| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Milligan, V Zapata, D Schoeniger, M Chacur, P Green, S Poole, D Martin, S F Maier, L R Watkin. An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine. The European journal of neuroscience. vol 22. issue 11. 2006-02-07. PMID:16324111. |
spinal fractalkine (cx3cl1) is expressed by sensory afferents and intrinsic neurons, whereas its receptor (cx3cr1) is predominantly expressed by microglia. |
2006-02-07 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Maria Nilsson, Erik Wallström, Hans Lassmann, Tomas Olsson, Anna-Lena Berg, Anders Ericsson-Dahlstran. CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. Journal of neuroinflammation. vol 2. 2005-10-07. PMID:16053521. |
cx3cl1 (fractalkine) and cx3cr1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. |
2005-10-07 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Maria Nilsson, Erik Wallström, Hans Lassmann, Tomas Olsson, Anna-Lena Berg, Anders Ericsson-Dahlstran. CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. Journal of neuroinflammation. vol 2. 2005-10-07. PMID:16053521. |
the proposed role for cx3cl1 (fractalkine) in the control of microglia activation and leukocyte infiltration places this chemokine and its receptor cx3cr1 in a potentially strategic position to control key aspects in the pathological events that are associated with development of brain lesions in ms. |
2005-10-07 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Maria Nilsson, Erik Wallström, Hans Lassmann, Tomas Olsson, Anna-Lena Berg, Anders Ericsson-Dahlstran. CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. Journal of neuroinflammation. vol 2. 2005-10-07. PMID:16053521. |
in this study, we examine this hypothesis by analyzing the distribution, kinetics, regulation and cellular origin of cx3cl1 and cx3cr1 mrna expression in the cns of rats with an experimentally induced ms-like disease, myelin oligodendrocyte glycoprotein (mog)-induced autoimmune encephalomyelitis (eae). |
2005-10-07 |
2023-08-12 |
rat |
| Jill A Lindia, Erin McGowan, Nina Jochnowitz, Catherine Abbadi. Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. The journal of pain. vol 6. issue 7. 2005-09-08. PMID:15993821. |
induction of cx3cl1 expression in astrocytes and cx3cr1 in microglia in the spinal cord of a rat model of neuropathic pain. |
2005-09-08 |
2023-08-12 |
rat |
| Jill A Lindia, Erin McGowan, Nina Jochnowitz, Catherine Abbadi. Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. The journal of pain. vol 6. issue 7. 2005-09-08. PMID:15993821. |
the purpose of this study was to provide an immunohistochemical description of the distribution of cx3cl1 (fractalkine) and its receptor cx3cr1 in the rat spinal cord in a model of inflammatory pain induced by unilateral intraplantar complete freund's adjuvant (cfa) and in a model of neuropathic pain induced by l5 spinal nerve ligation (modified chung model or msnl). |
2005-09-08 |
2023-08-12 |
rat |
| Jill A Lindia, Erin McGowan, Nina Jochnowitz, Catherine Abbadi. Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. The journal of pain. vol 6. issue 7. 2005-09-08. PMID:15993821. |
weak immunoreactivity for the cx3cl1 receptor, cx3cr1, was found in microglia in the spinal cord of either naïve rats or rats with inflammation. |
2005-09-08 |
2023-08-12 |
rat |
| Gail M Verge, Erin D Milligan, Steve F Maier, Linda R Watkins, Gregory S Naeve, Alan C Foste. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. The European journal of neuroscience. vol 20. issue 5. 2004-11-09. PMID:15341587. |
fractalkine (cx3cl1) and fractalkine receptor (cx3cr1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. |
2004-11-09 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Erik Wallström, Lena Appelsved, Asa Malmberg, Hans Lassmann, Anders Ericsson-Dahlstrand, Fredrik Piehl, Tomas Olsso. Differential expression of the chemokine receptors CX3CR1 and CCR1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis. Brain pathology (Zurich, Switzerland). vol 13. issue 4. 2004-01-12. PMID:14655765. |
to better understand their functional roles during inflammation we have here studied the in vivo expression of receptors for the chemokines ccl3/ccl5/ccl7 (mip-1alpha/rantes/mcp-3) and cx3cl1 (fractalkine), ccr1 and cx3cr1, respectively, in rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. |
2004-01-12 |
2023-08-12 |
rat |
| Sandra Hulshof, Elise S van Haastert, Hedwich F Kuipers, Peter J van den Elsen, Corline J De Groot, Paul van der Valk, Rivka Ravid, Knut Bibe. CX3CL1 and CX3CR1 expression in human brain tissue: noninflammatory control versus multiple sclerosis. Journal of neuropathology and experimental neurology. vol 62. issue 9. 2003-10-28. PMID:14533779. |
cx3cl1 and cx3cr1 expression in human brain tissue: noninflammatory control versus multiple sclerosis. |
2003-10-28 |
2023-08-12 |
human |
| Sandra Hulshof, Elise S van Haastert, Hedwich F Kuipers, Peter J van den Elsen, Corline J De Groot, Paul van der Valk, Rivka Ravid, Knut Bibe. CX3CL1 and CX3CR1 expression in human brain tissue: noninflammatory control versus multiple sclerosis. Journal of neuropathology and experimental neurology. vol 62. issue 9. 2003-10-28. PMID:14533779. |
in this study, we compared the expression of cx3cl1 and its receptor cx3cr1 in human brain tissue derived from control patients without neurological complications and in multiple sclerosis (ms) patients. |
2003-10-28 |
2023-08-12 |
human |
| Paula Marie Hughes, Michelle Sandra Botham, Stefan Frentzel, Anis Mir, Victor Hugh Perr. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia. vol 37. issue 4. 2002-05-10. PMID:11870871. |
in a prion model of chronic neurodegeneration and inflammation, cx3cl1 immunoreactivity is upregulated in astrocytes and cx3cr1 expression is elevated on microglia. |
2002-05-10 |
2023-08-12 |
mouse |
| Paula Marie Hughes, Michelle Sandra Botham, Stefan Frentzel, Anis Mir, Victor Hugh Perr. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia. vol 37. issue 4. 2002-05-10. PMID:11870871. |
acute inflammatory responses in the cns, induced by stereotaxic injections of lipopolysaccharide or kainic acid, results in activation of microglia and astrocytes but no detectable changes in the glial expression of cx3cl1 or cx3cr1. |
2002-05-10 |
2023-08-12 |
mouse |