| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Wang, Ying Miao, Qin Wa. Association Between Triglyceride-Glucose Index and Waist-To-Hip Ratio with Type 2 Diabetic Retinopathy in the Chinese Population: A Cross-Sectional Study. Endocrine research. 2024-06-08. PMID:38850265. |
the triglyceride-glucose (tyg) index serves as a convenient indicator of insulin resistance, which has been demonstrated to be associated with diabetic retinopathy(dr). |
2024-06-08 |
2024-06-11 |
Not clear |
| Amani M Al-Adsani, Khaled K Al-Qatta. Among Other Tissues, Short-Term Garlic Oral Treatment Incrementally Improves Indicants of Only Pancreatic Islets of Langerhans Histology and Insulin mRNA Transcription and Synthesis in Diabetic Rats. Biology. vol 13. issue 5. 2024-05-26. PMID:38785837. |
the source, mrna transcription, and synthesis of insulin in the pancreas, in addition to the bile duct and liver, in streptozotocin (stz)-induced diabetic rats (dr) in response to garlic oral treatment are not yet clear. |
2024-05-26 |
2024-05-27 |
rat |
| Lanchu Yu, Bingqing L. Association Between Triglyceride-Glucose Index and Diabetic Retinopathy: A Meta-Analysis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2024-04-26. PMID:38670124. |
the objective of this study was to assess the relationship between the triglyceride-glucose (tyg) index, a recently proposed marker of insulin resistance, and the occurrence of diabetic retinopathy (dr), a complication associated with cardiovascular risk. |
2024-04-26 |
2024-04-29 |
Not clear |
| T Y Alvin Liu, Julia Shpigel, Fatima Khan, Kerry Smith, Laura Prichett, Roomasa Channa, Sarah Kanbour, Marissa Jones, Mohammed S Abusamaan, Aniket Sidhaye, Nestoras Mathioudakis, Risa M Wol. Use of Diabetes Technologies and Retinopathy in Adults With Type 1 Diabetes. JAMA network open. vol 7. issue 3. 2024-03-06. PMID:38446483. |
outcomes of continuous glucose monitoring (cgm) and insulin pump use in dr are not well understood. |
2024-03-06 |
2024-03-08 |
Not clear |
| Yu-Xin Xu, Sheng-Dan Pu, Yi-Tong Zhang, Xue-Wei Tong, Xiao-Tong Sun, Yong-Yan Shan, Xin-Yuan Ga. Insulin resistance is associated with the presence and severity of retinopathy in patients with type 2 diabetes. Clinical & experimental ophthalmology. 2023-12-22. PMID:38130181. |
to assess the relationship between novel insulin resistance (ir) indices and the presence and severity of diabetic retinopathy (dr) in patients with type 2 diabetes. |
2023-12-22 |
2023-12-24 |
Not clear |
| Yan Guo, Xiaoquan Zheng, Hongwu He, Suilian Zhen. Retinal Microvasculopathy with Different Insulin Infusion Therapies in Children with Type 1 Diabetes Mellitus without Clinical Diabetic Retinopathy. Retina (Philadelphia, Pa.). 2023-12-21. PMID:38127867. |
to explore the characteristics and associated factors of retinal microvasculopathy and neurodegeneration with different insulin therapies in children with type 1 diabetes mellitus (t1dm) children without diabetic retinopathy (dr). |
2023-12-21 |
2023-12-24 |
Not clear |
| Isao Shimokaw. Mechanisms underlying retardation of aging by dietary energy restriction. Pathology international. 2023-11-17. PMID:37975408. |
npy was necessary for dr to exert its effects in male and female mice; meanwhile, under al conditions, the loss of npy prevented obesity and insulin resistance only in female mice. |
2023-11-17 |
2023-11-20 |
mouse |
| Smilja Todorovic, Valentina Simeunovic, Milica Prvulovic, Tamara Dakic, Tanja Jevdjovic, Srdjan Sokanovic, Selma Kanazir, Aleksandra Mladenovi. Dietary restriction alters insulin signaling pathway in the brain. BioFactors (Oxford, England). 2023-11-17. PMID:37975613. |
because the effects of dr on insulin signaling in the brain have been poorly studied, we decided to examine the effects of dr that differed in onset and duration: long-term dr (ltdr), medium-term dr (mtdr), and short-term dr (stdr) on the expression of proteins involved in insulin signaling in the hippocampus of 18- and 24-month-old male wistar rats. |
2023-11-17 |
2023-11-20 |
rat |
| Smilja Todorovic, Valentina Simeunovic, Milica Prvulovic, Tamara Dakic, Tanja Jevdjovic, Srdjan Sokanovic, Selma Kanazir, Aleksandra Mladenovi. Dietary restriction alters insulin signaling pathway in the brain. BioFactors (Oxford, England). 2023-11-17. PMID:37975613. |
significantly changed insulin content in the hippocampus, together with altered insulin signaling were found under the influence of dr, but the outcome was highly dependent on the onset and duration of dr. |
2023-11-17 |
2023-11-20 |
rat |
| Mahboobeh Yeganeh-Hajahmadi, Mehrnaz Mehrabani, Mojdeh Esmaili, Mitra Shadkam Farokhi, Mojgan Sanjar. Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin. Scientific reports. vol 13. issue 1. 2023-10-12. PMID:37828117. |
insulin is proved to have angiogenic ability thereby may worsen the diabetic retinopathy (dr) progression. |
2023-10-12 |
2023-10-15 |
Not clear |
| Mahboobeh Yeganeh-Hajahmadi, Mehrnaz Mehrabani, Mojdeh Esmaili, Mitra Shadkam Farokhi, Mojgan Sanjar. Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin. Scientific reports. vol 13. issue 1. 2023-10-12. PMID:37828117. |
since protamine was introduced as an inhibitor of the apelin receptor, we hypothesized that use of protaminated insulin instead of non-protaminated insulin can decrease the negative role of insulin in progression of dr. firstly, the incidence of dr was compared among three diabetic patient groups: an oral medication, non-protaminated insulin, and protaminated insulin (pins). |
2023-10-12 |
2023-10-15 |
Not clear |
| Mahboobeh Yeganeh-Hajahmadi, Mehrnaz Mehrabani, Mojdeh Esmaili, Mitra Shadkam Farokhi, Mojgan Sanjar. Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin. Scientific reports. vol 13. issue 1. 2023-10-12. PMID:37828117. |
in clinical study, the chance of developing dr was 8.5 and 4.1 times higher in insulin group and pins groups compared with oral group respectively. |
2023-10-12 |
2023-10-15 |
Not clear |
| Mahboobeh Yeganeh-Hajahmadi, Mehrnaz Mehrabani, Mojdeh Esmaili, Mitra Shadkam Farokhi, Mojgan Sanjar. Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin. Scientific reports. vol 13. issue 1. 2023-10-12. PMID:37828117. |
insulin group had a chance of 9.5-folds of non-proliferative dr compared to oral group. |
2023-10-12 |
2023-10-15 |
Not clear |
| E J Stinson, C M Mitchell, H C Looker, J Krakoff, D C Chan. Higher glucose and insulin responses to a mixed meal are associated with increased risk of diabetic retinopathy in Indigenous Americans. Journal of endocrinological investigation. 2023-09-08. PMID:37684485. |
we aimed to identify glucose and insulin responses to a mixed meal tolerance test (mmtt) that predict the development of diabetic retinopathy (dr) and compare the predictive abilities with the oral glucose tolerance test (ogtt). |
2023-09-08 |
2023-10-07 |
Not clear |
| Mădălina Moldovan, Ana-Maria Păpurică, Mara Muntean, Raluca Maria Bungărdean, Dan Gheban, Bianca Moldovan, Gabriel Katona, Luminița David, Gabriela Adriana Fili. Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts. Metabolites. vol 13. issue 8. 2023-08-25. PMID:37623898. |
insulin, rutin, and aunpsr were administered to an early, six-week rat model of dr and ca. |
2023-08-25 |
2023-09-07 |
rat |
| Ishani Kapoor, Swara M Sarvepalli, David D'Alessio, Dilraj S Grewal, Majda Hadziahmetovi. GLP-1 Receptor Agonists and Diabetic Retinopathy: A Meta-Analysis of Randomized Clinical Trials. Survey of ophthalmology. 2023-07-16. PMID:37454782. |
compared to insulin, glp-1 ra use protected against late-stage dr (rr = 0.38, 95% ci [0.15, 0.98]). |
2023-07-16 |
2023-08-14 |
Not clear |
| Ishani Kapoor, Swara M Sarvepalli, David D'Alessio, Dilraj S Grewal, Majda Hadziahmetovi. GLP-1 Receptor Agonists and Diabetic Retinopathy: A Meta-Analysis of Randomized Clinical Trials. Survey of ophthalmology. 2023-07-16. PMID:37454782. |
analysis of individual glp-1 ras showed albiglutide is responsible for these trends, as it is significantly associated with a higher risk of early-stage dr (rr = 2.18, 95% ci [1.01, 4.67]) compared to placebo and a lower risk of late-stage dr (rr = 0.25, 95% ci [0.09, 0.70]) compared to insulin. |
2023-07-16 |
2023-08-14 |
Not clear |
| Yue Cai, Yongbo Kan. Gut microbiota and metabolites in diabetic retinopathy: Insights into pathogenesis for novel therapeutic strategies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 164. 2023-06-10. PMID:37301133. |
finally, the microbiota-gut-retina axis is presented to help us understand the mechanisms underlying the effect of gut microbiota on triggering or promoting dr, with a focus on the key pathways (e.g., bacterial dysbiosis and gut barrier dysfunction) that promote inflammation, insulin resistance, retinal cell and acellular capillary damage, leading to dr. based on these data, we can hope to achieve a non-invasive, inexpensive treatment for dr by modulating the gut microbiota, either by supplementation with probiotics or by fecal transplantation. |
2023-06-10 |
2023-08-14 |
Not clear |
| Zhaoxia Zheng, Meng Yan, Duo Zhang, Lu Li, Lina Zhan. Quantitatively evaluating the relationships between insulin resistance and retinal neurodegeneration with optical coherence tomography in early type 2 diabetes mellitus. Ophthalmic research. 2023-06-04. PMID:37271122. |
to quantitatively assess retinal neurodegenerative changes with optical coherence tomography (cirrus hd-oct) in type 2 diabetes mellitus (t2dm) patients without diabetic retinopathy (dr), and evaluate their relationships with insulin resistance (ir) and associated systemic indicators. |
2023-06-04 |
2023-08-14 |
Not clear |
| Stéphanie Larose, Christopher Filliter, Robert W Platt, Oriana H Y Yu, Kristian B Filio. Long-acting insulin analogues and the risk of diabetic retinopathy among patients with type 2 diabetes: A population-based cohort study. Diabetes, obesity & metabolism. 2023-05-11. PMID:37165960. |
to determine whether the use of long-acting insulin analogues is associated with an increased risk of incident diabetic retinopathy (dr) among patients with type 2 diabetes. |
2023-05-11 |
2023-08-14 |
Not clear |