| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiangang Zheng, Abdul Haseeb, Ziyang Wang, Hejie Wan. Network pharmacology, computational biology integrated surface plasmon resonance technology reveals the mechanism of ellagic acid against rotavirus. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555283. |
the results of network pharmacological analysis showed that there were 35 intersection proteins, among which interleukin-1β (il-1β), albumin (alb), nuclear factor kappa-b1 (nf-κb1), toll-like receptor 4 (tlr4), tumor necrosis factor alpha (tnf-α), tumor protein p53 (tp53), recombinant smad family member 3 (samd3), epidermal growth factor (egf) and interleukin-4 (il-4) were potential core targets of ea anti-rv. |
2024-03-30 |
2024-04-02 |
Not clear |
| Jean-Luc C Mougeot, Thomas E Thornburg, Braxton D Noll, Michael T Brennan, Farah Bahrani Mougeo. Regulation of STAT1 and STAT4 Expression by Growth Factor and Interferon Supplementation in Sjögren's Syndrome Cell Culture Models. International journal of molecular sciences. vol 25. issue 6. 2024-03-28. PMID:38542139. |
isgecs (immortalized salivary gland epithelial cells) and a253 cells were treated with egf, ifn-alpha, -beta, -gamma, or mitogen-activated protein kinase p38 alpha (p38-mapk) inhibitor for 0-24-48-72 h. stat1 and stat4 mrna expression was quantified by qrt-pcr. |
2024-03-28 |
2024-03-30 |
Not clear |
| Miyoung Shin, Tryston Gabriel, Robert J Coffey, Won Jae Hu. Transcriptomic Profiling Reveals Claudin 18.2 as a Diagnostic Biomarker of Ménétrier's Disease and the Role of Hedgehog Signaling in Pathogenesis. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986961. |
md patients are characterized by an increased expression of egf receptor (egfr) ligand and transforming growth factor alpha (tgf-α) in the stomach. |
2023-11-21 |
2023-11-29 |
Not clear |
| Maneesh Mohan, Ashi Mannan, Thakur Gurjeet Sing. Therapeutic implication of Sonic Hedgehog as a potential modulator in ischemic injury. Pharmacological reports : PR. 2023-06-22. PMID:37347388. |
the canonical pathway includes direct activation of interleukins (ils), angiogenic cytokines like hepatocyte growth factor (hgf), platelet-derived growth factor (pdgf), vascular endothelial growth factor (vegf), epidermal growth factor (egf), and hypoxia-inducible factor alpha (hif-), which modulate ischemia. |
2023-06-22 |
2023-08-14 |
cat |
| Taisa Nogueira Pansani, Fernanda Gonçalves Basso, Laís Medeiros Cardoso, Carlos Alberto de Souza Cost. EGF coating of titanium surfaces modulates cytokines in oral mucosal primary cells exposed to TNF-α. Journal of periodontal research. 2023-05-25. PMID:37226366. |
this study assessed the metabolism of oral mucosal cells cultured on titanium discs (ti) coated (or not) with epidermal growth factor (egf) and exposed to tumor necrosis factor alpha (tnf-α). |
2023-05-25 |
2023-08-14 |
Not clear |
| Yueqin Wang, Yu Zhang, Ruiying Chen, Xin Tia. Autocrine EGF and TGF-α promote primary and acquired resistance to ALK/c-Met kinase inhibitors in non-small-cell lung cancer. Pharmacology research & perspectives. vol 11. issue 1. 2022-12-30. PMID:36583451. |
here, we first screened growth factors to identify autocrine epidermal growth factor (egf) and transforming growth factor alpha (tgf-α) that caused primary resistance to the alk inhibitor tae684 in h3122 cells and the c-met-specific inhibitor sgx-523 in ebc-1 cells. |
2022-12-30 |
2023-08-14 |
Not clear |
| T Onel, E Yıldırım, S Dogan, A Yab. Determination of mTOR signal pathway in MMTV-TGFα mice ovary at different ages. Journal of histotechnology. 2022-08-17. PMID:35975713. |
transforming growth factor alpha (tgfα), a member of the epidermal growth factor (egf) family, regulates cell proliferation, differentiation, and development, and involves follicular development and viability. |
2022-08-17 |
2023-08-14 |
mouse |
| Emily Bontekoe, Yevgeniy Brailovsky, Debra Hoppensteadt, Jack Bontekoe, Fakiha Siddiqui, Joshua Newman, Omer Iqbal, Trent Reed, Jawed Fareed, Amir Dark. Upregulation of Inflammatory Cytokines in Pulmonary Embolism Using Biochip-Array Profiling. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. vol 27. 2021-11-19. PMID:33969714. |
using biochip-array method, this study aimed to quantify the inflammatory biomarkers such as interleukin (il)-1α, il-1β, il-2, il-4, il-6, il-8, il-10, vascular endothelial growth factor (vegf), interferon gamma (ifn-γ), tumor necrosis factor alpha (tnf-α), monocyte chemoattractant protein-1 (mcp-1), and epidermal growth factor (egf) in 109 clinically confirmed pe patients in comparison to the control group comprised of plasma samples collected from 48 healthy subjects. |
2021-11-19 |
2023-08-13 |
human |
| Min Dai, Yuen Yee Yip, George Todaro, Ingegerd Hellstrom, Karl E Hellstro. Antibodies to EGF Receptor Family Members Can Upregulate Tumor Immunity. Journal of immunotherapy (Hagerstown, Md. : 1997). vol 44. issue 9. 2021-11-01. PMID:34456294. |
we tested the hypothesis that mabs to epidermal growth factor receptor, egf, and tumor growth factor alpha (tgf-α), in addition to any other effects, can facilitate the generation of a tumor-destructive immunologic response. |
2021-11-01 |
2023-08-13 |
mouse |
| Yiqing Zheng, Mark Rayner, Ling Feng, Xiaohua Hu, Xin Zheng, Ellalane Bearth, Jizhen Li. EGF Mediates Survival of Rat Cochlear Sensory Cells via an NF-κB Dependent Mechanism In Vitro. The open neuroscience journal. vol 2. 2021-10-20. PMID:19920873. |
firstly, the presence of the egf signaling pathway was demonstrated in the developing cochlear tissues of rats and a sensory epithelial cell line (oc1): -- epidermal growth factor receptor (egfr), mitogen-activated protein kinase kinase (mapkk), i kappa b alpha (iκbα), nuclear factor kappa b (nf-κb), and b cell lymphoma 2 (bcl-2). |
2021-10-20 |
2023-08-12 |
rat |
| Benedikt Feuerecker, Philipp Biechl, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Markus Schwaiger, Wolfgang Eisenreic. Diverse metabolic response of cancer cells treated with a Scientific reports. vol 11. issue 1. 2021-10-15. PMID:33737524. |
we herein used a monoclonal antibody targeting the egf receptor (egfr) labelled with the alpha emitter |
2021-10-15 |
2023-08-13 |
Not clear |
| Octavian Munteanu, Monica Mihaela Cîrstoiu, Florin Mihail Filipoiu, Maria Narcisa Neamţu, Irina Stavarache, Tiberiu Augustin Georgescu, Ovidiu Gabriel Bratu, Gabriela Iorgulescu, Roxana Elena Bohîlţe. The etiopathogenic and morphological spectrum of anencephaly: a comprehensive review of literature. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 61. issue 2. 2021-09-16. PMID:33544785. |
etiopathogenesis of anencephaly includes several mutations in various other genes, such as: platelet-derived growth factor receptor alpha (pdgfra), cadherin epidermal growth factor (egf) laminin g (lag) seven-pass g-type receptor 1 (celsr1), vang-like 1 (vangl1) and vang-like 2 (vangl2), the last two being involved in the process of neurulation. |
2021-09-16 |
2023-08-13 |
Not clear |
| Ruttachuk Rungsiwiwut, Pranee Numchaisrika, Paweena Thuwanut, Kamthorn Pruksananond. Characterization of stem cells from human ovarian follicular fluid; a potential source of autologous stem cell for cell-based therapy. Human cell. vol 34. issue 2. 2021-08-06. PMID:33543452. |
for in vitro culture, the isolated cells were continuously cultured in a growth medium; alpha mem containing 10% fbs and epidermal growth factor (egf). |
2021-08-06 |
2023-08-13 |
human |
| An-Lun Wu, Ya-Tung Liu, Hung-Da Chou, Lan-Hsin Chuang, Kuan-Jen Chen, Yen-Po Chen, Laura Liu, Ling Yeung, Nan-Kai Wang, Yih-Shiou Hwang, Wei-Chi Wu, Chi-Chun La. Role of growth factors and internal limiting membrane constituents in müller cell migration. Experimental eye research. vol 202. 2021-04-26. PMID:33166502. |
we studied the effects of epidermal growth factor (egf), fibroblast growth factor (fgf), somatomedin (igf-1), platelet derived growth factor (pdgf), and stromal cell-derived factor-1 alpha (sdf-1α) as well as collagen iv, laminin, and fibronectin on the proliferative and migratory activities of rat müller cells in vitro. |
2021-04-26 |
2023-08-13 |
rat |
| Yue Huang, Shoma Tsubota, Nobuhiro Nishio, Yoshiyuki Takahashi, Kenji Kadomats. Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells. Cancer science. vol 112. issue 2. 2021-03-01. PMID:33277754. |
considering the effects on gene expression profile, migration ability, and chemoresistance, a combination of tumor necrosis factor alpha (tnf-α) and epidermal growth factor (egf) was sufficient to synergistically induce the adrn-to-mes transdifferentiation in sh-sy5y cells. |
2021-03-01 |
2023-08-13 |
human |
| Jordi Codony-Servat, Silvia García-Roman, Miguel Ángel Molina-Vila, Jordi Bertran-Alamillo, Santiago Viteri, Erik d'Hondt, Rafael Rosel. Anti-epidermal growth factor vaccine antibodies increase the antitumor activity of kinase inhibitors in ALK and RET rearranged lung cancer cells. Translational oncology. vol 14. issue 1. 2021-01-10. PMID:33129112. |
we found that egf and tumor growth factor alpha (tgfα) significantly decreased the antiproliferative activity of the ret inhibitor blu-667 in ccdc6-ret cells and brigatinib, alectinib and crizotinib in eml4-alk translocated cells. |
2021-01-10 |
2023-08-13 |
Not clear |
| Yuan Nong, Yujia Liang, Xiaoliu Liang, Yongming Li, Bin Yan. Pharmacological targets and mechanisms of calycosin against meningitis. Aging. vol 12. issue 19. 2020-12-19. PMID:33031061. |
as a result, all candidate and mapped biotargets of calycosin and meningitis were harvested before the vital targets of epidermal growth factor receptor (egfr), tumor necrosis factor (tnf), epidermal growth factor (egf), ataxia telangiectasia mutated protein (atm), estrogen receptor alpha (esr1), caspase-8 (casp8), nerve growth factor (ngf) of calycosin-anti-meningitis were identified. |
2020-12-19 |
2023-08-13 |
Not clear |
| Lisa A Sawicki, Leila H Choe, Katherine L Wiley, Kelvin H Lee, April M Kloxi. Isolation and Identification of Proteins Secreted by Cells Cultured within Synthetic Hydrogel-Based Matrices. ACS biomaterials science & engineering. vol 4. issue 3. 2020-10-01. PMID:29552635. |
additionally, culture medium was collected from the encapsulated hmscs, and a luminex assay was performed to identify secreted soluble factors, including vascular endothelial growth factor (vegf), endothelial growth factor (egf), basic fibroblast growth factor (fgf-2), interleukin 8 (il-8), and tumor necrosis factor alpha (tnf-α). |
2020-10-01 |
2023-08-13 |
human |
| Christin Weissleder, Samantha J Fung, Matthew W Wong, Guy Barry, Kay L Double, Glenda M Halliday, Maree J Webster, Cynthia Shannon Weicker. Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts. Frontiers in aging neuroscience. vol 8. 2020-09-29. PMID:27932973. |
epidermal growth factor receptor (egfr) and fibroblast growth factor 2 (fgf2) mrnas increased throughout adulthood, while transforming growth factor alpha (tgfα), egf, erb-b2 receptor tyrosine kinase 4 (erbb4) and fgf receptor 1 (fgfr1) mrnas were unchanged across adulthood. |
2020-09-29 |
2023-08-13 |
human |
| Michael James Dixon, David Foreman, Seth Schor, Mark William, James Ferguso. Epidermal growth factor and transforming growth factor alpha regulate extracellular matrix production by embryonic mouse palatal mesenchymal cells cultured on a variety of substrata. Roux's archives of developmental biology : the official organ of the EDBO. vol 203. issue 3. 2020-09-28. PMID:28305731. |
addition of 10 ng/ml epidermal growth factor (egf) or transforming growth factor alpha (tgfα) stimulated the proliferation of those cells cultured on plastic or on collagen but not those cultured within collagen gels. |
2020-09-28 |
2023-08-13 |
mouse |