| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Octavio Fabián Mercado-Gómez, Virginia Selene Arriaga-Ávila, Angélica Vega-García, Sandra Orozco-Suarez, Vadim Pérez-Koldenkova, Juan José Camarillo-Sánchez, Marcelino Álvarez-Herrera, Rosalinda Guevara-Guzmá. Daytime-Restricted Feeding Ameliorates Oxidative Stress by Increasing NRF2 Transcriptional Factor in the Rat Hippocampus in the Pilocarpine-Induced Acute Seizure Model. Brain sciences. vol 13. issue 10. 2023-10-30. PMID:37891811. |
nrf2 immunoreactivity and the astrocyte marker gfap also increased their colocalization under drf conditions. |
2023-10-30 |
2023-11-08 |
rat |
| Julianna M Santos, Rui Wang, Viren Bhakta, Zarek Driver, Yakhnitsa Vadim, Takaki Kiritoshi, Guangchen Ji, Volker Neugebauer, Chwan-Li She. Turmeric Bioactive Compounds Alleviate Spinal Nerve Ligation-Induced Neuropathic Pain by Suppressing Glial Activation and Improving Mitochondrial Function in Spinal Cord and Amygdala. Nutrients. vol 15. issue 20. 2023-10-30. PMID:37892476. |
increased mechanical hypersensitivity and increased gene expression of markers for microglial activation (iba-1 in the amygdala and cd11b in the spinal cord), astrocyte activation (gfap in the spinal cord), mitochondrial dysfunction (pgc1α in the amygdala), and oxidative stress (tlr4 in the spinal cord and amygdala) were found in untreated snl rats. |
2023-10-30 |
2023-11-08 |
rat |
| Xiang Cheng, Yanan Geng, Yaqun Jiang, Tong Zhao, Lingling Zhu, Yulin Den. [Characterization and identification of primarily cultured astrocytes and microglia]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 39. issue 10. 2023-10-26. PMID:37877402. |
moreover, 95.7 % of the high purity astrocytes could be obtained by astrocyte cell surface antigen-2 (acsa-2) magnetic beads separation, and there was no significant difference in the morphology of glial fibrillary acidic protein (gfap) positive astrocyte and the proportion of a1 and a2 phenotype among the p0, p1 and p2 generations of astrocyte isolated by the above methods. |
2023-10-26 |
2023-11-08 |
mouse |
| Elina Kc, Jaisan Islam, Hyong Kyu Kim, Young Seok Par. GFAP-NpHR mediated optogenetic inhibition of trigeminal nucleus caudalis attenuates hypersensitive behaviors and thalamic discharge attributed to infraorbital nerve constriction injury. The journal of headache and pain. vol 24. issue 1. 2023-10-11. PMID:37821818. |
orofacial hyperalgesia and thalamic hyperexcitability were both accompanied by medullary astrocyte hyperactivity, marked by upregulated gfap. |
2023-10-11 |
2023-10-15 |
rat |
| Xiaojun Ye, Sen Shao, Yanbo Wang, Wenwen S. Ginsenoside Rg2 alleviates neurovascular damage in 3xTg-AD mice with Alzheimer's disease through the MAPK-ERK pathway. Journal of chemical neuroanatomy. 2023-10-07. PMID:37805189. |
in particular, neun and cd31 levels were inhibited and gfap level was elevated in 3xtg-ad mice that were observed through immunofluorescence, and these levels were all antagonized by rg2, suggesting the effects of rg2 on neurovascular damage, astrocyte activation, and neuronal loss. |
2023-10-07 |
2023-10-15 |
mouse |
| Courtney Cross, Maya Davies, Emma Bateman, Elise Crame, Paul Joyce, Anthony Wignall, Amin Ariaee, Marc Gladman, Hannah Wardill, Joanne M Bowe. Fibre-rich diet attenuates chemotherapy-related neuroinflammation in mice. Brain, behavior, and immunity. 2023-09-27. PMID:37757978. |
neuroinflammation was determined by immunofluorescent analysis of astrocyte density (gfap). |
2023-09-27 |
2023-10-07 |
mouse |
| Danielle S Cahoon, Bernard M Rabin, Derek R Fisher, Barbara Shukitt-Hal. Effects of HZE-Particle Exposure Location and Energy on Brain Inflammation and Oxidative Stress in Rats. Radiation research. 2023-09-27. PMID:37758038. |
results showed that exposure to 56fe and 48ti ions produced changes in measurements of brain inflammation [glial fibrillary astrocyte protein (gfap)], oxidative stress [nadph-oxidoreductase-2 (nox2)] and antioxidant enzymes [superoxide dismutase (sod), glutathione s-transferase (gst), nuclear factor erythroid 2-related factor 2 (nrf2)]. |
2023-09-27 |
2023-10-07 |
rat |
| Sergey Kalinin, Douglas L Feinstei. Astrocyte lipocalin-2 modestly effects disease severity in a mouse model of multiple sclerosis while reducing mature oligodendrocyte protein and mRNA expression. Neuroscience letters. 2023-09-25. PMID:37748675. |
we found that clinical scores in experimental autoimmune encephalomyelitis (eae) were modestly delayed in mice with conditional knockout of lcn2 from astrocytes, associated with a small decrease in astrocyte gfap expression. |
2023-09-25 |
2023-10-07 |
mouse |
| Dandan Xu, Yayun Xu, Xinran Gao, Mengyu Yan, Chen Zhang, Xian Wu, Qingrong Xia, Jinfang G. Potential value of Interleukin-6 as a diagnostic biomarker in human MDD and the antidepressant effect of its receptor antagonist tocilizumab in lipopolysaccharide-challenged rats. International immunopharmacology. vol 124. issue Pt B. 2023-09-17. PMID:37717319. |
moreover, the immunofluorescence staining (if) technique was used to investigate the co-location of il-6 and neuron (map2), astrocyte (gfap), or microglial (iba-1). |
2023-09-17 |
2023-10-07 |
human |
| Konstantinos Chiotis, Charlotte Johansson, Elena Rodriguez-Vieitez, Nicholas J Ashton, Kaj Blennow, Henrik Zetterberg, Caroline Graff, Agneta Nordber. Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer's disease with multi-modal PET and plasma GFAP. Molecular neurodegeneration. vol 18. issue 1. 2023-09-11. PMID:37697307. |
we compared plasma gfap levels with the astrocyte tracer |
2023-09-11 |
2023-10-07 |
Not clear |
| Wiesje Pelkmans, Mahnaz Shekari, Anna Brugulat-Serrat, Gonzalo Sánchez-Benavides, Carolina Minguillón, Karine Fauria, Jose Luis Molinuevo, Oriol Grau-Rivera, Armand González Escalante, Gwendlyn Kollmorgen, Margherita Carboni, Nicholas J Ashton, Henrik Zetterberg, Kaj Blennow, Marc Suarez-Calvet, Juan Domingo Gisper. Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-09-10. PMID:37690071. |
astrocyte biomarkers gfap and ykl-40 mediate early alzheimer's disease progression. |
2023-09-10 |
2023-10-07 |
Not clear |
| Hiroshi Hasegawa, Mari Kond. Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain. Biological & pharmaceutical bulletin. vol 46. issue 9. 2023-09-04. PMID:37661398. |
another astrocyte marker, aquaporin 4 (aqp4), was also increased in the sttn with a pattern similar to that of gfap. |
2023-09-04 |
2023-09-07 |
mouse |
| Fan Xie, Li Li, Min Peng, Huan Zhan. Overexpression of miR-199a-5p improves brain injury in newborn rats with intrauterine infection via inhibition of astrocyte activation. Brain research. 2023-08-30. PMID:37648092. |
results from cell models showed that mir-199a-5p overexpression inhibited astrocyte activation, shown by enhanced cell viability, weakened cell apoptosis, and decreased gfap, il-6, and tnf-α. |
2023-08-30 |
2023-09-07 |
rat |
| Guadalupe Herrera, M Jazmín Silvero C, M Cecilia Becerra, Mercedes Lasaga, Teresa Scimonell. Modulatory role of α-MSH in hippocampal-dependent memory impairment, synaptic plasticity changes, oxidative stress, and astrocyte reactivity induced by short-term high-fat diet intake. Neuropharmacology. 2023-08-17. PMID:37591460. |
we observed astrocyte proliferation and a significant increase in the percentage of the area occupied by gfap. |
2023-08-17 |
2023-09-07 |
rat |
| Marc Alain Züst, Christian Mikutta, Ximena Omlin, Tatjana DeStefani, Marina Wunderlin, Céline Jacqueline Zeller, Kristoffer Daniel Fehér, Elisabeth Hertenstein, Carlotta L Schneider, Charlotte Elisabeth Teunissen, Leila Tarokh, Stefan Klöppel, Bernd Feige, Dieter Riemann, Christoph Nisse. The hierarchy of coupled sleep oscillations reverses with aging in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-08-16. PMID:37586871. |
in older adults, deteriorating slow wave-spindle coupling, measured using phase slope index (psi) and number of coupling events, is associated with blood plasma glial fibrillary acidic protein (gfap) levels, a marker for astrocyte activation. |
2023-08-16 |
2023-09-07 |
human |
| Dhanny Primantara Johari Santoso, Annisa Dewi Nugrahani, Amillia Siddiq, Akhmad Yogi Pramatirta, Muhammad Alamsyah Aziz, Setyorini Irianti, Adhi Pribadi, Anita Deborah Anwar, Jusuf Sulaeman Effend. Effect of maternal serum magnesium and calcium levels on umbilical glial fibrillary acidic protein levels in preterm labor. Scientific reports. vol 13. issue 1. 2023-08-16. PMID:37587163. |
magnesium can prevent astrocyte cell death and glial fibrillary acidic protein (gfap) secretion as inflammatory marker in preterm delivery. |
2023-08-16 |
2023-09-07 |
Not clear |
| Diulle Spat Peres, Fernanda Tibolla Viero, Patrícia Rodrigues, Laura de Barros Bernardes, Náthaly Andriguetto Ruviaro da Silva, Igor Ramos Lima, Gabrielli Martins, Paulo Cesar Lock Silveira, Marcella de Amorim Ferreira, Ana Merian Silva, Juliano Ferreira, Gabriela Trevisa. Characterization of Depression- and Anxiety-Like Behaviours in a Mouse Model of Relapsing-Remitting Multiple Sclerosis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-08-01. PMID:37526817. |
also, increased levels of tumour necrosis factor alpha (tnf-α), astrocyte marker (gfap), and microglial markers (iba-1) were detected in the prefrontal cortex at 35 p.i. |
2023-08-01 |
2023-08-14 |
mouse |
| Zhi-Ling Zhang, Zhi-Tong Wang, Jing Shi, Xiao-Ping Pu, Suo-Di Zha. Tetrandrine attenuates SNI-induced mechanical allodynia by inhibiting spinal CKLF1. Neuropharmacology. 2023-07-30. PMID:37517461. |
western blotting and immunofluorescence staining showed that tet significantly inhibited spinal protein expression levels of cklf1, p-nf-κb/nf-κb, p-ikk/ikk, pro-inflammatory cytokines il-1β and tnf-α, and increased protein expression levels of the anti-inflammatory cytokine il-10, while inhibiting the expression levels of microglia and astrocyte markers iba-1 and gfap of sni mice. |
2023-07-30 |
2023-08-14 |
mouse |
| Thomas Jacobus Geus, Glenn Franken, Bert Bert Jooste. Conventional, High Frequency and Differential Targeted Multiplexed Spinal Cord Stimulation in experimental Painful Diabetic Peripheral Neuropathy: pain behavior and role of the central inflammatory balance. Molecular pain. 2023-07-25. PMID:37488684. |
the inflammatory balance and glial response were analyzed in the dorsal spinal cord based on rna expression of pro- and anti-inflammatory cytokines (tnf-α, il-1ß, il-4, il-10), a microglia marker (itgam), an astrocyte marker (gfap), a t-cell marker (cd3d), microglia proliferation markers (irf8, adgre1) and p2x4, p13-mapk, bdnf signaling markers (p2x4, mapk14, bdnf). |
2023-07-25 |
2023-08-14 |
Not clear |
| Geiza Fernanda Antunes, Ana Carolina Pinheiro Campos, Daniel de Oliveira Martins, Flavia Venetucci Gouveia, Miguel José Rangel Junior, Rosana Lima Pagano, Raquel Chacon Ruiz Martine. Unravelling the Role of Habenula Subnuclei on Avoidance Response: Focus on Activation and Neuroinflammation. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445871. |
the present study aimed to shed light on the habenula subnuclei signature in avoidance behavior, evaluating the pattern of neuronal activation using fos expression and astrocyte density using gfap immunoreactivity, and comparing control, good and poor performers. |
2023-07-14 |
2023-08-14 |
Not clear |