Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ting Lian, Shu-Cheng A. [Antidepressant effect of microinjection of neuropeptide Y into the hippocampus is mediated by decreased expression of nitric oxide synthase]. Sheng li xue bao : [Acta physiologica Sinica]. vol 62. issue 3. 2015-04-21. PMID:20571741. |
moreover, the expression of npy significantly decreased (p<0.01), while the expressions of nnos and inos increased obviously in the hippocampal dentate gyrus (dg) and ca3 regions (p<0.01). |
2015-04-21 |
2023-08-12 |
rat |
Ting Lian, Shu-Cheng A. [Antidepressant effect of microinjection of neuropeptide Y into the hippocampus is mediated by decreased expression of nitric oxide synthase]. Sheng li xue bao : [Acta physiologica Sinica]. vol 62. issue 3. 2015-04-21. PMID:20571741. |
intrahippocampal microinjections of npy prevented the depression-like behavioral changes induced by cums and decreased the expressions of nnos and inos in the hippocampal dg and ca3 regions (p<0.01). |
2015-04-21 |
2023-08-12 |
rat |
Meng Na, Yanshu Liu, Chen Shi, Wenpeng Gao, Haitao Ge, Yu Wang, Haiyang Wang, Yu Long, Hong Shen, Changbin Shi, Zhiguo Li. Prognostic value of CA4/DG volumetry with 3T magnetic resonance imaging on postoperative outcome of epilepsy patients with dentate gyrus pathology. Epilepsy research. vol 108. issue 8. 2015-04-20. PMID:25085233. |
pathological hallmarks in hippocampal dentate gyrus (dg), including granule cell loss (gcl) and granule cell dispersion (gcd), are known to be closely related to the status epilepticus and spontaneous seizure. |
2015-04-20 |
2023-08-13 |
Not clear |
Christian K Tamnes, Kristine B Walhovd, Andreas Engvig, Håkon Grydeland, Stine K Krogsrud, Ylva Østby, Dominic Holland, Anders M Dale, Anders M Fjel. Regional hippocampal volumes and development predict learning and memory. Developmental neuroscience. vol 36. issue 3-4. 2015-04-17. PMID:24902771. |
hippocampal subfield volumes were estimated by the use of automated segmentation of 7 subfields, including the cornu ammonis (ca) sectors and the dentate gyrus (dg), while longitudinal subfield volumetric change was quantified using a nonlinear registration procedure. |
2015-04-17 |
2023-08-13 |
human |
Margaret A Broadwater, Wen Liu, Fulton T Crews, Linda P Spea. Persistent loss of hippocampal neurogenesis and increased cell death following adolescent, but not adult, chronic ethanol exposure. Developmental neuroscience. vol 36. issue 3-4. 2015-04-17. PMID:24993092. |
given that disruption in adult neurogenesis has been reported to impair performance on tasks thought to be hippocampally related, we used immunohistochemistry to assess levels of doublecortin (dcx), an endogenous marker of immature neurons, in the dentate gyrus (dg) of the hippocampus 3-4 weeks after adolescent (postnatal day, pd28-48) or adult (pd70-90) intermittent ethanol exposure to 4 g/kg ethanol administered intragastrically. |
2015-04-17 |
2023-08-13 |
Not clear |
Matteo Bergami, Giacomo Masserdotti, Silvio G Temprana, Elisa Motori, Therese M Eriksson, Jana Göbel, Sung Min Yang, Karl-Klaus Conzelmann, Alejandro F Schinder, Magdalena Götz, Benedikt Berninge. A critical period for experience-dependent remodeling of adult-born neuron connectivity. Neuron. vol 85. issue 4. 2015-04-14. PMID:25661179. |
neurogenesis in the dentate gyrus (dg) of the adult hippocampus is a process regulated by experience. |
2015-04-14 |
2023-08-13 |
Not clear |
Faramarz Faghihi, Ahmed A Moustaf. A computational model of pattern separation efficiency in the dentate gyrus with implications in schizophrenia. Frontiers in systems neuroscience. vol 9. 2015-04-10. PMID:25859189. |
information processing in the hippocampus begins by transferring spiking activity of the entorhinal cortex (ec) into the dentate gyrus (dg). |
2015-04-10 |
2023-08-13 |
Not clear |
Faramarz Faghihi, Ahmed A Moustaf. A computational model of pattern separation efficiency in the dentate gyrus with implications in schizophrenia. Frontiers in systems neuroscience. vol 9. 2015-04-10. PMID:25859189. |
activity pattern in the ec is separated by the dg such that it plays an important role in hippocampal functions including memory. |
2015-04-10 |
2023-08-13 |
Not clear |
Anna-Lena Hillje, Elisabeth Beckmann, Maria A S Pavlou, Christian Jaeger, Maria P Pacheco, Thomas Sauter, Jens C Schwamborn, Lars Lewejohan. The neural stem cell fate determinant TRIM32 regulates complex behavioral traits. Frontiers in cellular neuroscience. vol 9. 2015-04-08. PMID:25852471. |
in mammals, new neurons are generated throughout the entire lifespan in two restricted areas of the brain, the dentate gyrus (dg) of the hippocampus and the subventricular zone (svz)-olfactory bulb (ob) system. |
2015-04-08 |
2023-08-13 |
mouse |
C A Bostrom, N-M Majaess, K Morch, E White, B D Eadie, B R Christi. Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 1. 2015-04-06. PMID:23968838. |
we report that a loss of fmrp leads to impairments in n-methyl-d-aspartate receptor (nmdar)-dependent synaptic plasticity in the dentate gyrus (dg), but not in the cornu ammonis area 1 (ca1) subregion of the hippocampus of adult mice. |
2015-04-06 |
2023-08-12 |
mouse |
Erlend Bøen, Lars T Westlye, Torbjørn Elvsåshagen, Benjamin Hummelen, Per K Hol, Birgitte Boye, Stein Andersson, Sigmund Karterud, Ulrik F Mal. Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder. Journal of psychiatry & neuroscience : JPN. vol 39. issue 2. 2015-04-02. PMID:24309162. |
based on the putative role of stressful life events as vulnerability factors for bpd, we hypothesized that patients with bpd would exhibit reduced volumes for the stress-sensitive dentate gyrus (dg) and the cornu ammonis (ca) 3 subfields volumes, and that these volumes would be associated with traumatic childhood experiences. |
2015-04-02 |
2023-08-12 |
human |
Gang Li, Ting Liu, Xiangqian Kong, Lei Wang, Xing Ji. Hippocampal glycogen synthase kinase 3β is critical for the antidepressant effect of cyclin-dependent kinase 5 inhibitor in rats. Journal of molecular neuroscience : MN. vol 54. issue 1. 2015-04-01. PMID:24563226. |
evidence of previous study showed that chronic inhibition of cdk5 in hippocampal dentate gyrus (dg) blocked the development of depressive-like symptoms, suggesting that cdk5 plays a role in development of depression. |
2015-04-01 |
2023-08-12 |
rat |
Sloka S Iyengar, John J LaFrancois, Daniel Friedman, Liam J Drew, Christine A Denny, Nesha S Burghardt, Melody V Wu, Jenny Hsieh, René Hen, Helen E Scharfma. Suppression of adult neurogenesis increases the acute effects of kainic acid. Experimental neurology. vol 264. 2015-03-30. PMID:25476494. |
adult neurogenesis, the generation of new neurons in the adult brain, occurs in the hippocampal dentate gyrus (dg) and the olfactory bulb (ob) of all mammals, but the functions of these new neurons are not entirely clear. |
2015-03-30 |
2023-08-13 |
mouse |
R Kohen, A Dobra, J H Tracy, E Hauge. Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness. Translational psychiatry. vol 4. 2015-03-06. PMID:24594777. |
we investigated the transcriptome of dentate gyrus (dg) granule cells in postmortem human hippocampus in 79 subjects with mental illness (schizophrenia, bipolar disorder, major depression) and nonpsychiatric controls. |
2015-03-06 |
2023-08-12 |
human |
Quan-Guang Zhang, Ruimin Wang, Hui Tang, Yan Dong, Alice Chan, Gangadhara Reddy Sareddy, Ratna K Vadlamudi, Darrell W Bran. Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus. Molecular and cellular endocrinology. vol 389. issue 1-2. 2015-03-02. PMID:24508637. |
immunohistochemistry (ihc) revealed that the hippocampal regions ca1, ca3 and dentate gyrus (dg) exhibited high levels of immunoreactive aromatase staining, with aromatase being co-localized primarily in neurons in non-ischemic animals. |
2015-03-02 |
2023-08-12 |
rat |
Jianlong Zhuang, Qiulan Wei, Zhaohua Lin, Changwen Zho. Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain. Gene. vol 555. issue 2. 2015-02-17. PMID:25445276. |
we found that conditional disruption of adam10 resulted in a prominent decrease in the number of proliferating neuronal progenitor cells in the subgranular zone (sgz), and a significant increase in the number of adult-generated postmitotic neurons in the hippocampal dentate gyrus (dg) due to premature neuronal differentiation. |
2015-02-17 |
2023-08-13 |
mouse |
Jianlong Zhuang, Qiulan Wei, Zhaohua Lin, Changwen Zho. Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain. Gene. vol 555. issue 2. 2015-02-17. PMID:25445276. |
moreover, the mutant mice also displayed an age-dependent reduction in the number of granule neurons in the hippocampal dg. |
2015-02-17 |
2023-08-13 |
mouse |
Dustin R Masser, Georgina V Bixler, Robert M Brucklacher, Han Yan, Cory B Giles, Jonathan D Wren, William E Sonntag, Willard M Freema. Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 69. issue 11. 2015-02-13. PMID:24994846. |
hippocampal subregions (ca1, ca3, and dg) have been previously reported to express both common and specific morphological, functional, and gene/protein alterations with aging and cognitive decline. |
2015-02-13 |
2023-08-13 |
rat |
Melody V Wu, Jul Lea Shamy, Gillinder Bedi, Chien-Wen J Choi, Melanie M Wall, Victoria Arango, Maura Boldrini, Richard W Foltin, René He. Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24518288. |
to better bridge the gap between rodent and human physiology, we examined the numbers of proliferating neural precursors and immature cells in the hippocampal dentate gyrus (dg) as well as in vivo magnetic resonance imaging (mri)-estimated whole hippocampal volume in eight socially dominant- or subordinate-like (sl) baboons administered the antidepressant fluoxetine or vehicle. |
2015-02-12 |
2023-08-12 |
human |
Melody V Wu, Jul Lea Shamy, Gillinder Bedi, Chien-Wen J Choi, Melanie M Wall, Victoria Arango, Maura Boldrini, Richard W Foltin, René He. Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24518288. |
these findings are the first to indicate that adult neurogenesis in the baboon hippocampal dg may be functionally relevant in the context of social stress and mechanisms of antidepressant action. |
2015-02-12 |
2023-08-12 |
human |