| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Kim, P Mahlber. Immunochemical localization of tetrahydrocannabinol (THC) in cryofixed glandular trichomes of Cannabis (Cannabaceae). American journal of botany. vol 84. issue 3. 2012-10-02. PMID:21708587. |
delta 9-tetrahydrocannabinol (thc) localization in glandular trichomes and bracteal tissues of cannabis, prepared by high pressure cryofixation-cryosubstitution, was examined with a monoclonal antibody-colloidal gold probe by electron microscopy (em). |
2012-10-02 |
2023-08-12 |
Not clear |
| Rebecca Andrews, Sue Paterso. Production of identical retention times and mass spectra for {delta}9-tetrahydrocannabinol and cannabidiol following derivatization with trifluoracetic anhydride with 1,1,1,3,3,3-hexafluoroisopropanol*. Journal of analytical toxicology. vol 36. issue 1. 2012-06-11. PMID:22290754. |
production of identical retention times and mass spectra for {delta}9-tetrahydrocannabinol and cannabidiol following derivatization with trifluoracetic anhydride with 1,1,1,3,3,3-hexafluoroisopropanol*. |
2012-06-11 |
2023-08-12 |
Not clear |
| Aurélia Garry, Virginie Rigourd, Ammar Amirouche, Valérie Fauroux, Sylvie Aubry, Raphaël Serrea. Cannabis and breastfeeding. Journal of toxicology. vol 2009. 2011-07-14. PMID:20130780. |
the active substance of cannabis is the delta 9 tetrahydrocannabinol (thc). |
2011-07-14 |
2023-08-12 |
human |
| Anna Minkkilä, Susanna Saario, Tapio Nevalaine. Discovery and development of endocannabinoid-hydrolyzing enzyme inhibitors. Current topics in medicinal chemistry. vol 10. issue 8. 2011-05-02. PMID:20370710. |
they recognize and activate the cannabinoid cb(1) and cb(2) receptors, the molecular targets for delta(9)-tetrahydrocannabinol (delta(9)-thc) in marijuana evoking several beneficial therapeutic effects. |
2011-05-02 |
2023-08-12 |
Not clear |
| K B E Böcker, J Gerritsen, C C Hunault, M Kruidenier, Tj T Mensinga, J L Keneman. Cannabis with high δ9-THC contents affects perception and visual selective attention acutely: an event-related potential study. Pharmacology, biochemistry, and behavior. vol 96. issue 1. 2011-02-23. PMID:20417659. |
this study addressed the effects of exposure to cannabis with up to 69.4mg delta(9)-tetrahydrocannabinol (thc) on event-related potentials (erps) recorded during a visual selective attention task. |
2011-02-23 |
2023-08-12 |
Not clear |
| Elissandro Soares Emídio, Vanessa de Menezes Prata, Haroldo Silveira Dóre. Validation of an analytical method for analysis of cannabinoids in hair by headspace solid-phase microextraction and gas chromatography-ion trap tandem mass spectrometry. Analytica chimica acta. vol 670. issue 1-2. 2011-01-13. PMID:20685418. |
the development of an analytical method for the determination of delta(9)-tetrahydrocannabinol (thc), cannabidiol (cbd) and cannabinol (cbn) in samples of human hair is described. |
2011-01-13 |
2023-08-12 |
human |
| C Pope, R Mechoulam, L Parson. Endocannabinoid signaling in neurotoxicity and neuroprotection. Neurotoxicology. vol 31. issue 5. 2010-12-21. PMID:19969019. |
the mechanism for how delta(9)-tetrahydrocannabinol (thc), the active constituent of cannabis, elicits these neurological effects remained elusive until relatively recently, when specific g-protein coupled receptors were discovered that appeared to mediate cellular actions of thc. |
2010-12-21 |
2023-08-12 |
Not clear |
| C E Pinto, E Moura, M P Serrão, M J Martins, M A Vieira-Coelh. Effect of (-)-Delta(9)-tetrahydrocannabinoid on the hepatic redox state of mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 43. issue 4. 2010-12-06. PMID:20445947. |
(-)-delta(9)-tetrahydrocannabinol (delta(9)-thc), a psychoactive component of marijuana, has been reported to induce oxidative damage in vivo and in vitro. |
2010-12-06 |
2023-08-12 |
mouse |
| Sarah Geiger, Kathrin Nickl, Erich H Schneider, Roland Seifert, Jörg Heilman. Establishment of recombinant cannabinoid receptor assays and characterization of several natural and synthetic ligands. Naunyn-Schmiedeberg's archives of pharmacology. vol 382. issue 2. 2010-11-29. PMID:20617431. |
the suitability of the assay for screening procedures was also proven by detecting the activity of delta(9)-thc in a matrix of other less active compounds (delta(9)-thc-free cannabis sativa extract). |
2010-11-29 |
2023-08-12 |
human |
| Elissandro Soares Emídio, Vanessa de Menezes Prata, Fernando José Malagueño de Santana, Haroldo Silveira Dóre. Hollow fiber-based liquid phase microextraction with factorial design optimization and gas chromatography-tandem mass spectrometry for determination of cannabinoids in human hair. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 878. issue 24. 2010-11-15. PMID:20655815. |
a new method, based on hollow fiber liquid-phase microextraction (hf-lpme) and gas chromatography-tandem mass spectrometry (gc-msms), was developed for determination of delta(9)-tetrahydrocannabinol (thc), cannabidiol (cbd) and cannabinol (cbn) in samples of human hair. |
2010-11-15 |
2023-08-12 |
human |
| Celia J A Morgan, Tom P Freeman, Gráinne L Schafer, H Valerie Curra. Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 9. 2010-10-28. PMID:20428110. |
cannabidiol attenuates the appetitive effects of delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis. |
2010-10-28 |
2023-08-12 |
Not clear |
| Celia J A Morgan, Tom P Freeman, Gráinne L Schafer, H Valerie Curra. Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 9. 2010-10-28. PMID:20428110. |
worldwide cannabis dependence is increasing, as is the concentration of delta(9)-tetrahydrocannabinol (thc) in street cannabis. |
2010-10-28 |
2023-08-12 |
Not clear |
| Nora Laaris, Cameron H Good, Carl R Lupic. Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus. Neuropharmacology. vol 59. issue 1-2. 2010-10-20. PMID:20417220. |
marijuana impairs learning and memory through actions of its psychoactive constituent, delta-9-tetrahydrocannabinol (delta(9)-thc), in the hippocampus, through activation of cannabinoid cb1 receptors (cb1r). |
2010-10-20 |
2023-08-12 |
mouse |
| Leonora E Long, Rose Chesworth, Jonathon C Arnold, Tim Kar. A follow-up study: acute behavioural effects of Delta(9)-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice. Psychopharmacology. vol 211. issue 3. 2010-10-15. PMID:20571781. |
we showed previously that male heterozygous neuregulin 1 transmembrane domain (nrg1 het) mice are more sensitive to some effects of the psychotropic cannabis constituent delta(9)-tetrahydrocannabinol (thc). |
2010-10-15 |
2023-08-12 |
mouse |
| Emma L Scotter, Mary E Abood, Michelle Glas. The endocannabinoid system as a target for the treatment of neurodegenerative disease. British journal of pharmacology. vol 160. issue 3. 2010-10-14. PMID:20590559. |
the discovery of the psychoactive component of cannabis resin, delta(9)-tetrahydrocannabinol (delta(9)-thc) occurred long before the serendipitous identification of a g-protein coupled receptor at which delta(9)-thc is active in the brain. |
2010-10-14 |
2023-08-12 |
human |
| Daniel T Malone, Matthew N Hill, Tiziana Rubin. Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models. British journal of pharmacology. vol 160. issue 3. 2010-10-14. PMID:20590561. |
therefore changes in endocannabinoid activity during this specific developmental phase, induced by the psychoactive component of marijuana, delta(9)-tetrahydrocannabinol, might lead to subtle but lasting neurobiological changes that can affect brain functions and behaviour. |
2010-10-14 |
2023-08-12 |
human |
| Jürg Gertsch, Roger G Pertwee, Vincenzo Di Marz. Phytocannabinoids beyond the Cannabis plant - do they exist? British journal of pharmacology. vol 160. issue 3. 2010-10-14. PMID:20590562. |
the major psychoactive cannabis constituent delta(9)-tetrahydrocannabinol (delta(9)-thc) potently activates the g-protein-coupled cannabinoid receptor cb(1) and also modulates the cannabinoid receptor cb(2). |
2010-10-14 |
2023-08-12 |
human |
| Katherine W Falenski, Andrew J Thorpe, Joel E Schlosburg, Benjamin F Cravatt, Rehab A Abdullah, Tricia H Smith, Dana E Selley, Aron H Lichtman, Laura J Sim-Selle. FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 8. 2010-09-17. PMID:20357755. |
repeated administration of delta(9)-tetrahydrocannabinol (thc), the primary psychoactive constituent of cannabis sativa, induces profound tolerance that correlates with desensitization and downregulation of cb(1) cannabinoid receptors in the cns. |
2010-09-17 |
2023-08-12 |
mouse |
| P Lazzari, P Fadda, G Marchese, G L Casu, L Pan. Antinociceptive activity of Delta9-tetrahydrocannabinol non-ionic microemulsions. International journal of pharmaceutics. vol 393. issue 1-2. 2010-09-03. PMID:20399844. |
delta(9)-tetrahydrocannabinol (delta(9)-thc), the major psychoactive constituent of cannabis sativa l., has been widely studied for its potential pharmaceutical application in the treatment of various diseases and disturbs. |
2010-09-03 |
2023-08-12 |
human |
| Vedrana Reichenbach, Josefa Ros, Wladimiro Jiméne. [Endogenous cannabinoids in liver disease: Many darts for a single target]. Gastroenterologia y hepatologia. vol 33. issue 4. 2010-08-31. PMID:19758727. |
endogenous cannabinoids are ubiquitous lipid-signaling molecules able to partially mimic the actions produced by delta(9)-tetrahydrocannabinol, the compound responsible for most of the psychological effects of marijuana. |
2010-08-31 |
2023-08-12 |
Not clear |