| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chang-Qi Li, Yan-Wei Luo, Fang-Fang Bi, Tao-Tao Cui, Ling Song, Wen-Yu Cao, Jian-Yi Zhang, Fang Li, Jun-Mei Xu, Wei Hao, Xiao-Wei Xing, Fiona H Zhou, Xin-Fu Zhou, Ru-Ping Da. Development of anxiety-like behavior via hippocampal IGF-2 signaling in the offspring of parental morphine exposure: effect of enriched environment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24889368. |
we report here that morphine exposure of adult male and female rats resulted in anxiety-like behavior and dendritic retraction in the dentate gyrus (dg) region of the hippocampus in their adult offspring. |
2015-07-10 |
2023-08-13 |
rat |
| Jing Wang, Allison Cheng, Chandramohan Wakade, Robert K Y. Ganglioside GD3 is required for neurogenesis and long-term maintenance of neural stem cells in the postnatal mouse brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 41. 2015-07-08. PMID:25297105. |
gd3s-ko mice with deficiency in gd3 and the downstream b-series gangliosides showed a progressive loss of nscs both at the svz and the dg of the hippocampus. |
2015-07-08 |
2023-08-13 |
mouse |
| Michael J Darcy, Stéphanie Trouche, Shan-Xue Jin, Larry A Fei. Ras-GRF2 mediates long-term potentiation, survival, and response to an enriched environment of newborn neurons in the hippocampus. Hippocampus. vol 24. issue 11. 2015-07-07. PMID:24894950. |
hippocampal adult neurogenesis contributes to key functions of the dentate gyrus (dg), including contextual discrimination. |
2015-07-07 |
2023-08-13 |
mouse |
| Andrés P Varani, Lirane Moutinho Machado, Graciela N Baleri. Baclofen prevented the changes in c-Fos and brain-derived neutrophic factor expressions during mecamylamine-precipitated nicotine withdrawal in mice. Synapse (New York, N.Y.). vol 68. issue 11. 2015-06-26. PMID:25042794. |
c-fos expression decreased in the dentate gyrus of the hippocampus (dg) and the bed nucleus of the stria terminalis (bst), and increased in the habenular (hb), accumbens shell (acbsh) nuclei during nic withdrawal. |
2015-06-26 |
2023-08-13 |
mouse |
| Miyeon Choi, Sung Eun Wang, Seung Yeon Ko, Hyo Jung Kang, Seung Yeun Chae, Seung Hoon Lee, Yong-Seok Kim, Ronald S Duman, Hyeon So. Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats. PloS one. vol 9. issue 10. 2015-06-25. PMID:25340772. |
we investigated the effects of adeno-associated viral expression of hgata-1 and hgata-2 (aav-hgata1 and aav-hgata2) in the dentate gyrus (dg) of the dorsal hippocampus on dendrite branching and spine number. |
2015-06-25 |
2023-08-13 |
human |
| Stine K Krogsrud, Christian K Tamnes, Anders M Fjell, Inge Amlien, Håkon Grydeland, Unni Sulutvedt, Paulina Due-Tønnessen, Atle Bjørnerud, Anne E Sølsnes, Asta K Håberg, Jon Skrane, Kristine B Walhov. Development of hippocampal subfield volumes from 4 to 22 years. Human brain mapping. vol 35. issue 11. 2015-06-15. PMID:24976170. |
using cross-sectional 1.5 t magnetic resonance imaging data from 244 healthy participants aged 4-22 years, we performed automated hippocampal segmentation of seven subfield volumes; cornu ammonis (ca) 1, ca2/3, ca4/dentate gyrus (dg), presubiculum, subiculum, fimbria, and hippocampal fissure. |
2015-06-15 |
2023-08-13 |
human |
| Monika Bijata, Jakub Wlodarczyk, Izabela Figie. Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro. Frontiers in cellular neuroscience. vol 9. 2015-06-15. PMID:26074769. |
using a lentiviral vector to deliver short-hairpin rna (shrna) that specifically silences dg in cultured hippocampal neurons, we found that dg knockdown exerted an inhibitory effect on dendritic tree growth and arborization. |
2015-06-15 |
2023-08-13 |
Not clear |
| Matthew A Olude, Oluwaseun A Mustapha, Oluwatunde A Aderounmu, James O Olopade, Amadi O Ihunw. Astrocyte morphology, heterogeneity, and density in the developing African giant rat (Cricetomys gambianus). Frontiers in neuroanatomy. vol 9. 2015-06-15. PMID:26074782. |
astrocyte heterogeneity in juvenile and adult groups revealed eight subtypes to include fibrous astrocytes chiefly in the corpus callosum and brain stem, protoplasmic astrocytes in the cortex and dentate gyrus (dg); radial glia were found along the olfactory bulb (ob) and subventricular zone (svz); velate astrocytes were mainly found in the cerebellum and hippocampus; marginal astrocytes close to the pia mater; bergmann glia in the molecular layer of the cerebellum; perivascular and periventricular astrocytes in the cortex and third ventricle, respectively. |
2015-06-15 |
2023-08-13 |
rat |
| Hirofumi Hayakawa, Toshikazu Samura, Tadanobu Chuyo Kamijo, Yutaka Sakai, Takeshi Aihar. Spatial information enhanced by non-spatial information in hippocampal granule cells. Cognitive neurodynamics. vol 9. issue 1. 2015-06-08. PMID:26052358. |
the dentate gyrus (dg) in the hippocampus receives two types of information from the lateral and medial entorhinal cortices. |
2015-06-08 |
2023-08-13 |
rat |
| Zhen Zhang, Rong Yan, Qi Zhang, Jia Li, Xiaokui Kang, Haining Wang, Linchun Huan, Lin Zhang, Fan Li, Shuyuan Yang, Jianning Zhang, Xinliang Ren, Xinyu Yan. Hes1, a Notch signaling downstream target, regulates adult hippocampal neurogenesis following traumatic brain injury. Brain research. vol 1583. 2015-06-05. PMID:25084035. |
here, we investigate the role of hes1 in regulating neurogenesis in the dg of the adult hippocampus after tbi by up- or downregulating hes1 expression. |
2015-06-05 |
2023-08-13 |
mouse |
| Zhen Zhang, Rong Yan, Qi Zhang, Jia Li, Xiaokui Kang, Haining Wang, Linchun Huan, Lin Zhang, Fan Li, Shuyuan Yang, Jianning Zhang, Xinliang Ren, Xinyu Yan. Hes1, a Notch signaling downstream target, regulates adult hippocampal neurogenesis following traumatic brain injury. Brain research. vol 1583. 2015-06-05. PMID:25084035. |
we show that enhancing hes1 inhibits the proliferation and differentiation of neural precursor cells (npcs) in the dg of the hippocampus soon after tbi. |
2015-06-05 |
2023-08-13 |
mouse |
| Francele Valente Piazza, Ethiane Segabinazi, Lígia Aline Centenaro, Patrícia Severo do Nascimento, Matilde Achaval, Simone Marcuzz. Enriched environment induces beneficial effects on memory deficits and microglial activation in the hippocampus of type 1 diabetic rats. Metabolic brain disease. vol 29. issue 1. 2015-06-02. PMID:24318482. |
thus, our objective was to investigate the influence of the ee on memory deficits, locomotion, corticosterone levels, synaptophysin (syp) protein immunoreactivity, cell survival and microglial activation in the dentate gyrus (dg) of t1dm rat hippocampus. |
2015-06-02 |
2023-08-12 |
rat |
| Maryann Obiorah, Elizabeth McCandlish, Brian Buckley, Emanuel DiCicco-Bloo. Hippocampal developmental vulnerability to methylmercury extends into prepubescence. Frontiers in neuroscience. vol 9. 2015-06-01. PMID:26029035. |
we previously showed that a single low exposure (0.6 μg/gbw) that approaches human exposure reduced hippocampal neurogenesis in the dentate gyrus (dg) 24 h later, producing later proliferation and memory deficits in adolescence. |
2015-06-01 |
2023-08-13 |
human |
| Sandra A Acosta, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Paul R Sanberg, Juan Sanchez-Ramos, Shijie Song, Yuji Kaneko, Cesar V Borlonga. Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury. PloS one. vol 9. issue 3. 2015-05-29. PMID:24621603. |
results revealed that the rats exposed to tbi treated with saline exhibited widespread neuroinflammation, impaired endogenous neurogenesis in dg and svz, and severe hippocampal cell loss. |
2015-05-29 |
2023-08-12 |
human |
| Sandra A Acosta, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Paul R Sanberg, Juan Sanchez-Ramos, Shijie Song, Yuji Kaneko, Cesar V Borlonga. Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury. PloS one. vol 9. issue 3. 2015-05-29. PMID:24621603. |
g-csf monotherapy produced partial and short-lived benefits characterized by low levels of neuroinflammation in striatum, dg, svz, and corpus callosum and fornix, a modest neurogenesis, and a moderate reduction of hippocampal cells loss. |
2015-05-29 |
2023-08-12 |
human |
| Katherine E Davis, Sarah Fox, John Gig. Increased hippocampal excitability in the 3xTgAD mouse model for Alzheimer's disease in vivo. PloS one. vol 9. issue 3. 2015-05-29. PMID:24621690. |
here, we tested whether hippocampal synaptic dysfunction accompanies this cognitive deficit by probing dorsal ca1 and dg synaptic responses in anaesthetized, 4-6 month-old 3xtgad mice. |
2015-05-29 |
2023-08-12 |
mouse |
| Yuan Le, Shuli Liu, Mingchao Peng, Chang Tan, Qin Liao, Kaiming Duan, Wen Ouyang, Jianbin Ton. Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery. PloS one. vol 9. issue 9. 2015-05-28. PMID:25198176. |
we found that (1) in young adult rats, the memory was not significantly affected (p>0.05) 1d, 3d and 7d after partial hepatectomy, but was significantly impaired (p<0.001) in aged rats 1d and 3d post-surgery; (2) in young adult rats, the surgery did not significantly affect the densities of dendritic spines of neurons at ca1, dentate gyrus (dg) and cingulate cortex (p>0.05, respectively) 1d and 3d post-surgery, but the spine densities at ca1 and dg of aged rats were significant reduced 1d and 3d post-surgery (p<0.001, respectively), however this didn't happen at cingulate cortex (p>0.05); (3) in young adult rats, surgery didn't affect the activation of microglia and levels of tnf-α and il-1β at hippocampus (p>0.05), but significantly activated microglia and increased levels of tnf-α and il-1β at hippocampus of aged rats (p<0.05). |
2015-05-28 |
2023-08-13 |
rat |
| Libin Zhou, Zihong Lu, Lin Li, Lei Chen, Jianhua Qi, Ling Che. Pro-neurogenesis and anti-dementia properties of tetradecyl 2,3-dihydroxybenzoate through TrkA receptor-mediated signalling pathways. The international journal of neuropsychopharmacology. vol 17. issue 11. 2015-05-26. PMID:24787365. |
herein, we report that oral administration of abg001 for five days to adult male mice could dose-dependently enhance survival and neurite growth of newborn cells in hippocampal dentate gyrus (dg) without changes in cell proliferation and differentiation of progenitor cells. |
2015-05-26 |
2023-08-13 |
mouse |
| Julia Marschallinger, Monika Krampert, Sebastien Couillard-Despres, Rainer Heuchel, Ulrich Bogdahn, Ludwig Aigne. Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis. Experimental gerontology. vol 57. 2015-05-26. PMID:24862634. |
we recently reported that young (3 to 4months old) mice lacking exon 1 of the smad7 gene (s7Δex1 mice) show enhanced proliferation of neural stem and progenitor cells (npcs) in the hippocampal dentate gyrus (dg) and in the subventricular zone (svz) of the lateral ventricles. |
2015-05-26 |
2023-08-13 |
mouse |
| Valentina Corvino, Elisa Marchese, Maria Vittoria Podda, Wanda Lattanzi, Stefano Giannetti, Valentina Di Maria, Sara Cocco, Claudio Grassi, Fabrizio Michetti, Maria Concetta Gelos. The neurogenic effects of exogenous neuropeptide Y: early molecular events and long-lasting effects in the hippocampus of trimethyltin-treated rats. PloS one. vol 9. issue 2. 2015-05-22. PMID:24516629. |
as a functional correlate of the integration of new neurons into the hippocampal network, long-term potentiation recorded in dentate gyrus (dg) in the absence of gabaa receptor blockade was higher in the tmt+npy-treated group than in all other groups. |
2015-05-22 |
2023-08-12 |
rat |