| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
drug-naive children with adhd showed a significantly increased specific/non-specific dat binding ratio in the basal ganglia compared with normal children. |
2003-09-26 |
2023-08-12 |
Not clear |
| Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
however, no significant correlation was found between the severity scores of adhd symptoms in children with adhd and the specific/non-specific dat binding ratio in the basal ganglia. |
2003-09-26 |
2023-08-12 |
Not clear |
| R H Mach, M A Nader, R L Ehrenkaufer, H D Gage, S R Childers, L M Hodges, M M Hodges, H M Davie. Fluorine-18-labeled tropane analogs for PET imaging studies of the dopamine transporter. Synapse (New York, N.Y.). vol 37. issue 2. 2000-08-24. PMID:10881032. |
both compounds possessed a high affinity and selectivity for the dopamine transporter and had a higher accumulation in the basal ganglia, a brain region having a high density of the dopamine transporter (dat) than the cerebellum, a reference region devoid of dopaminergic terminals. |
2000-08-24 |
2023-08-12 |
Not clear |
| S Z Meng, Y Ozawa, M Itoh, S Takashim. Developmental and age-related changes of dopamine transporter, and dopamine D1 and D2 receptors in human basal ganglia. Brain research. vol 843. issue 1-2. 2000-01-24. PMID:10528120. |
the developmental and age-related changes of the dopamine transporter (dat), and the dopamine d1 and d2 receptor (d1r and d2r) subtypes were investigated in basal ganglia (bg) of human brain. |
2000-01-24 |
2023-08-12 |
human |
| M Jaber, B Bloch, M G Caron, B Giro. [Behavioral, cellular and molecular consequences of the dopamine transporter gene inactivation]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 192. issue 6. 1999-05-03. PMID:10101608. |
mice lacking the the plasma membrane dopamine transporter (dat), following gene inactivation or knock out, show an increase in their spontaneous locomotor activity that is of the same magnitude than in normal mice treated with amphetamine or cocaine, known to increase levels of dopamine in the basal ganglia. |
1999-05-03 |
2023-08-12 |
mouse |
| J T Kuikka, K Akerman, K A Bergström, J Karhu, J Hiltunen, J Haukka, J Heikkinen, J Tiihonen, S Wang, J L Neumeye. Iodine-123 labelled N-(2-fluoroethyl)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)nortropane for dopamine transporter imaging in the living human brain. European journal of nuclear medicine. vol 22. issue 7. 1996-01-17. PMID:7498231. |
the specific dat binding of [123i]beta-cit-fe into the basal ganglia was somewhat less (0.785 +/- 0.117) than that of [123i]beta-cit (0.922 +/- 0.004) or [123i]beta-cit-fp (0.813 +/- 0.047). |
1996-01-17 |
2023-08-12 |
human |
| G J Wang, N D Volkow, J S Fowler, Y S Ding, J Logan, S J Gatley, R R MacGregor, A P Wol. Comparison of two pet radioligands for imaging extrastriatal dopamine transporters in human brain. Life sciences. vol 57. issue 14. 1995-10-23. PMID:7564877. |
dat availability measured with [c-11]d-threo-methylphenidate was highest in basal ganglia, followed by thalamus > temporal insula, cingulate > orbitofrontal, frontal and occipital cortices. |
1995-10-23 |
2023-08-12 |
human |
| J T Kuikka, K A Bergström, A Ahonen, J Hiltunen, J Haukka, E Länsimies, S Wang, J L Neumeye. Comparison of iodine-123 labelled 2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and 2 beta-carbomethoxy-3 beta-(4-iodophenyl)-N-(3-fluoropropyl)nortropane for imaging of the dopamine transporter in the living human brain. European journal of nuclear medicine. vol 22. issue 4. 1995-08-16. PMID:7607268. |
however, the specific dat binding of [123i] beta-cit-fp in the basal ganglia was somewhat less (0.813 +/- 0.047) than that of [123i] beta-cit (0.922 +/- 0.004). |
1995-08-16 |
2023-08-12 |
human |
| W Gsell, R Conrad, M Hickethier, E Sofic, L Frölich, I Wichart, K Jellinger, G Moll, G Ransmayr, H Beckman. Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type. Journal of neurochemistry. vol 64. issue 3. 1995-03-17. PMID:7861154. |
enzyme activities were measured postmortem in basal ganglia, cortical, and limbic brain regions of patients with dat and age-matched controls. |
1995-03-17 |
2023-08-12 |
cat |
| W Gsell, R Conrad, M Hickethier, E Sofic, L Frölich, I Wichart, K Jellinger, G Moll, G Ransmayr, H Beckman. Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type. Journal of neurochemistry. vol 64. issue 3. 1995-03-17. PMID:7861154. |
there were significant reductions in cat activity in parietotemporal cortex, basal ganglia, and amygdala in dat compared with controls (p < 0.05 to 0.01). |
1995-03-17 |
2023-08-12 |
cat |
| K Jellinger, W Paulus, I Grundke-Iqbal, P Riederer, M B Youdi. Brain iron and ferritin in Parkinson's and Alzheimer's diseases. Journal of neural transmission. Parkinson's disease and dementia section. vol 2. issue 4. 1991-05-01. PMID:2078310. |
semiquantitative histological evaluation of brain iron and ferritin in parkinson's (pd) and alzheimer's disease (dat) have been performed in paraffin sections of brain regions which included frontal cortex, hippocampus, basal ganglia and brain stem. |
1991-05-01 |
2023-08-11 |
Not clear |