Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yoshihiro Takeuch. [Neurotransmission in developmental disorders]. No to hattatsu = Brain and development. vol 40. issue 6. 2009-01-07. PMID:19039985. |
the neurotransmission of dopamine in subcortical regions such as the basal ganglia and limbic areas is synaptic; on the other hand, dopamine neurotransmission in the frontal cortex is quite different, because there are very few dopamine transporters (dat) in the frontal cortex that allow dopamine to diffuse away from the dopamine synapse ("volume transmission"). |
2009-01-07 |
2023-08-12 |
Not clear |
Linda Chang, Gene-Jack Wang, Nora D Volkow, Thomas Ernst, Frank Telang, Jean Logan, Joanna S Fowle. Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse. NeuroImage. vol 42. issue 2. 2008-12-08. PMID:18579413. |
decreased dopamine transporters (dat) in the basal ganglia were shown in patients with human immunodeficiency virus (hiv) associated dementia. |
2008-12-08 |
2023-08-12 |
human |
Yong Huang, Xue-mei Jiang, Dong-jiang L. [Effects on electro-scaip acupuncture on cerebral dopamine transporter in patients with Parkinson' s disease]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 26. issue 4. 2008-04-07. PMID:16688994. |
to investigate the effect of electro-scalp acupuncture (esa) on dopamine transporter (dat) in basal ganglia (bg) of patients with parkinson's disease (pd) by single photon emission computed tomography (spect). |
2008-04-07 |
2023-08-12 |
Not clear |
C H Kim, K A Cheon, M-S Koo, Y H Ryu, J D Lee, J W Chang, H S Le. Dopamine transporter density in the basal ganglia in obsessive-compulsive disorder, measured with [123I]IPT SPECT before and after treatment with serotonin reuptake inhibitors. Neuropsychobiology. vol 55. issue 3-4. 2007-12-03. PMID:17657168. |
we performed brain spect 2 h after intravenous administration of [(123)i]ipt using a dual-head spect camera (vertex, adac, calif., usa) and analyzed the spect data, reconstructed for the assessment of the specific/nonspecific dat binding ratio in the basal ganglia. |
2007-12-03 |
2023-08-12 |
Not clear |
C H Kim, K A Cheon, M-S Koo, Y H Ryu, J D Lee, J W Chang, H S Le. Dopamine transporter density in the basal ganglia in obsessive-compulsive disorder, measured with [123I]IPT SPECT before and after treatment with serotonin reuptake inhibitors. Neuropsychobiology. vol 55. issue 3-4. 2007-12-03. PMID:17657168. |
patients with ocd after treatment with sris showed a significantly decreased dat binding ratio in the right basal ganglia compared with baseline. |
2007-12-03 |
2023-08-12 |
Not clear |
C H Kim, K A Cheon, M-S Koo, Y H Ryu, J D Lee, J W Chang, H S Le. Dopamine transporter density in the basal ganglia in obsessive-compulsive disorder, measured with [123I]IPT SPECT before and after treatment with serotonin reuptake inhibitors. Neuropsychobiology. vol 55. issue 3-4. 2007-12-03. PMID:17657168. |
a significant correlation was found between the total scores and compulsion score changes of the y-bocs and the changes of the dat binding ratio of the right basal ganglia. |
2007-12-03 |
2023-08-12 |
Not clear |
Keun-Ah Cheon, Young-Hoon Ryu, Jae-Won Kim, Dae-Yeon Ch. The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: relating to treatment response to methylphenidate. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 1. 2005-03-29. PMID:15572278. |
adhd children with 10/10 genotype (n=7) had a significantly greater increase of the dat density in basal ganglia than the children without 10/10 genotype (n=4). |
2005-03-29 |
2023-08-12 |
human |
Erik Ryding, Mats Lindström, Björn Brådvik, Martin Grabowski, Peter Bosson, Lil Träskman-Bendz, Ingmar Rosé. A new model for separation between brain dopamine and serotonin transporters in 123I-beta-CIT SPECT measurements: normal values and sex and age dependence. European journal of nuclear medicine and molecular imaging. vol 31. issue 8. 2005-02-25. PMID:15014902. |
negative correlations between age and dat were found for basal ganglia, thalami, brain stem and temporal lobes, but not for the frontal, parietal or occipital regions. |
2005-02-25 |
2023-08-12 |
human |
Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
in the present study, we investigated the dat density of the basal ganglia using iodine-123 labelled n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ([123i]ipt) single-photon emission tomography (spet) and evaluated the activity of the presynaptic dopamine function in patients with ocd. |
2004-10-05 |
2023-08-12 |
Not clear |
Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
we performed brain spet 2 h after the intravenous administration of [123i]ipt and carried out both quantitative and qualitative analyses using the obtained spet data, which were reconstructed for the assessment of the specific/non-specific dopamine transporter (dat) binding ratio in the basal ganglia. |
2004-10-05 |
2023-08-12 |
Not clear |
Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
we then investigated the correlation between the severity scores of ocd symptoms assessed with the yale-brown obsessive-compulsive scale (y-bocs) and the specific/non-specific dat binding ratio of the basal ganglia. |
2004-10-05 |
2023-08-12 |
Not clear |
Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
compared with normal control adults, patients with ocd showed a significantly increased specific/non-specific dat binding ratio in the right basal ganglia and a tendency towards an increased specific/non-specific dat binding ratio in the left basal ganglia. |
2004-10-05 |
2023-08-12 |
Not clear |
Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
no significant correlation was found between the total scores on the y-bocs and the specific/non-specific dat binding ratio of the basal ganglia. |
2004-10-05 |
2023-08-12 |
Not clear |
Beth E Fisher, Giselle M Petzinger, Kerry Nixon, Elizabeth Hogg, Samuel Bremmer, Charles K Meshul, Michael W Jakowe. Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia. Journal of neuroscience research. vol 77. issue 3. 2004-09-09. PMID:15248294. |
the expression of proteins and genes involved in basal ganglia function including the dopamine transporter (dat), tyrosine hydroxylase (th), and the dopamine d1 and d2 receptors, as well as alterations on glutamate immunolabeling were determined. |
2004-09-09 |
2023-08-12 |
mouse |
Keun-Ah Cheon, Young-Hoon Ryu, Kee Namkoong, Chan-Hyung Kim, Jae-Jin Kim, Jong Doo Le. Dopamine transporter density of the basal ganglia assessed with [123I]IPT SPECT in drug-naive children with Tourette's disorder. Psychiatry research. vol 130. issue 1. 2004-05-04. PMID:14972371. |
we performed brain spect 2 h after the intravenous administration of i-123n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane ([(123)i]ipt) and carried out both quantitative and qualitative analyses using the obtained spect data, which were reconstructed for the assessment of the specific/non-specific dat binding ratio in the basal ganglia. |
2004-05-04 |
2023-08-12 |
Not clear |
Keun-Ah Cheon, Young-Hoon Ryu, Kee Namkoong, Chan-Hyung Kim, Jae-Jin Kim, Jong Doo Le. Dopamine transporter density of the basal ganglia assessed with [123I]IPT SPECT in drug-naive children with Tourette's disorder. Psychiatry research. vol 130. issue 1. 2004-05-04. PMID:14972371. |
we then investigated the correlation between the severity of tics in children with td assessed with the yale global tic severity scale (ygtss) and the specific/non-specific dat binding ratio of the basal ganglia. |
2004-05-04 |
2023-08-12 |
Not clear |
Keun-Ah Cheon, Young-Hoon Ryu, Kee Namkoong, Chan-Hyung Kim, Jae-Jin Kim, Jong Doo Le. Dopamine transporter density of the basal ganglia assessed with [123I]IPT SPECT in drug-naive children with Tourette's disorder. Psychiatry research. vol 130. issue 1. 2004-05-04. PMID:14972371. |
drug-naive children with td showed a significantly increased specific/non-specific dat binding ratio in the basal ganglia compared with normal children that did not correlate significantly with the severity of tics. |
2004-05-04 |
2023-08-12 |
Not clear |
Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
in this study, we investigated dopamine transporter (dat) density in children with adhd using iodine-123 labelled n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ([(123)i]ipt) single-photon emission tomography (spet) and postulated that an alteration in dat density in the basal ganglia is responsible for dopaminergic dysfunction in children with adhd. |
2003-09-26 |
2023-08-12 |
Not clear |
Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
we performed brain spet 2 h after the intravenous administration of [(123)i]ipt and carried out both quantitative and qualitative analyses using the obtained spet data, which were reconstructed for the assessment of the specific/non-specific dat binding ratio in the basal ganglia. |
2003-09-26 |
2023-08-12 |
Not clear |
Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
we then investigated the correlation between the severity scores of adhd symptoms in children with adhd assessed with adhd rating scale-iv and the specific/non-specific dat binding ratio in the basal ganglia. |
2003-09-26 |
2023-08-12 |
Not clear |