Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Eric S Orwoll, Paul D Miller, Jonathan D Adachi, Jacques Brown, Robert A Adler, David Kendler, Christina Bucci-Rechtweg, Aimee Readie, Peter Mesenbrink, Robert S Weinstei. Efficacy and safety of a once-yearly i.v. Infusion of zoledronic acid 5 mg versus a once-weekly 70-mg oral alendronate in the treatment of male osteoporosis: a randomized, multicenter, double-blind, active-controlled study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 25. issue 10. 2011-02-10. PMID:20499357. |
zol increased bmd at the lumbar spine, total hip, femoral neck, and trochanter and was not inferior to aln at 24 months [least squares mean estimates of the percentage increases in lumbar spine bmd of 6.1% and 6.2%; difference approximately 0.13; 95% confidence interval (ci) 1.12-0.85 in the zol and aln groups, respectively]. |
2011-02-10 |
2023-08-12 |
human |
Alexander Melamed, Eric Vittinghoff, Usha Sriram, Ann V Schwartz, Alka M Kanay. BMD reference standards among South Asians in the United States. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. vol 13. issue 4. 2011-01-20. PMID:20663699. |
the percentage of individuals reclassified when changing between reference standards varied by skeletal site and reference population origin, ranging from 13% (95% confidence interval [ci]: 7-18%), when switching from us white- to north indian-based standard for total hip, to 40% (95% ci: 32-48%), when switching from us white to south indian reference values for lumbar spine. |
2011-01-20 |
2023-08-12 |
human |
Paul D Miller, Pierre D Delmas, Hermann Huss, Katie M Patel, Ralph C Schimmer, Silvano Adami, Robert R Recke. Increases in hip and spine bone mineral density are predictive for vertebral antifracture efficacy with ibandronate. Calcified tissue international. vol 87. issue 4. 2011-01-06. PMID:20737140. |
in the oral study, total-hip bmd increases at years 2 and 3 and lumbar spine bmd increases at year 3 were associated with 3-year vertebral fracture rate (relative risk reduction [rrr] at year 3 for 1% change from baseline: hip, 7.9% [95% ci 2.1-13.5%, p = 0.0084]; lumbar spine, 4.7% [-0.1% to 9.3%, p = 0.0565]). |
2011-01-06 |
2023-08-12 |
Not clear |
Elena Lukina, Nora Watman, Elsa Avila Arreguin, Maryam Banikazemi, Marta Dragosky, Marcelo Iastrebner, Hanna Rosenbaum, Mici Phillips, Gregory M Pastores, Daniel I Rosenthal, Mathilde Kaper, Tejdip Singh, Ana Cristina Puga, Peter L Bonate, M Judith Peterschmit. A phase 2 study of eliglustat tartrate (Genz-112638), an oral substrate reduction therapy for Gaucher disease type 1. Blood. vol 116. issue 6. 2010-09-16. PMID:20439622. |
statistically significant improvements occurred in mean hemoglobin level (1.62 g/dl; 95% ci =1.05-2.18 g/dl), platelet count (40.3%; 95% ci = 23.7-57.0 g/dl), spleen volume (-38.5%; 95% ci = -43.5%--33.5%), liver volume (-17.0%; 95% ci = -21.6%-12.3%), and lumbar spine bone mineral density (0.31 z-score; 95% ci = 0.09-0.53). |
2010-09-16 |
2023-08-12 |
Not clear |
Junko Tamaki, Masayuki Iki, Yuho Sato, Etsuko Kajita, Sadanobu Kagamimori, Yoshiko Kagawa, Hideo Yoneshim. Smoking among premenopausal women is associated with increased risk of low bone status: the JPOS Study. Journal of bone and mineral metabolism. vol 28. issue 3. 2010-08-30. PMID:19830380. |
the odds ratio of an ever-smoker for low bone status at the lumbar spine was 2.03 (95% ci 1.12, 5.82) adjusted for age, height, weight, and parity. |
2010-08-30 |
2023-08-12 |
Not clear |
Junko Tamaki, Masayuki Iki, Yuho Sato, Etsuko Kajita, Sadanobu Kagamimori, Yoshiko Kagawa, Hideo Yoneshim. Smoking among premenopausal women is associated with increased risk of low bone status: the JPOS Study. Journal of bone and mineral metabolism. vol 28. issue 3. 2010-08-30. PMID:19830380. |
the odds ratio for low bone status at the lumbar spine was 1.59 (95% ci 0.65, 3.91) and 2.55 (95% ci 1.12, 5.82) in those with less than 3 pack-years of tobacco use and in those with 3 or more pack-years of tobacco use, respectively. |
2010-08-30 |
2023-08-12 |
Not clear |
Hans Jutberger, Mattias Lorentzon, Elizabeth Barrett-Connor, Helena Johansson, John A Kanis, Osten Ljunggren, Magnus K Karlsson, Björn E Rosengren, Inga Redlund-Johnell, Eric Orwoll, Claes Ohlsson, Dan Mellströ. Smoking predicts incident fractures in elderly men: Mr OS Sweden. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 25. issue 5. 2010-08-30. PMID:19929437. |
prevalent vertebral fractures among current smokers were increased in unadjusted analyses [odds ratio (or) = 1.90, 95% confidence interval (ci) 1.26-2.87] and after adjustment for lumbar bmd (or = 1.67, 95% ci 1.09-2.55). |
2010-08-30 |
2023-08-12 |
Not clear |
Alfonso Iorio, Gianluigi Fabbriciani, Maura Marcucci, Matteo Brozzetti, Paolo Filippon. Bone mineral density in haemophilia patients. A meta-analysis. Thrombosis and haemostasis. vol 103. issue 3. 2010-08-24. PMID:20076854. |
lumbar bmd was significantly lower in severe haemophilia patients than in controls, both in adult (pooled smd -1.379, 95% confidence interval [ci] -2.355 to -0.403, p=0.006) and children (pooled smd -0.438, 95% ci -0.686 to -0.189, p=0.001). |
2010-08-24 |
2023-08-12 |
Not clear |
George Moschonis, Ioanna Katsaroli, George P Lyritis, Yannis Manio. The effects of a 30-month dietary intervention on bone mineral density: the Postmenopausal Health Study. The British journal of nutrition. vol 104. issue 1. 2010-07-09. PMID:20370938. |
furthermore, a significant increase was observed for the dg in lumbar spine bmd (0.056; 95 % ci 0.009, 0.103), which was not found to differentiate significantly compared with the change observed in the cg (p = 0.075). |
2010-07-09 |
2023-08-12 |
Not clear |
Yoshifumi Maeno, Masaaki Inaba, Senji Okuno, Kaori Kohno, Kiyoshi Maekawa, Tomoyuki Yamakawa, Eiji Ishimura, Yoshiki Nishizaw. Significant association of fracture of the lumbar spine with mortality in female hemodialysis patients: a prospective observational study. Calcified tissue international. vol 85. issue 4. 2010-05-04. PMID:19763377. |
in multivariate cox proportional hazard analysis, the presence of lumbar fracture was significantly associated with increased noncardiovascular mortality (hr = 2.035, 95% ci 1.135-3.652, p < 0.05) after adjustment for age, duration of hemodialysis, presence of diabetes, body mass index, and serum calcium, phosphate, and albumin. |
2010-05-04 |
2023-08-12 |
Not clear |
Yoshifumi Maeno, Masaaki Inaba, Senji Okuno, Kaori Kohno, Kiyoshi Maekawa, Tomoyuki Yamakawa, Eiji Ishimura, Yoshiki Nishizaw. Significant association of fracture of the lumbar spine with mortality in female hemodialysis patients: a prospective observational study. Calcified tissue international. vol 85. issue 4. 2010-05-04. PMID:19763377. |
significantly higher all-cause and noncardiovascular mortality rates were also evident for patients with fracture in separate analyses in males and females, but multivariate analysis showed a significant association of lumbar fracture with increased all-cause (hr = 2.151, 95% ci 1.033-4.478, p < 0.05) and noncardiovascular (hr = 2.637, 95% ci 1.014-6.858, p < 0.05) mortality rates only in females. |
2010-05-04 |
2023-08-12 |
Not clear |
Annelie Gutke, Gunilla Kjellby-Wendt, Birgitta Ober. The inter-rater reliability of a standardised classification system for pregnancy-related lumbopelvic pain. Manual therapy. vol 15. issue 1. 2010-04-15. PMID:19632883. |
agreement for the three syndromes (lumbar pain, pgp, or combined pelvic girdle and lumbar pain) was 87% (27/31), with a kappa coefficient of 0.79 (95% ci 0.60-0.98). |
2010-04-15 |
2023-08-12 |
Not clear |
David I Sandberg, Kenneth M Crandall, Tulay Koru-Sengul, Kyle R Padgett, John Landrum, Darwin Babino, Carol K Petito, Juan Solano, Manuel Gonzalez-Brito, John W Kulu. Pharmacokinetic analysis of etoposide distribution after administration directly into the fourth ventricle in a piglet model. Journal of neuro-oncology. vol 97. issue 1. 2010-04-14. PMID:19688296. |
statistically significant differences between fourth ventricle and lumbar auc were noted at peaks (deltaauc = 3384196 ng h/ml with 95%ci: 1758625, 5009767, p = 0.0044) and at all collection time points (deltaauc = 1422977 ng h/ml with 95%ci: 732188, 2113766, p = 0.0046) but not at troughs (deltaauc = -29546 ng h/ml (95%ci: -147526, 88434.2, p = 0.5251). |
2010-04-14 |
2023-08-12 |
Not clear |
Bengt Ostman, Karl Michaëlsson, Johanna Helmersson, Liisa Byberg, Rolf Gedeborg, Håkan Melhus, Samar Bas. Oxidative stress and bone mineral density in elderly men: antioxidant activity of alpha-tocopherol. Free radical biology & medicine. vol 47. issue 5. 2009-12-07. PMID:19500667. |
men with alpha-tocopherol levels below the median combined with high oxidative stress, i.e., 8-iso-pgf(2 alpha) above the median, had 7% (95% ci 3-11%) lower bmd at the lumbar spine and 5% (95% ci 2-9%) lower bmd at the proximal femur. |
2009-12-07 |
2023-08-12 |
mouse |
A El Maghraoui, F Morjane, A Mounach, M Ghazi, A Nouijai, L Achemlal, A Bezza, I Ghozlan. Performance of calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry in the discrimination of prevalent asymptomatic osteoporotic fractures in postmenopausal women. Rheumatology international. vol 29. issue 5. 2009-09-24. PMID:18953537. |
age-adjusted ors after correction for confounding variables (years of menopause, weight, height, and bmi) for qus and bmd measurements showed that only lumbar spine t-score below -2.5 could predict significantly the presence of vfs (or, 1.94; 95%ci, 1.02-3.41). |
2009-09-24 |
2023-08-12 |
Not clear |
Steven Boonen, Eric S Orwoll, Dietrich Wenderoth, Karen J Stoner, Rachelle Eusebio, Pierre D Delma. Once-weekly risedronate in men with osteoporosis: results of a 2-year, placebo-controlled, double-blind, multicenter study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 24. issue 4. 2009-07-16. PMID:19049326. |
treatment with risedronate resulted in a significant increase from baseline to endpoint in lumbar spine bmd compared with placebo (4.5%; 95% ci: 3.5%, 5.6%; p < 0.001). |
2009-07-16 |
2023-08-12 |
Not clear |
Christian Roux, Karine Briot, Laure Gossec, Sami Kolta, Tilo Blenk, Dieter Felsenberg, David M Reid, Richard Eastell, Claus C Glüe. Increase in vertebral fracture risk in postmenopausal women using omeprazole. Calcified tissue international. vol 84. issue 1. 2009-02-19. PMID:19023510. |
the other predictors were age higher than 65 years (rr = 2.34, 95% ci 1.02-5.34), prevalent vertebral fractures (rr = 3.62, 95% ci 1.63-8.08), and lumbar spine t score = -2.5 (rr = 2.38, 95% ci 1.03-5.49). |
2009-02-19 |
2023-08-12 |
Not clear |
b' Ville M Mattila, Lea Saarni, Jari Parkkari, Leena Koivusilta, Arja Rimpel\\xc3\\xa. Early risk factors for lumbar discectomy: an 11-year follow-up of 57,408 adolescents. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 17. issue 10. 2008-12-30. PMID:18682991.' |
in multivariate cox's regression analysis, the significant risk factor for lumbar discectomy among male respondents was daily smoking, hr being 1.5 (95% ci 1.1-2.2). |
2008-12-30 |
2023-08-12 |
human |
b' Ville M Mattila, Lea Saarni, Jari Parkkari, Leena Koivusilta, Arja Rimpel\\xc3\\xa. Early risk factors for lumbar discectomy: an 11-year follow-up of 57,408 adolescents. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 17. issue 10. 2008-12-30. PMID:18682991.' |
in females, frequent participation in sports clubs (hr 2.7, 95% ci 1.1-6.3) and overweight (hr 2.1; 95% ci 1.1-4.1) were significantly associated with an increased risk of lumbar discectomy. |
2008-12-30 |
2023-08-12 |
human |
Carlos Aceves-González, Lilia R Prado-Leo. Low back pain and depression: a study in a population of Mexican workers. Work (Reading, Mass.). vol 31. issue 2. 2008-12-23. PMID:18957734. |
conditional logistic regression analysis showed that chronic lumbar spondyloarthrosis illness, when adjusted for participation in sports activity, was found to be associated with depression (or = 3.4; ci 95% 1.2-9.4). |
2008-12-23 |
2023-08-12 |
Not clear |