| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luke Gabriel, Zachary Stevens, Haley Melikia. Measuring plasma membrane protein endocytic rates by reversible biotinylation. Journal of visualized experiments : JoVE. issue 34. 2010-01-15. PMID:20032927. |
in the present report, we describe a reversible biotinylation method that we employ to measure the dopamine transporter (dat) endocytic rate. |
2010-01-15 |
2023-08-12 |
Not clear |
| E Zakharova, J Miller, E Unterwald, D Wade, S Izenwasse. Social and physical environment alter cocaine conditioned place preference and dopaminergic markers in adolescent male rats. Neuroscience. vol 163. issue 3. 2010-01-14. PMID:19580849. |
enriched housing (se3) increased dopamine transporter (dat) protein in the nucleus accumbens compared to ii. |
2010-01-14 |
2023-08-12 |
rat |
| Werner J Geldenhuys, Lois-May Bezuidenhout, Dean E Dluze. Effects of a novel dopamine uptake inhibitor upon extracellular dopamine from superfused murine striatal tissue. European journal of pharmacology. vol 619. issue 1-3. 2010-01-14. PMID:19686731. |
the dopamine transporter (dat) plays an important role in substance abuse, schizophrenia, and dopaminergic toxicity associated with the parkinsonian animal model toxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
2010-01-14 |
2023-08-12 |
Not clear |
| Werner J Geldenhuys, Lois-May Bezuidenhout, Dean E Dluze. Effects of a novel dopamine uptake inhibitor upon extracellular dopamine from superfused murine striatal tissue. European journal of pharmacology. vol 619. issue 1-3. 2010-01-14. PMID:19686731. |
it appears that compound 1 exerts these effects primarily through interaction with the dat by blocking dopamine uptake via a calcium-dependent mechanism, and does not lead to extracellular efflux via the dat. |
2010-01-14 |
2023-08-12 |
Not clear |
| Xiaoqin Huang, Howard H Gu, Chang-Guo Zha. Mechanism for cocaine blocking the transport of dopamine: insights from molecular modeling and dynamics simulations. The journal of physical chemistry. B. vol 113. issue 45. 2010-01-14. PMID:19831380. |
molecular modeling and dynamics simulations have been performed to study how cocaine inhibits dopamine transporter (dat) for the transport of dopamine. |
2010-01-14 |
2023-08-12 |
Not clear |
| Francesco Roselli, Nicola M Pisciotta, Robert Perneczky, Michele Pennelli, Maria S Aniello, Maria F De Caro, Ermanno Ferrannini, Bruno Tartaglione, Giovanni Defazio, Giuseppe Rubini, Paolo Livre. Severity of neuropsychiatric symptoms and dopamine transporter levels in dementia with Lewy bodies: a 123I-FP-CIT SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 14. 2010-01-12. PMID:19705471. |
dopamine transporter (dat) imaging with (123)i-labeled ligand n-delta-(fluoropropyl)-2 beta-carbomethoxy-3beta-(4-iodophenyl)tropene ((123)i-fp-cit), which reliably measures midbrain dopaminergic dysfunction, has provided important evidence on the neurobiological substrate of some of these symptoms including apathy and depression. |
2010-01-12 |
2023-08-12 |
Not clear |
| E Escubedo, J Camarasa, C Chipana, S García-Ratés, D Pubil. Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity: pharmacological implications. International review of neurobiology. vol 88. 2010-01-08. PMID:19897077. |
mem also prevents mdma effect on serotonin transporter functionality and meth effect on dopamine transporter (dat), suggesting that behavioral effects of these psychostimulants can also be modulated by mem. |
2010-01-08 |
2023-08-12 |
mouse |
| Masanori Ookubo, Hironori Yokoyama, Hiroyuki Kato, Tsutomu Arak. Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice. Molecular and cellular endocrinology. vol 311. issue 1-2. 2010-01-06. PMID:19631714. |
in the present study, we investigated the time-dependent alterations of dopamine and its metabolites, striatal tyrosine hydroxylase (th) protein, dopamine transporter (dat) protein, glial fibrillary acidic protein (gfap) protein and midbrain th protein and motor function in male and female mice 5h and 1, 3 and 7 days after four administrations of mptp (20mg/kg) at 2-h intervals. |
2010-01-06 |
2023-08-12 |
mouse |
| Hiroko Hagiwara, Masaomi Iyo, Kenji Hashimot. Mithramycin protects against dopaminergic neurotoxicity in the mouse brain after administration of methamphetamine. Brain research. vol 1301. 2010-01-05. PMID:19748494. |
moreover, the combination of pretreatment and subsequent administration of mithramycin (75, 150 or 300 microg/kg) significantly attenuated the reductions of dopamine (da), its major metabolite 3,4-dihydroxyphenylacetic acid (dopac) and da transporter (dat) in the striatum after repeated administration of meth (3 mg/kgx3, 3-h intervals), and these attenuations were dose dependent. |
2010-01-05 |
2023-08-12 |
mouse |
| G Kägi, K P Bhatia, E Tolos. The role of DAT-SPECT in movement disorders. Journal of neurology, neurosurgery, and psychiatry. vol 81. issue 1. 2010-01-05. PMID:20019219. |
dopamine transporter (dat) imaging is a sensitive method to detect presynaptic dopamine neuronal dysfunction, which is a hallmark of neurodegenerative parkinsonism. |
2010-01-05 |
2023-08-12 |
Not clear |
| Aina W Ravna, Ingebrigt Sylte, Svein G Dah. Structure and localisation of drug binding sites on neurotransmitter transporters. Journal of molecular modeling. vol 15. issue 10. 2009-12-31. PMID:19238460. |
the dopamine (dat), serotontin (sert) and noradrenalin (net) transporters are molecular targets for different classes of psychotropic drugs. |
2009-12-31 |
2023-08-12 |
Not clear |
| S Arpin, E Lagrue, S Bodard, S Chalon, P Castelna. Basal ganglia neuroprotection with anticonvulsants after energy stress: a comparative study. Metabolic brain disease. vol 24. issue 3. 2009-12-30. PMID:19789969. |
the membrane dopamine transporter (dat) density, which provides a reliable index of dopaminergic neurons survival in the basal ganglia, was assessed by semi-quantitative autoradiography of the striatum. |
2009-12-30 |
2023-08-12 |
mouse |
| Patrick J Riss, Fabian Debus, René Hummerich, Ulrich Schmidt, Patrick Schloss, Hartmut Lueddens, Frank Roesc. Ex vivo and in vivo evaluation of [18F]PR04.MZ in rodents: a selective dopamine transporter imaging agent. ChemMedChem. vol 4. issue 9. 2009-12-29. PMID:19588472. |
n-4-fluorobut-2-yn-1-yl-2beta-carbomethoxy-3beta-phenyltropane (pr04.mz) has been developed as dopamine transporter (dat) ligand for molecular imaging. |
2009-12-29 |
2023-08-12 |
human |
| Ryosuke Arakawa, Tetsuya Ichimiya, Hiroshi Ito, Akihiro Takano, Masaki Okumura, Hidehiko Takahashi, Harumasa Takano, Fumihiko Yasuno, Motoichiro Kato, Yoshiro Okubo, Tetsuya Suhar. Increase in thalamic binding of [(11)C]PE2I in patients with schizophrenia: a positron emission tomography study of dopamine transporter. Journal of psychiatric research. vol 43. issue 15. 2009-12-24. PMID:19457493. |
previous in vivo imaging studies reported no difference in dopamine transporter (dat) bindings in the striatum between control subjects and patients with schizophrenia. |
2009-12-24 |
2023-08-12 |
human |
| Simone Macrì, Oleg Granstrem, Maria Shumilina, Fernando João Antunes Gomes dos Santos, Alessandra Berry, Luciano Saso, Giovanni Laviol. Resilience and vulnerability are dose-dependently related to neonatal stressors in mice. Hormones and behavior. vol 56. issue 4. 2009-12-22. PMID:19632235. |
offspring attentional set-shifting abilities, central neurotrophic regulation and levels of natural auto-antibodies (na-abs) directed to serotonin (sert) and dopamine (dat) transporters were assessed in adulthood. |
2009-12-22 |
2023-08-12 |
mouse |
| S Padmanabhan, B M Prasa. Sustained depolarization decreases calcium/calmodulin-dependent protein kinase II activity and gene expression in dopamine neurons. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19555740. |
decreased camkii activity was accompanied by a selective decrease in dopamine transporter (dat) mrna, while tyrosine hydroxylase and actin mrna abundance was unaltered. |
2009-12-15 |
2023-08-12 |
rat |
| Jie Lan, Manshu Song, Chunhui Pan, Guoqing Zhuang, Youxin Wang, Wenzhan Ma, Qiaoyun Chu, Qingxuan Lai, Feng Xu, Yanli Li, Lixin Liu, Wei Wan. Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese. Journal of human genetics. vol 54. issue 8. 2009-12-15. PMID:19590515. |
there was evidence that the activities of dopamine transporter (dat) and dopamine d2 receptor (drd2) could be altered in people with speech disfluency. |
2009-12-15 |
2023-08-12 |
Not clear |
| Anna Grzywacz, Jerzy Samochowie. [Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence]. Psychiatria polska. vol 42. issue 3. 2009-12-04. PMID:19899571. |
[case-control, family based and screening for dna sequence variation in the dopamine transporter gene polymorphism dat 1 in alcohol dependence]. |
2009-12-04 |
2023-08-12 |
human |
| Anna Grzywacz, Jerzy Samochowie. [Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence]. Psychiatria polska. vol 42. issue 3. 2009-12-04. PMID:19899571. |
the paper focuses on candidate gene polymorphism and on the role of dopamine transporter gene polymorphism dat 1 in the pathogenesis of alcoholism. |
2009-12-04 |
2023-08-12 |
human |
| Anna Grzywacz, Jerzy Samochowie. [Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence]. Psychiatria polska. vol 42. issue 3. 2009-12-04. PMID:19899571. |
screening for dna sequence variation in the dopamine transporter gene polymorphism dat 1 was determined using abi 310. |
2009-12-04 |
2023-08-12 |
human |