| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tzu-Yi Lin, Eugene Yu-Chuan Kang, Nan-Kai Wang, Je-Ho Kang, Kuan-Jen Chen, Wei-Chi Wu, Chi-Chun Lai, Yih-Shiou Hwan. Association Between Pentoxifylline Use and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Multi-Institutional Cohort Study. Biomedical journal. 2024-07-21. PMID:39033962. |
despite the improvement of capillary blood flow velocity in retina after pentoxifylline use, no evidence has been provided to prove the protective effect for diabetic retinopathy (dr). |
2024-07-21 |
2024-07-24 |
Not clear |
| Lifang Bai, Ying Wan. Mesenchymal stem cells-derived exosomes alleviate senescence of retinal pigment epithelial cells by activating PI3K/AKT-Nrf2 signaling pathway in early diabetic retinopathy. Experimental cell research. 2024-07-17. PMID:39019426. |
additionally, mscs-exos improved the functional and structural integrity of the retina in dr mice. |
2024-07-17 |
2024-07-20 |
mouse |
| Jinyan Zhang, Qianqian Huo, Deyu Xia, Mingfang Wang, Xiuyun L. Advances in application of swept-source optical coherence tomography angiography in diagnosis and treatment of diabetic retinopathy. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983076. |
it can accurately present the various levels of the retina, choriocapillaris, macula, and the optic papillary microcirculation, which is new to the diagnosis and prognosis of dr. |
2024-07-10 |
2024-07-12 |
Not clear |
| Lu Ye, Yixiu Chen, Wendong Gu, Jun Shao, Yu Xi. Hsa_circ_0004776 regulates the retina neovascularization in progression of diabetic retinopathy Archives of physiology and biochemistry. 2024-07-08. PMID:38975651. |
hsa_circ_0004776 regulates the retina neovascularization in progression of diabetic retinopathy the aim of this work was to identify the regulatory function of hsa_circ_0004776 in the progression of diabetic retinopathy (dr). |
2024-07-08 |
2024-07-11 |
Not clear |
| Qian Yang, Marina Yasvoina, Abraham Olvera-Barrios, Joel Mendes, Meidong Zhu, Cathy Egan, Adnan Tufail, Marcus Fruttige. Deciphering the connection between microvascular damage and neurodegeneration in early diabetic retinopathy. Diabetes. 2024-07-05. PMID:38968415. |
diabetic retinopathy (dr), a common diabetes complication leading to vision loss, presents early clinical signs linked to retinal vasculature damage, affecting the neural retina at advanced stages. |
2024-07-05 |
2024-07-08 |
human |
| Qian Yang, Marina Yasvoina, Abraham Olvera-Barrios, Joel Mendes, Meidong Zhu, Cathy Egan, Adnan Tufail, Marcus Fruttige. Deciphering the connection between microvascular damage and neurodegeneration in early diabetic retinopathy. Diabetes. 2024-07-05. PMID:38968415. |
to study the earliest stages of dr we performed histological phenotyping and quantitative analysis on postmortem retinas from 10 donors with diabetes and without signs of dr (such as microaneurysms and haemorrhages), plus 3 controls and 1 dr case, focusing on capillary loss in the deeper (dvp) and superficial vascular plexuses (svp) and neural retina effects. |
2024-07-05 |
2024-07-08 |
human |
| Qian Yang, Marina Yasvoina, Abraham Olvera-Barrios, Joel Mendes, Meidong Zhu, Cathy Egan, Adnan Tufail, Marcus Fruttige. Deciphering the connection between microvascular damage and neurodegeneration in early diabetic retinopathy. Diabetes. 2024-07-05. PMID:38968415. |
in conclusion, our findings demonstrate a novel histological biomarker for early-stage diabetes-related damage in human postmortem retina, common in people with diabetes before clinical dr diagnosis. |
2024-07-05 |
2024-07-08 |
human |
| Shivakumar K Reddy, Vasudha Devi, Amritha T M Seetharaman, S Shailaja, Kumar M R Bhat, Rajashekhar Gangaraju, Dinesh Upadhy. Cell and molecular targeted therapies for diabetic retinopathy. Frontiers in endocrinology. vol 15. 2024-07-01. PMID:38948520. |
this review explores distinctive pathophysiological phenomena of dr and identifiable cell types and molecules that could be targeted to mitigate the chronic changes occurring in the retina due to diabetes mellitus. |
2024-07-01 |
2024-07-03 |
human |
| Bo Li, Xu Zhao, Wanrun Xie, Zhenzhen Hong, Ye Cao, Yan Ding, Yi Zhan. Causal association of circulating metabolites with diabetic retinopathy: a bidirectional Mendelian randomization analysis. Frontiers in endocrinology. vol 15. 2024-05-27. PMID:38800471. |
the retina is a highly metabolically active tissue, and there is a lack of clarity about the relationship between metabolites and diabetic retinopathy (dr). |
2024-05-27 |
2024-05-31 |
Not clear |
| Gustavo Barreto Melo, Luis Filipe Nakayama, Viviane Santos Cardoso, Lucas Andrade Dos Santos, Fernando Korn Malerb. Synchronous Diagnosis of Diabetic Retinopathy by a Handheld Retinal Camera, Artificial Intelligence, and Simultaneous Specialist Confirmation. Ophthalmology. Retina. 2024-05-16. PMID:38750937. |
this study presents a proof of concept for utilizing a portable handheld retinal camera with an embedded artificial intelligence (ai) platform, complemented by a synchronous remote confirmation by retina specialists, for dr screening in an underserved rural area. |
2024-05-16 |
2024-05-27 |
Not clear |
| Beatriz Martins, Maria Pires, António Francisco Ambrósio, Henrique Girão, Rosa Fernande. Contribution of extracellular vesicles for the pathogenesis of retinal diseases: shedding light on blood-retinal barrier dysfunction. Journal of biomedical science. vol 31. issue 1. 2024-05-11. PMID:38730462. |
retinal degenerative diseases, including diabetic retinopathy (dr) and age-related macular degeneration (amd), loom as threats to vision, causing detrimental effects on the structure and function of the retina. |
2024-05-11 |
2024-05-27 |
Not clear |
| Alexandra-Ioana Dănilă, Laura Andreea Ghenciu, Emil Robert Stoicescu, Sorin Lucian Bolintineanu, Roxana Iacob, Mihai-Alexandru Săndesc, Alexandra Corina Fau. Aldose Reductase as a Key Target in the Prevention and Treatment of Diabetic Retinopathy: A Comprehensive Review. Biomedicines. vol 12. issue 4. 2024-04-27. PMID:38672103. |
one of the key mechanisms related to dr pathogenesis is the polyol pathway, through which aldose reductase (ar) catalyzes the conversion of glucose to sorbitol within various tissues, including the retina, lens, ciliary body and iris. |
2024-04-27 |
2024-04-29 |
Not clear |
| Luwei Cai, Mengxue Xia, Fang Zhan. Redox Regulation of Immunometabolism in Microglia Underpinning Diabetic Retinopathy. Antioxidants (Basel, Switzerland). vol 13. issue 4. 2024-04-27. PMID:38671871. |
microglia, resident immune cells in the retina, are recognized as crucial drivers in the dr process. |
2024-04-27 |
2024-04-29 |
Not clear |
| Xueli Yang, Xiaoli W. The impact of sestrin2 on reactive oxygen species in diabetic retinopathy. Cell biochemistry and function. vol 42. issue 4. 2024-04-26. PMID:38666564. |
our results highlighted the inhibitory effect of sestrin2 in the damage of retina, thus presenting a novel therapeutic sight for dr. |
2024-04-26 |
2024-04-28 |
rat |
| Stela Vujosevic, Camilla Alovisi, Gabriele Piccoli, Marco Brambilla, Emanuele Torti, Elisa Marenzi, Francesco Leporati, Livio Luzi, Paolo Nucc. Severity of Disorganization of Retinal Layers and Visual Function Impairment in Diabetic Retinopathy. Ophthalmology. Retina. 2024-04-11. PMID:38604502. |
to evaluate best corrected visual acuity (bcva), retina sensitivity (rs) and fixation impairment by microperimetry (mp) due to the presence and severity of disorganization of inner and outer retinal layers (dril/drol) and ischemia in oct/oct-angiography(oct-a) in diabetic retinopathy (dr). |
2024-04-11 |
2024-04-14 |
Not clear |
| Roberto Romero-Oraá, María Herrero-Tudela, María I López, Roberto Hornero, María Garcí. Attention-based deep learning framework for automatic fundus image processing to aid in diabetic retinopathy grading. Computer methods and programs in biomedicine. vol 249. 2024-04-07. PMID:38583290. |
as a novelty, we propose an end-to-end deep learning framework for automatic dr grading (5 severity degrees) based on separating the attention of the dark structures from the bright structures of the retina. |
2024-04-07 |
2024-04-10 |
human |
| Xiaoling Luo, Qihao Xu, Zhihua Wang, Chao Huang, Chengliang Liu, Xiaopeng Jin, Jianguo Zhan. A Lesion-Fusion Neural Network for Multi-View Diabetic Retinopathy Grading. IEEE journal of biomedical and health informatics. vol PP. 2024-04-03. PMID:38568769. |
most previous dr grading models are trained using the dataset of single-field fundus images, but the entire retina cannot be fully visualized in a single field of view. |
2024-04-03 |
2024-04-06 |
Not clear |
| Yanyan Cui, Dongfan Feng, Changlong Wu, Ping Wang, Ruoxi Cui, Xiaokun Wang, Weiwei Chang, Weiwei Shang, Bojun Zhao, Jing Liu, Xuejiao Qi. Quantitative assessment of OCT and OCTA parameters in diabetic retinopathy with and without macular edema: single-center cross-sectional analysis. Frontiers in endocrinology. vol 14. 2024-03-25. PMID:38523868. |
the retinal and choroidal parameters were analyzed to understand the impairment of microcirculation of both retina and choroid in patients with diabetic retinopathy (dr). |
2024-03-25 |
2024-03-27 |
Not clear |
| Siva S R Iyer, Nila S Radhakrishnan, Ramak Roohipourmoallai, Cynthia M Guerin, Jeremy S Maylath, Nickolas Garso. Chronic ocular small vessel disease: An overview of diabetic retinopathy and its relationship with cardiovascular health. American heart journal plus : cardiology research and practice. vol 29. 2024-03-21. PMID:38510674. |
diabetic retinopathy (dr) is a potentially blinding disease originating from small vessel damage in the retina in chronic hyperglycemic states. |
2024-03-21 |
2024-03-23 |
Not clear |
| Shuyu Tang, Mengling Huang, Ruixuan Wang, Ming Li, Ning Dong, Ronghan Wu, Zailong Chi, Ling Ga. Drp1-dependent mitochondrial fragmentation mediates photoreceptor abnormalities in type 1 diabetic retina. Experimental eye research. 2024-03-11. PMID:38467174. |
given the pivotal role of dysfunctional mitochondria and oxidative stress in early dr, our objective was to observe mitochondria-related alterations in the neural retina of type one diabetic mellitus mice with no evidence of dr (t1dm-ndr). |
2024-03-11 |
2024-03-14 |
mouse |