| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clara Voelz, Lena E M Schaack, Vanessa Kogel, Cordian Beyer, Jochen Seitz, Stefanie Trin. Reversibility of Endoplasmic Reticulum Stress Markers During Long-Term Glucose Starvation in Astrocytes. Journal of molecular neuroscience : MN. vol 74. issue 2. 2024-05-16. PMID:38750341. |
a correlation between sting and the glial fibrillary acidic protein (gfap) could be established, hinting at a conditional presence of sting with a specific astrocyte phenotype. |
2024-05-16 |
2024-05-27 |
Not clear |
| Stefanie Reiter, Ting Sun, Sabine Gärtner, Stefan Pöhlmann, Michael Winkle. Development of rhesus macaque astrocyte cell lines supporting infection with a panel of viruses. PloS one. vol 19. issue 5. 2024-05-14. PMID:38743751. |
transcriptome analysis revealed that these cell lines are closely related to astrocytes, which was confirmed by immunoblot and immunofluorescence microscopy detecting expression of the astrocyte marker glial fibrillary acidic protein (gfap). |
2024-05-14 |
2024-05-27 |
monkey |
| Matthew Boulton, Ali Al-Rubai. Neuroinflammation and neurodegeneration following traumatic brain injuries. Anatomical science international. 2024-05-13. PMID:38739360. |
this review showcases a variety of markers that show reactive astrocyte presence under pathological conditions, including glial fibrillary acidic protein (gfap), crystallin alpha-b (crya-b), complement component 3 (c3) and s100a10. |
2024-05-13 |
2024-05-27 |
human |
| Adriana Fernanda Kuckartz Vizuete, Carlos-Alberto Gonçalve. Is Methylglyoxal a Potential Biomarker for the Warburg Effect Induced by the Lipopolysaccharide Neuroinflammation Model? Neurochemical research. 2024-05-10. PMID:38727985. |
our data reinforce the hypothesis that lps-induced neuroinflammation stimulates the cerebral innate immune response by increasing il-1β, a classical pro-inflammatory cytokine, and the astrocyte reactive response, via elevating s100b secretion and gfap levels. |
2024-05-10 |
2024-05-27 |
Not clear |
| Sarah A Abd El-Aal, Shorouk M El-Sayyad, Amira A El-Gazar, Sherihan Salaheldin Abdelhamid Ibrahim, Marwa A Essa, Heba M Abostate, Ghada M Raga. Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43. International immunopharmacology. vol 134. 2024-05-08. PMID:38718656. |
they also inhibited astrocyte activation, as proven by the inhibition of glial fibrillary acidic protein (gfap). |
2024-05-08 |
2024-05-27 |
rat |
| Kazuo Nakamoto, Shogo Tokuyam. Spinal lipocalin 2 as a factor in the development of central post-stroke pain. Brain research. 2024-05-05. PMID:38705557. |
lcn2 colocalized with gfap, an astrocyte marker. |
2024-05-05 |
2024-05-08 |
mouse |
| Christian Limberger, Eduardo R Zimme. Blood GFAP reflects astrocyte reactivity to Alzheimer's pathology in post-mortem brain tissue. Brain : a journal of neurology. 2024-04-18. PMID:38634672. |
blood gfap reflects astrocyte reactivity to alzheimer's pathology in post-mortem brain tissue. |
2024-04-18 |
2024-04-20 |
Not clear |
| Pascual Sánchez-Juan, Elizabeth Valeriano-Lorenzo, Alicia Ruiz-González, Ana Belén Pastor, Hector Rodrigo Lara, Francisco López-González, María Ascensión Zea-Sevilla, Meritxell Valentí, Belen Frades, Paloma Ruiz, Laura Saiz, Iván Burgueño-García, Miguel Calero, Teodoro Del Ser, Alberto Rában. Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles. Brain : a journal of neurology. 2024-04-18. PMID:38634687. |
serum gfap levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles. |
2024-04-18 |
2024-04-20 |
Not clear |
| Pascual Sánchez-Juan, Elizabeth Valeriano-Lorenzo, Alicia Ruiz-González, Ana Belén Pastor, Hector Rodrigo Lara, Francisco López-González, María Ascensión Zea-Sevilla, Meritxell Valentí, Belen Frades, Paloma Ruiz, Laura Saiz, Iván Burgueño-García, Miguel Calero, Teodoro Del Ser, Alberto Rában. Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles. Brain : a journal of neurology. 2024-04-18. PMID:38634687. |
glial fibrillary acidic protein (gfap), a proxy of astrocyte reactivity, has been proposed as biomarker of alzheimer's disease. |
2024-04-18 |
2024-04-20 |
Not clear |
| Pascual Sánchez-Juan, Elizabeth Valeriano-Lorenzo, Alicia Ruiz-González, Ana Belén Pastor, Hector Rodrigo Lara, Francisco López-González, María Ascensión Zea-Sevilla, Meritxell Valentí, Belen Frades, Paloma Ruiz, Laura Saiz, Iván Burgueño-García, Miguel Calero, Teodoro Del Ser, Alberto Rában. Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles. Brain : a journal of neurology. 2024-04-18. PMID:38634687. |
finally, serum gfap levels were revealed to be correlated with astrocyte reactivity, using the brain gfap-immunostained area as a proxy (ρ = 0.21; p = 0.02). |
2024-04-18 |
2024-04-20 |
Not clear |
| Pengjun Wang, Chen Chen, Min Sha. Vincamine alleviates brain injury by attenuating neuroinflammation and oxidative damage in a mouse model of Parkinson's disease through the NF-κB and Nrf2/HO-1 signaling pathways. Journal of biochemical and molecular toxicology. vol 38. issue 5. 2024-04-17. PMID:38629493. |
microglial and astrocyte activation was examined through immunofluorescence staining of iba-1 (microglia marker) and gfap (astrocyte marker) in the sn. |
2024-04-17 |
2024-04-19 |
mouse |
| Simin Zheng, Yunpeng Teng, Hongtao Liu, Jiaxuan He, Shaobo Zhang, Hongfei Xion. Syringaresinol attenuates Tau phosphorylation and ameliorates cognitive dysfunction induced by sevoflurane in aged rats. Journal of neuropathology and experimental neurology. 2024-04-16. PMID:38622895. |
syr treatment mitigated sevoflurane-induced cognitive decline, reduced microglial and astrocyte activation (decreased iba-1 and gfap expression), and countered neuronal apoptosis (reduced bax, cleaved-caspase3, and cleaved-parp expression). |
2024-04-16 |
2024-04-18 |
rat |
| Ji-Yong Liu, Wen-Li Zhang, Jun Liao, Li-Juan Hu, Guo-Zuo Wang, Jin-Wen Ge, Zhi-Gang Me. [Effect of Naotaifang on microglial polarization and glial scar following cerebral ischemia reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 4. 2024-04-15. PMID:38621906. |
compared with the sham, model 7 d and model 14 d groups showed cerebral infarction of different degrees, severe pathological injury of cerebral cortex and hippocampus, neurological impairment, reduced spatial learning and memory, cognitive dysfunction, severe anxiety, astrocyte hyperplasia, thickening penumbra glial scar, and up-regulated protein levels of il-1β, il-6, gfap, neurocan, phosphacan, cd206, and arg-1(p<0.01). |
2024-04-15 |
2024-04-18 |
rat |
| Ji-Yong Liu, Wen-Li Zhang, Jun Liao, Li-Juan Hu, Guo-Zuo Wang, Jin-Wen Ge, Zhi-Gang Me. [Effect of Naotaifang on microglial polarization and glial scar following cerebral ischemia reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 4. 2024-04-15. PMID:38621906. |
compared with the model group, ntf 7 d and ntf 14 d groups improved spatial learning, memory, and cognitive function, reduced anxiety, improved nerve function, reduced cerebral infarction volume, reduced astrocyte hyperplasia, thinned penumbra glial scar, down-regulated the protein levels of gfap, neurocan, phosphacan, il-6, and il-1β, and up-regulated the protein levels of il-4, cd206, and arg-1(p<0.05 or p<0.01). |
2024-04-15 |
2024-04-18 |
rat |
| Ing Chee Wee, Alina Arulsamy, Frances Corrigan, Lyndsey Collins-Prain. Long-Term Impact of Diffuse Traumatic Brain Injury on Neuroinflammation and Catecholaminergic Signaling: Potential Relevance for Parkinson's Disease Risk. Molecules (Basel, Switzerland). vol 29. issue 7. 2024-04-13. PMID:38611750. |
at 12 months post-injury, astrocyte reactivity (gfap) and microglial levels (iba1) were assessed in the striatum (str), substantia nigra (sn), and prefrontal cortex (pfc) using immunohistochemistry. |
2024-04-13 |
2024-04-15 |
rat |
| Joseph Matthew Holden, Lauren Katie Wareham, David John Calkin. Morphological and electrophysiological characterization of a novel displaced astrocyte in the mouse retina. Glia. 2024-04-09. PMID:38591270. |
in this work, we report on a novel glial population found in the inner plexiform layer and ganglion cell layer which expresses the canonical astrocyte markers gfap, s100β, connexin-43, sox2 and sox9. |
2024-04-09 |
2024-04-11 |
mouse |
| Hoang Kieu Chi Ngo, Hoang Le, Samuel J Ayer, Grace F Crotty, Michael A Schwarzschild, Rachit Baksh. Short-term lipopolysaccharide treatment leads to astrocyte activation in LRRK2 G2019S knock-in mice without loss of dopaminergic neurons. Research square. 2024-04-02. PMID:38562908. |
lps treatment caused a greater increase in the activated astrocyte marker glial fibrillary acidic protein (gfap) in the striatum and substantia nigra of lrrk2 g2019s mice than in those of wt mice. |
2024-04-02 |
2024-04-04 |
mouse |
| Nicholas J Ashton, Guglielmo Di Molfetta, Kübra Tan, Kaj Blennow, Henrik Zetterberg, Albee Messin. Plasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2024-04-01. PMID:38558318. |
alexander disease (axd) is a rare leukodystrophy caused by dominant gain-of-function mutations in the gene encoding the astrocyte intermediate filament, glial fibrillary acidic protein (gfap). |
2024-04-01 |
2024-04-04 |
Not clear |
| Jéssica Taday, Fernanda Telles Fróes, Marina Seady, Carlos Alberto Gonçalves, Marina Concli Leit. In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer's Disease. Metabolites. vol 14. issue 3. 2024-03-27. PMID:38535311. |
the dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers gfap and s100b, in addition to alterations in some of its metabolic functions. |
2024-03-27 |
2024-03-29 |
Not clear |
| Jéssica Taday, Fernanda Telles Fróes, Marina Seady, Carlos Alberto Gonçalves, Marina Concli Leit. In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer's Disease. Metabolites. vol 14. issue 3. 2024-03-27. PMID:38535311. |
we showed that mg, lps, stz and fc similarly caused astrocyte dysfunction by increasing gfap and reducing s100b secretion. |
2024-03-27 |
2024-03-29 |
Not clear |