| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
because t3 stimulates gh gene expression, the effects of semisynthetic human insulin were tested on t3-induced gh secretion. |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
insulin suppression of basal gh secretion was independent of t3, as insulin (0.7 nm) suppressed basal secretion of gh by 40% in t3-depleted cells. |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
the 4-fold increase in gh secretion induced by added t3 (0.5 nm) during 72 h was suppressed up to 40% by insulin (p less than 0.001). |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
this suppression was maximal with 3.5 nm insulin and occurred after a lag period of 48 h. the previously described 20-fold synergistic stimulation of gh by t3 (0.5 nm) together with hct (1 microm) was also suppressed by insulin (3.5 nm) by 80% during 72 h of incubation. |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
the selectivity of the inhibitory effects of insulin on gh were also shown when the t3-induced suppression of prl secretion was reversed by insulin treatment. |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
the data show that physiological doses of insulin antagonize t3-induced stimulation of gh secretion and also partially block the synergistic stimulation of gh by t3 and hct. |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
as t3 and hct probably stimulate gh gene transcription at different sites, insulin may suppress gh gene expression at a more distal site. |
1985-08-29 |
2023-08-11 |
human |
| S Melmed, S M Slanin. Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3893986. |
alternatively, the inhibitory effects of insulin on t3-induced gh secretion in these cells may be posttranscriptional. |
1985-08-29 |
2023-08-11 |
human |
| T C Cree, D S Schalc. Protein utilization in growth: effect of lysine deficiency on serum growth hormone, somatomedins, insulin, total thyroxine (T4) and triiodothyronine, free T4 index, and total corticosterone. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:3926459. |
we have studied the effect of a lysine-deficient diet on the growth of young rats and on serum levels of gh, somatomedins [insulin-like growth factors (igfs) i and ii], insulin, total t4 and t3, free t4 index, and total corticosterone. |
1985-08-29 |
2023-08-11 |
rat |
| Y Nakagaw. [Clinical application of serum insulin-like growth factor I (IGF-I)(26-46) radioimmunoassay--with special reference to the relationship between IGF(26-46) and growth hormone secretion]. Nihon Naibunpi Gakkai zasshi. vol 61. issue 2. 1985-08-14. PMID:3891431. |
in order to elucidate a mutual relationship between igf-i(26-46) and growth hormone (gh) secretion, the following correlations were evaluated: 1) a correlation between igf-i(26-46) and basal gh level (n = 57), 2) a correlation between igf-i(26-46) and gh level responding to the insulin tolerance test (itt) (n = 30), 3) a correlation between igf-i(26-46) and an integrated concentration of gh(icgh) in the early sleep stage (n = 24). |
1985-08-14 |
2023-08-11 |
human |
| F Hawkins, V Sanchez Moro, M Aguirre, M Leon, D Rigopoulou, J L Martin de Nicolas, J Toled. Acromegaly and bronchial carcinoid. Effect of removal of the latter. Chest. vol 88. issue 1. 1985-08-13. PMID:4006541. |
there was pituitary enlargement with an intrasellar mass (brain computed tomography scan), high basal gh levels, and abnormal gh and other pituitary hormones response to oral glucose and a combined test (lhrh, trh, insulin). |
1985-08-13 |
2023-08-11 |
Not clear |
| E Topper, J Gertner, S Amiel, M Press, M Genel, W V Tamborlan. Deranged alpha-adrenergic regulation of growth hormone secretion in poorly controlled diabetes: reversal of the exaggerated response to clonidine after continuous subcutaneous insulin infusion. Pediatric research. vol 19. issue 6. 1985-08-07. PMID:2989759. |
as expected, continuous subcutaneous insulin infusion lowered mean 24-h plasma glucose (from 203 +/- 21 to 112 +/- 7 mg/dl, p less than 0.01) and gh (from 17.7 +/- 2.1 to 9.2 +/- 1.2 ng/ml, p less than 0.01) to values observed in normal controls. |
1985-08-07 |
2023-08-11 |
Not clear |
| E Topper, J Gertner, S Amiel, M Press, M Genel, W V Tamborlan. Deranged alpha-adrenergic regulation of growth hormone secretion in poorly controlled diabetes: reversal of the exaggerated response to clonidine after continuous subcutaneous insulin infusion. Pediatric research. vol 19. issue 6. 1985-08-07. PMID:2989759. |
in contrast, the gh response to clonidine was indistinguishable from normal after only 1 wk of intensified insulin treatment. |
1985-08-07 |
2023-08-11 |
Not clear |
| M J Lanoux, W H Cleland, C R Mendelson, B R Carr, E R Simpso. Factors affecting the conversion of androstenedione to estrogens by human fetal hepatocytes in monolayer culture. Endocrinology. vol 117. issue 1. 1985-08-02. PMID:2988922. |
of a number of hormones tested, including glucagon, insulin, angiotensin ii, acth, hcg, gh, prl, and t3, only glucocorticoids were effective in stimulating aromatase activity of human fetal hepatocytes. |
1985-08-02 |
2023-08-11 |
human |
| I Gause, S Edén, O Isaksson, M DiGirolamo, U Smit. Changes in growth hormone binding and metabolic effects of growth hormone in rat adipocytes following hypophysectomy. Acta physiologica Scandinavica. vol 124. issue 2. 1985-07-31. PMID:2990166. |
growth hormone (gh) binding and the effect of gh and insulin on glucose metabolism in rat adipocytes were studied at various time periods following hypophysectomy. |
1985-07-31 |
2023-08-11 |
rat |
| N C Steele, J P McMurtry, R W Rosebroug. Endocrine adaptations of periparturient swine to alteration of dietary energy source. Journal of animal science. vol 60. issue 5. 1985-07-29. PMID:3891705. |
blood samples from second-parity yorkshire sows fed isocaloric-isonitrogenous diets that differed by either glucose or corn oil supplying 20% of the daily metabolizable energy intake were assayed for growth hormone (gh), insulin and prolactin (prl) concentrations. |
1985-07-29 |
2023-08-11 |
Not clear |
| R Brauner, P Czernichow, R Rappaport, J Lemerle, D Sarrazin, J F Hirsch, D Renier, J M Zucke. [Statural growth following irradiation of the central nervous system for medulloblastoma of the posterior fossa. Retrospective analysis of 45 cases]. Archives francaises de pediatrie. vol 42. issue 3. 1985-07-23. PMID:4004484. |
growth retardation which occurred in 42 of 45 children, appears to be due to two major factors: 1) gh deficiency in 42 cases as assessed by the arginine insulin tolerance test. |
1985-07-23 |
2023-08-11 |
Not clear |
| I Gause, S Edé. Hormonal regulation of growth hormone binding and responsiveness in adipose tissue and adipocytes of hypophysectomized rats. The Journal of endocrinology. vol 105. issue 3. 1985-07-22. PMID:3889209. |
the different hormonal treatments were cortisone acetate, insulin, insulin plus cortisone acetate, thyroxine, thyroxine plus cortisone acetate and gh. |
1985-07-22 |
2023-08-11 |
human |
| I Gause, S Edé. Hormonal regulation of growth hormone binding and responsiveness in adipose tissue and adipocytes of hypophysectomized rats. The Journal of endocrinology. vol 105. issue 3. 1985-07-22. PMID:3889209. |
insulin treatment increased gh binding by approximately 100% and the response to gh was markedly increased. |
1985-07-22 |
2023-08-11 |
human |
| I Gause, S Edé. Hormonal regulation of growth hormone binding and responsiveness in adipose tissue and adipocytes of hypophysectomized rats. The Journal of endocrinology. vol 105. issue 3. 1985-07-22. PMID:3889209. |
the results show that insulin and thyroxine may be important for the gh receptor and the insulin-like effect of gh in adipocytes. |
1985-07-22 |
2023-08-11 |
human |