| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Pósfai, C Cserép, P Hegedüs, E Szabadits, D M Otte, A Zimmer, M Watanabe, T F Freund, G Nyir. Synaptic and cellular changes induced by the schizophrenia susceptibility gene G72 are rescued by N-acetylcysteine treatment. Translational psychiatry. vol 6. 2017-11-21. PMID:27163208. |
transgenic mice carrying the entire gene locus express g72 mrna in dentate gyrus (dg) and entorhinal cortex, causing altered electrophysiological properties of their connections. |
2017-11-21 |
2023-08-13 |
mouse |
| Hongyu Pan, Dongpi Wang, Xiaoqin Zhang, Dongming Zhou, Heng Zhang, Qi Qian, Xiao He, Zhaoling Liu, Yunjin Liu, Tingting Zheng, Ling Zhang, Mingkai Wang, Binggui Su. Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein. Stem cell reports. vol 7. issue 4. 2017-11-21. PMID:27693425. |
here, we found that neurogenesis was impaired in the dentate gyrus (dg) of adult mice overexpressing wild-type happ (happ-i5) compared with controls. |
2017-11-21 |
2023-08-13 |
mouse |
| Courtney L Huff, Rachel L Morano, James P Herman, Bryan K Yamamoto, Gary A Gudelsk. MDMA decreases glutamic acid decarboxylase (GAD) 67-immunoreactive neurons in the hippocampus and increases seizure susceptibility: Role for glutamate. Neurotoxicology. vol 57. 2017-11-21. PMID:27773601. |
repeated exposure to mdma (3×10mg/kg, ip) resulted in a reduction of 37-58% of gad67-ir cells in the dentate gyrus (dg), ca1, and ca3 regions, as well as an increased susceptibility to kainic acid-induced seizures, both of which persisted for at least 30days following mdma treatment. |
2017-11-21 |
2023-08-13 |
rat |
| Hagit Sela, Hagit Cohen, Zeev Karpas, Yehuda Zeir. Distinctive hippocampal zinc distribution patterns following stress exposure in an animal model of PTSD. Metallomics : integrated biometal science. vol 9. issue 3. 2017-11-21. PMID:28252129. |
it has been found that zn distribution in the dentate gyrus (dg) sub-region in the hippocampus is clearly more widely spread for rats that belong to the extreme behavioral response (ebr) group as compared to the control group. |
2017-11-21 |
2023-08-13 |
human |
| B Cao, I C Passos, B Mwangi, H Amaral-Silva, J Tannous, M-J Wu, G B Zunta-Soares, J C Soare. Hippocampal subfield volumes in mood disorders. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28115740. |
however, the hippocampus is not a uniform structure and consists of several subfields, such as the cornu ammonis (ca) subfields ca1-4, the dentate gyrus (dg) including a granule cell layer (gcl) and a molecular layer (ml) that continuously crosses adjacent subiculum (sub) and ca fields. |
2017-11-16 |
2023-08-13 |
human |
| C Dioli, P Patrício, R Trindade, L G Pinto, J M Silva, M Morais, E Ferreiro, S Borges, A Mateus-Pinheiro, A J Rodrigues, N Sousa, J M Bessa, L Pinto, I Sotiropoulo. Tau-dependent suppression of adult neurogenesis in the stressed hippocampus. Molecular psychiatry. vol 22. issue 8. 2017-11-13. PMID:28555078. |
here, we analyzed the role of tau on stress-driven suppression of neurogenesis in the adult dentate gyrus (dg) using animals lacking tau (tau-knockout; tau-ko) and wild-type (wt) littermates. |
2017-11-13 |
2023-08-13 |
mouse |
| Ryan A Kirk, Sarah N Redmon, Raymond P Kesne. The ventral dentate gyrus mediates pattern separation for reward value. Behavioral neuroscience. vol 131. issue 1. 2017-11-10. PMID:28004952. |
rats with ventral dentate gyrus (dg) lesions, sham lesions, and controls were run in a runway for 20 pellets of food. |
2017-11-10 |
2023-08-13 |
rat |
| Luiz E C Santos, Antônio M Rodrigues, Mariana R Lopes, Victor D C Costa, Carla A Scorza, Fulvio A Scorza, Esper A Cavalheiro, Antônio-Carlos G Almeid. Long-term alcohol exposure elicits hippocampal nonsynaptic epileptiform activity changes associated with expression and functional changes in NKCC1, KCC2 co-transporters and Na Neuroscience. vol 340. 2017-11-07. PMID:27871891. |
long-term alcohol exposure elicits hippocampal nonsynaptic epileptiform activity changes associated with expression and functional changes in nkcc1, kcc2 co-transporters and na nonsynaptic mechanism changes, particularly the enhancement of nkcc1 expression in the dentate gyrus (dg) after 4weeks of ethanol consumption, motivate the present work, in which rats were submitted to a period of chronic consumption (12weeks). |
2017-11-07 |
2023-08-13 |
rat |
| Bo Young Choi, In Yeol Kim, Jin Hee Kim, Bo Eun Lee, Song Hee Lee, A Ra Kho, Min Sohn, Sang Won Su. Zinc plus cyclo-(His-Pro) promotes hippocampal neurogenesis in rats. Neuroscience. vol 339. 2017-11-06. PMID:27773743. |
it has been demonstrated that high levels of vesicular zinc are localized in the presynaptic terminals of the granule cells of the dentate gyrus (dg) and that neurogenesis occurs in the subgranular zone (sgz). |
2017-11-06 |
2023-08-13 |
rat |
| D Zhang, X Wang, B Wang, J C Garza, X Fang, J Wang, P E Scherer, R Brenner, W Zhang, X-Y L. Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors. Molecular psychiatry. vol 22. issue 7. 2017-11-02. PMID:27137743. |
infusions of adiponectin into the dentate gyrus (dg) of the hippocampus in fear-conditioned mice facilitated extinction of contextual fear. |
2017-11-02 |
2023-08-13 |
mouse |
| Brian W Jones, Jennifer Deem, Thomas J Younts, Michael Weisenhaus, Christina A Sanford, Margaret C Slack, Jenesa Chin, Daniela Nachmanson, Alex McKennon, Pablo E Castillo, G Stanley McKnigh. Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination. eLife. vol 5. 2017-10-31. PMID:27911261. |
the hippocampal dentate gyrus (dg) is thought to be responsible for processing and encoding distinct contextual associations in response to highly similar inputs. |
2017-10-31 |
2023-08-13 |
mouse |
| Guerrero Aguilera María de Los Angeles, Rubio Osornio María Del Carmen, Portillo Martínez Wendy, Retana-Márquez Socorr. Tactile stimulation effects on hippocampal neurogenesis and spatial learning and memory in prenatally stressed rats. Brain research bulletin. vol 124. 2017-10-26. PMID:26993794. |
neurogenesis in the dentate gyrus (dg) of the hippocampus is increased by spatial learning and postnatal stimulation. |
2017-10-26 |
2023-08-13 |
rat |
| Guangxie Li, Jing Lv, Jun Wang, Peng Wan, Yingshun Li, Haiying Jiang, Qinghua Ji. GABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia. Brain research bulletin. vol 124. 2017-10-26. PMID:27181927. |
the roles of γ-aminobutyric acid (gaba) and gabab receptors of the hippocampal dentate gyrus (dg) in spatial learning and memory impairment were investigated in a rat model of vascular dementia (vad) established by permanent bilateral carotid occlusion. |
2017-10-26 |
2023-08-13 |
rat |
| Sabine Sellner, Ricardo Paricio-Montesinos, Alena Spieß, Annette Masuch, Daniel Erny, Laura A Harsan, Dominik V Elverfeldt, Marius Schwabenland, Knut Biber, Ori Staszewski, Sergio Lira, Steffen Jung, Marco Prinz, Thomas Blan. Microglial CX3CR1 promotes adult neurogenesis by inhibiting Sirt 1/p65 signaling independent of CX3CL1. Acta neuropathologica communications. vol 4. issue 1. 2017-10-25. PMID:27639555. |
here we report that microglia in the dentate gyrus (dg) of cx3cr1 (-/-) mice displayed elevated microglial sirtuin 1 (sirt1) expression levels and nuclear factor kappa-light-chain-enhancer of activated b cells (nf-kb) p65 activation, despite unaltered morphology when compared to cx3cr1 (+/-) or cx3cr1 (+/+) controls. |
2017-10-25 |
2023-08-13 |
mouse |
| Jong Won Lee, Min Whan Jun. Separation or binding? Role of the dentate gyrus in hippocampal mnemonic processing. Neuroscience and biobehavioral reviews. vol 75. 2017-10-24. PMID:28174077. |
as a major component of the hippocampal trisynaptic circuit, the dentate gyrus (dg) relays inputs from the entorhinal cortex to the ca3 subregion. |
2017-10-24 |
2023-08-13 |
Not clear |
| Aparajita Bhattacharya, Harsh Desai, Thomas B DeMarse, Bruce C Wheeler, Gregory J Brewe. Repeating Spatial-Temporal Motifs of CA3 Activity Dependent on Engineered Inputs from Dentate Gyrus Neurons in Live Hippocampal Networks. Frontiers in neural circuits. vol 10. 2017-10-23. PMID:27445701. |
anatomical and behavioral studies, and in vivo and slice electrophysiology of the hippocampus suggest specific functions of the dentate gyrus (dg) and the ca3 subregions, but the underlying activity dynamics and repeatability of information processing remains poorly understood. |
2017-10-23 |
2023-08-13 |
Not clear |
| Daniele Poli, Srikanth Thiagarajan, Thomas B DeMarse, Bruce C Wheeler, Gregory J Brewe. Sparse and Specific Coding during Information Transmission between Co-cultured Dentate Gyrus and CA3 Hippocampal Networks. Frontiers in neural circuits. vol 11. 2017-10-23. PMID:28321182. |
to better understand encoding and decoding of stimulus information in two specific hippocampal sub-regions, we isolated and co-cultured rat primary dentate gyrus (dg) and ca3 neurons within a two-chamber device with axonal connectivity via micro-tunnels. |
2017-10-23 |
2023-08-13 |
rat |
| Shahid Ali Shah, Mehtab Khan, Myeung-Hoon Jo, Min Gi Jo, Faiz Ul Amin, Myeong Ok Ki. Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)-Induced Oxidative Stress to Rescue Postnatal Rat Brain. CNS neuroscience & therapeutics. vol 23. issue 1. 2017-10-17. PMID:27421686. |
here, we provided the first detailed description of the mechanism of melatonin neuroprotection against lps-induced oxidative stress, acute neuroinflammation, and neurodegeneration in the hippocampal dentate gyrus (dg) region of the postnatal day 7 (pnd7) rat brain. |
2017-10-17 |
2023-08-13 |
rat |
| Xiaoxue Du, Xue Huo, Yang Yang, Zhiying Hu, Benson O A Botchway, Yuting Jiang, Marong Fan. miR-124 downregulates BACE 1 and alters autophagy in APP/PS1 transgenic mice. Toxicology letters. vol 280. 2017-10-17. PMID:28867212. |
in this study, 7-month-old app/ps1 transgenic mice were transfected with mir-124 lentiviral vectors, injected bilaterally into the dentate gyrus (dg) of mice hippocampi. |
2017-10-17 |
2023-08-13 |
mouse |
| Wei Lu, Shu Yang, Lei Zhang, Lin Chen, Feng-Lei Chao, Yan-Min Luo, Qian Xiao, Heng-Wei Gu, Rong Jiang, Yong Tan. Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer's Disease. Current Alzheimer research. vol 13. issue 9. 2017-10-16. PMID:26971933. |
our results showed that spatial learning and memory performance was significantly impaired in the tg2576 mice compared to the wild type (wt) controls and that the myelinated fiber length in the hippocampal dentate gyrus (dg) was markedly decreased from 0.33 ± 0.03 km in the wt controls to 0.17 ± 0.02 km in the tg2576 mice at 10 months of age. |
2017-10-16 |
2023-08-13 |
mouse |