| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Li Zhu, Hai-Shui Shi, Shen-Jun Wang, Chun-Mei Xu, Wen-Gao Jiang, Xi Wang, Ping Wu, Qian-Qian Li, Zeng-Bo Ding, Lin L. Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behaviour in rats. The international journal of neuropsychopharmacology. vol 15. issue 6. 2012-10-19. PMID:21682945. |
inhibition of cdk5 in dg but not in the cornu ammonis 1 (ca1) or ca3 hippocampal subregions inhibited the development of depressive-like symptoms. |
2012-10-19 |
2023-08-12 |
rat |
| Miho Matsumata, Nobuyuki Sakayori, Motoko Maekawa, Yuji Owada, Takeo Yoshikawa, Noriko Osum. The effects of Fabp7 and Fabp5 on postnatal hippocampal neurogenesis in the mouse. Stem cells (Dayton, Ohio). vol 30. issue 7. 2012-10-19. PMID:22581784. |
new neurons are continually produced after birth from neural stem/progenitor cells (nscs/npcs) in the hippocampal dentate gyrus (dg). |
2012-10-19 |
2023-08-12 |
mouse |
| Tomohiko Iwano, Aki Masuda, Hiroshi Kiyonari, Hideki Enomoto, Fumio Matsuzak. Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus. Development (Cambridge, England). vol 139. issue 16. 2012-10-16. PMID:22791897. |
the brain is composed of diverse types of neurons that fulfill distinct roles in neuronal circuits, as manifested by the hippocampus, where pyramidal neurons and granule cells constitute functionally distinct domains: cornu ammonis (ca) and dentate gyrus (dg), respectively. |
2012-10-16 |
2023-08-12 |
mouse |
| Lin Chen, Shan Gong, Li-Dong Shan, Wei-Ping Xu, Yue-Jin Zhang, Shi-Yu Guo, Tadashi Hisamitsu, Qi-Zhang Yin, Xing-Hong Jian. Effects of exercise on neurogenesis in the dentate gyrus and ability of learning and memory after hippocampus lesion in adult rats. Neuroscience bulletin. vol 22. issue 1. 2012-10-02. PMID:17684532. |
results hippocampus lesion could increase the number of brdu-labeled dg cells, moderately running after lesion could further enhance the number of brdu-labeled cells and decrease the error number (en) in y maze test, while neither lightly running, nor heavily running had such effects. |
2012-10-02 |
2023-08-12 |
rat |
| Wei Sheng, Hui-Wang Hang, Di-Yun Rua. In vivo microdialysis study of the relationship between lead-induced impairment of learning and neurotransmitter changes in the hippocampus. Environmental toxicology and pharmacology. vol 20. issue 1. 2012-10-02. PMID:21783594. |
in this study, the extracellular levels of amino acids in the dentate gyrus (dg) of the hippocampus of early postnatal rats exposed to lead were measured by in vivo microdialysis, before and after 50 days of training. |
2012-10-02 |
2023-08-12 |
rat |
| Marijn Schouten, M Renate Buijink, Paul J Lucassen, Carlos P Fitzsimon. New Neurons in Aging Brains: Molecular Control by Small Non-Coding RNAs. Frontiers in neuroscience. vol 6. 2012-10-02. PMID:22363255. |
it is largely confined to two main regions: the subventricular zone of the lateral ventricle, and the subgranular zone of the dentate gyrus (dg), in the hippocampus. |
2012-10-02 |
2023-08-12 |
Not clear |
| Marijn Schouten, M Renate Buijink, Paul J Lucassen, Carlos P Fitzsimon. New Neurons in Aging Brains: Molecular Control by Small Non-Coding RNAs. Frontiers in neuroscience. vol 6. 2012-10-02. PMID:22363255. |
with age, the function of the hippocampus and particularly the dg is impaired. |
2012-10-02 |
2023-08-12 |
Not clear |
| Zexuan Li, Gal Richter-Levi. Stimulus intensity-dependent modulations of hippocampal long-term potentiation by basolateral amygdala priming. Frontiers in cellular neuroscience. vol 6. 2012-10-02. PMID:22586371. |
in the present study we assessed the effects of two stronger levels of bla priming stimulation (1 v or 2 v, 100 μs pulse duration) on ltp induction in hippocampal dg and ca1, in anesthetized rats. |
2012-10-02 |
2023-08-12 |
rat |
| Zexuan Li, Gal Richter-Levi. Stimulus intensity-dependent modulations of hippocampal long-term potentiation by basolateral amygdala priming. Frontiers in cellular neuroscience. vol 6. 2012-10-02. PMID:22586371. |
results show that 1v-bla priming stimulation enhanced but 2v-bla priming stimulation impaired dg ltp; however, both levels of bla priming stimulation impaired ca1 ltp, suggesting that modulation of hippocampal synaptic plasticity by amygdala is dependent on the degree of amygdala activation. |
2012-10-02 |
2023-08-12 |
rat |
| Flávio Freitas Barbosa, Isabella Maria de Oliveira Pontes, Sidarta Ribeiro, Alessandra Mussi Ribeiro, Regina Helena Silv. Differential roles of the dorsal hippocampal regions in the acquisition of spatial and temporal aspects of episodic-like memory. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22546523. |
computational models suggest that the dentate gyrus (dg) and the ca3 hippocampal subregions are involved in pattern separation and the rapid acquisition of episodes, while ca1 is involved in the formation of a temporal context. |
2012-09-27 |
2023-08-12 |
rat |
| Desiree Antequera, Aitziber Portero, Marta Bolos, Gorka Orive, Rosa M Rm A Hernández, José Luis Pedraz, Eva Carr. Encapsulated VEGF-secreting cells enhance proliferation of neuronal progenitors in the hippocampus of AβPP/Ps1 mice. Journal of Alzheimer's disease : JAD. vol 29. issue 1. 2012-09-21. PMID:22232015. |
stereological counting of 5-bromodeoxyuridine positive cells revealed that encapsulated vegf secreting cells significantly enhanced cellular proliferation in the hippocampal dentate gyrus (dg). |
2012-09-21 |
2023-08-12 |
mouse |
| Alexander M Kleschevnikov, Pavel V Belichenko, Mehrdad Faizi, Lucia F Jacobs, Khin Htun, Mehrdad Shamloo, William C Moble. Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764230. |
in hippocampal slices, treatment with the gaba(b) receptor antagonists cgp55845 or cgp52432 enhanced long-term potentiation (ltp) in the ts65dn dg. |
2012-09-18 |
2023-08-12 |
mouse |
| Sabrina K Segal, Shauna M Stark, David Kattan, Craig E Stark, Michael A Yass. Norepinephrine-mediated emotional arousal facilitates subsequent pattern separation. Neurobiology of learning and memory. vol 97. issue 4. 2012-09-17. PMID:22498686. |
pattern separation, the process by which similar experiences can be stored as distinct memories, has been ascribed to the dentate gyrus (dg) of the hippocampus. |
2012-09-17 |
2023-08-12 |
human |
| R H S Westerink, J P Beekwilder, W J Wadma. Differential alterations of synaptic plasticity in dentate gyrus and CA1 hippocampal area of Calbindin-D28K knockout mice. Brain research. vol 1450. 2012-09-14. PMID:22405690. |
in the present study, the role of cb in synaptic transmission and plasticity was further investigated using extracellular recordings of synaptic activity in cell- and dendritic layers of dentate gyrus (dg) and ca1 area in hippocampal slices from wild-type, heterozygous and homozygous cb knockout mice. |
2012-09-14 |
2023-08-12 |
mouse |
| R H S Westerink, J P Beekwilder, W J Wadma. Differential alterations of synaptic plasticity in dentate gyrus and CA1 hippocampal area of Calbindin-D28K knockout mice. Brain research. vol 1450. 2012-09-14. PMID:22405690. |
the results demonstrate a consistent failure to maintain long-term potentiation (ltp) in hippocampal dg and ca1 area of knockout mice. |
2012-09-14 |
2023-08-12 |
mouse |
| R H S Westerink, J P Beekwilder, W J Wadma. Differential alterations of synaptic plasticity in dentate gyrus and CA1 hippocampal area of Calbindin-D28K knockout mice. Brain research. vol 1450. 2012-09-14. PMID:22405690. |
the combined results demonstrate that the absence of cb results in an impairment of ltp maintenance in both hippocampal dg and ca1 area, whereas paired-pulse facilitation and cellular excitability in ca1 area are differentially affected. |
2012-09-14 |
2023-08-12 |
mouse |
| R H S Westerink, J P Beekwilder, W J Wadma. Differential alterations of synaptic plasticity in dentate gyrus and CA1 hippocampal area of Calbindin-D28K knockout mice. Brain research. vol 1450. 2012-09-14. PMID:22405690. |
these results support the role of cb as a critical determinant for several forms of synaptic plasticity in hippocampal dg and ca1 area. |
2012-09-14 |
2023-08-12 |
mouse |
| Dae Young Yoo, Woosuk Kim, Ki-Yeon Yoo, Choong Hyun Lee, Jung Hoon Choi, Yeo Sung Yoon, Dong-Woo Kim, Moo-Ho Won, In Koo Hwan. Grape seed extract enhances neurogenesis in the hippocampal dentate gyrus in C57BL/6 mice. Phytotherapy research : PTR. vol 25. issue 5. 2012-09-12. PMID:21043032. |
the effects of grape seed extract (gse), a major source of phenolic compounds, were examined on cell proliferation, neuroblast differentiation and integration into granule cells in the hippocampal dentate gyrus (dg) of middle-aged (12 month-old) mice using ki67, doublecortin (dcx) immunohistochemistry and 5'-bromo-2-deoxyguanosine (brdu)/calbindin d-28k (cb) double immunofluorescence study, respectively. |
2012-09-12 |
2023-08-12 |
mouse |
| Dae Young Yoo, Woosuk Kim, Ki-Yeon Yoo, Choong Hyun Lee, Jung Hoon Choi, Yeo Sung Yoon, Dong-Woo Kim, Moo-Ho Won, In Koo Hwan. Grape seed extract enhances neurogenesis in the hippocampal dentate gyrus in C57BL/6 mice. Phytotherapy research : PTR. vol 25. issue 5. 2012-09-12. PMID:21043032. |
these results suggest that gse significantly increases cell proliferation, neuroblast differentiation and integration into granule cells in the dg, and the consumption of gse enhances the plasticity of hippocampus in middle-aged mice. |
2012-09-12 |
2023-08-12 |
mouse |
| Xiaoxing Ma, Mazen J Hamadeh, Brain R Christie, Jane A Foster, Mark A Tarnopolsk. Impact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosis. PloS one. vol 7. issue 4. 2012-09-07. PMID:22558322. |
hippocampal neurogenesis in the subgranular zone (sgz) of dentate gyrus (dg) occurs throughout life and is regulated by pathological and physiological processes. |
2012-09-07 |
2023-08-12 |
mouse |