| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dianca R Graham, Anita Sidh. Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior. Journal of neuroscience research. vol 88. issue 8. 2010-07-12. PMID:20077428. |
in this study, we examined the effect of the ha53t mutation during development by analyzing the protein expression of norepinephrine (net), serotonin (sert), and dopamine (dat) transporters in addition to assessing locomotor and anxiety-like behavior. |
2010-07-12 |
2023-08-12 |
mouse |
| Donatella Marazziti, Giorgio Consoli, Irene Masala, Mario Catena Dell'Osso, Stefano Baron. Latest advancements on serotonin and dopamine transporters in lymphocytes. Mini reviews in medicinal chemistry. vol 10. issue 1. 2010-07-12. PMID:20105129. |
different data show that circulating lymphocytes possess functional serotonin and dopamine transporters (sert and dat, respectively). |
2010-07-12 |
2023-08-12 |
Not clear |
| Carolina Ciumas, Tarja-Brita Robins Wahlin, Claudia Espino, Ivanka Savi. The dopamine system in idiopathic generalized epilepsies: identification of syndrome-related changes. NeuroImage. vol 51. issue 2. 2010-07-12. PMID:20188181. |
the dopamine (da) system was investigated with pet and a da transporter (dat) ligand [(11)c]pe2i in 13 patients with jme, 13 with gtcs, and 12 healthy controls. |
2010-07-12 |
2023-08-12 |
Not clear |
| M Garcia-Garcia, F Barceló, I C Clemente, C Escer. The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility. The European journal of neuroscience. vol 31. issue 4. 2010-07-08. PMID:20141527. |
neuropharmacological and human clinical studies have suggested a critical role for striatal dopaminergic function mediated by the dopamine transporter (dat). |
2010-07-08 |
2023-08-12 |
human |
| Alexis Bailey, Athanasios Metaxas, Ream Al-Hasani, Helen L Keyworth, Duncan M Forster, Ian Kitche. Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP-r activation and dopamine transporter binding. The European journal of neuroscience. vol 31. issue 4. 2010-07-08. PMID:20384817. |
a higher density of dopamine transporters (dat) was observed in nucleus accumbens shell and caudate of heroin-treated dba/2j mice compared with heroin-treated c57bl/6j. |
2010-07-08 |
2023-08-12 |
mouse |
| V Roessner, T Sagvolden, T Dasbanerjee, F A Middleton, S V Faraone, S I Walaas, A Becker, A Rothenberger, N Boc. Methylphenidate normalizes elevated dopamine transporter densities in an animal model of the attention-deficit/hyperactivity disorder combined type, but not to the same extent in one of the attention-deficit/hyperactivity disorder inattentive type. Neuroscience. vol 167. issue 4. 2010-07-06. PMID:20211696. |
next, striatal dopamine transporter (dat) density was determined by ligand binding assay in the two adhd-like strains at different developmental stages and after methylphenidate treatment. |
2010-07-06 |
2023-08-12 |
rat |
| Ainhoa Plaza-Zabala, Fernando Berrendero, Juan Suarez, Francisco Javier Bermudez-Silva, Emilio Fernandez-Espejo, Antonia Serrano, Francisco-Javier Pavon, Loren H Parsons, Fernando Rodriguez De Fonseca, Rafael Maldonado, Patricia Robled. Effects of the endogenous PPAR-alpha agonist, oleoylethanolamide on MDMA-induced cognitive deficits in mice. Synapse (New York, N.Y.). vol 64. issue 5. 2010-06-23. PMID:20029832. |
dopamine transporter (dat)-binding sites significantly decreased 4 days after the last mdma administration and pretreatment with both doses of oea prevented this effect. |
2010-06-23 |
2023-08-12 |
mouse |
| Cynthia H Kern, Gregg D Stanwood, Donald R Smit. Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels. Synapse (New York, N.Y.). vol 64. issue 5. 2010-06-23. PMID:20029834. |
brain dopamine d1 and d2-like receptors, and dopamine transporter (dat) densities were determined on pnd 24, and blood and brain mn levels were measured to coincide with behavioral testing (pnd 24, pnd 36). |
2010-06-23 |
2023-08-12 |
rat |
| Cynthia H Kern, Gregg D Stanwood, Donald R Smit. Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels. Synapse (New York, N.Y.). vol 64. issue 5. 2010-06-23. PMID:20029834. |
these behavioral and learning deficits were associated with altered expression of the dopamine d1 and d2 receptors and the dat in prefrontal cortex, nucleus accumbens, and dorsal striatum. |
2010-06-23 |
2023-08-12 |
rat |
| Andre C Felicio, Clecio Godeiro-Junior, Tais S Moriyama, Ming C Shih, Marcelo Q Hoexter, Vanderci Borges, Sonia M A Silva, Patricia de Carvalho Aguiar, Luiz A F Andrade, Rodrigo A Bressan, Henrique B Ferra. Degenerative parkinsonism in patients with psychogenic parkinsonism: A dopamine transporter imaging study. Clinical neurology and neurosurgery. vol 112. issue 4. 2010-06-17. PMID:20061077. |
to evaluate patients with "clinically established" psychogenic parkinsonism (psyp) using single-photon emission computer tomography (spect) with the technetium-99m labeled tracer trodat-1, a dopamine transporter (dat) ligand, and investigate whether these patients have an underlying degenerative parkinsonism. |
2010-06-17 |
2023-08-12 |
Not clear |
| Andre C Felicio, Clecio Godeiro-Junior, Ming C Shih, Vanderci Borges, Sônia M A Silva, Patrícia de Carvalho Aguiar, Marcelo Q Hoexter, Orlando G P Barsottini, Luiz A F Andrade, Rodrigo A Bressan, Henrique B Ferra. Evaluation of patients with Clinically Unclear Parkinsonian Syndromes submitted to brain SPECT imaging using the technetium-99m labeled tracer TRODAT-1. Journal of the neurological sciences. vol 291. issue 1-2. 2010-06-17. PMID:20096859. |
in this study our aim was to evaluate patients with clinically unclear parkinsonian syndromes (cups) submitted to brain spect imaging using the technetium-99m labeled dopamine transporter (dat) tracer trodat-1. |
2010-06-17 |
2023-08-12 |
human |
| G Xu, Z Xiong, Y Yong, Z Wang, Z Ke, Z Xia, Y H. Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum. Neuroscience. vol 167. issue 1. 2010-06-17. PMID:20123001. |
instead, catalpol dose dependently raised the tyrosine hydroxylase (th) neuron number in substantia nigra pars compacta (snpc), the striatal dopamine transporter (dat) density and the striatal glial cell derived neurotrophic factor (gdnf) protein level. |
2010-06-17 |
2023-08-12 |
mouse |
| Jared W Young, Mark A Geye. Action of modafinil--increased motivation via the dopamine transporter inhibition and D1 receptors? Biological psychiatry. vol 67. issue 8. 2010-06-17. PMID:20132929. |
recent evidence suggests that modafinil might block the dopamine transporter (dat) and that the dopamine d1 receptor (d1r) might contribute to modafinil effects. |
2010-06-17 |
2023-08-12 |
Not clear |
| F Pérez-Sánchez, M Milán, P Buendía, M Cano-Jaimez, S Ambrosio, A Rosenthal, I Fariña. Prosurvival effect of human wild-type alpha-synuclein on MPTP-induced toxicity to central but not peripheral catecholaminergic neurons isolated from transgenic mice. Neuroscience. vol 167. issue 2. 2010-06-17. PMID:20156526. |
surprisingly, cultured transgenic ventral mesencephalic fetal dopaminergic neurons exhibit complete resistance to cell death induced by 1-methyl-4-phenylpyridinium ion (mpp(+)) intoxication, without changes in dopamine transporter (dat) surface levels. |
2010-06-17 |
2023-08-12 |
mouse |
| Nicolaas I Bohnen, Martijn L T M Muller, Hiroto Kuwabara, Rakié Cham, Gregory M Constantine, Stephanie A Studensk. Age-associated striatal dopaminergic denervation and falls in community-dwelling subjects. Journal of rehabilitation research and development. vol 46. issue 8. 2010-06-17. PMID:20157861. |
community-dwelling subjects who did not have a clinical diagnosis to explain falls (n = 77: 43 female, 34 male; mean age 61.4 +/- 16.4; range 20-85) completed clinical assessment and brain dopamine transporter (dat) [(11)c]beta-cft (2-beta-carbomethoxy-3beta-(4-fluorophenyl) tropane) positron emission tomography imaging followed by 6 months of prospective fall monitoring using diaries. |
2010-06-17 |
2023-08-12 |
human |
| Steven L Neese, Victor C Wang, Daniel R Doerge, Kellie A Woodling, Juan E Andrade, William G Helferich, Donna L Korol, Susan L Schant. Impact of dietary genistein and aging on executive function in rats. Neurotoxicology and teratology. vol 32. issue 2. 2010-06-15. PMID:19945528. |
at the conclusion of cognitive testing, brains were collected and relative densities of d1 and d2 dopamine receptors and dopamine transporter (dat) were measured in the prefrontal cortex. |
2010-06-15 |
2023-08-12 |
rat |
| Kei Yamamoto, Jori O Ruuskanen, Mario F Wullimann, Philippe Vernie. Two tyrosine hydroxylase genes in vertebrates New dopaminergic territories revealed in the zebrafish brain. Molecular and cellular neurosciences. vol 43. issue 4. 2010-06-15. PMID:20123022. |
although these neurons have been considered to be dopamine-uptaking cells in previous studies, the expression of other monoaminergic markers such as aromatic amino acid decarboxylase (aadc), dopamine transporter (dat), and vesicular monoamine transporter 2 (vmat2) suggests that these th2 cells are dopamine-synthesizing neurons. |
2010-06-15 |
2023-08-12 |
zebrafish |
| Carolina Chavez, Marianne Hollaus, Elizabeth Scarr, Geoff Pavey, Andrea Gogos, Maarten van den Buus. The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study. Brain research. vol 1321. 2010-06-09. PMID:20079719. |
the aim of the present study was to elucidate the effect of estrogen on dopaminergic and serotonergic regulation of prepulse inhibition (ppi) by measuring its effects on the density of dopamine transporters (dat), dopamine d(1) and d(2) receptors, serotonin transporters (sert), serotonin-1a (5-ht(1a)) and 5-ht(2a) receptors using radioligand binding autoradiography. |
2010-06-09 |
2023-08-12 |
rat |
| Carolina Chavez, Marianne Hollaus, Elizabeth Scarr, Geoff Pavey, Andrea Gogos, Maarten van den Buus. The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study. Brain research. vol 1321. 2010-06-09. PMID:20079719. |
on both dat and dopamine d(2) receptor density, is involved. |
2010-06-09 |
2023-08-12 |
rat |
| Gianluigi Tanda, Amy H Newman, Jonathan L Kat. Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors. Advances in pharmacology (San Diego, Calif.). vol 57. 2010-06-08. PMID:20230764. |
stimulant drugs acting at the dopamine transporter (dat), like cocaine, are widely abused, yet effective medical treatments for this abuse have not been found. |
2010-06-08 |
2023-08-12 |
Not clear |