L-arginine on growth hormone and insulin release in mice. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23696563. |
l-arginine (l-arg) rapidly stimulates gh and insulin release in vivo. |
2013-08-28 |
2023-08-12 |
mouse |
| Jose Córdoba-Chacón, Manuel D Gahete, Ana I Pozo-Salas, Justo P Castaño, Rhonda D Kineman, Raul M Luqu. Endogenous somatostatin is critical in regulating the acute effects of L-arginine on growth hormone and insulin release in mice. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23696563. |
to confirm the role of endogenous sst on l-arg-induced gh and insulin release, wild-type (wt) and sst-knockout (sst-ko) mice were injected with l-arg (ip; 0.8 g/kg), and pre-/post-injection gh, insulin, and glucose levels were measured. |
2013-08-28 |
2023-08-12 |
mouse |
| Keith A Stokes, Kate L Gilbert, George M Hall, Robert C Andrews, Dylan Thompso. Different responses of selected hormones to three types of exercise in young men. European journal of applied physiology. vol 113. issue 3. 2013-08-23. PMID:22971724. |
exercise is a potent stimulus for release of growth hormone (gh), cortisol, testosterone and prolactin, and prolonged exercise inhibits insulin secretion. |
2013-08-23 |
2023-08-12 |
human |
| Keith A Stokes, Kate L Gilbert, George M Hall, Robert C Andrews, Dylan Thompso. Different responses of selected hormones to three types of exercise in young men. European journal of applied physiology. vol 113. issue 3. 2013-08-23. PMID:22971724. |
cortisol, gh, testosterone, prolactin, insulin and glucose concentrations were measured for 60 min after the four different interventions. |
2013-08-23 |
2023-08-12 |
human |
| Jenna M Apicella, Elaine C Lee, Brooke L Bailey, Catherine Saenz, Jeffrey M Anderson, Stuart A S Craig, William J Kraemer, Jeff S Volek, Carl M Mares. Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise. European journal of applied physiology. vol 113. issue 3. 2013-08-23. PMID:22976217. |
circulating gh, igf-1, cortisol, and insulin were measured. |
2013-08-23 |
2023-08-12 |
human |
| Adam Gesing, Michal M Masternak, Andrzej Lewinski, Malgorzata Karbownik-Lewinska, John J Kopchick, Andrzej Bartk. Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 68. issue 6. 2013-08-15. PMID:23197187. |
mice homozygous for the targeted disruption of the growth hormone (gh) receptor gene (gh receptor knockout; ghrko) are obese and dwarf, are characterized by a reduced weight and body size, undetectable levels of gh receptor, high concentration of serum gh, and greatly reduced plasma levels of insulin and insulin-like growth factor-i, and are remarkably long lived. |
2013-08-15 |
2023-08-12 |
mouse |