| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shu-Ying Liu, Jian-Jun Wu, Jue Zhao, Si-Fei Huang, Yi-Xuan Wang, Jing-Jie Ge, Ping Wu, Chuan-Tao Zuo, Zheng-Tong Ding, Jian Wan. Onset-related subtypes of Parkinson's disease differ in the patterns of striatal dopaminergic dysfunction: A positron emission tomography study. Parkinsonism & related disorders. vol 21. issue 12. 2016-09-12. PMID:26559130. |
this study investigated whether the two subtypes differ in the pattern of dysfunction in striatal (caudate and putamen) dopaminergic system and if the dopamine transporter (dat) imaging patterns are associated with the clinical features of corresponding pd subtype. |
2016-09-12 |
2023-08-13 |
Not clear |
| Irina Baetu, Nicholas R Burns, Kristi Urry, Girolamo Giovanni Barbante, Julia B Pitche. Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans. Neurobiology of learning and memory. vol 125. 2016-09-09. PMID:26419600. |
in particular, we investigated variations in genes that code for the catechol-o-methyltransferase (comt) enzyme, the dopamine transporter (dat) and dopamine d1 and d2 receptors (drd1 and drd2). |
2016-09-09 |
2023-08-13 |
human |
| Irina Baetu, Nicholas R Burns, Kristi Urry, Girolamo Giovanni Barbante, Julia B Pitche. Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans. Neurobiology of learning and memory. vol 125. 2016-09-09. PMID:26419600. |
comt and the dat regulate dopamine availability in the prefrontal cortex and the striatum, respectively, two key regions recruited during learning, whereas dopamine d1 and d2 receptors are thought to be involved in long-term potentiation and depression, respectively. |
2016-09-09 |
2023-08-13 |
human |
| Ioannis U Isaias, Paula Trujillo, Paul Summers, Giorgio Marotta, Luca Mainardi, Gianni Pezzoli, Luigi Zecca, Antonella Cost. Neuromelanin Imaging and Dopaminergic Loss in Parkinson's Disease. Frontiers in aging neuroscience. vol 8. 2016-09-06. PMID:27597825. |
striatal dopaminergic innervation was measured as density of dopamine transporter (dat) by means of single-photon emission computed tomography and [(123)i] n-ω-fluoropropyl-2b-carbomethoxy-3b-(4-iodophenyl) tropane. |
2016-09-06 |
2023-08-13 |
human |
| Emily Hensleigh, Laurel M Pritchar. Maternal separation increases methamphetamine-induced damage in the striatum in male, but not female rats. Behavioural brain research. vol 295. 2016-09-05. PMID:25535855. |
seven days after treatment, rats were euthanized and striatum was collected for quantification of tyrosine hydroxylase (th) and dopamine transporters (dat) content by western blot. |
2016-09-05 |
2023-08-13 |
rat |
| Shinichi Takeshima, Ikuko Takeda, Keitaro Kobatake, Toru Yamashita, Koji Abe, Masaru Kuriyam. [SCA6 presenting parkinsonism without ataxia--A case report]. Rinsho shinkeigaku = Clinical neurology. vol 55. issue 4. 2016-09-01. PMID:25904253. |
striatal dopamine transporter (dat) density was evaluated using i(123)-fp-cit. |
2016-09-01 |
2023-08-13 |
Not clear |
| Goichi Beck, Koei Shinzawa, Hideki Hayakawa, Kousuke Baba, Hisae Sumi-Akamaru, Yoshihide Tsujimoto, Hideki Mochizuk. Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A2β Knockout Mice. PloS one. vol 11. issue 4. 2016-09-01. PMID:27078024. |
at all clinical stages, nerve terminals in the striatum were immunopositive for tyrosine hydroxylase (th) and dopamine transporter (dat) in wild-type (wt) control mice. |
2016-09-01 |
2023-08-13 |
mouse |
| Olga Waln, Ying Wu, Reid Perlman, Juliet Wendt, Anh K Van, Joseph Jankovi. Dopamine transporter imaging in essential tremor with and without parkinsonian features. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 11. 2016-08-30. PMID:26133163. |
although dopamine transporter (dat) imaging is usually normal in et, some studies found mild dopaminergic deficit in et patients compared to healthy controls (hc). |
2016-08-30 |
2023-08-13 |
Not clear |
| Krasnodara N Cameron, Ernesto Solis, Iwona Ruchala, Louis J De Felice, Jose M Elti. Amphetamine activates calcium channels through dopamine transporter-mediated depolarization. Cell calcium. vol 58. issue 5. 2016-08-17. PMID:26162812. |
amph is a dopamine transporter (dat) substrate that inhibits dopamine (da) uptake and is implicated in da release. |
2016-08-17 |
2023-08-13 |
human |
| Weibin Qian, Xinrui Cai, Yingying Wang, Xinying Zhang, Hongmin Zhao, Qiuhai Qian, Zhihong Yang, Zhantao Liu, Junichi Hasegaw. Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of Rats. Yonago acta medica. vol 59. issue 2. 2016-08-05. PMID:27493480. |
we are going to investigate the mechanisms of inhibitive effect of gingerol on cisplatin-induced pica behaviour by studying on both peripheral and central levels, and the effects of gingerol on homeostasis of dopamine (da) transmission: dopamine d2 receptor (d2r), dopamine transporter (dat) and tyrosine hydroxylase (th). |
2016-08-05 |
2023-08-13 |
rat |
| Zhirui Guo, Shasha Xu, Na Du, Jia Liu, Yiyun Huang, Mei Ha. Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system. Neuroscience letters. vol 616. 2016-08-04. PMID:26827716. |
tyrosine hydroxylase (th) and dopamine transporter (dat) levels were detected by immunohistochemistry method. |
2016-08-04 |
2023-08-13 |
mouse |
| Hiroshi Kawaguchi, Hitoshi Shimada, Fumitoshi Kodaka, Masayuki Suzuki, Hitoshi Shinotoh, Shigeki Hirano, Jeff Kershaw, Yuichi Inoue, Masaki Nakamura, Taeko Sasai, Mina Kobayashi, Tetsuya Suhara, Hiroshi It. Principal Component Analysis of Multimodal Neuromelanin MRI and Dopamine Transporter PET Data Provides a Specific Metric for the Nigral Dopaminergic Neuronal Density. PloS one. vol 11. issue 3. 2016-08-03. PMID:26954690. |
as nigral da neurons contain both neuromelanin (nm) and dopamine transporter (dat), decreased intensities in both nm-sensitive mri and dat pet reflect decreased da neuronal density. |
2016-08-03 |
2023-08-13 |
human |
| Zhenyi Liu, Andrew Brown, Dan Fisher, Yumei Wu, Joe Warren, Xiaoxia Cu. Tissue Specific Expression of Cre in Rat Tyrosine Hydroxylase and Dopamine Active Transporter-Positive Neurons. PloS one. vol 11. issue 2. 2016-08-02. PMID:26886559. |
here we report the characterization of two cre rats, tyrosine hydroxylase (th)-cre and dopamine active transporter (dat or slc6a3)-cre, by using a combination of immunohistochemistry (ihc) and mrna fluorescence in situ hybridization (fish) as well as a fluorescent reporter for cre activity. |
2016-08-02 |
2023-08-13 |
mouse |
| R Kolanos, F Sakloth, A D Jain, J S Partilla, M H Baumann, R A Glenno. Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters. ACS chemical neuroscience. vol 6. issue 10. 2016-08-01. PMID:26217965. |
the potent pharmacological effects of α-pvp are presumably mediated by inhibition of dopamine uptake at the dopamine transporter (dat). |
2016-08-01 |
2023-08-13 |
rat |
| Edith Miville-Godbout, Mélanie Bourque, Marc Morissette, Sara Al-Sweidi, Tara Smith, Asuka Mochizuki, Vijitha Senanayake, Dushmanthi Jayasinghe, Li Wang, Dayan Goodenowe, Thérèse Di Paol. Plasmalogen Augmentation Reverses Striatal Dopamine Loss in MPTP Mice. PloS one. vol 11. issue 3. 2016-08-01. PMID:26959819. |
mptp treatment reduced serum plasmalogen levels, striatal contents of dopamine (da) and its metabolites, serotonin, da transporter (dat) and vesicular monoamine transporter 2 (vmat2). |
2016-08-01 |
2023-08-13 |
mouse |
| Udaiyappan Janakiraman, Thamilarasan Manivasagam, Arokiasamy Justin Thenmozhi, Musthafa Mohamed Essa, Rajamani Barathidasan, Chidambaram SaravanaBabu, Gilles J Guillemin, Mohammed A S Kha. Influences of Chronic Mild Stress Exposure on Motor, Non-Motor Impairments and Neurochemical Variables in Specific Brain Areas of MPTP/Probenecid Induced Neurotoxicity in Mice. PloS one. vol 11. issue 1. 2016-07-26. PMID:26765842. |
injections (once in 3.5 days for 5 weeks) of mptp/p or exposure to cms for 4 weeks, the behavioural (motor and non-motor) impairments, levels and expressions of dopamine (da), serotonin (5-ht), daergic markers such as tyrosine hydroxylase (th), dopamine transporter (dat), vesicular monoamine transporters-2 (vmat 2) and α-synuclein in nigrostriatal (striatum (st) and substantia nigra (sn)) and extra-nigrostriatal (hippocampus, cortex and cerebellum) tissues were analysed. |
2016-07-26 |
2023-08-13 |
mouse |
| Darya L Zabelina, Lorenza Colzato, Mark Beeman, Bernhard Homme. Dopamine and the Creative Mind: Individual Differences in Creativity Are Predicted by Interactions between Dopamine Genes DAT and COMT. PloS one. vol 11. issue 1. 2016-07-26. PMID:26783754. |
dopamine and the creative mind: individual differences in creativity are predicted by interactions between dopamine genes dat and comt. |
2016-07-26 |
2023-08-13 |
human |
| Xiao-Yi Ji, Min W. [mRNA expression of dopamine receptor D2 and dopamine transporter in peripheral blood lymphocytes before and after treatment in children with tic disorder]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 18. issue 4. 2016-07-25. PMID:27097571. |
to investigate the mrna expression of dopamine receptor d2 (drd2) and dopamine transporter (dat) in peripheral blood lymphocytes before and after treatment in children with tic disorder (td). |
2016-07-25 |
2023-08-13 |
Not clear |
| Fábio Teixeira Kuhn, Verônica Tironi Dias, Karine Roversi, Luciana Taschetto Vey, Daniele Leão de Freitas, Camila Simonetti Pase, Katiane Roversi, Juliana Cristina Veit, Tatiana Emanuelli, Marilise Escobar Bürge. Cross-Generational trans Fat Consumption Favors Self-Administration of Amphetamine and Changes Molecular Expressions of BDNF, DAT, and D1/D2 Receptors in the Cortex and Hippocampus of Rats. Neurotoxicity research. vol 28. issue 4. 2016-07-21. PMID:26188494. |
anxiety-like symptoms and locomotor index were assessed in elevated plus maze and open-field (of), respectively, while brain molecular expressions of dopaminergic receptors, dopamine transporter (dat), and bdnf were determined in the cortex and hippocampus. |
2016-07-21 |
2023-08-13 |
rat |
| Nora D Volkow, Gene-Jack Wang, Lisa Smith, Joanna S Fowler, Frank Telang, Jean Logan, Dardo Tomas. Recovery of dopamine transporters with methamphetamine detoxification is not linked to changes in dopamine release. NeuroImage. vol 121. 2016-07-20. PMID:26208874. |
methamphetamine's widepread abuse and concerns that it might increase parkinson's disease led us to assess if the reported loss of dopamine transporters (dat) in methamphetamine abusers (ma) reflected damage to dopamine neurons. |
2016-07-20 |
2023-08-13 |
Not clear |