| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hirotaka Sakuramoto, Hiroaki Fujita, Keitaro Ogaki, Keisuke Suzuk. Vascular parkinsonism showing dopamine transporter scan findings mimicking those of Parkinson's disease. eNeurologicalSci. vol 37. 2024-09-30. PMID:39346749. |
however, we should be aware that, as in our patient, vp patients with asymmetric basal ganglia lesions, may show increased striatal asymmetry index and asymmetric dat scan findings. |
2024-09-30 |
2024-10-02 |
Not clear |
| Bader Alkharisi, Khaled Dostzada, Harleen Kaur, Manoj Kumar, Jeanne Y Wei, Gohar Azha. The Importance of Dopamine Deficiency Evaluation in Non-Alzheimer Disease Dementias. The American journal of case reports. vol 24. 2023-04-05. PMID:37016564. |
to increase the sensitivity of current dlb guidelines, the dlb consortium published its fourth revised report in 2017 with increased diagnostic weight given to dopamine transporter (dat) uptake in the basal ganglia, demonstrated by single-photon emission computed tomography or positron emission tomography imaging. |
2023-04-05 |
2023-08-14 |
Not clear |
| Chenhao Jia, Meiqi Wu, Tzu-Chen Yen, Yanfeng Li, Ruixue Cu. Complementary Utility of Dopamine Transporter and Tau PET Imaging in the Diagnosis of Progressive Supranuclear Palsy: A Case Report. Clinical nuclear medicine. 2022-01-12. PMID:35020665. |
11c-cft pet revealed severe loss of striatal dat function, whereas significant tau accumulation was observed in the brainstem, basal ganglia, and globus pallidus on 18f-apn-1607 pet. |
2022-01-12 |
2023-08-13 |
Not clear |
| Eleanor Porter, Andreas-Antonios Roussakis, Nicholas P Lao-Kaim, Paola Piccin. Multimodal dopamine transporter (DAT) imaging and magnetic resonance imaging (MRI) to characterise early Parkinson's disease. Parkinsonism & related disorders. vol 79. 2021-11-15. PMID:32861103. |
currently, in early idiopathic pd, dopamine transporter (dat)-specific imaging assesses the extent of striatal dopaminergic deficits, and conventional magnetic resonance imaging (mri) of the brain excludes the presence of significant ischaemic load in the basal ganglia as well as signs indicative of other forms of parkinsonism. |
2021-11-15 |
2023-08-13 |
Not clear |
| Babak Tous. Diagnosis and Management of Cognitive and Behavioral Changes in Dementia With Lewy Bodies. Current treatment options in neurology. vol 19. issue 11. 2020-10-01. PMID:28990131. |
reduced dat uptake in basal ganglia demonstrated by spect or pet imaging has high specificity (90%) for distinguishing dlb from ad. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xiaohong Li, Qizhou Zhang, Yongde Qin, Yubin Li, Nazimuguli Mutaerbieke, Xiaojia Zhao, Amina Yibulayi. Positron emission tomography/computed tomography dual imaging using 18-fluorine flurodeoxyglucose and 11C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane for the severity assessment of Parkinson disease. Medicine. vol 99. issue 14. 2020-04-08. PMID:32243399. |
the characteristics of pet/ct imaging of c-cft brain dat in the ganglion region in absorbing c-cft in different pd groups are analyzed.compared with the healthy control group, changes in the cerebral glucose metabolism in the pd group mainly occur due to the increased symmetry metabolism of the nucleus of bilateral basal ganglia and the decreased metabolism of the cerebral cortex as shown in the f-fdg pet/ct images. |
2020-04-08 |
2023-08-13 |
Not clear |
| Xiaohong Li, Qizhou Zhang, Yongde Qin, Yubin Li, Nazimuguli Mutaerbieke, Xiaojia Zhao, Amina Yibulayi. Positron emission tomography/computed tomography dual imaging using 18-fluorine flurodeoxyglucose and 11C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane for the severity assessment of Parkinson disease. Medicine. vol 99. issue 14. 2020-04-08. PMID:32243399. |
regardless of unilateral or bilateral symptoms, the dat distribution in the nucleus of the contralateral basal ganglia and in the posterior part of the nucleus is substantially reduced.pet/ct dual imaging by f-fdg pet/ct combined with c-cft pet/ct features high application value for the severity assessment of pd. |
2020-04-08 |
2023-08-13 |
Not clear |
| Naveed Malek, Ravi Jampana, Donald G Grosse. Rare case of atypical parkinsonism: why family history is important. Scottish medical journal. vol 62. issue 4. 2018-10-22. PMID:29192564. |
magnetic resonance imaging scan of the brain was normal and a dat spect scan showed reduced dopamine uptake in the basal ganglia. |
2018-10-22 |
2023-08-13 |
Not clear |
| Wei Song, Marisa Cressatti, Hillel Zukor, Adrienne Liberman, Carmela Galindez, Hyman M Schippe. Parkinsonian features in aging GFAP.HMOX1 transgenic mice overexpressing human HO-1 in the astroglial compartment. Neurobiology of aging. vol 58. 2018-02-14. PMID:28746897. |
here, we show that selective overexpression of the stress protein, heme oxygenase-1 (ho-1) in astrocytes of gfap.hmox1 transgenic mice between 8.5 and 19 months of age results in nigrostriatal hypodopaminergia associated with locomotor incoordination and stereotypy; downregulation of tyrosine hydroxylase, dat, lmx1b, nurr1, pitx3 and dj-1 mrna and/or protein; overproduction of α-synuclein and ubiquitin; oxidative stress; basal ganglia siderosis; mitochondrial damage/mitophagy; and augmented gabaergic systems (increased gaba, gad67 and reelin). |
2018-02-14 |
2023-08-13 |
mouse |
| Yuji Shiga, Yuhei Kanaya, Ryuhei Kono, Shinichi Takeshima, Yutaka Shimoe, Masaru Kuriyam. Dementia with Lewy bodies presenting marked tongue protrusion and bite due to lingual dystonia: A case report. Rinsho shinkeigaku = Clinical neurology. vol 56. issue 6. 2017-03-23. PMID:27212676. |
she was diagnosed as dementia with lewy bodies (dlb) from the clinical features including progressive cognitive decline, visual hallucinations, parkinsonism, and severe insomnia and depression, and the radiological finding of low dopamine transported uptake in basal ganglia by dat scan and low blood circulation in occipital lobe of cerebrum. |
2017-03-23 |
2023-08-13 |
Not clear |
| Abigail Z Rajala, Ismail Zaitoun, Jeffrey B Henriques, Alexander K Converse, Dhanabalan Murali, Miles L Epstein, Luis C Populi. Dopamine transporter gene susceptibility to methylation is associated with impulsivity in nonhuman primates. Journal of neurophysiology. vol 112. issue 9. 2015-07-08. PMID:25122707. |
because genetic/epigenetic modifications could lead to differences in protein expression, we measured dat availability using [(18)f]2β-carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl)-nortropane ([(18)f]fecnt) pet and found higher dat availability in the internal globus pallidus, an output nucleus of the basal ganglia, of the impulsive group. |
2015-07-08 |
2023-08-13 |
human |
| Hee Kyung Park, Sun J Chun. New perspective on parkinsonism in frontotemporal lobar degeneration. Journal of movement disorders. vol 6. issue 1. 2014-06-24. PMID:24868417. |
dopamine transporter (dat) imaging revealed decreased uptake of dat, and imaging findings indicated atrophic changes of the basal ganglia. |
2014-06-24 |
2023-08-13 |
human |
| In-Uk Song, Young-Do Kim, Hyun-Ji Cho, Sung-Woo Chung, Yong-An Chun. An FP-CIT PET comparison of the differences in dopaminergic neuronal loss between idiopathic Parkinson disease with dementia and without dementia. Alzheimer disease and associated disorders. vol 27. issue 1. 2013-08-12. PMID:22354157. |
previous studies have demonstrated a decreased density of dopamine transporters (dat) in basal ganglia in patients with idiopathic parkinson disease (ipd) using i-n-fluoropropyl-2b-carbomethoxy-3b-(4-iodophenyl) nortropane (fp-cit), and the reductions in striatal dat levels were inversely correlated with the severity of motor dysfunction in ipd. |
2013-08-12 |
2023-08-12 |
Not clear |
| Noah B Gross, Patrick C Duncker, John F Marshal. Striatal dopamine D1 and D2 receptors: widespread influences on methamphetamine-induced dopamine and serotonin neurotoxicity. Synapse (New York, N.Y.). vol 65. issue 11. 2012-06-18. PMID:21584865. |
this study demonstrates that (1) dopamine d1 and d2 receptors in striatum, like nigral d1 receptors, are needed for mamph-induced striatal dat reductions, (2) these same receptors are needed for mamph-induced sert loss, and (3) these widespread influences of striatal dopamine receptor antagonists are likely attributable to circuits connecting basal ganglia to thalamus and cortex. |
2012-06-18 |
2023-08-12 |
Not clear |
| Neivo da Silva, Claudia M Szobot, Carlos E Anselmi, Andrea P Jackowski, Shih M Chi, Marcelo Q Hoexter, Osvaldo E Anselmi, Flavio Pechansky, Rodrigo A Bressan, Luis A Rohd. Attention deficit/hyperactivity disorder: is there a correlation between dopamine transporter density and cerebral blood flow? Clinical nuclear medicine. vol 36. issue 8. 2011-10-21. PMID:21716015. |
based on the hypothesis that there is a correlation between da availability and brain perfusion, we postulated that individuals with adhd, with a higher dat density in the basal ganglia, will have lower perfusion in the fronto-striatal-cerebellar networks. |
2011-10-21 |
2023-08-12 |
Not clear |
| Siroos Mirzaei, Rasoul Zakavi, Margarida Rodrigues, Thomas Schwarzgruber, Thomas Brücke, Jiri Bakala, Katalin Borbély, Norbert Leners, Peter Knoll, Rene Donne. Fully automated 3D basal ganglia activity measurement in dopamine transporter scintigraphy (Spectalyzer). Annals of nuclear medicine. vol 24. issue 4. 2010-09-10. PMID:20232177. |
semiquantitative evaluation of tracer uptake in basal ganglia is superior to visual assessment of images in dopamine transporter (dat) scintigraphy especially in follow-up of the patients. |
2010-09-10 |
2023-08-12 |
Not clear |
| Yong Huang, Xuemei Jiang, Ying Zhuo, Gustav Wi. Complementary acupuncture in Parkinson's disease: a spect study. The International journal of neuroscience. vol 120. issue 2. 2010-05-25. PMID:20199208. |
patients who received levodopa and complementary acupuncture had increased rcbf in the frontal lobe, the occipital lobe, the basal ganglion, and the cerebellum in the most affected hemisphere as compared to baseline, but there were no changes in basal ganglia dat levels. |
2010-05-25 |
2023-08-12 |
Not clear |
| S Arpin, E Lagrue, S Bodard, S Chalon, P Castelna. Basal ganglia neuroprotection with anticonvulsants after energy stress: a comparative study. Metabolic brain disease. vol 24. issue 3. 2009-12-30. PMID:19789969. |
the membrane dopamine transporter (dat) density, which provides a reliable index of dopaminergic neurons survival in the basal ganglia, was assessed by semi-quantitative autoradiography of the striatum. |
2009-12-30 |
2023-08-12 |
mouse |
| Anna Paschali, Velissarios Lakiotis, Lambros Messinis, Elli Markaki, Constantine Constantoyannis, John Ellul, Pavlos Vassilako. Dopamine transporter SPECT/CT and perfusion brain SPECT imaging in idiopathic basal ganglia calcinosis. Clinical nuclear medicine. vol 34. issue 7. 2009-09-30. PMID:19542944. |
dat spect/ct imaging revealed a reduction in dat binding in both striatum regions coinciding with bilateral calcifications in the basal ganglia. |
2009-09-30 |
2023-08-12 |
Not clear |
| E Lagrue, B Abert, L Nadal, L Tabone, S Bodard, F Medja, A Lombes, S Chalon, P Castelna. MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood. Metabolic brain disease. vol 24. issue 2. 2009-09-14. PMID:19319673. |
this model also reproduced the biochemical and pathological features of ls: mptp increased plasmatic lactate levels (p = 0.023) and triggered basal ganglia degeneration, as evaluated through dopamine transporter (dat) autoradiography, tyrosine hydroxylase (th) immunohistochemistry, and dopamine dosage. |
2009-09-14 |
2023-08-12 |
mouse |