| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fiorenza Stagni, Alessandra Raspanti, Andrea Giacomini, Sandra Guidi, Marco Emili, Elisabetta Ciani, Alessandro Giuliani, Andrea Bighinati, Laura Calzà, Jacopo Magistretti, Renata Bartesagh. Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome. Neurobiology of disease. vol 103. 2018-03-02. PMID:28359846. |
we found that in treated ts65dn mice the pool of proliferating cells in the hippocampal dentate gyrus (dg) and total number of granule neurons were still restored as was the number of pre- and postsynaptic terminals in the stratum lucidum of ca3, the site of termination of the mossy fibers from the dg. |
2018-03-02 |
2023-08-13 |
mouse |
| Emily R White, Cristina Pinar, Crystal A Bostrom, Alicia Meconi, Brian R Christi. Mild Traumatic Brain Injury Produces Long-Lasting Deficits in Synaptic Plasticity in the Female Juvenile Hippocampus. Journal of neurotrauma. vol 34. issue 5. 2018-03-01. PMID:27735217. |
in female rats, the dentate gyrus (dg) region ipsilateral to the impact showed a significant reduction in long-term potentiation (ltp) at 1 day, which persisted to 28 days following injury. |
2018-03-01 |
2023-08-13 |
rat |
| Hui Shen, Jie Wang, Dan Jiang, Pei Xu, Xiaolu Zhu, Yuanyuan Zhang, Xing Yu, Moo-Ho Won, Pei Qing Su, Bing Chun Ya. Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the D-Galactose-Induced Aging Mice via Its Antioxidant Effects. Cellular and molecular neurobiology. vol 37. issue 5. 2018-02-23. PMID:27734244. |
in this study, we aimed to observe the effects of tpm on cell proliferation and neuronal differentiation in the dentate gyrus (dg) of the d-galactose-induced aging mice by ki-67 and doublecortin (dcx) immunohistochemistry. |
2018-02-23 |
2023-08-13 |
mouse |
| O Hadad-Ophir, Z Ardi, N Brande-Eilat, O Kehat, R Anunu, G Richter-Levi. Exposure to prolonged controllable or uncontrollable stress affects GABAergic function in sub-regions of the hippocampus and the amygdala. Neurobiology of learning and memory. vol 138. 2018-02-22. PMID:27321164. |
our findings reveal similar alterations in gad65 in bla for both controllable and uncontrollable stress exposure, but differential alterations in gad65 and npy in the dorsal dentate gyrus (dg). |
2018-02-22 |
2023-08-13 |
Not clear |
| Yuxue Chen, Lu Liu, Mengzhu Li, Ensheng Yao, Jiahuan Hao, Yuanji Dong, Xiaolong Zheng, Xinghua Li. Expression of human Tau40 in the medial entorhinal cortex impairs synaptic plasticity and associated cognitive functions in mice. Biochemical and biophysical research communications. vol 496. issue 3. 2018-02-22. PMID:28472625. |
the memory function and long-term potentiation (ltp) of dentate gyrus (dg) were significantly impaired by overexpression of htau40 in mec after transduction at 3 and 6 months. |
2018-02-22 |
2023-08-13 |
mouse |
| Tie-Yuan Zhang, Christopher L Keown, Xianglan Wen, Junhao Li, Dulcie A Vousden, Christoph Anacker, Urvashi Bhattacharyya, Richard Ryan, Josie Diorio, Nicholas O'Toole, Jason P Lerch, Eran A Mukamel, Michael J Meane. Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus. Nature communications. vol 9. issue 1. 2018-02-22. PMID:29352183. |
the hippocampal dentate gyrus (dg) is a major site for experience-dependent plasticity associated with sustained transcriptional alterations, potentially mediated by epigenetic modifications. |
2018-02-22 |
2023-08-13 |
mouse |
| Ling-Yu Yang, Nigel H Greig, Ya-Ni Huang, Tsung-Hsun Hsieh, David Tweedie, Qian-Sheng Yu, Barry J Hoffer, Yu Luo, Yu-Chieh Kao, Jia-Yi Wan. Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury. Neurobiology of disease. vol 96. 2018-02-09. PMID:27553877. |
fluoro-jade c was used to stain hippocampal sub-regions, including ca1 and dentate gyrus (dg), for cellular degeneration. |
2018-02-09 |
2023-08-13 |
rat |
| Tatiana Melnikova, DaMin Park, Lauren Becker, Deidre Lee, Eugenia Cho, Nuzhat Sayyida, Jing Tian, Karen Bandeen-Roche, David R Borchelt, Alena V Savonenk. Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer's disease. Neurobiology of disease. vol 96. 2018-02-09. PMID:27569580. |
both males and females showed atrophy of the dentate gyrus (dg) of the dorsal hippocampus, associated with widening of the pyramidal layer of the ca1 area in both sexes. |
2018-02-09 |
2023-08-13 |
mouse |
| S Y Yau, C A Bostrom, J Chiu, C J Fontaine, S Sawchuk, A Meconi, R C Wortman, E Truesdell, A Truesdell, C Chiu, B N Hryciw, B D Eadie, M Ghilan, B R Christi. Impaired bidirectional NMDA receptor dependent synaptic plasticity in the dentate gyrus of adult female Fmr1 heterozygous knockout mice. Neurobiology of disease. vol 96. 2018-02-09. PMID:27659109. |
we, and others, have recently reported that there is significant impairment in n-methyl-d-aspartate receptor (nmdar)-dependent long-term potentiation (ltp) and long-term depression (ltd) in the hippocampal dentate gyrus (dg) of male fmr1 knock out mice. |
2018-02-09 |
2023-08-13 |
mouse |
| Majid Motaghinejad, Manijeh Motevalian, Fatemeh Babalouei, Mohammad Abdollahi, Mansour Heidari, Zahra Madj. Possible involvement of CREB/BDNF signaling pathway in neuroprotective effects of topiramate against methylphenidate induced apoptosis, oxidative stress and inflammation in isolated hippocampus of rats: Molecular, biochemical and histological evidences. Brain research bulletin. vol 132. 2018-02-09. PMID:28552672. |
expression of total (inactive) and phosphorylated (active) creb and bdnf were also measured in gene and protein levels in dentate gyrus (dg) and ca1 areas of hippocampus. |
2018-02-09 |
2023-08-13 |
rat |
| Yanbo Ma, Takashi Matsuwaki, Keitaro Yamanouchi, Masugi Nishihar. Glucocorticoids Suppress the Protective Effect of Cyclooxygenase-2-Related Signaling on Hippocampal Neurogenesis Under Acute Immune Stress. Molecular neurobiology. vol 54. issue 3. 2018-02-07. PMID:26910812. |
treatment of rats with lps significantly decreased neurogenesis in the dentate gyrus (dg) of the hippocampus, and this inhibitory effect of lps on neurogenesis was reversed by the glucocorticoid receptor antagonist ru486. |
2018-02-07 |
2023-08-13 |
rat |
| Thomas R Groves, Jing Wang, Marjan Boerma, Antiño R Alle. Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method. Journal of visualized experiments : JoVE. issue 124. 2018-02-07. PMID:28671647. |
the data presented show that the golgi staining method effectively stained the mature neurons in the ca1, the ca3, and the dentate gyrus (dg) of the hippocampus. |
2018-02-07 |
2023-08-13 |
mouse |
| D J Hamilton, C M White, C L Rees, D W Wheeler, G A Ascol. Molecular fingerprinting of principal neurons in the rodent hippocampus: A neuroinformatics approach. Journal of pharmaceutical and biomedical analysis. vol 144. 2018-02-05. PMID:28549853. |
here we focus on the principal cell layers of dentate gyrus (dg), ca3, ca2, and ca1, which together contain approximately 90% of hippocampal neurons. |
2018-02-05 |
2023-08-13 |
mouse |
| Joaquín Pardo, Maia Uriarte, Gloria M Cónsole, Paula C Reggiani, Tiago F Outeiro, Gustavo R Morel, Rodolfo G Goy. Insulin-like growth factor-I gene therapy increases hippocampal neurogenesis, astrocyte branching and improves spatial memory in female aging rats. The European journal of neuroscience. vol 44. issue 4. 2018-02-01. PMID:27188415. |
in the dentate gyrus (dg) of the hippocampus, the igf-i group showed a higher number of immature neurons than the dsred controls. |
2018-02-01 |
2023-08-13 |
rat |
| Spyridon Chavlis, Panayiota Poiraz. Pattern separation in the hippocampus through the eyes of computational modeling. Synapse (New York, N.Y.). vol 71. issue 6. 2018-02-01. PMID:28316111. |
the dentate gyrus (dg) in particular has long been hypothesized to implement pattern separation by detecting and storing similar inputs as distinct representations. |
2018-02-01 |
2023-08-13 |
Not clear |
| Cong Luo, Ryuta Koyama, Yuji Ikegay. Microglia engulf viable newborn cells in the epileptic dentate gyrus. Glia. vol 64. issue 9. 2018-01-31. PMID:27301702. |
microglia, which are the brain's resident immune cells, engulf dead neural progenitor cells during adult neurogenesis in the subgranular zone (sgz) of the dentate gyrus (dg). |
2018-01-31 |
2023-08-13 |
mouse |
| Min-Shan Lin, Wen-Chao Xiong, Shu-Ji Li, Zhi Gong, Xiong Cao, Xiao-Jing Kuang, Yuan Zhang, Tian-Ming Gao, Naguib Mechawar, Ce Liu, Xin-Hong Zh. α2-glycine receptors modulate adult hippocampal neurogenesis and spatial memory. Developmental neurobiology. vol 77. issue 12. 2018-01-31. PMID:29057625. |
adult hippocampal neurogenesis (ahn) is the process by which new granule cell neurons are added to the dentate gyrus (dg) throughout adulthood. |
2018-01-31 |
2023-08-13 |
mouse |
| Valentina Mastrorilli, Chiara Scopa, Daniele Saraulli, Marco Costanzi, Raffaella Scardigli, Jean-Pierre Rouault, Stefano Farioli-Vecchioli, Felice Tiron. Physical exercise rescues defective neural stem cells and neurogenesis in the adult subventricular zone of Btg1 knockout mice. Brain structure & function. vol 222. issue 6. 2018-01-30. PMID:28247022. |
adult neurogenesis occurs throughout life in the dentate gyrus (dg) and the subventricular zone (svz), where glia-like stem cells generate new neurons. |
2018-01-30 |
2023-08-13 |
mouse |
| Kevin N Hascup, Erin R Hascu. Soluble Amyloid-β42 Stimulates Glutamate Release through Activation of the α7 Nicotinic Acetylcholine Receptor. Journal of Alzheimer's disease : JAD. vol 53. issue 1. 2018-01-29. PMID:27163813. |
because aβ42 binds the α7 nicotinic acetylcholine receptors (α7nachrs) located presynaptically on glutamatergic terminals, involved with hippocampal dependent learning and memory, we examined the effects of the human, monomeric isoform of aβ42 on glutamate release in the dentate gyrus (dg), ca3, and ca1, of isoflurane anesthetized, 6-9 month old male c57bl/6j mice. |
2018-01-29 |
2023-08-13 |
mouse |
| Yanjun Sun, Steven F Grieco, Todd C Holmes, Xiangmin X. Local and Long-Range Circuit Connections to Hilar Mossy Cells in the Dentate Gyrus. eNeuro. vol 4. issue 2. 2018-01-29. PMID:28451637. |
hilar mossy cells are the prominent glutamatergic cell type in the dentate hilus of the dentate gyrus (dg); they have been proposed to have critical roles in the dg network. |
2018-01-29 |
2023-08-13 |
mouse |