| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Les Iversen, Simon Gibbons, Ric Treble, Vincent Setola, Xi-Ping Huang, Bryan L Rot. Neurochemical profiles of some novel psychoactive substances. European journal of pharmacology. vol 700. issue 1-3. 2013-08-05. PMID:23261499. |
thirteen of the test substances acted as inhibitors of monoamine uptake at submicromolar concentrations, including 9 potent inhibitors of the dopamine transporter (dat), 12 potent inhibitors of the norepinephrine transporter (net) and 4 potent inhibitors of the serotonin transporter (sert). |
2013-08-05 |
2023-08-12 |
human |
| John P M Finber. Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson's Disease with Neuroprotective Potential. Rambam Maimonides medical journal. vol 1. issue 1. 2013-08-05. PMID:23908775. |
following subchronic administration to normal rats, rasagiline increases levels of dopamine in striatal microdialysate, possibly by the build-up of β-phenylethylamine, which is an excellent substrate for mao-b, and is an effective inhibitor of the plasma membrane dopamine transporter (dat). |
2013-08-05 |
2023-08-12 |
human |
| Shu Yang, Dan-Dan Xue, Bo Wu, Hai-Mei Sun, Xiao-Shuang Li, Fang Dong, Wen-Shuai Li, Feng-Qing Ji, De-Shan Zho. Pleiotrophin is involved in the amniotic epithelial cell-induced differentiation of human umbilical cord blood-derived mesenchymal stem cells into dopaminergic neuron-like cells. Neuroscience letters. vol 539. 2013-07-31. PMID:23403104. |
compared to the controls, a higher proportion of treated cells differentiated into da neuron-like cells, indicated by the increased expression of th and dat and the increased dopamine content. |
2013-07-31 |
2023-08-12 |
human |
| Valentina Garibotto, Marie Louise Montandon, Claire Tabouret Viaud, Mohamed Allaoua, Frédéric Assal, Pierre R Burkhard, Osman Ratib, Habib Zaid. Regions of interest-based discriminant analysis of DaTSCAN SPECT and FDG-PET for the classification of dementia. Clinical nuclear medicine. vol 38. issue 3. 2013-07-30. PMID:23357822. |
dopamine transporter (dat) imaging, such as datscan spect, tests the integrity of the nigrostriatal pathway, whereas fdg-pet identifies typical patterns of cortical and subcortical hypometabolism. |
2013-07-30 |
2023-08-12 |
Not clear |
| Tabea H Schauer, Maximilian Lochner, Gabor G Kovac. Nigral Tau pathology and striatal amyloid-β deposition does not correlate with striatal dopamine deficit in Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 12. 2013-07-22. PMID:22664779. |
in the present study, using morphometric immunohistochemistry in 34 cases with ad-related pathology, we evaluated whether nigral burden of tau pathology or striatal burden of amyloid-β deposition correlates with dopamine transporter (dat) expression in the striatum. |
2013-07-22 |
2023-08-12 |
Not clear |
| D Sullivan, J K Pinsonneault, A C Papp, H Zhu, S Lemeshow, D C Mash, W Sade. Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction. Translational psychiatry. vol 3. 2013-07-19. PMID:23340505. |
dopamine transporter dat and receptor drd2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction. |
2013-07-19 |
2023-08-12 |
human |
| D Sullivan, J K Pinsonneault, A C Papp, H Zhu, S Lemeshow, D C Mash, W Sade. Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction. Translational psychiatry. vol 3. 2013-07-19. PMID:23340505. |
here, we focus on the role of aberrant dopaminergic signaling, involving the dopamine transporter dat, a cocaine target, and the dopamine d2 receptor, which physically interacts with dat. |
2013-07-19 |
2023-08-12 |
human |
| Moogeh Baharnoori, Sanjeev K Bhardwaj, Lalit K Srivastav. Effect of maternal lipopolysaccharide administration on the development of dopaminergic receptors and transporter in the rat offspring. PloS one. vol 8. issue 1. 2013-07-19. PMID:23349891. |
using ligand autoradiography, d1 and d2 dopamine receptors (d1r, d2r) and dopamine transporter (dat) binding levels were measured in the prefrontal cortex (pfc) and sub cortical regions (dorsal striatum and nucleus accumbens core and shell) at pre pubertal (p35) and post pubertal ages (p60). |
2013-07-19 |
2023-08-12 |
rat |
| Rong Chen, Conor P Daining, Haiguo Sun, Rheaclare Fraser, Stephanie L Stokes, Michael Leitges, Margaret E Gneg. Protein kinase Cβ is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter. Journal of neurochemistry. vol 125. issue 5. 2013-07-19. PMID:23458603. |
the strength and duration of extracellular dopamine concentrations are regulated by the presynaptic dopamine transporter (dat) and dopamine d2 autoreceptors (d2autors). |
2013-07-19 |
2023-08-12 |
mouse |
| Mei-Chun Hsiao, Kun-Ju Lin, Chia-Yih Liu, David Beck Schat. The interaction between dopamine transporter function, gender differences, and possible laterality in depression. Psychiatry research. vol 211. issue 1. 2013-07-12. PMID:23036826. |
the dopamine transporter (dat) can reflect the general state of striatal dopamine activity. |
2013-07-12 |
2023-08-12 |
human |
| Noelia Granado, Isabel Lastres-Becker, Sara Ares-Santos, Idaira Oliva, Eduardo Martin, Antonio Cuadrado, Rosario Moratall. Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum. Glia. vol 59. issue 12. 2013-07-08. PMID:21882243. |
we found that nrf2 deficiency exacerbated meth-induced damage to dopamine neurons, shown by an increase in loss of tyrosine hydroxylase (th)- and dopamine transporter (dat)-containing fibers in striatum. |
2013-07-08 |
2023-08-12 |
Not clear |
| Luca Passamonti, Maria Salsone, Nicola Toschi, Antonio Cerasa, Marco Giannelli, Carmelina Chiriaco, Giuseppe Lucio Cascini, Francesco Fera, Aldo Quattron. Dopamine-transporter levels drive striatal responses to apomorphine in Parkinson's disease. Brain and behavior. vol 3. issue 3. 2013-07-04. PMID:23785657. |
we used functional magnetic resonance imaging (fmri) to address how apomorphine, a potent dopamine agonist, influences brain activity associated with working memory in pd patients with variable levels of nigrostriatal degeneration, as assessed via dopamine-transporter (dat) scan. |
2013-07-04 |
2023-08-12 |
Not clear |
| David Devos, Caroline Moreau, Arnaud Delval, Kathy Dujardin, Luc Defebvre, Regis Borde. Methylphenidate : a treatment for Parkinson's disease? CNS drugs. vol 27. issue 1. 2013-07-03. PMID:23160937. |
the currently licensed dopaminergic treatments for pd modulate all the key steps in the dopamine transmission except the most powerful determinant of extracellular dopamine concentrations: the presynaptic dopamine transporter (dat). |
2013-07-03 |
2023-08-12 |
Not clear |
| Tanya Chotibut, Deana M Apple, Rebecca Jefferis, Michael F Salvator. Dopamine transporter loss in 6-OHDA Parkinson's model is unmet by parallel reduction in dopamine uptake. PloS one. vol 7. issue 12. 2013-07-02. PMID:23300642. |
the dopamine transporter (dat) regulates synaptic dopamine (da) in striatum and modulation of dat can affect locomotor activity. |
2013-07-02 |
2023-08-12 |
rat |
| Andrea Varrone, John C Dickson, Livia Tossici-Bolt, Terez Sera, Susanne Asenbaum, Jan Booij, Ozlem L Kapucu, Andreas Kluge, Gitte M Knudsen, Pierre Malick Koulibaly, Flavio Nobili, Marco Pagani, Osama Sabri, Thierry Vander Borght, Koen Van Laere, Klaus Tatsc. European multicentre database of healthy controls for [123I]FP-CIT SPECT (ENC-DAT): age-related effects, gender differences and evaluation of different methods of analysis. European journal of nuclear medicine and molecular imaging. vol 40. issue 2. 2013-06-27. PMID:23160999. |
dopamine transporter (dat) imaging with [(123)i]fp-cit (datscan) is an established diagnostic tool in parkinsonism and dementia. |
2013-06-27 |
2023-08-12 |
Not clear |
| Katherine Barreto-Valer, Roger López-Bellido, Fátima Macho Sánchez-Simón, Raquel E Rodrígue. Modulation by cocaine of dopamine receptors through miRNA-133b in zebrafish embryos. PloS one. vol 7. issue 12. 2013-06-27. PMID:23285158. |
we also analysed the interaction of mir-133b with the pitx3 and pitx3 target genes drd2a and drd2b, tyrosine hydroxylase (th) and dopamine transporter (dat) by microinjection of the pitx3-3'utr sequence. |
2013-06-27 |
2023-08-12 |
zebrafish |
| Katherine Barreto-Valer, Roger López-Bellido, Fátima Macho Sánchez-Simón, Raquel E Rodrígue. Modulation by cocaine of dopamine receptors through miRNA-133b in zebrafish embryos. PloS one. vol 7. issue 12. 2013-06-27. PMID:23285158. |
via mir-133b cocaine would modulate the expression of pitx3 and subsequently of dopamine receptors, dat and th. |
2013-06-27 |
2023-08-12 |
zebrafish |
| b' Susanne B\\xc3\\xa4ck, Mari Raki, Raimo K Tuominen, Atso Raasmaja, Kim Bergstr\\xc3\\xb6m, Pekka T M\\xc3\\xa4nnist\\xc3\\xb. High correlation between in vivo [123I]\\xce\\xb2-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats. EJNMMI research. vol 3. issue 1. 2013-06-27. PMID:23758882.' |
the aim of our study was to evaluate the potential of combined single-photon emission computed tomography/computed tomography (spect/ct) for the detection of differences in 6-ohda-induced partial lesions in a dose- and time-dependent manner using the dopamine transporter (dat) ligand 2β-carbomethoxy-3β-(4-[123i]iodophenyl)tropane ([123i]β-cit). |
2013-06-27 |
2023-08-12 |
rat |
| Daniel Alves Cavagnolli, Andrea Maculano Esteves, Mario Luiz Vieira Castiglione, Ilza Rosa Batista, Rodrigo Afonseca Bressan, Sergio Tufik, Marco Túlio De Mell. Dopamine transporter shown by SPECT in patients with periodic leg movement after acute physical exercise. Medicine and science in sports and exercise. vol 45. issue 2. 2013-06-25. PMID:22935737. |
this study aimed to evaluate dopamine transporter (dat) density in patients with periodic leg movement (plm) shown by [(99mt)tc]trodat-1 single-photon emission computed tomography (spect) imaging and to determine the influence of acute physical exercise (maximal exercise test [met]) on dat densities. |
2013-06-25 |
2023-08-12 |
Not clear |
| Jordy van Enkhuizen, Mark A Geyer, Jared W Youn. Differential effects of dopamine transporter inhibitors in the rodent Iowa gambling task: relevance to mania. Psychopharmacology. vol 225. issue 3. 2013-06-21. PMID:22945515. |
inhibition of the dopamine transporter (dat) can model profiles of altered motor activity and exploration seen in patients with bd. |
2013-06-21 |
2023-08-12 |
Not clear |