| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Roupas, R J Towns, J L Kosty. Isolated adipocytes from growth hormone-treated obese (ob/ob) mice exhibit insulin resistance. Biochimica et biophysica acta. vol 1052. issue 2. 1990-06-14. PMID:2110483. |
the genetically obese (ob/ob) mouse is a useful model for the study of the diabetogenic action of growth hormone (gh), because treatment of these animals with gh results in decreased responsiveness of their adipose tissue to insulin in vitro. |
1990-06-14 |
2023-08-11 |
mouse |
| P Roupas, R J Towns, J L Kosty. Isolated adipocytes from growth hormone-treated obese (ob/ob) mice exhibit insulin resistance. Biochimica et biophysica acta. vol 1052. issue 2. 1990-06-14. PMID:2110483. |
the induction of insulin resistance by gh has also been demonstrated in these freshly isolated ob/ob mouse adipocytes. |
1990-06-14 |
2023-08-11 |
mouse |
| P Roupas, R J Towns, J L Kosty. Isolated adipocytes from growth hormone-treated obese (ob/ob) mice exhibit insulin resistance. Biochimica et biophysica acta. vol 1052. issue 2. 1990-06-14. PMID:2110483. |
the studies to date indicate that the ob/ob mouse adipocyte system should provide a useful model for detailed studies of the cellular and molecular mechanisms of gh induced insulin resistance. |
1990-06-14 |
2023-08-11 |
mouse |
| F Barbetti, C Crescenti, M Negri, F Leonetti, A Grossi, G Tamburran. Growth hormone does not inhibit its own secretion during prolonged hypoglycemia in man. The Journal of clinical endocrinology and metabolism. vol 70. issue 5. 1990-06-14. PMID:2110574. |
we also assessed the gh response to combined and separate administration of insulin and ghrh. |
1990-06-14 |
2023-08-11 |
Not clear |
| F Barbetti, C Crescenti, M Negri, F Leonetti, A Grossi, G Tamburran. Growth hormone does not inhibit its own secretion during prolonged hypoglycemia in man. The Journal of clinical endocrinology and metabolism. vol 70. issue 5. 1990-06-14. PMID:2110574. |
the maximal gh concentration attained during the combined insulin and ghrh test was significantly higher than that with the insulin tolerance test or ghrh test (insulin plus ghrh, 71.9 +/- 13.5; insulin tolerance test, 34.2 +/- 2.9; p less than 0.025; ghrh test, 27.9 +/- 3.2; p less than 0.02), indicating an additive effect on gh secretion. |
1990-06-14 |
2023-08-11 |
Not clear |
| M M Ilondo, M Vanderschueren-Lodeweyckx, P De Meyts, E Eggermon. Serum growth hormone levels measured by radioimmunoassay and radioreceptor assay: a useful diagnostic tool in children with growth disorders? The Journal of clinical endocrinology and metabolism. vol 70. issue 5. 1990-06-14. PMID:2186059. |
in control subjects a significant (p less than 0.0001) positive correlation was found at all ages between gh levels measured by ria and rra (r = 0.69 after insulin and r = 0.77 after glucagon). |
1990-06-14 |
2023-08-11 |
human |
| A Lanzone, A M Fulghesu, S Pappalardo, C Proto, M Le Donne, C L Andreani, R Muscatello, A Caruso, S Mancus. Growth hormone and somatomedin-C secretion in patients with polycystic ovarian disease. Their relationships with hyperinsulinism and hyperandrogenism. Gynecologic and obstetric investigation. vol 29. issue 2. 1990-06-13. PMID:2110544. |
all patients had an oral glucose tolerance test (ogtt) before and after treatment with gonadotropin-releasing hormone (gnrh) agonist (buserelin 400 micrograms/die s.c. for 8 weeks) to investigate the relationship between ovarian steroidogenesis and insulin and growth hormone (gh) and insulin-like growth factor (smc) secretion. |
1990-06-13 |
2023-08-11 |
human |
| A Lanzone, A M Fulghesu, S Pappalardo, C Proto, M Le Donne, C L Andreani, R Muscatello, A Caruso, S Mancus. Growth hormone and somatomedin-C secretion in patients with polycystic ovarian disease. Their relationships with hyperinsulinism and hyperandrogenism. Gynecologic and obstetric investigation. vol 29. issue 2. 1990-06-13. PMID:2110544. |
luteinizing hormone, follicle-stimulating, estradiol, androstenedione, testosterone, dehydroepiandrosterone sulfate, cortisol, insulin, gh and smc were measured basally at the time of ogtt. |
1990-06-13 |
2023-08-11 |
human |
| A Lanzone, A M Fulghesu, S Pappalardo, C Proto, M Le Donne, C L Andreani, R Muscatello, A Caruso, S Mancus. Growth hormone and somatomedin-C secretion in patients with polycystic ovarian disease. Their relationships with hyperinsulinism and hyperandrogenism. Gynecologic and obstetric investigation. vol 29. issue 2. 1990-06-13. PMID:2110544. |
the mean fasting level and area under the curve of plasma insulin were also significantly greater in pco than in control patients (p less than 0.05), while gh and smc plasma concentrations did not differ between the groups. |
1990-06-13 |
2023-08-11 |
human |
| A Lanzone, A M Fulghesu, S Pappalardo, C Proto, M Le Donne, C L Andreani, R Muscatello, A Caruso, S Mancus. Growth hormone and somatomedin-C secretion in patients with polycystic ovarian disease. Their relationships with hyperinsulinism and hyperandrogenism. Gynecologic and obstetric investigation. vol 29. issue 2. 1990-06-13. PMID:2110544. |
gh and smc did not correlate with ideal body weight (ibw), insulin or androgens, whereas insulin correlated with both testosterone and androstenedione levels (p less than 0.05) and with ibw (p less than 0.01); after the buserelin regimen only ibw remained related to plasma insulin (p less than 0.01). |
1990-06-13 |
2023-08-11 |
human |
| D Prager, S Gebremedhin, S Melme. An insulin-induced DNA-binding protein for the human growth hormone gene. The Journal of clinical investigation. vol 85. issue 5. 1990-06-06. PMID:2185279. |
as insulin regulates transcription of the growth hormone (gh) gene, we tested nuclear extracts from unstimulated and insulin-stimulated chinese hamster ovarian (cho) cells for binding to four human gh (hgh) gene promoter oligonucleotide fragments identified as target-binding sequences by dnase i footprinting. |
1990-06-06 |
2023-08-11 |
human |
| A D Gooneratne, P A Thacker, B Laarveld, B D Murphy, K Rajkuma. Comparative effects of insulin and insulin-like growth factor-1 on follicle-stimulating hormone-induced responses in porcine granulosa cells. Steroids. vol 55. issue 3. 1990-06-01. PMID:2159194. |
the addition of only insulin, but not igf-1 or gh, enhanced progesterone secretion under both culture conditions. |
1990-06-01 |
2023-08-11 |
cattle |
| A D Gooneratne, P A Thacker, B Laarveld, B D Murphy, K Rajkuma. Comparative effects of insulin and insulin-like growth factor-1 on follicle-stimulating hormone-induced responses in porcine granulosa cells. Steroids. vol 55. issue 3. 1990-06-01. PMID:2159194. |
however, when cells were cultured in serum-free media from the time of plating, both insulin and igf-1, but not gh, potentiated the responses to fsh, but insulin was more potent than igf-1. |
1990-06-01 |
2023-08-11 |
cattle |
| S Shilo, H Shamoo. Abnormal growth hormone responses to hypoglycemia and exercise in adults with type I diabetes. Israel journal of medical sciences. vol 26. issue 3. 1990-05-31. PMID:2184144. |
during brief (30 min) exercise at 40-50% of vo2max, gh rose comparably in both groups (idd patients maintained euglycemia with basal insulin infusion). |
1990-05-31 |
2023-08-11 |
human |
| b' M Vigas, P Tat\\xc3\\xa1r, J Jurcovicov\\xc3\\xa1, D Jezov\\xc3\\xa. Glucoreceptors located in different areas mediate the hypoglycemia-induced release of growth hormone, prolactin, and adrenocorticotropin in man. Neuroendocrinology. vol 51. issue 3. 1990-05-24. PMID:2157998.' |
in young male volunteers, the changes in growth hormone (gh), prolactin (prl), and adrenocorticotropic hormone (acth) release in response to insulin injection combined with the infusion of saline, glucose, and fructose were evaluated. |
1990-05-24 |
2023-08-11 |
human |
| M D Harbison, J M Gertne. Permissive action of growth hormone on the renal response to dietary phosphorus deprivation. The Journal of clinical endocrinology and metabolism. vol 70. issue 4. 1990-05-10. PMID:2180972. |
we also assessed insulin secretion during an oral glucose load (ogtt) off and on gh. |
1990-05-10 |
2023-08-11 |
Not clear |
| M D Harbison, J M Gertne. Permissive action of growth hormone on the renal response to dietary phosphorus deprivation. The Journal of clinical endocrinology and metabolism. vol 70. issue 4. 1990-05-10. PMID:2180972. |
insulin in response to ogtt was significantly greater after gh therapy (4155 +/- 600 microu/ml.min off gh; 6504 +/- 1153 microu/ml.min on gh), although there was no difference between the low and high dose groups. |
1990-05-10 |
2023-08-11 |
Not clear |
| M D Harbison, J M Gertne. Permissive action of growth hormone on the renal response to dietary phosphorus deprivation. The Journal of clinical endocrinology and metabolism. vol 70. issue 4. 1990-05-10. PMID:2180972. |
there was no correlation between insulin levels and the change in calcitriol or between igf-i or insulin levels and the increment in tmp/gfr during gh therapy. |
1990-05-10 |
2023-08-11 |
Not clear |
| D R Garrel, L Bajard, M Harfouche, J Tourniair. Effect of sustained hyperglycemia on GHRH induced GH secretion in man. Diabete & metabolisme. vol 15. issue 5. 1990-05-10. PMID:2517116. |
no correlation was found between plasma glucose or insulin concentrations and percentage change in ghrh induced gh secretion. |
1990-05-10 |
2023-08-11 |
human |
| S K Singh, A Hatwal, J K Agrawal, H S Bajpai, S K Sing. Oral clonidine: an effective growth hormone provocative test. Indian pediatrics. vol 26. issue 10. 1990-05-10. PMID:2698383. |
the mean peak levels of gh were 11.9 +/- 2.19 ng/ml (+/- sem) after exercise, 9.82 +/- 2.81 ng/ml (+/- sem) after insulin and 15.2 +/- 2.54 ng/ml (+/- sem) after oral clonidine. |
1990-05-10 |
2023-08-11 |
Not clear |