Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Andrea Contestabile, Barbara Greco, Diego Ghezzi, Valter Tucci, Fabio Benfenati, Laura Gasparin. Lithium rescues synaptic plasticity and memory in Down syndrome mice. The Journal of clinical investigation. vol 123. issue 1. 2013-03-11. PMID:23202733. |
we report that, in the ts65dn mouse model of ds, chronic administration of lithium, a clinically used mood stabilizer, promoted the proliferation of neuronal precursor cells through the pharmacological activation of the wnt/β-catenin pathway and restored adult neurogenesis in the hippocampal dentate gyrus (dg) to physiological levels. |
2013-03-11 |
2023-08-12 |
mouse |
Xiao-Cai Sun, Li Li, Min Zhang, Wen-Bin Li, Qing-Jun Li, Li Zha. [Division of CA1, CA3 and DG regions of the hippocampus of Wistar rat]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 28. issue 2. 2013-03-04. PMID:22737927. |
[division of ca1, ca3 and dg regions of the hippocampus of wistar rat]. |
2013-03-04 |
2023-08-12 |
rat |
Xiao-Cai Sun, Li Li, Min Zhang, Wen-Bin Li, Qing-Jun Li, Li Zha. [Division of CA1, CA3 and DG regions of the hippocampus of Wistar rat]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 28. issue 2. 2013-03-04. PMID:22737927. |
division of the ca1, ca3 and dentate gyrus (dg) regions of the hippocampus of wistar rat under the stereomicroscope. |
2013-03-04 |
2023-08-12 |
rat |
Tao Tan, Bao-Liang Zhang, Xin Tia. [Chronic effects of oligomeric Aβ(1-42) on hippocampal synaptic plasticity in vivo]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 3. 2013-02-21. PMID:21681340. |
twenty four sprague-dawley rats at 2.5 months of age were randomly divided into ad and control groups, and were bilaterally injected with 5 μg oligomeric aβ(1-42) or normal saline into dentate gyrus (dg) of hippocampus. |
2013-02-21 |
2023-08-12 |
rat |
Tao Tan, Bao-Liang Zhang, Xin Tia. [Chronic effects of oligomeric Aβ(1-42) on hippocampal synaptic plasticity in vivo]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 3. 2013-02-21. PMID:21681340. |
to investigate the variations of paired-pulse facilitation (ppf) and range of synaptic plasticity, field potentials were recorded in the dg of the dorsal hippocampus by stimulating the perforant path (pp). |
2013-02-21 |
2023-08-12 |
rat |
Helen E Scharfman, Catherine E Myer. Hilar mossy cells of the dentate gyrus: a historical perspective. Frontiers in neural circuits. vol 6. 2013-02-20. PMID:23420672. |
the circuitry of the dentate gyrus (dg) of the hippocampus is unique compared to other hippocampal subfields because there are two glutamatergic principal cells instead of one: granule cells, which are the vast majority of the cells in the dg, and the so-called "mossy cells." |
2013-02-20 |
2023-08-12 |
Not clear |
A Sah, C Schmuckermair, S B Sartori, S Gaburro, M Kandasamy, R Irschick, L Klimaschewski, R Landgraf, L Aigner, N Singewal. Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior. Translational psychiatry. vol 2. 2013-02-19. PMID:23047242. |
overall, these data suggest that ad-like effects in a psychopathological mouse model are commonly associated with modulation of dg hypoactivity but not neurogenesis, suggesting normalization of hippocampal hypoactivity as a neurobiological marker indicating successful remission. |
2013-02-19 |
2023-08-12 |
mouse |
Noriaki Ohkawa, Yoshito Saitoh, Eri Tokunaga, Itsuko Nihonmatsu, Fumiko Ozawa, Akiko Murayama, Fumi Shibata, Toshio Kitamura, Kaoru Inokuch. Spine formation pattern of adult-born neurons is differentially modulated by the induction timing and location of hippocampal plasticity. PloS one. vol 7. issue 9. 2013-02-15. PMID:23024813. |
in the adult hippocampus dentate gyrus (dg), newly born neurons are functionally integrated into existing circuits and play important roles in hippocampus-dependent memory. |
2013-02-15 |
2023-08-12 |
Not clear |
Geoffrey A Kerchner, Gayle K Deutsch, Michael Zeineh, Robert F Dougherty, Manojkumar Saranathan, Brian K Rut. Hippocampal CA1 apical neuropil atrophy and memory performance in Alzheimer's disease. NeuroImage. vol 63. issue 1. 2013-01-29. PMID:22766164. |
we scanned nine patients, using an oblique coronal t2-weighted sequence through the hippocampal body with an in-plane resolution of 220 μm, allowing direct visual identification of subfields - dentate gyrus (dg)/ca3, ca2, ca1, and erc - and hippocampal strata - srlm and stratum pyramidale (sp). |
2013-01-29 |
2023-08-12 |
Not clear |
R Hanaya, H Hosoyama, S Sugata, M Tokudome, H Hirano, H Tokimura, K Kurisu, T Serikawa, M Sasa, K Arit. Low distribution of synaptic vesicle protein 2A and synaptotagimin-1 in the cerebral cortex and hippocampus of spontaneously epileptic rats exhibiting both tonic convulsion and absence seizure. Neuroscience. vol 221. 2013-01-23. PMID:22766234. |
low and diffuse sv2a distribution portrayed in the cerebral cortex and hippocampus of sers was significantly less than that of all cerebral lobes and inner molecular layer (iml) of the dentate gyrus (dg) of wistar rats. |
2013-01-23 |
2023-08-12 |
rat |
A Wisłowska-Stanek, M Lehner, A Skórzewska, P Maciejak, J Szyndler, D Turzyńska, A Sobolewska, A Płaźni. Corticosterone attenuates conditioned fear responses and potentiates the expression of GABA-A receptor alpha-2 subunits in the brain structures of rats selected for high anxiety. Behavioural brain research. vol 235. issue 1. 2013-01-23. PMID:22820237. |
the behavioural effect of fear was accompanied by the increased expression of alpha-2 subunits in the basolateral amygdala (bla) and the dentate gyrus of the hippocampus (dg) of the hr group. |
2013-01-23 |
2023-08-12 |
rat |
Faviola Alcántara-González, Claudia Rebeca Mendoza-Perez, Néstor Zaragoza, Ismael Juarez, Luis Enrique Arroyo-García, Citlalli Gamboa, Fidel De La Cruz, Sergio Zamudio, Fernando Garcia-Dolores, Gonzalo Flore. Combined administration of cerebrolysin and donepezil induces plastic changes in prefrontal cortex in aged mice. Synapse (New York, N.Y.). vol 66. issue 11. 2013-01-09. PMID:22826038. |
the cbl or dnp treatment modified the dendritic morphology of neurons from prefrontal cortex (pfc), dorsal hippocampus (dh), dentate gyrus (dg), and the shell of nucleus accumbens (nacc). |
2013-01-09 |
2023-08-12 |
mouse |
Bingzhong Xu, Rong Yang, Fei Chang, Lei Chen, Guiqing Xie, Masahiro Sokabe, Ling Che. Neurosteroid PREGS protects neurite growth and survival of newborn neurons in the hippocampal dentate gyrus of APPswe/PS1dE9 mice. Current Alzheimer research. vol 9. issue 3. 2012-12-21. PMID:22272612. |
neurosteroids pregnenolone-sulfate (pregs) and dehydroepiandrosterone (dhea) have been shown to enhance neurogenesis in the hippocampal dentate gyrus (dg) of adult rodents. |
2012-12-21 |
2023-08-12 |
mouse |
Sofia Baptista, Ana Rita Bento, Joana Gonçalves, Liliana Bernardino, Teresa Summavielle, Andrea Lobo, Carlos Fontes-Ribeiro, João O Malva, Fabienne Agasse, Ana P Silv. Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22381583. |
taken together, meth negatively affects dg cell viability and neurogenesis, and npy is revealed to be a promising protective tool against the deleterious effects of meth on hippocampal neurogenesis. |
2012-12-20 |
2023-08-12 |
mouse |
Laura K Fonken, Emily Kitsmiller, Laura Smale, Randy J Nelso. Dim nighttime light impairs cognition and provokes depressive-like responses in a diurnal rodent. Journal of biological rhythms. vol 27. issue 4. 2012-12-17. PMID:22855576. |
following 3 weeks of exposure to standard light/dark (ld; 14:10 light [~150 lux] /dark [0 lux]) or dim light at night (dlan; 14:10 light [~150 lux] /dim [5 lux]), rats underwent behavioral testing, and hippocampal neurons within ca1, ca3, and the dentate gyrus (dg) were examined. |
2012-12-17 |
2023-08-12 |
rat |
Min-Kyoung Park, Seolhwa Kim, Uhee Jung, Insub Kim, Jin Kyu Kim, Changhyun Ro. Effect of acute and fractionated irradiation on hippocampal neurogenesis. Molecules (Basel, Switzerland). vol 17. issue 8. 2012-12-11. PMID:22874790. |
doublecortin (dcx) immunohistochemistry was used to measure changes of neurogenesis in the subgranular zone (sgz) of the hippocampal dentate gyrus (dg). |
2012-12-11 |
2023-08-12 |
mouse |
Sandra Hofer, Vincent Magloire, Jürg Streit, Stephen L Lei. Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis. Stem cells (Dayton, Ohio). vol 30. issue 6. 2012-11-29. PMID:22489030. |
autopsy studies in patients dying from bm show characteristic apoptotic brain injury to the stem cell niche in the subgranular zone of the hippocampal dentate gyrus (dg), and this form of brain damage is associated with learning and memory deficits in experimental bm. |
2012-11-29 |
2023-08-12 |
rat |
Sandra Hofer, Vincent Magloire, Jürg Streit, Stephen L Lei. Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis. Stem cells (Dayton, Ohio). vol 30. issue 6. 2012-11-29. PMID:22489030. |
green fluorescent protein (gfp)-expressing npcs were grafted into the dg of organotypic hippocampal slice cultures injured by challenge with live streptococcus pneumoniae. |
2012-11-29 |
2023-08-12 |
rat |
Sandra Hofer, Vincent Magloire, Jürg Streit, Stephen L Lei. Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis. Stem cells (Dayton, Ohio). vol 30. issue 6. 2012-11-29. PMID:22489030. |
seven days after engraftment, npcs had migrated from the site of injection into the injured granular layer of the dg and electro-functionally integrated into the hippocampal network. |
2012-11-29 |
2023-08-12 |
rat |
Sandra Hofer, Vincent Magloire, Jürg Streit, Stephen L Lei. Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis. Stem cells (Dayton, Ohio). vol 30. issue 6. 2012-11-29. PMID:22489030. |
in vivo, gfp-expressing npcs migrated within 1 week from the injection site in the hilus region to the injured granular layer of the hippocampal dg and showed neuronal differentiation at 2 and 4 weeks after transplantation. |
2012-11-29 |
2023-08-12 |
rat |